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Menthol acts as a positive allosteric modulator on nematode levamisole sensitive nicotinic acetylcholine receptors
(Elsevier Sci Ltd, Oxford, 2019)
The ongoing and widespread emergence of resistance to the existing anti-nematodal pharmacopeia has made it imperative to develop new anthelminthic agents. Historically, plants have been important sources of therapeutic ...
Monepantel is a non-competitive antagonist of nicotinic acetylcholine receptors from Ascaris suum and Oesophagostomum dentatum
(Elsevier Sci Ltd, Oxford, 2018)
Zolvix (R) is a recently introduced anthelmintic drench containing monepantel as the active ingredient. Monepantel is a positive allosteric modulator of DEG-3/DES-2 type nicotinic acetylcholine receptors (nAChRs) in several ...