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Genotoxicity potential of 8-Cl-cyclic adenosine monophosphate assessed with cytogenetic tests in vivo
(Elsevier Science Inc, New York, 2004)
Background. Growth-modulating noncytotoxic activity of 8-chloro-adenosine 3,5-cyclic monophosphate (8-Cl-cAMP) showed inhibitory effect on growth of a wide variety of cancer cell lines in vitro and in vivo. To assess ...
Genotoxicity and potential chemosterilant effects of Rosol
(Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd, 1997)
Rosol is an anticoagulant rodenticide which, according to the specification of its producer (VZ-Zemun), contains 0.5 g of warfarin-sodium in 100 mililiters of solution. Its cytogenetical effects on bone marrow mitotic cells ...
Genotoxicity of the anticoccidial agent salinomycin
(Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd, 1998)
This report presents an analysis of genotoxic effects of the ionophoric antibiotic salinomycin commonly used in the control of coccidiosis. Mutagenic properties were determined, after application of increasing doses to ...
Investigation of the genotoxic effects of ivermectin on human lymphocytes
(Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd, 1996)
The genotoxic effects of ivermectin, a widely used antiparasitic drug, were investigated. It was tested in various concentrations in PHA-activated human lymphocyte cultures, for the ability to induce sister chromatid ...
Enhanced sister-chromatid exchange rate in human lymphocytes exposed to 17 beta estradiol in vitro
(Elsevier Science Inc, New York, 2002)
Background. Epidemiologic data and animal experiments strongly implicate that steroid hormones are involved in the process of malignant transformation due to their capability to stimulate mitotic division and/or elevate ...
Evaluation of genotoxic effects of fumagillin by cytogenetic tests in vivo
(Elsevier Science Bv, Amsterdam, 2007)
Fumagillin is a naturally secreted antibiotic of the fungus Aspergillus fumigates. It is used in veterinary medicine against microsporidiosis of bees and fish. In this study, the genotoxicity of fumagillin (in the form of ...
In vitro cytogenetic analysis of the effects of oxytocin on human peripheral blood lymphocytes
(Elsevier, Amsterdam, 1996)
The purpose of this study was to determine possible genotoxic and cytotoxic (or mitogenic) effects of high concentrations of oxytocin, active component of Syntocinon(R) in cultures of human peripheral blood lymphocytes. ...
The genotoxic effects of alphachlorhydrin in BALB/C laboratory mice
(Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd, 1999)
The genotoxic properties of different doses (7,5, 15 and 30 mg/kg body mass) of alphachlorchydrin were investigated in vivo in BALB/C mice and in vitro using cell cultures. Thus, mouse bone marrow cells were examined after ...