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Examination of Carbadox genotoxicity in vitro and in vivo / Ispitivanje genotoksičnog efekta Carbadoxa in vitro i in vivo
(Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd, 2000)
Due to its bactericidal activity Carbadox is used for treatment of swine dysentery and salmonellosis. Also, it can be used as a factor for growth stimulation. Carbadox is the only drug for certain health problems in swine ...
Enhanced sister-chromatid exchange rate in human lymphocytes exposed to 17 beta estradiol in vitro
(Elsevier Science Inc, New York, 2002)
Background. Epidemiologic data and animal experiments strongly implicate that steroid hormones are involved in the process of malignant transformation due to their capability to stimulate mitotic division and/or elevate ...
Examination of 8-CI-cAMP genotoxicity by two in vivo test in BALB/c strain mice / Ispitivanje genotoksičnosti 8-CI-cAMP u dva in vivo testa na miševima soja BALB/c
(Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd, 2000)
The antitumor agent 8-CI-cAMP (8-chloro-cyclic adenosine monophosphate) is the most potent site-selective analogue of cAMP. It acts primarily by selective down-regulation of regulatory sub-units of cAMP-dependent protein ...
Cytogenetic analysis of the effects of epinephrine on cultured human lymphocytes / Citogenetička analiza dejstva adrenalina na humane limfocite u kulturi
(Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd, 2003)
Epinephrine can modulate mitotic activity of normal and malignant cells and exhibit genotoxic potential in some test-systems. It is assumed that metabolic conversion of phenolic groups in the catechol ring of epinephrine ...
Assessment of adrenaline-induced DNA damage in whole blood cells with the comet assay
(Inst Medical Research & Occupational Health, Zagreb, 2018)
Harmful effects of elevated levels of catecholamines are mediated by various mechanisms, including gene transcription and formation of oxidation products. The aim of this study was to see whether the molecular mechanisms ...
Monitoring of mitotic index and frequency of micronuclei in evaluation of genotoxic potential of fumagillin (dicyclohexylamine) in vivo / Praćenje mitotskog indeksa i učestalosti mikronukleusa u funkciji procene genotoksičnog potencijala fumagilina (dicikloheksilamina) in vivo
(Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd, 2006)
Fumagillin (dicyclohexylamine) is a natural antibiotic, secreted by Aspergillus fumigatus. It is used in veterinary medicine against microsporidiosis in bees and fish, as well as in human medicine for the treatment of ...