TY  - JOUR
AU  - Bošnjaković, Dušan
AU  - Nedić, Sreten
AU  - Arsić, Sveta
AU  - Prodanović, Radiša
AU  - Vujanac, Ivan
AU  - Jovanović, Ljubomir
AU  - Stojković, Milica
AU  - Jovanović, Ivan B
AU  - Đuričić, Ivana
AU  - Kirovski, Danijela
PY  - 2024
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/3929
AB  - The dairy industry contributes significantly to anthropogenic methane emissions, which
have an impact on global warming. This study aimed to investigate the effects of a dietary inclusion of brown seaweed Ascophyllum nodosum on enteric methane emissions (EMEs), hematological and blood biochemical profiles, and milk composition in dairy cows. Eighteen Holstein cows were divided into three groups: CON (non-supplemented cows), BS50 (50 mL of 10% A. nodosum), and BS100 (100 mL of 10% A. nodosum). In each cow, measurements of EME, dry matter intake (DMI), and milk yield (MY), as well as blood and milk sampling with respective analyzes, were performed before supplementation (P1), after 15 (P2) days, and after 30 (P3) days of supplementation. A. nodosum reduced (p < 0.05) methane production, methane yield, and methane intensity in both BS50 and BS100, and raised DMI (p < 0.05) only in BS50. Total bilirubin (p < 0.05) was higher in BS50 compared to CON cows in P2, and triacylglycerols were lower (p < 0.05) in BS50 than in CON cows in P3. Higher milk fat content was found in BS50 than in CON cows in P3. C16:0 proportions were higher (p < 0.05) in BS50 and BS100 than in CON cows, while C18:3n-3 was higher (p < 0.05) in BS100 than in BS50 and CON cows in P3. Dietary treatment with A. nodosum reduced EMEs and showed the potential to increase DMI and to improve energy status as well as milk composition in peaklactating dairy cows.
PB  - MDPI
T2  - Animals
T1  - Effects of brown seaweed (Ascophyllum nodosum) supplementation on enteric methane emissions, metabolic status and milk composition in peak-lactating Holstein cows
VL  - 14
SP  - 1520
DO  - 10.3390/ani14111520
ER  - 

@article{
author = "Bošnjaković, Dušan and Nedić, Sreten and Arsić, Sveta and Prodanović, Radiša and Vujanac, Ivan and Jovanović, Ljubomir and Stojković, Milica and Jovanović, Ivan B and Đuričić, Ivana and Kirovski, Danijela",
year = "2024",
abstract = "The dairy industry contributes significantly to anthropogenic methane emissions, which
have an impact on global warming. This study aimed to investigate the effects of a dietary inclusion of brown seaweed Ascophyllum nodosum on enteric methane emissions (EMEs), hematological and blood biochemical profiles, and milk composition in dairy cows. Eighteen Holstein cows were divided into three groups: CON (non-supplemented cows), BS50 (50 mL of 10% A. nodosum), and BS100 (100 mL of 10% A. nodosum). In each cow, measurements of EME, dry matter intake (DMI), and milk yield (MY), as well as blood and milk sampling with respective analyzes, were performed before supplementation (P1), after 15 (P2) days, and after 30 (P3) days of supplementation. A. nodosum reduced (p < 0.05) methane production, methane yield, and methane intensity in both BS50 and BS100, and raised DMI (p < 0.05) only in BS50. Total bilirubin (p < 0.05) was higher in BS50 compared to CON cows in P2, and triacylglycerols were lower (p < 0.05) in BS50 than in CON cows in P3. Higher milk fat content was found in BS50 than in CON cows in P3. C16:0 proportions were higher (p < 0.05) in BS50 and BS100 than in CON cows, while C18:3n-3 was higher (p < 0.05) in BS100 than in BS50 and CON cows in P3. Dietary treatment with A. nodosum reduced EMEs and showed the potential to increase DMI and to improve energy status as well as milk composition in peaklactating dairy cows.",
publisher = "MDPI",
journal = "Animals",
title = "Effects of brown seaweed (Ascophyllum nodosum) supplementation on enteric methane emissions, metabolic status and milk composition in peak-lactating Holstein cows",
volume = "14",
pages = "1520",
doi = "10.3390/ani14111520"
}

Bošnjaković, D., Nedić, S., Arsić, S., Prodanović, R., Vujanac, I., Jovanović, L., Stojković, M., Jovanović, I. B., Đuričić, I.,& Kirovski, D.. (2024). Effects of brown seaweed (Ascophyllum nodosum) supplementation on enteric methane emissions, metabolic status and milk composition in peak-lactating Holstein cows. in Animals
MDPI., 14, 1520.
https://doi.org/10.3390/ani14111520

Bošnjaković D, Nedić S, Arsić S, Prodanović R, Vujanac I, Jovanović L, Stojković M, Jovanović IB, Đuričić I, Kirovski D. Effects of brown seaweed (Ascophyllum nodosum) supplementation on enteric methane emissions, metabolic status and milk composition in peak-lactating Holstein cows. in Animals. 2024;14:1520.
doi:10.3390/ani14111520 .

Bošnjaković, Dušan, Nedić, Sreten, Arsić, Sveta, Prodanović, Radiša, Vujanac, Ivan, Jovanović, Ljubomir, Stojković, Milica, Jovanović, Ivan B, Đuričić, Ivana, Kirovski, Danijela, "Effects of brown seaweed (Ascophyllum nodosum) supplementation on enteric methane emissions, metabolic status and milk composition in peak-lactating Holstein cows" in Animals, 14 (2024):1520,
https://doi.org/10.3390/ani14111520 . .

TY  - CONF
AU  - Vujanac, Ivan
AU  - Prodanović, Radiša
AU  - Nedić, Sreten
AU  - Arsić, Sveta
AU  - Mitrović, Aleksandra
AU  - Bojkovski, Jovan
AU  - Simić, Aleksandar
AU  - Jovanović, Ljubomir
AU  - Bošnjaković, Dušan
AU  - Kirovski, Danijela
PY  - 2024
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/3722
AB  - Hromost goveda predstavlja značajan zdravstveni problem, a sa
aspekta ekonomskog značaja nalazi se odmah iza poremećaja u reprodukciji.
Prosečna incidenca hromosti na farmama mlečnih krava
je oko 7%. Međutim, ona se kreće u širokom rasponu od 5 pa sve do
60%, a stopa isključenja krava iz stada zbog oboljenja papaka je od
5 do 10%.
Razvoj hromosti kod mlečnih krava je uslovljena sinergističkim
delovanjem mnogobrojnih činilaca od izlaganja metaboličkom stresu
na početku laktacije, mehaničkom delovanju tvrdih i grubih betonskih
podova, kratkih ležišta, konstantnog izlaganja rožine papaka vlažnoj
prostirci, kao i neblagovremenog korigovanja rožine papaka ili nestručne
korekcije.
Veći udeo koncentrovanih hraniva bogatih energijom u odnosu
na kabasti deo obroka doprinosi pojavi oboljenja papaka, što ukazuje
da prevencija acidoze buraga u stadima predstavlja bitan činilac u
kontroli hromosti kod goveda. Sa intenziviranjem procesa fermentacije
lako svarljivih ugljenih – hidrata u buragu opada vredost pH sadržaja,
povećava se propustljivost sluzokože kako za endotoksine bakterija,
tako i za de novo sintetisane vazoaktivne amine (histamin, serotonin,
bradikinin) koji dovode do poremećaja mikrocirkulacije u korijumu
papaka. Supakutna acidoza buraga i metabolički poremećaji zdravlja
tokom rane laktacije su glavni etiološki činioci za bolesti papaka kako
neinfektivne, tako i infektivne etiologije.
PB  - Beograd : Fakultet veterinarske medicine, Centar za izdavačku delatnost i promet učila
C3  - XLV seminar za inovacije znanja veterinara, Beograd, 23. februar 2024
T1  - Hromost – zdravstveni i ekonomski problem na farmama visokomlečnih krava
SP  - 119
EP  - 126
UR  - https://hdl.handle.net/21.15107/rcub_veterinar_3722
ER  - 

@conference{
author = "Vujanac, Ivan and Prodanović, Radiša and Nedić, Sreten and Arsić, Sveta and Mitrović, Aleksandra and Bojkovski, Jovan and Simić, Aleksandar and Jovanović, Ljubomir and Bošnjaković, Dušan and Kirovski, Danijela",
year = "2024",
abstract = "Hromost goveda predstavlja značajan zdravstveni problem, a sa
aspekta ekonomskog značaja nalazi se odmah iza poremećaja u reprodukciji.
Prosečna incidenca hromosti na farmama mlečnih krava
je oko 7%. Međutim, ona se kreće u širokom rasponu od 5 pa sve do
60%, a stopa isključenja krava iz stada zbog oboljenja papaka je od
5 do 10%.
Razvoj hromosti kod mlečnih krava je uslovljena sinergističkim
delovanjem mnogobrojnih činilaca od izlaganja metaboličkom stresu
na početku laktacije, mehaničkom delovanju tvrdih i grubih betonskih
podova, kratkih ležišta, konstantnog izlaganja rožine papaka vlažnoj
prostirci, kao i neblagovremenog korigovanja rožine papaka ili nestručne
korekcije.
Veći udeo koncentrovanih hraniva bogatih energijom u odnosu
na kabasti deo obroka doprinosi pojavi oboljenja papaka, što ukazuje
da prevencija acidoze buraga u stadima predstavlja bitan činilac u
kontroli hromosti kod goveda. Sa intenziviranjem procesa fermentacije
lako svarljivih ugljenih – hidrata u buragu opada vredost pH sadržaja,
povećava se propustljivost sluzokože kako za endotoksine bakterija,
tako i za de novo sintetisane vazoaktivne amine (histamin, serotonin,
bradikinin) koji dovode do poremećaja mikrocirkulacije u korijumu
papaka. Supakutna acidoza buraga i metabolički poremećaji zdravlja
tokom rane laktacije su glavni etiološki činioci za bolesti papaka kako
neinfektivne, tako i infektivne etiologije.",
publisher = "Beograd : Fakultet veterinarske medicine, Centar za izdavačku delatnost i promet učila",
journal = "XLV seminar za inovacije znanja veterinara, Beograd, 23. februar 2024",
title = "Hromost – zdravstveni i ekonomski problem na farmama visokomlečnih krava",
pages = "119-126",
url = "https://hdl.handle.net/21.15107/rcub_veterinar_3722"
}

Vujanac, I., Prodanović, R., Nedić, S., Arsić, S., Mitrović, A., Bojkovski, J., Simić, A., Jovanović, L., Bošnjaković, D.,& Kirovski, D.. (2024). Hromost – zdravstveni i ekonomski problem na farmama visokomlečnih krava. in XLV seminar za inovacije znanja veterinara, Beograd, 23. februar 2024
Beograd : Fakultet veterinarske medicine, Centar za izdavačku delatnost i promet učila., 119-126.
https://hdl.handle.net/21.15107/rcub_veterinar_3722

Vujanac I, Prodanović R, Nedić S, Arsić S, Mitrović A, Bojkovski J, Simić A, Jovanović L, Bošnjaković D, Kirovski D. Hromost – zdravstveni i ekonomski problem na farmama visokomlečnih krava. in XLV seminar za inovacije znanja veterinara, Beograd, 23. februar 2024. 2024;:119-126.
https://hdl.handle.net/21.15107/rcub_veterinar_3722 .

Vujanac, Ivan, Prodanović, Radiša, Nedić, Sreten, Arsić, Sveta, Mitrović, Aleksandra, Bojkovski, Jovan, Simić, Aleksandar, Jovanović, Ljubomir, Bošnjaković, Dušan, Kirovski, Danijela, "Hromost – zdravstveni i ekonomski problem na farmama visokomlečnih krava" in XLV seminar za inovacije znanja veterinara, Beograd, 23. februar 2024 (2024):119-126,
https://hdl.handle.net/21.15107/rcub_veterinar_3722 .

TY  - JOUR
AU  - Prodanović, Radiša
AU  - Nedić, Sreten
AU  - Bošnjaković, Dušan
AU  - Nedić, Svetlana
AU  - Jovanović, Ljubomir
AU  - Arsić, Sveta
AU  - Bojkovski, Jovan
AU  - Borozan, Sunčica
AU  - Kirovski, Danijela
AU  - Vujanac, Ivan
PY  - 2024
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/3784
AB  - Due to their antiketogenic and antioxidant effects, chestnut
tannins may offer a viable approach to manage the impaired immune and
renal functions in transition cows. This study aimed to investigate the effects of
dietary supplementation with chestnut tannins on haematological, biochemical
and antioxidant indices, as well as cortisol levels in prepartum dairy cows.
Forty multiparous Holstein cows were divided into two homogeneous groups
(n = 20): a control (CON), and an experimental group (CNT) receiving
20 g/day of chestnut tannins for the last 25 ± 2 days of pregnancy. Haematological
and biochemical indices, cortisol concentration and total antioxidant capacity
(T-AOC) were measured in blood samples collected 25 (day −25) and 5 days
(day −5) before the expected parturition. The addition of chestnut tannins
exerted no significant effect on red blood cells indices; however, white blood cell
(P = 0.02), lymphocyte (P = 0.05) and platelet (P < 0.01) counts were higher,
while the neutrophil to lymphocyte ratio (P = 0.03) was lower on day −5 in the
CNT group compared to the CON group. Significantly higher values of T-AOC
(P = 0.03) and significantly lower levels of triglycerides (P = 0.03) and gammaglutamyl
transferase (P = 0.02) were also found in CNT compared to CON on
day −5. The improved haematological profile in CNT cows was accompanied
by lower serum creatinine concentration (P = 0.04), while total protein, calcium,
phosphorus and cortisol did not differ significantly between CNT and CON cows.
These data demonstrate that dietary chestnut tannin supplementation in a closeup
diet has antioxidant and anti-inflammatory effects, and could potentially mitigate
immune suppression and kidney dysfunction near parturition. Further research
should be conducted concerning the mechanisms underlying these responses.
PB  - Kielanowski Institute of Animal Physiology and Nutrition, Polish Academy of Sciences in Jabłonna (Poland)
PB  - Kielanowski
T2  - Journal of Animal and Feed Sciences
T1  - Chestnut tannin supplementation can improve immune response and kidney function in prepartum dairy cows
VL  - 33
IS  - 2
SP  - 185
EP  - 192
DO  - 10.22358/jafs/174065/2023
ER  - 

@article{
author = "Prodanović, Radiša and Nedić, Sreten and Bošnjaković, Dušan and Nedić, Svetlana and Jovanović, Ljubomir and Arsić, Sveta and Bojkovski, Jovan and Borozan, Sunčica and Kirovski, Danijela and Vujanac, Ivan",
year = "2024",
abstract = "Due to their antiketogenic and antioxidant effects, chestnut
tannins may offer a viable approach to manage the impaired immune and
renal functions in transition cows. This study aimed to investigate the effects of
dietary supplementation with chestnut tannins on haematological, biochemical
and antioxidant indices, as well as cortisol levels in prepartum dairy cows.
Forty multiparous Holstein cows were divided into two homogeneous groups
(n = 20): a control (CON), and an experimental group (CNT) receiving
20 g/day of chestnut tannins for the last 25 ± 2 days of pregnancy. Haematological
and biochemical indices, cortisol concentration and total antioxidant capacity
(T-AOC) were measured in blood samples collected 25 (day −25) and 5 days
(day −5) before the expected parturition. The addition of chestnut tannins
exerted no significant effect on red blood cells indices; however, white blood cell
(P = 0.02), lymphocyte (P = 0.05) and platelet (P < 0.01) counts were higher,
while the neutrophil to lymphocyte ratio (P = 0.03) was lower on day −5 in the
CNT group compared to the CON group. Significantly higher values of T-AOC
(P = 0.03) and significantly lower levels of triglycerides (P = 0.03) and gammaglutamyl
transferase (P = 0.02) were also found in CNT compared to CON on
day −5. The improved haematological profile in CNT cows was accompanied
by lower serum creatinine concentration (P = 0.04), while total protein, calcium,
phosphorus and cortisol did not differ significantly between CNT and CON cows.
These data demonstrate that dietary chestnut tannin supplementation in a closeup
diet has antioxidant and anti-inflammatory effects, and could potentially mitigate
immune suppression and kidney dysfunction near parturition. Further research
should be conducted concerning the mechanisms underlying these responses.",
publisher = "Kielanowski Institute of Animal Physiology and Nutrition, Polish Academy of Sciences in Jabłonna (Poland), Kielanowski",
journal = "Journal of Animal and Feed Sciences",
title = "Chestnut tannin supplementation can improve immune response and kidney function in prepartum dairy cows",
volume = "33",
number = "2",
pages = "185-192",
doi = "10.22358/jafs/174065/2023"
}

Prodanović, R., Nedić, S., Bošnjaković, D., Nedić, S., Jovanović, L., Arsić, S., Bojkovski, J., Borozan, S., Kirovski, D.,& Vujanac, I.. (2024). Chestnut tannin supplementation can improve immune response and kidney function in prepartum dairy cows. in Journal of Animal and Feed Sciences
Kielanowski Institute of Animal Physiology and Nutrition, Polish Academy of Sciences in Jabłonna (Poland)., 33(2), 185-192.
https://doi.org/10.22358/jafs/174065/2023

Prodanović R, Nedić S, Bošnjaković D, Nedić S, Jovanović L, Arsić S, Bojkovski J, Borozan S, Kirovski D, Vujanac I. Chestnut tannin supplementation can improve immune response and kidney function in prepartum dairy cows. in Journal of Animal and Feed Sciences. 2024;33(2):185-192.
doi:10.22358/jafs/174065/2023 .

Prodanović, Radiša, Nedić, Sreten, Bošnjaković, Dušan, Nedić, Svetlana, Jovanović, Ljubomir, Arsić, Sveta, Bojkovski, Jovan, Borozan, Sunčica, Kirovski, Danijela, Vujanac, Ivan, "Chestnut tannin supplementation can improve immune response and kidney function in prepartum dairy cows" in Journal of Animal and Feed Sciences, 33, no. 2 (2024):185-192,
https://doi.org/10.22358/jafs/174065/2023 . .

TY  - CONF
AU  - Arsić, Sveta
AU  - Nedić, Sreten
AU  - Prodanović, Radiša
AU  - Bojkovski, Jovan
AU  - Mitrović, Aleksandra
AU  - Ninković, Milan
AU  - Milčić, Staniša
AU  - Savić, Zoran
AU  - Vukomanović, Igor
AU  - Vujanac, Ivan
PY  - 2024
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/3903
AB  - Dislokacija sirišta je značajan zdravstveni problem u patologiji
digestivnog trakta visokomlečnih krava. Ona predstavlja topografsku gastropatiju
koja se pojavljuje u više oblika: kao dislokacija sirišta na levo, dislokacija sirišta na desno
i torzija sirišta. Na nivou stada visokomlečnih krava, dislokacija sirišta je široko
rasprostranjeno oboljenje goveda, čija učestalost pojavljivanja iznosi oko 5%. Od ukupnog
broja obolelih životinja, prevalencija levostrane dislokacije iznosi oko 80%, dok se
ostali oblici promene položaja sirišta pojavljuju ređe. Pored direktnog uticaja na zdravstveni
status i smanjenje proizvodnje mleka kod obolelih životinja, ovo oboljenje ima i
negativan uticaj na plodnost krava. Tokom poslednjih šezdeset godina, razvijeno je više
metoda lečenja dislokacije sirišta, od konzervativnih do hiruških tehnika koje daju najviše
izgleda za povoljan ishod. Klasične hirurške metode lečenja imaju za cilj repoziciju
sirišta u anatomski normalan položaj i njegovu fiksaciju za abdominalni zid. Sa razvojem
savremenih tehnika u humanoj medicini, u poslednje dve decenije značajno mesto
u hirurškom trertmanu dislokacije sirišta zauzimaju i laparoskopske tehnike koje su
minimalno invazivne. U odnosu na klasične hirurške tehnike, laparoskopska fiksacija
sirišta ima nekoliko prednosti. Pored manje traume, bolja je abdominalna vizuelizacija,
jednostavna je za izvođenje, brza, manje stresna po životinju i primenljiva je u svim
terenskim uslovima.
PB  - Beograd : Udruženje veterinara praktičara Srbije (UVPS)
C3  - VI Simpozijum sa međunarodnim učešćem - Zdravstvena zaštita i reprodukcija papkara, kopitara, živine i mesojeda, Beograd, 18 - 20. april 2024
T1  - Uspešnost različitih tretmana repozicije dislociranog sirišta kod krava
SP  - 41
EP  - 50
UR  - https://hdl.handle.net/21.15107/rcub_veterinar_3903
ER  - 

@conference{
author = "Arsić, Sveta and Nedić, Sreten and Prodanović, Radiša and Bojkovski, Jovan and Mitrović, Aleksandra and Ninković, Milan and Milčić, Staniša and Savić, Zoran and Vukomanović, Igor and Vujanac, Ivan",
year = "2024",
abstract = "Dislokacija sirišta je značajan zdravstveni problem u patologiji
digestivnog trakta visokomlečnih krava. Ona predstavlja topografsku gastropatiju
koja se pojavljuje u više oblika: kao dislokacija sirišta na levo, dislokacija sirišta na desno
i torzija sirišta. Na nivou stada visokomlečnih krava, dislokacija sirišta je široko
rasprostranjeno oboljenje goveda, čija učestalost pojavljivanja iznosi oko 5%. Od ukupnog
broja obolelih životinja, prevalencija levostrane dislokacije iznosi oko 80%, dok se
ostali oblici promene položaja sirišta pojavljuju ređe. Pored direktnog uticaja na zdravstveni
status i smanjenje proizvodnje mleka kod obolelih životinja, ovo oboljenje ima i
negativan uticaj na plodnost krava. Tokom poslednjih šezdeset godina, razvijeno je više
metoda lečenja dislokacije sirišta, od konzervativnih do hiruških tehnika koje daju najviše
izgleda za povoljan ishod. Klasične hirurške metode lečenja imaju za cilj repoziciju
sirišta u anatomski normalan položaj i njegovu fiksaciju za abdominalni zid. Sa razvojem
savremenih tehnika u humanoj medicini, u poslednje dve decenije značajno mesto
u hirurškom trertmanu dislokacije sirišta zauzimaju i laparoskopske tehnike koje su
minimalno invazivne. U odnosu na klasične hirurške tehnike, laparoskopska fiksacija
sirišta ima nekoliko prednosti. Pored manje traume, bolja je abdominalna vizuelizacija,
jednostavna je za izvođenje, brza, manje stresna po životinju i primenljiva je u svim
terenskim uslovima.",
publisher = "Beograd : Udruženje veterinara praktičara Srbije (UVPS)",
journal = "VI Simpozijum sa međunarodnim učešćem - Zdravstvena zaštita i reprodukcija papkara, kopitara, živine i mesojeda, Beograd, 18 - 20. april 2024",
title = "Uspešnost različitih tretmana repozicije dislociranog sirišta kod krava",
pages = "41-50",
url = "https://hdl.handle.net/21.15107/rcub_veterinar_3903"
}

Arsić, S., Nedić, S., Prodanović, R., Bojkovski, J., Mitrović, A., Ninković, M., Milčić, S., Savić, Z., Vukomanović, I.,& Vujanac, I.. (2024). Uspešnost različitih tretmana repozicije dislociranog sirišta kod krava. in VI Simpozijum sa međunarodnim učešćem - Zdravstvena zaštita i reprodukcija papkara, kopitara, živine i mesojeda, Beograd, 18 - 20. april 2024
Beograd : Udruženje veterinara praktičara Srbije (UVPS)., 41-50.
https://hdl.handle.net/21.15107/rcub_veterinar_3903

Arsić S, Nedić S, Prodanović R, Bojkovski J, Mitrović A, Ninković M, Milčić S, Savić Z, Vukomanović I, Vujanac I. Uspešnost različitih tretmana repozicije dislociranog sirišta kod krava. in VI Simpozijum sa međunarodnim učešćem - Zdravstvena zaštita i reprodukcija papkara, kopitara, živine i mesojeda, Beograd, 18 - 20. april 2024. 2024;:41-50.
https://hdl.handle.net/21.15107/rcub_veterinar_3903 .

Arsić, Sveta, Nedić, Sreten, Prodanović, Radiša, Bojkovski, Jovan, Mitrović, Aleksandra, Ninković, Milan, Milčić, Staniša, Savić, Zoran, Vukomanović, Igor, Vujanac, Ivan, "Uspešnost različitih tretmana repozicije dislociranog sirišta kod krava" in VI Simpozijum sa međunarodnim učešćem - Zdravstvena zaštita i reprodukcija papkara, kopitara, živine i mesojeda, Beograd, 18 - 20. april 2024 (2024):41-50,
https://hdl.handle.net/21.15107/rcub_veterinar_3903 .

TY  - CONF
AU  - Jovanović, Ljubomir
AU  - Bošnjaković, Dušan
AU  - Stojković, Milica
AU  - Dražić, Slavica
AU  - Vujanac, Ivan
AU  - Prodanović, Radiša
AU  - Arsić, Sveta
AU  - Nedić, Sreten
AU  - Kirovski, Danijela
PY  - 2024
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/3720
AB  - Govedarska proizvodnja je značajan izvor gasova sa efektom
staklene bašte, prevashodno metana, s obzirom da preko 20 % ukupne
globalne emisije ovog gasa potiče iz govedarske proizvodnje. U
proceni mogućnosti za smanjenje emisije metana sa farmi mora se
uzeti u obzir i proizvodnja. Zato se emisija metana najčešće izražava
po jedinici proizvoda, odnosno kilogramu dobijenog mesa ili mleka.
Preporučljivo je da se u obzir uzme i nutritivna vrednost proizvoda
i tada se emisija metana izražava po kilogramu otkoštenog mesa
ili kilogramu mleka korigovanog na standardan sadržaj masti i proteina
u mleku (3,5% i 3,02%, pojedinačno). Metodološki, procena emisije
metana od strane individualne životinje povezana je sa razvojem
osetljivih, specifičnih i pouzdanih metoda. Budući da najveći deo emisije
metana na govedarskim farmama čini enterički metan, razvoj metodologije
je napredovao u pravcu njegove detekcije i kvantifikacije u
izdahnutom ili podrignutom vazduhu. Na enteričku emisiju metana utiče
veliki broj faktora kao što su ishrana, genetika, zdravstveno stanje,
menadžment farme, što sugeriše da je strategije za smanjenje emisije
metana neophodno prilagoditi uslovima koji su karakteristični za određenu
farmu. Za veterinare praktičare je neophodno poznavanje ovih
faktora i primena metoda za njihovu manipulaciju i korekciju u cilju
uspostavljanja održive i ekološki prihvatljive govedarske proizvodnje.
PB  - Beograd : Fakultet veterinarske medicine, Centar za izdavačku delatnost i promet učila
C3  - XLV seminar za inovacije znanja veterinara, Beograd, 23. februar 2024
T1  - Procena održivosti i ekološke prihvatljivosti govedarske proizvodnje sa posebnim osvrtom na emisiju metana – metodološki pristup
SP  - 109
EP  - 118
UR  - https://hdl.handle.net/21.15107/rcub_veterinar_3720
ER  - 

@conference{
author = "Jovanović, Ljubomir and Bošnjaković, Dušan and Stojković, Milica and Dražić, Slavica and Vujanac, Ivan and Prodanović, Radiša and Arsić, Sveta and Nedić, Sreten and Kirovski, Danijela",
year = "2024",
abstract = "Govedarska proizvodnja je značajan izvor gasova sa efektom
staklene bašte, prevashodno metana, s obzirom da preko 20 % ukupne
globalne emisije ovog gasa potiče iz govedarske proizvodnje. U
proceni mogućnosti za smanjenje emisije metana sa farmi mora se
uzeti u obzir i proizvodnja. Zato se emisija metana najčešće izražava
po jedinici proizvoda, odnosno kilogramu dobijenog mesa ili mleka.
Preporučljivo je da se u obzir uzme i nutritivna vrednost proizvoda
i tada se emisija metana izražava po kilogramu otkoštenog mesa
ili kilogramu mleka korigovanog na standardan sadržaj masti i proteina
u mleku (3,5% i 3,02%, pojedinačno). Metodološki, procena emisije
metana od strane individualne životinje povezana je sa razvojem
osetljivih, specifičnih i pouzdanih metoda. Budući da najveći deo emisije
metana na govedarskim farmama čini enterički metan, razvoj metodologije
je napredovao u pravcu njegove detekcije i kvantifikacije u
izdahnutom ili podrignutom vazduhu. Na enteričku emisiju metana utiče
veliki broj faktora kao što su ishrana, genetika, zdravstveno stanje,
menadžment farme, što sugeriše da je strategije za smanjenje emisije
metana neophodno prilagoditi uslovima koji su karakteristični za određenu
farmu. Za veterinare praktičare je neophodno poznavanje ovih
faktora i primena metoda za njihovu manipulaciju i korekciju u cilju
uspostavljanja održive i ekološki prihvatljive govedarske proizvodnje.",
publisher = "Beograd : Fakultet veterinarske medicine, Centar za izdavačku delatnost i promet učila",
journal = "XLV seminar za inovacije znanja veterinara, Beograd, 23. februar 2024",
title = "Procena održivosti i ekološke prihvatljivosti govedarske proizvodnje sa posebnim osvrtom na emisiju metana – metodološki pristup",
pages = "109-118",
url = "https://hdl.handle.net/21.15107/rcub_veterinar_3720"
}

Jovanović, L., Bošnjaković, D., Stojković, M., Dražić, S., Vujanac, I., Prodanović, R., Arsić, S., Nedić, S.,& Kirovski, D.. (2024). Procena održivosti i ekološke prihvatljivosti govedarske proizvodnje sa posebnim osvrtom na emisiju metana – metodološki pristup. in XLV seminar za inovacije znanja veterinara, Beograd, 23. februar 2024
Beograd : Fakultet veterinarske medicine, Centar za izdavačku delatnost i promet učila., 109-118.
https://hdl.handle.net/21.15107/rcub_veterinar_3720

Jovanović L, Bošnjaković D, Stojković M, Dražić S, Vujanac I, Prodanović R, Arsić S, Nedić S, Kirovski D. Procena održivosti i ekološke prihvatljivosti govedarske proizvodnje sa posebnim osvrtom na emisiju metana – metodološki pristup. in XLV seminar za inovacije znanja veterinara, Beograd, 23. februar 2024. 2024;:109-118.
https://hdl.handle.net/21.15107/rcub_veterinar_3720 .

Jovanović, Ljubomir, Bošnjaković, Dušan, Stojković, Milica, Dražić, Slavica, Vujanac, Ivan, Prodanović, Radiša, Arsić, Sveta, Nedić, Sreten, Kirovski, Danijela, "Procena održivosti i ekološke prihvatljivosti govedarske proizvodnje sa posebnim osvrtom na emisiju metana – metodološki pristup" in XLV seminar za inovacije znanja veterinara, Beograd, 23. februar 2024 (2024):109-118,
https://hdl.handle.net/21.15107/rcub_veterinar_3720 .

TY  - JOUR
AU  - Bojkovski, Jovan
AU  - Nedić, Sreten
AU  - Arsić, Sveta
AU  - Vujanac, Ivan
AU  - Prodanović, Radiša
AU  - Mitrović, Aleksandra
AU  - Đurić, Miloje
AU  - Bugarski, Dejan
AU  - Panousis, Nikolaos K.
AU  - Kalaitzakis, Emmanouil
AU  - Ninković, Milan
PY  - 2023
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/3928
AB  - The lameness is the earliest but also the most important clinical symptom of the acropodium disease in cattle. According to literature data, in 90% of cases, the cause of lameness is localized in the hooves, and in 10% of cases it is in other anatomical parts of the limb. In 88% of cases, the pathological process has been manifested at the hind limbs. Laminitis is an aseptic inflammation of the corium of the hooves. In addition to mechanical overloading of the hooves, the toxic causes are also addressed as the causes of this disease. Longer feeding with rapidly digested concentrate, rumen acidosis, sudden change of food components, especially diet with green barley, oat, freshly harvested young legumes and nutrition with molded food, can lead to laminitis. Laminitis is often the result of impact of a large number of factors, such as metabolic and digestive disorders, calving stress, mastitis, metritis, abomasal displacement, bedding without or with very little straw, inability to move, obesity and poor diet. The ration that leads to acidosis also leads to laminitis. Such a ration is difficult to correct in a case when the carbohydrates are present in highest percentage. Vasoactive substances (histamine), which enter the bloodstream from rumen, are considered to lead to damage of the hoof corium. Metabolic disorder is caused by a low pH of rumen, which leads to pathophysiological disorders, which eventually result in the ischemia of the hoof corium and clinically manifest laminitis (leg disposal due to pain, and sometimes forced lying). In addition to histamine and bacterial endotoxins, milk acids and others biologically active substances are believed to contribute to the onset of this disease. The application of basic principles of the nutrition of the lactating cows can prevent the appearance of laminitis and therefore the appearance of economic losses due to lameness.
PB  - Banja Luka : PI Veterinary Institute Republic of Srpska "Dr. Vaso Butozan"
T2  - Veterinarski žurnal Republike Srpske
T1  - Pathogenesis of laminitis in dairy cows
VL  - 23
IS  - 1-2
SP  - 307
EP  - 317
DO  - 10.7251/VETJEN2301307B
ER  - 

@article{
author = "Bojkovski, Jovan and Nedić, Sreten and Arsić, Sveta and Vujanac, Ivan and Prodanović, Radiša and Mitrović, Aleksandra and Đurić, Miloje and Bugarski, Dejan and Panousis, Nikolaos K. and Kalaitzakis, Emmanouil and Ninković, Milan",
year = "2023",
abstract = "The lameness is the earliest but also the most important clinical symptom of the acropodium disease in cattle. According to literature data, in 90% of cases, the cause of lameness is localized in the hooves, and in 10% of cases it is in other anatomical parts of the limb. In 88% of cases, the pathological process has been manifested at the hind limbs. Laminitis is an aseptic inflammation of the corium of the hooves. In addition to mechanical overloading of the hooves, the toxic causes are also addressed as the causes of this disease. Longer feeding with rapidly digested concentrate, rumen acidosis, sudden change of food components, especially diet with green barley, oat, freshly harvested young legumes and nutrition with molded food, can lead to laminitis. Laminitis is often the result of impact of a large number of factors, such as metabolic and digestive disorders, calving stress, mastitis, metritis, abomasal displacement, bedding without or with very little straw, inability to move, obesity and poor diet. The ration that leads to acidosis also leads to laminitis. Such a ration is difficult to correct in a case when the carbohydrates are present in highest percentage. Vasoactive substances (histamine), which enter the bloodstream from rumen, are considered to lead to damage of the hoof corium. Metabolic disorder is caused by a low pH of rumen, which leads to pathophysiological disorders, which eventually result in the ischemia of the hoof corium and clinically manifest laminitis (leg disposal due to pain, and sometimes forced lying). In addition to histamine and bacterial endotoxins, milk acids and others biologically active substances are believed to contribute to the onset of this disease. The application of basic principles of the nutrition of the lactating cows can prevent the appearance of laminitis and therefore the appearance of economic losses due to lameness.",
publisher = "Banja Luka : PI Veterinary Institute Republic of Srpska "Dr. Vaso Butozan"",
journal = "Veterinarski žurnal Republike Srpske",
title = "Pathogenesis of laminitis in dairy cows",
volume = "23",
number = "1-2",
pages = "307-317",
doi = "10.7251/VETJEN2301307B"
}

Bojkovski, J., Nedić, S., Arsić, S., Vujanac, I., Prodanović, R., Mitrović, A., Đurić, M., Bugarski, D., Panousis, N. K., Kalaitzakis, E.,& Ninković, M.. (2023). Pathogenesis of laminitis in dairy cows. in Veterinarski žurnal Republike Srpske
Banja Luka : PI Veterinary Institute Republic of Srpska "Dr. Vaso Butozan"., 23(1-2), 307-317.
https://doi.org/10.7251/VETJEN2301307B

Bojkovski J, Nedić S, Arsić S, Vujanac I, Prodanović R, Mitrović A, Đurić M, Bugarski D, Panousis NK, Kalaitzakis E, Ninković M. Pathogenesis of laminitis in dairy cows. in Veterinarski žurnal Republike Srpske. 2023;23(1-2):307-317.
doi:10.7251/VETJEN2301307B .

Bojkovski, Jovan, Nedić, Sreten, Arsić, Sveta, Vujanac, Ivan, Prodanović, Radiša, Mitrović, Aleksandra, Đurić, Miloje, Bugarski, Dejan, Panousis, Nikolaos K., Kalaitzakis, Emmanouil, Ninković, Milan, "Pathogenesis of laminitis in dairy cows" in Veterinarski žurnal Republike Srpske, 23, no. 1-2 (2023):307-317,
https://doi.org/10.7251/VETJEN2301307B . .

TY  - JOUR
AU  - Bojkovski, Jovan
AU  - Nedić, Sreten
AU  - Arsić, Sveta
AU  - Vujanac, Ivan
AU  - Prodanović, Radiša
AU  - Mitrović, Aleksandra
AU  - Đurić, Miloje
AU  - Bugarski, Dejan
AU  - Panousis, Nikolaos K.
AU  - Kalaitzakis, Emmanouil
AU  - Ninković, Milan
PY  - 2023
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/3927
AB  - Hromost je najraniji ali i najvažniji klinički simptom oboljenja akropodijuma goveda. Prema literaturnim podacima u 90 % slučajeva uzrok hromosti je lokalizovan u papcima, a u 10 % slučajeva je u drugim anatomskim delovima ekstremiteta. Patološki proces je u 88 % slučajeva ispoljen na zadnjim ekstremitetima. Laminitis predstavlja aseptično zapaljenje korijuma papaka. Kao uzroci nastanka ovog oboljenja, pored mehaničkog preopterećenja papaka, navode se i toksični uzroci. Duže davanje lako svarljive koncentrovane hrane, stvaranje acidoze u buragu, nagla promena hrane, posebno ishrana zelenim ječmom, ovsem, sveže pokošenim mladim leguminozama i ishrana plesnivom hranom, mogu dovesti do pojave laminitisa. Laminitis je često rezultat uticaja velikog broja činioca, kao što su metabolički i digestivni poremećaji, porođaj stres, mastitis, metritis, dislokacija sirišta, ležište bez ili sa vrlo malo prostirke, nemogućnost kretanja, pregojenost i loš menadžment ishrane. Obrok koji dovodi do acidoze dovodi i do laminitisa. Takav obrok je vrlo težak za korekciju, kada se najveći procenat hraniva u obroku sastoji od ugljenohidratnih materija. Smatra se da vazoaktivne materije (histamin), koje ulaze u krvotok iz buraga, dovode do oštećenja korijuma papaka. Metabolički poremećaj nastaje usled niskog pH sadržaja buraga i lančano dolazi do patofizioloških poremećaja, koji na kraju rezultiraju ishemijom korijuma papaka i klinički manifestnim laminitisom (odlaganjem nogu zbog bola, a ponekad i prinudnog ležanja). Veruje se da osim histamina i bakterijski endotoksini, mlečna kiselina i druge biološki aktivne materije doprinose nastanku ovog oboljenja. Primena osnovnih principa ishrane muznih krava mogu prevenirati pojavu laminitisa samim tim i pojavu ekonomskih gubitaka usled hromosti.
PB  - Banja Luka : JU Veterinarski institut Republike Srpske "Dr Vaso Butozan"
T2  - Veterinarski žurnal Republike Srpske
T1  - Patogeneza laminitisa mlečnih krava
VL  - 23
IS  - 1-2
SP  - 295
EP  - 306
DO  - 10.7251/VETJSR2301295B
ER  - 

@article{
author = "Bojkovski, Jovan and Nedić, Sreten and Arsić, Sveta and Vujanac, Ivan and Prodanović, Radiša and Mitrović, Aleksandra and Đurić, Miloje and Bugarski, Dejan and Panousis, Nikolaos K. and Kalaitzakis, Emmanouil and Ninković, Milan",
year = "2023",
abstract = "Hromost je najraniji ali i najvažniji klinički simptom oboljenja akropodijuma goveda. Prema literaturnim podacima u 90 % slučajeva uzrok hromosti je lokalizovan u papcima, a u 10 % slučajeva je u drugim anatomskim delovima ekstremiteta. Patološki proces je u 88 % slučajeva ispoljen na zadnjim ekstremitetima. Laminitis predstavlja aseptično zapaljenje korijuma papaka. Kao uzroci nastanka ovog oboljenja, pored mehaničkog preopterećenja papaka, navode se i toksični uzroci. Duže davanje lako svarljive koncentrovane hrane, stvaranje acidoze u buragu, nagla promena hrane, posebno ishrana zelenim ječmom, ovsem, sveže pokošenim mladim leguminozama i ishrana plesnivom hranom, mogu dovesti do pojave laminitisa. Laminitis je često rezultat uticaja velikog broja činioca, kao što su metabolički i digestivni poremećaji, porođaj stres, mastitis, metritis, dislokacija sirišta, ležište bez ili sa vrlo malo prostirke, nemogućnost kretanja, pregojenost i loš menadžment ishrane. Obrok koji dovodi do acidoze dovodi i do laminitisa. Takav obrok je vrlo težak za korekciju, kada se najveći procenat hraniva u obroku sastoji od ugljenohidratnih materija. Smatra se da vazoaktivne materije (histamin), koje ulaze u krvotok iz buraga, dovode do oštećenja korijuma papaka. Metabolički poremećaj nastaje usled niskog pH sadržaja buraga i lančano dolazi do patofizioloških poremećaja, koji na kraju rezultiraju ishemijom korijuma papaka i klinički manifestnim laminitisom (odlaganjem nogu zbog bola, a ponekad i prinudnog ležanja). Veruje se da osim histamina i bakterijski endotoksini, mlečna kiselina i druge biološki aktivne materije doprinose nastanku ovog oboljenja. Primena osnovnih principa ishrane muznih krava mogu prevenirati pojavu laminitisa samim tim i pojavu ekonomskih gubitaka usled hromosti.",
publisher = "Banja Luka : JU Veterinarski institut Republike Srpske "Dr Vaso Butozan"",
journal = "Veterinarski žurnal Republike Srpske",
title = "Patogeneza laminitisa mlečnih krava",
volume = "23",
number = "1-2",
pages = "295-306",
doi = "10.7251/VETJSR2301295B"
}

Bojkovski, J., Nedić, S., Arsić, S., Vujanac, I., Prodanović, R., Mitrović, A., Đurić, M., Bugarski, D., Panousis, N. K., Kalaitzakis, E.,& Ninković, M.. (2023). Patogeneza laminitisa mlečnih krava. in Veterinarski žurnal Republike Srpske
Banja Luka : JU Veterinarski institut Republike Srpske "Dr Vaso Butozan"., 23(1-2), 295-306.
https://doi.org/10.7251/VETJSR2301295B

Bojkovski J, Nedić S, Arsić S, Vujanac I, Prodanović R, Mitrović A, Đurić M, Bugarski D, Panousis NK, Kalaitzakis E, Ninković M. Patogeneza laminitisa mlečnih krava. in Veterinarski žurnal Republike Srpske. 2023;23(1-2):295-306.
doi:10.7251/VETJSR2301295B .

Bojkovski, Jovan, Nedić, Sreten, Arsić, Sveta, Vujanac, Ivan, Prodanović, Radiša, Mitrović, Aleksandra, Đurić, Miloje, Bugarski, Dejan, Panousis, Nikolaos K., Kalaitzakis, Emmanouil, Ninković, Milan, "Patogeneza laminitisa mlečnih krava" in Veterinarski žurnal Republike Srpske, 23, no. 1-2 (2023):295-306,
https://doi.org/10.7251/VETJSR2301295B . .

TY  - JOUR
AU  - Bošnjaković, Dušan
AU  - Kirovski, Danijela
AU  - Prodanović, Radiša
AU  - Vujanac, Ivan
AU  - Arsić, Sveta
AU  - Stojković, Milica
AU  - Dražić, Slavica
AU  - Nedić, Sreten
AU  - Jovanović, Ljubomir
PY  - 2023
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/2814
AB  - Ruminant husbandry contributes to global methane (CH4) emissions and beside its negative impact on the environment, enteric CH4 emissions cause a loss of gross energy intake in cows. The study is aimed to estimate CH4 emission and metabolic status in dairy cows via the methane concentration profile as a tool for analyzing the CH4 production pattern. The study included eighteen cows whose enteric CH4 emission was measured during three consecutive days in three periods: 2 hours before (P1), 2-4 hours (P2) and 6-8 hours (P3) after the morning feeding. Based on CH4 enteric emissions, cows were divided into two groups (n=6, respectively): HM (average CH4 concentration: 5430.08 ± 365.92 ppm) and LM (average CH4 concentration: 1351.85 ± 205.20 ppm). Following CH4 measurement, on day 3, venous blood was sampled to determine the indicators of the metabolic status. HM cows had significantly higher average CH4 concentrations, maximum and average CH4 peak amplitude than LM cows in all measuring periods (P1-P3), while the number of CH4 peaks tended to be higher in HM than in LM cows in P2. There were no differences in the maximum and average CH4 peak width and average distance among two CH4 peaks between examined groups of cows. HM cows had significantly higher total protein concentrations and significantly lower total bilirubin and NEFA concentrations than LM cows. In conclusion, HM cows have a greater number of eructations and release more CH4 per eructation than LM cows, hence the differences in metabolic status are most likely related to the differences in their liver function.
PB  - Sciendo
T2  - Acta Veterinaria
T1  - Methane Emission and Metabolic Status in Peak Lactating Dairy Cows and Their Assessment Via Methane Concentration Profile
VL  - 73
VL  - 1
SP  - 71
EP  - 86
DO  - 10.2478/acve-2023-0006
ER  - 

@article{
author = "Bošnjaković, Dušan and Kirovski, Danijela and Prodanović, Radiša and Vujanac, Ivan and Arsić, Sveta and Stojković, Milica and Dražić, Slavica and Nedić, Sreten and Jovanović, Ljubomir",
year = "2023",
abstract = "Ruminant husbandry contributes to global methane (CH4) emissions and beside its negative impact on the environment, enteric CH4 emissions cause a loss of gross energy intake in cows. The study is aimed to estimate CH4 emission and metabolic status in dairy cows via the methane concentration profile as a tool for analyzing the CH4 production pattern. The study included eighteen cows whose enteric CH4 emission was measured during three consecutive days in three periods: 2 hours before (P1), 2-4 hours (P2) and 6-8 hours (P3) after the morning feeding. Based on CH4 enteric emissions, cows were divided into two groups (n=6, respectively): HM (average CH4 concentration: 5430.08 ± 365.92 ppm) and LM (average CH4 concentration: 1351.85 ± 205.20 ppm). Following CH4 measurement, on day 3, venous blood was sampled to determine the indicators of the metabolic status. HM cows had significantly higher average CH4 concentrations, maximum and average CH4 peak amplitude than LM cows in all measuring periods (P1-P3), while the number of CH4 peaks tended to be higher in HM than in LM cows in P2. There were no differences in the maximum and average CH4 peak width and average distance among two CH4 peaks between examined groups of cows. HM cows had significantly higher total protein concentrations and significantly lower total bilirubin and NEFA concentrations than LM cows. In conclusion, HM cows have a greater number of eructations and release more CH4 per eructation than LM cows, hence the differences in metabolic status are most likely related to the differences in their liver function.",
publisher = "Sciendo",
journal = "Acta Veterinaria",
title = "Methane Emission and Metabolic Status in Peak Lactating Dairy Cows and Their Assessment Via Methane Concentration Profile",
volume = "73, 1",
pages = "71-86",
doi = "10.2478/acve-2023-0006"
}

Bošnjaković, D., Kirovski, D., Prodanović, R., Vujanac, I., Arsić, S., Stojković, M., Dražić, S., Nedić, S.,& Jovanović, L.. (2023). Methane Emission and Metabolic Status in Peak Lactating Dairy Cows and Their Assessment Via Methane Concentration Profile. in Acta Veterinaria
Sciendo., 73, 71-86.
https://doi.org/10.2478/acve-2023-0006

Bošnjaković D, Kirovski D, Prodanović R, Vujanac I, Arsić S, Stojković M, Dražić S, Nedić S, Jovanović L. Methane Emission and Metabolic Status in Peak Lactating Dairy Cows and Their Assessment Via Methane Concentration Profile. in Acta Veterinaria. 2023;73:71-86.
doi:10.2478/acve-2023-0006 .

Bošnjaković, Dušan, Kirovski, Danijela, Prodanović, Radiša, Vujanac, Ivan, Arsić, Sveta, Stojković, Milica, Dražić, Slavica, Nedić, Sreten, Jovanović, Ljubomir, "Methane Emission and Metabolic Status in Peak Lactating Dairy Cows and Their Assessment Via Methane Concentration Profile" in Acta Veterinaria, 73 (2023):71-86,
https://doi.org/10.2478/acve-2023-0006 . .

TY  - JOUR
AU  - Prodanović, Radiša
AU  - Nedić, Sreten
AU  - Vujanac, Ivan
AU  - Bojkovski, Jovan
AU  - Nedić, Svetlana
AU  - Jovanović, Ljubomir
AU  - Kirovski, Danijela
AU  - Borozan, Sunčica
PY  - 2023
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/2860
AB  - Cows in the peripartal period undergo changes in thyroid hormones and are susceptible to lipomobilization and/or oxidative stress. The addition of chestnut tannins as polyphenolic compounds in the diet may improve feed efficiency and prevent oxidative stress-related health disorders in transition cows. However, the relationship between chestnut tannin supplementation and thyroid function, which plays an important role in metabolic regulation, has not been investigated in dairy cows. This study was conducted to investigate the effects of chestnut tannin supplementation during the close-up period on thyroid status and to evaluate the interaction between thyroid hormones and oxidative stress biomarkers in prepartum dairy cows. Forty multiparous Holstein cows were fed either a diet containing chestnut tannins (CNTs, n = 20, 1.96 g chestnut tannins/kg feed, dry matter) or a non-supplemented diet (CON, n = 20) during the last 25 ± 2 days of gestation. Blood samples were collected on the first day of study (before chestnut tannin supplementation) and d 5 before parturition to measure hormonal and oxidative stress indices. Serum concentrations of T3 (p = 0.04) and T4 (p = 0.05) were higher in CNT cows than in the CON group on day 5 before parturition. Thyroid status of CNT cows was associated with higher serum total antioxidant capacity (T-AOC, p < 0.01), activities of superoxide dismutase (SOD, p = 0.03) and glutathione peroxidase (GPx, p = 0.01), and reduced glutathione concentration (GSH, p = 0.05). Serum thiobarbituric acid reactive substances (TBARS) were lower (p = 0.04) which was associated with lower aspartate aminotransferase (AST, p = 0.02), and lactate dehydrogenase (LDH, p = 0.01) activities in the CNT than in the CON group. Estradiol and progesterone did not differ between CNT and CON cows. Chestnut tannin supplementation improves antioxidant protection, prevents oxidation-reduction processes, reduces the degree of liver cell membrane damage, and protects thyroid tissue from damage, allowing higher T3 and T4 synthesis. Considering the importance of the thyroid hormone status before parturition, mechanisms of thyroid hormone regulation in CNT-supplemented dairy cows require more detailed investigations.
PB  - MDPI
T2  - Metabolites
T1  - Dietary Supplementation of Chestnut Tannins in Prepartum Dairy Cows Improves Antioxidant Defense Mechanisms Interacting with Thyroid Status
VL  - 13
IS  - 3
SP  - 334
DO  - 10.3390/metabo13030334
ER  - 

@article{
author = "Prodanović, Radiša and Nedić, Sreten and Vujanac, Ivan and Bojkovski, Jovan and Nedić, Svetlana and Jovanović, Ljubomir and Kirovski, Danijela and Borozan, Sunčica",
year = "2023",
abstract = "Cows in the peripartal period undergo changes in thyroid hormones and are susceptible to lipomobilization and/or oxidative stress. The addition of chestnut tannins as polyphenolic compounds in the diet may improve feed efficiency and prevent oxidative stress-related health disorders in transition cows. However, the relationship between chestnut tannin supplementation and thyroid function, which plays an important role in metabolic regulation, has not been investigated in dairy cows. This study was conducted to investigate the effects of chestnut tannin supplementation during the close-up period on thyroid status and to evaluate the interaction between thyroid hormones and oxidative stress biomarkers in prepartum dairy cows. Forty multiparous Holstein cows were fed either a diet containing chestnut tannins (CNTs, n = 20, 1.96 g chestnut tannins/kg feed, dry matter) or a non-supplemented diet (CON, n = 20) during the last 25 ± 2 days of gestation. Blood samples were collected on the first day of study (before chestnut tannin supplementation) and d 5 before parturition to measure hormonal and oxidative stress indices. Serum concentrations of T3 (p = 0.04) and T4 (p = 0.05) were higher in CNT cows than in the CON group on day 5 before parturition. Thyroid status of CNT cows was associated with higher serum total antioxidant capacity (T-AOC, p < 0.01), activities of superoxide dismutase (SOD, p = 0.03) and glutathione peroxidase (GPx, p = 0.01), and reduced glutathione concentration (GSH, p = 0.05). Serum thiobarbituric acid reactive substances (TBARS) were lower (p = 0.04) which was associated with lower aspartate aminotransferase (AST, p = 0.02), and lactate dehydrogenase (LDH, p = 0.01) activities in the CNT than in the CON group. Estradiol and progesterone did not differ between CNT and CON cows. Chestnut tannin supplementation improves antioxidant protection, prevents oxidation-reduction processes, reduces the degree of liver cell membrane damage, and protects thyroid tissue from damage, allowing higher T3 and T4 synthesis. Considering the importance of the thyroid hormone status before parturition, mechanisms of thyroid hormone regulation in CNT-supplemented dairy cows require more detailed investigations.",
publisher = "MDPI",
journal = "Metabolites",
title = "Dietary Supplementation of Chestnut Tannins in Prepartum Dairy Cows Improves Antioxidant Defense Mechanisms Interacting with Thyroid Status",
volume = "13",
number = "3",
pages = "334",
doi = "10.3390/metabo13030334"
}

Prodanović, R., Nedić, S., Vujanac, I., Bojkovski, J., Nedić, S., Jovanović, L., Kirovski, D.,& Borozan, S.. (2023). Dietary Supplementation of Chestnut Tannins in Prepartum Dairy Cows Improves Antioxidant Defense Mechanisms Interacting with Thyroid Status. in Metabolites
MDPI., 13(3), 334.
https://doi.org/10.3390/metabo13030334

Prodanović R, Nedić S, Vujanac I, Bojkovski J, Nedić S, Jovanović L, Kirovski D, Borozan S. Dietary Supplementation of Chestnut Tannins in Prepartum Dairy Cows Improves Antioxidant Defense Mechanisms Interacting with Thyroid Status. in Metabolites. 2023;13(3):334.
doi:10.3390/metabo13030334 .

Prodanović, Radiša, Nedić, Sreten, Vujanac, Ivan, Bojkovski, Jovan, Nedić, Svetlana, Jovanović, Ljubomir, Kirovski, Danijela, Borozan, Sunčica, "Dietary Supplementation of Chestnut Tannins in Prepartum Dairy Cows Improves Antioxidant Defense Mechanisms Interacting with Thyroid Status" in Metabolites, 13, no. 3 (2023):334,
https://doi.org/10.3390/metabo13030334 . .

TY  - CONF
AU  - Jovanović, Ljubomir
AU  - Bošnjaković, Dušan
AU  - Dražić, Slavica
AU  - Nedić, Sreten
AU  - Prodanović, Radiša
AU  - Arsić, Sveta
AU  - Vujanac, Ivan
AU  - Kirovski, Danijela
PY  - 2023
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/2938
AB  - Uzgoj preživača godišnje ispusti 80-95 milijuna tona metana u zemljinu atmosferu, što istraživanje pre­hrambenih strategija za smanjenje emisija ovog stakleničkog plina čini velikim znanstvenim izazovom. Kako bi se ispitala učinkovitost korištenih strategija, potrebno je sagledati čimbenike koji utječu na emi­siju enteričkog metana, poput režima hranjenja i sastava obroka. Dodatni problem je složena metodologija određivanja emisije metana, a znanost je u potrazi za pouzdanom, jednostavnom i minimalno invazivnom metodom. Cilj ovog istraživanja bio je jednostavnom i neinvazivnom metodom (prijenosni plinski anali­ zator BIOGAS 5000) ispitati varijacije enteričke emisije metana u odnosu na vrijeme hranidbe visokomli­ječnih krava u vrhuncu laktacije. Istraživanjem je obuhvaćeno 18 holstajn-frizijskih krava, čija je enterička emisija metana mjerena tijekom 3 uzastopna dana u 3 razdoblja: 2 sata prije jutarnjeg hranjenja (Pl), 2-4 sata (P2) i 6-8 sati (P3) nakon jutarnjeg hranjenja. Emisije metana iz buraga mjerene su iz smjese izdah­nutih plinova neprekidno tijekom 3 minute i očitavanjem koncentracije metana (ppm) svakih 5 sekundi. Rezultati istraživanja pokazuju da je enterička emisija metana imala rastući trend od Pl do P3 s prosječnim vrijednostima (±standardna pogreška) od 2209±284 ppm, 3052±329 ppm i 4791±857 ppm za Pl, P2 i P3, redom. Koncentracije metana bile su značajno više u P2 nego u Pl (p=0,01), kao iu P3 u odnosu na P2 (p=0,02) i Pl (p<0,001). Zaključno, emisija enteričkog metana značajno se povećava od razdoblja prije uzi­manja, do 6-8 sati nakon uzimanja jutarnjeg obroka. Korištena metoda detekcije metana pokazala se pouz­danom.
AB  - Ruminant farming releases 80-95 million tons of methane into the Earths atmosphere annual/; making research onnutritional strategies to reduce emissions of this greenhouse gas a major scientific challenge. To study the effectiveness of the strategies used, it is necessary to take into account all the factors that influence the emission of enteric methane, such as the feeding regime and the composition of the diet. Another problem is the complex methodology of methane emission determination, and scientists are sear­ ching for a reliable, simple, and minimally invasive method. The aim of this study was to investigate the variation of intestinal methane emissions in relation to feeding time of dairy cows in peak lactation using a simple and non-invasive method (portable gas analyzer BIOGAS 5000). The study included 18 Holstein­ Friesian cows whose enteric methane emissions were measured on three consecutive days in three peri­ ods: 2 hours bff.fore morningfeeding (Pl), 2-4 hours (P2) and 6-8 hours (P3) after morningfeeding. Ente­ ric methane emissions were measured continuously from exhaled gases for 3 minutes, with methane concentration (ppm) readings every 5 seconds. Our results show that enteric methane emission had an increasing trend from Pl to P3 with average values (±standard error) of 2209±284 ppm, 3052±329 ppm, and 4791±857 ppm for Pl, P2, and P3, respectively. Methane concentrations were significantly higher in P2 than in Pl (p=0.01), as well as in P3 compared to P2 (p=0.02) and Pl (p < 0.001). In conclusion, the emission of enteric methane increases significantly from the period of intake, up to 6-8 hours after intake of the morning meal. The method used for methane detection proved to be reliable.
PB  - Zagreb : Krmiva d.o.o.
C3  - XXVIII Međunarodno savjetovanje Krmiva 2023, Opatija, 31. maj - 2. jun 2023
T1  - Utjecaj unosa hrane na dnevnu varijaciju emisije metana utvrđenu neinvazivnom metodom kod visokomliječnih krava na vrhuncu laktacije
T1  - The effect of dietary intake on the daily methane emissions determined by a non-invasive method in peak lactating dairy cattle
SP  - 27
EP  - 28
UR  - https://hdl.handle.net/21.15107/rcub_veterinar_2938
ER  - 

@conference{
author = "Jovanović, Ljubomir and Bošnjaković, Dušan and Dražić, Slavica and Nedić, Sreten and Prodanović, Radiša and Arsić, Sveta and Vujanac, Ivan and Kirovski, Danijela",
year = "2023",
abstract = "Uzgoj preživača godišnje ispusti 80-95 milijuna tona metana u zemljinu atmosferu, što istraživanje pre­hrambenih strategija za smanjenje emisija ovog stakleničkog plina čini velikim znanstvenim izazovom. Kako bi se ispitala učinkovitost korištenih strategija, potrebno je sagledati čimbenike koji utječu na emi­siju enteričkog metana, poput režima hranjenja i sastava obroka. Dodatni problem je složena metodologija određivanja emisije metana, a znanost je u potrazi za pouzdanom, jednostavnom i minimalno invazivnom metodom. Cilj ovog istraživanja bio je jednostavnom i neinvazivnom metodom (prijenosni plinski anali­ zator BIOGAS 5000) ispitati varijacije enteričke emisije metana u odnosu na vrijeme hranidbe visokomli­ječnih krava u vrhuncu laktacije. Istraživanjem je obuhvaćeno 18 holstajn-frizijskih krava, čija je enterička emisija metana mjerena tijekom 3 uzastopna dana u 3 razdoblja: 2 sata prije jutarnjeg hranjenja (Pl), 2-4 sata (P2) i 6-8 sati (P3) nakon jutarnjeg hranjenja. Emisije metana iz buraga mjerene su iz smjese izdah­nutih plinova neprekidno tijekom 3 minute i očitavanjem koncentracije metana (ppm) svakih 5 sekundi. Rezultati istraživanja pokazuju da je enterička emisija metana imala rastući trend od Pl do P3 s prosječnim vrijednostima (±standardna pogreška) od 2209±284 ppm, 3052±329 ppm i 4791±857 ppm za Pl, P2 i P3, redom. Koncentracije metana bile su značajno više u P2 nego u Pl (p=0,01), kao iu P3 u odnosu na P2 (p=0,02) i Pl (p<0,001). Zaključno, emisija enteričkog metana značajno se povećava od razdoblja prije uzi­manja, do 6-8 sati nakon uzimanja jutarnjeg obroka. Korištena metoda detekcije metana pokazala se pouz­danom., Ruminant farming releases 80-95 million tons of methane into the Earths atmosphere annual/; making research onnutritional strategies to reduce emissions of this greenhouse gas a major scientific challenge. To study the effectiveness of the strategies used, it is necessary to take into account all the factors that influence the emission of enteric methane, such as the feeding regime and the composition of the diet. Another problem is the complex methodology of methane emission determination, and scientists are sear­ ching for a reliable, simple, and minimally invasive method. The aim of this study was to investigate the variation of intestinal methane emissions in relation to feeding time of dairy cows in peak lactation using a simple and non-invasive method (portable gas analyzer BIOGAS 5000). The study included 18 Holstein­ Friesian cows whose enteric methane emissions were measured on three consecutive days in three peri­ ods: 2 hours bff.fore morningfeeding (Pl), 2-4 hours (P2) and 6-8 hours (P3) after morningfeeding. Ente­ ric methane emissions were measured continuously from exhaled gases for 3 minutes, with methane concentration (ppm) readings every 5 seconds. Our results show that enteric methane emission had an increasing trend from Pl to P3 with average values (±standard error) of 2209±284 ppm, 3052±329 ppm, and 4791±857 ppm for Pl, P2, and P3, respectively. Methane concentrations were significantly higher in P2 than in Pl (p=0.01), as well as in P3 compared to P2 (p=0.02) and Pl (p < 0.001). In conclusion, the emission of enteric methane increases significantly from the period of intake, up to 6-8 hours after intake of the morning meal. The method used for methane detection proved to be reliable.",
publisher = "Zagreb : Krmiva d.o.o.",
journal = "XXVIII Međunarodno savjetovanje Krmiva 2023, Opatija, 31. maj - 2. jun 2023",
title = "Utjecaj unosa hrane na dnevnu varijaciju emisije metana utvrđenu neinvazivnom metodom kod visokomliječnih krava na vrhuncu laktacije, The effect of dietary intake on the daily methane emissions determined by a non-invasive method in peak lactating dairy cattle",
pages = "27-28",
url = "https://hdl.handle.net/21.15107/rcub_veterinar_2938"
}

Jovanović, L., Bošnjaković, D., Dražić, S., Nedić, S., Prodanović, R., Arsić, S., Vujanac, I.,& Kirovski, D.. (2023). Utjecaj unosa hrane na dnevnu varijaciju emisije metana utvrđenu neinvazivnom metodom kod visokomliječnih krava na vrhuncu laktacije. in XXVIII Međunarodno savjetovanje Krmiva 2023, Opatija, 31. maj - 2. jun 2023
Zagreb : Krmiva d.o.o.., 27-28.
https://hdl.handle.net/21.15107/rcub_veterinar_2938

Jovanović L, Bošnjaković D, Dražić S, Nedić S, Prodanović R, Arsić S, Vujanac I, Kirovski D. Utjecaj unosa hrane na dnevnu varijaciju emisije metana utvrđenu neinvazivnom metodom kod visokomliječnih krava na vrhuncu laktacije. in XXVIII Međunarodno savjetovanje Krmiva 2023, Opatija, 31. maj - 2. jun 2023. 2023;:27-28.
https://hdl.handle.net/21.15107/rcub_veterinar_2938 .

Jovanović, Ljubomir, Bošnjaković, Dušan, Dražić, Slavica, Nedić, Sreten, Prodanović, Radiša, Arsić, Sveta, Vujanac, Ivan, Kirovski, Danijela, "Utjecaj unosa hrane na dnevnu varijaciju emisije metana utvrđenu neinvazivnom metodom kod visokomliječnih krava na vrhuncu laktacije" in XXVIII Međunarodno savjetovanje Krmiva 2023, Opatija, 31. maj - 2. jun 2023 (2023):27-28,
https://hdl.handle.net/21.15107/rcub_veterinar_2938 .

TY  - CONF
AU  - Nedić, Sreten
AU  - Vujanac, Ivan
AU  - Prodanović, Radiša
AU  - Bojkovski, Jovan
AU  - Arsić, Sveta
AU  - Bošnjaković, Dušan
AU  - Jovanović, Ljubomir
AU  - Kirovski, Danijela
PY  - 2023
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/2999
AB  - Анализа метаболичког профила представља одређивање биохемијских
параметара крви значајних за процену здравственог статуса и производних
перформанси код високо-млечних крава. Посебан значај анализе
метаболичког профила огледа се у процени искористивости хранљивих
материја оброка код крава у различитим фазама производно репродуктивног
циклуса, односно о њиховом енергетском, протеинском и минералном
статусу. Поред тога, анализа метаболичког профила омогућава нам
правовремено откривање супклиничких и клиничких постпарталних обољења
која су повезана са лактацијом и репродукцијом, што представља приоритет
на савременим фармама високо-млечних крава, јер ти фактори значајно утичу
на рентабилност производње. У рутинској анализи метаболичког профила у
стадима високо-млечних крава одређују се концентрације глукозе,
бетахидроксибутерне киселине (БХБ), укупних протеина, албумина,
калцијума, фосфора, урее, укупног билирубина, триглицерида као и активност
ензима јетре аспартат-аминотрансферазе (АСТ) и гама-глутамилтрансферазе
(ГГТ). Број параметара метаболичког профила зависи од етиологије и
патогенезе обољења на фарми која могу да се испољавају у клиничкој и
супклиничкој форми. Такође, одређивање параметара метаболичког профила
треба да се обави у свим фазама производно-репродуктивног циклуса крава,
засушење, пуерперијум и лактација, као и да се обухвати репрезентативан број
животиња на фарми. Значај анализе метаболичког профила на високо-
млечним фармама огледа се у његовој предности над осталим дијагностичким
процедурама у сагледавању и откривању како здравствених проблема, тако ипроцени снабдевености и искористивости хранљивих материја из оброка. На
тај начин, омогућава се превениција као и благовремена терапија
метаболичких и других здравствених проблема код високом-млечних крава,
чиме се одржава здравље стада на високом нивоу. На основу свега наведеног
може се закључити да анализа метаболичког профила директно доприноси
одрживој фармској производњи, чији је главни аспект очување здравља
животиња и минималан негативан утицај на животну средину.
AB  - Metabolic profile analysis represents the determination of blood biochemical
parameters important for the assessment of health status and production
performance of high-yielding dairy cows. The particular importance of metabolic
profile analysis is reflected in the evaluation of feed nutrient utilization in cows
at different stages of the production and reproduction cycle, i.e. their energy,
protein and mineral status. In addition, metabolic profile analysis allows timely
detection of subclinical and clinical postpartum diseases related to lactation and
reproduction, which is of primary importance in modern dairy farms, as these
factors significantly affect the profitability of production. Routine analysis of the
metabolic profile in herds of high-yielding dairy cows includes determination of
concentrations of glucose, beta-hydroxybutyric acid (BHB), total proteins,
albumin, calcium, phosphorus, urea, total bilirubin, triglycerides, and activity of
the liver enzymes aspartate aminotransferase (AST) and gamma-
glutamyltransferase (GGT). The number of parameters of the metabolic profile
depends on the etiology and pathogenesis of the diseases in the farm, which can
manifest themselves in clinical and subclinical forms. In addition, the
determination of the parameters of the metabolic profile should be carried out at
all stages of the production and reproductive cycle of cows, in the dry period, in
the postpartum period and in lactation, and should include a representative
number of animals on the farm. The importance of metabolic profile analysis in
high-yield dairy farms is demonstrated by its advantage over other diagnostic
techniques in assessing and detecting health problems and in evaluating the
intake and utilization of nutrients frommeals. In this way, it is possible to prevent
metabolic and other health problems in high-yielding cows and treat them in a
timely manner, thus maintaining the health of the herd at a high level. From all
this, it can be concluded that metabolic profile analysis directly contributes to
sustainable agricultural production, the most important aspect of which is the
preservation of animal health and the minimization of negative impacts on the
environment.
PB  - Banja Luka : Veterinarska komora Republike Srpske
C3  - 28. Godišnje savjetovanje doktora veterinarske medicine Republike Srpske (Bosna i Hercegovina), Trebinje, 15 - 17. jun 2023
T1  - Značaj analize metaboličkog profila u kontroli zdravlja i održivoj proizvodnji na govedarskim farmama
T1  - The importance of metabolic profile analysis for health control and sustainable production in cattle farms
SP  - 62
EP  - 65
UR  - https://hdl.handle.net/21.15107/rcub_veterinar_2999
ER  - 

@conference{
author = "Nedić, Sreten and Vujanac, Ivan and Prodanović, Radiša and Bojkovski, Jovan and Arsić, Sveta and Bošnjaković, Dušan and Jovanović, Ljubomir and Kirovski, Danijela",
year = "2023",
abstract = "Анализа метаболичког профила представља одређивање биохемијских
параметара крви значајних за процену здравственог статуса и производних
перформанси код високо-млечних крава. Посебан значај анализе
метаболичког профила огледа се у процени искористивости хранљивих
материја оброка код крава у различитим фазама производно репродуктивног
циклуса, односно о њиховом енергетском, протеинском и минералном
статусу. Поред тога, анализа метаболичког профила омогућава нам
правовремено откривање супклиничких и клиничких постпарталних обољења
која су повезана са лактацијом и репродукцијом, што представља приоритет
на савременим фармама високо-млечних крава, јер ти фактори значајно утичу
на рентабилност производње. У рутинској анализи метаболичког профила у
стадима високо-млечних крава одређују се концентрације глукозе,
бетахидроксибутерне киселине (БХБ), укупних протеина, албумина,
калцијума, фосфора, урее, укупног билирубина, триглицерида као и активност
ензима јетре аспартат-аминотрансферазе (АСТ) и гама-глутамилтрансферазе
(ГГТ). Број параметара метаболичког профила зависи од етиологије и
патогенезе обољења на фарми која могу да се испољавају у клиничкој и
супклиничкој форми. Такође, одређивање параметара метаболичког профила
треба да се обави у свим фазама производно-репродуктивног циклуса крава,
засушење, пуерперијум и лактација, као и да се обухвати репрезентативан број
животиња на фарми. Значај анализе метаболичког профила на високо-
млечним фармама огледа се у његовој предности над осталим дијагностичким
процедурама у сагледавању и откривању како здравствених проблема, тако ипроцени снабдевености и искористивости хранљивих материја из оброка. На
тај начин, омогућава се превениција као и благовремена терапија
метаболичких и других здравствених проблема код високом-млечних крава,
чиме се одржава здравље стада на високом нивоу. На основу свега наведеног
може се закључити да анализа метаболичког профила директно доприноси
одрживој фармској производњи, чији је главни аспект очување здравља
животиња и минималан негативан утицај на животну средину., Metabolic profile analysis represents the determination of blood biochemical
parameters important for the assessment of health status and production
performance of high-yielding dairy cows. The particular importance of metabolic
profile analysis is reflected in the evaluation of feed nutrient utilization in cows
at different stages of the production and reproduction cycle, i.e. their energy,
protein and mineral status. In addition, metabolic profile analysis allows timely
detection of subclinical and clinical postpartum diseases related to lactation and
reproduction, which is of primary importance in modern dairy farms, as these
factors significantly affect the profitability of production. Routine analysis of the
metabolic profile in herds of high-yielding dairy cows includes determination of
concentrations of glucose, beta-hydroxybutyric acid (BHB), total proteins,
albumin, calcium, phosphorus, urea, total bilirubin, triglycerides, and activity of
the liver enzymes aspartate aminotransferase (AST) and gamma-
glutamyltransferase (GGT). The number of parameters of the metabolic profile
depends on the etiology and pathogenesis of the diseases in the farm, which can
manifest themselves in clinical and subclinical forms. In addition, the
determination of the parameters of the metabolic profile should be carried out at
all stages of the production and reproductive cycle of cows, in the dry period, in
the postpartum period and in lactation, and should include a representative
number of animals on the farm. The importance of metabolic profile analysis in
high-yield dairy farms is demonstrated by its advantage over other diagnostic
techniques in assessing and detecting health problems and in evaluating the
intake and utilization of nutrients frommeals. In this way, it is possible to prevent
metabolic and other health problems in high-yielding cows and treat them in a
timely manner, thus maintaining the health of the herd at a high level. From all
this, it can be concluded that metabolic profile analysis directly contributes to
sustainable agricultural production, the most important aspect of which is the
preservation of animal health and the minimization of negative impacts on the
environment.",
publisher = "Banja Luka : Veterinarska komora Republike Srpske",
journal = "28. Godišnje savjetovanje doktora veterinarske medicine Republike Srpske (Bosna i Hercegovina), Trebinje, 15 - 17. jun 2023",
title = "Značaj analize metaboličkog profila u kontroli zdravlja i održivoj proizvodnji na govedarskim farmama, The importance of metabolic profile analysis for health control and sustainable production in cattle farms",
pages = "62-65",
url = "https://hdl.handle.net/21.15107/rcub_veterinar_2999"
}

Nedić, S., Vujanac, I., Prodanović, R., Bojkovski, J., Arsić, S., Bošnjaković, D., Jovanović, L.,& Kirovski, D.. (2023). Značaj analize metaboličkog profila u kontroli zdravlja i održivoj proizvodnji na govedarskim farmama. in 28. Godišnje savjetovanje doktora veterinarske medicine Republike Srpske (Bosna i Hercegovina), Trebinje, 15 - 17. jun 2023
Banja Luka : Veterinarska komora Republike Srpske., 62-65.
https://hdl.handle.net/21.15107/rcub_veterinar_2999

Nedić S, Vujanac I, Prodanović R, Bojkovski J, Arsić S, Bošnjaković D, Jovanović L, Kirovski D. Značaj analize metaboličkog profila u kontroli zdravlja i održivoj proizvodnji na govedarskim farmama. in 28. Godišnje savjetovanje doktora veterinarske medicine Republike Srpske (Bosna i Hercegovina), Trebinje, 15 - 17. jun 2023. 2023;:62-65.
https://hdl.handle.net/21.15107/rcub_veterinar_2999 .

Nedić, Sreten, Vujanac, Ivan, Prodanović, Radiša, Bojkovski, Jovan, Arsić, Sveta, Bošnjaković, Dušan, Jovanović, Ljubomir, Kirovski, Danijela, "Značaj analize metaboličkog profila u kontroli zdravlja i održivoj proizvodnji na govedarskim farmama" in 28. Godišnje savjetovanje doktora veterinarske medicine Republike Srpske (Bosna i Hercegovina), Trebinje, 15 - 17. jun 2023 (2023):62-65,
https://hdl.handle.net/21.15107/rcub_veterinar_2999 .

TY  - CONF
AU  - Vujanac, Ivan
AU  - Prodanović, Radiša
AU  - Nedić, Sreten
AU  - Arsić, Sveta
AU  - Jovanović, Ljubomir
AU  - Bošnjaković, Dušan
AU  - Stojković, Milica
AU  - Dražić, Slavica
AU  - Kirovski, Danijela
PY  - 2023
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/3437
AB  - Poslednjih godina se sve više ukazuje na povezanost uzgoja krava i emisije metana sa farmi visokomlečnih krava kao posledice enterične fermentacije koja se odvija u buragu ovih životinja. Savremeni uzgoj visokomlečnih krava ima za
cilj proizvodnju mleka višu od 9 000 litara po kravi u toku jedne laktacije. Takva proizvodnja zahteva značajno povećanje unosa hrane, ali i izmenjene hranidbene uslove u
smislu povećanog udela koncentrovanog dela u obroku za krave. Kod povećanog unosa
hrane, dnevna emisija metana po životinji je povećana, ali je emisija ovog gasa po kilogramu proizvedenog mleka manja. Povećanjem energetske vrednosti obroka, dodavanjem veće količine skroba iz žitarica može da se smanji produkcija metana za 7 do 10
procenata. Međutim, povećanjem sadržaja skroba u koncentrovanom delu obroka za
visokomlečne krave, tokom tranzicionog perioda i rane faze laktacije, može da se poveća rizik za nastanak metaboličkih poremećaja zdravlja kao što su subakutna acidoza
buraga, ketoza i pododermatitis, za koje je dokazano da povećavaju emisiju metana.Takođe je utvrđeno da krave obolele od supkliničkog, odnosno kliničkog mastitisa, emituju više metana u odnosu na zdrave krave. Sprovođenje mera imunoprofilakse posebno
kod bolesti koje ugrožavaju ekonomsku isplativost farmi visokomlečnih krava pokazale
su se kao veoma efikasne u smanjenju emisije gasova sa efektom staklene bašte (engl.
greenhouse gases – GHG). Iz svega navedenog proizilazi, da jedino zdrave krave mogu
da doprinesu održivoj proizvodnji koja uključuje uspostavljanje ekološki prihvatljivog
uzgoja.
PB  - Beograd : Udruženje veterinara praktičara Srbije
C3  - V Simpozijum sa međunarodnim učešćem - Zdravstvena zaštita i reprodukcija papkara, kopitara, živine i mesojeda, Beograd, 17 - 18. mart 2023
T1  - Zdravstveni status i održiva proizvodnja na savremenim farmama visokomlečnih krava
SP  - 3
EP  - 10
UR  - https://hdl.handle.net/21.15107/rcub_veterinar_3437
ER  - 

@conference{
author = "Vujanac, Ivan and Prodanović, Radiša and Nedić, Sreten and Arsić, Sveta and Jovanović, Ljubomir and Bošnjaković, Dušan and Stojković, Milica and Dražić, Slavica and Kirovski, Danijela",
year = "2023",
abstract = "Poslednjih godina se sve više ukazuje na povezanost uzgoja krava i emisije metana sa farmi visokomlečnih krava kao posledice enterične fermentacije koja se odvija u buragu ovih životinja. Savremeni uzgoj visokomlečnih krava ima za
cilj proizvodnju mleka višu od 9 000 litara po kravi u toku jedne laktacije. Takva proizvodnja zahteva značajno povećanje unosa hrane, ali i izmenjene hranidbene uslove u
smislu povećanog udela koncentrovanog dela u obroku za krave. Kod povećanog unosa
hrane, dnevna emisija metana po životinji je povećana, ali je emisija ovog gasa po kilogramu proizvedenog mleka manja. Povećanjem energetske vrednosti obroka, dodavanjem veće količine skroba iz žitarica može da se smanji produkcija metana za 7 do 10
procenata. Međutim, povećanjem sadržaja skroba u koncentrovanom delu obroka za
visokomlečne krave, tokom tranzicionog perioda i rane faze laktacije, može da se poveća rizik za nastanak metaboličkih poremećaja zdravlja kao što su subakutna acidoza
buraga, ketoza i pododermatitis, za koje je dokazano da povećavaju emisiju metana.Takođe je utvrđeno da krave obolele od supkliničkog, odnosno kliničkog mastitisa, emituju više metana u odnosu na zdrave krave. Sprovođenje mera imunoprofilakse posebno
kod bolesti koje ugrožavaju ekonomsku isplativost farmi visokomlečnih krava pokazale
su se kao veoma efikasne u smanjenju emisije gasova sa efektom staklene bašte (engl.
greenhouse gases – GHG). Iz svega navedenog proizilazi, da jedino zdrave krave mogu
da doprinesu održivoj proizvodnji koja uključuje uspostavljanje ekološki prihvatljivog
uzgoja.",
publisher = "Beograd : Udruženje veterinara praktičara Srbije",
journal = "V Simpozijum sa međunarodnim učešćem - Zdravstvena zaštita i reprodukcija papkara, kopitara, živine i mesojeda, Beograd, 17 - 18. mart 2023",
title = "Zdravstveni status i održiva proizvodnja na savremenim farmama visokomlečnih krava",
pages = "3-10",
url = "https://hdl.handle.net/21.15107/rcub_veterinar_3437"
}

Vujanac, I., Prodanović, R., Nedić, S., Arsić, S., Jovanović, L., Bošnjaković, D., Stojković, M., Dražić, S.,& Kirovski, D.. (2023). Zdravstveni status i održiva proizvodnja na savremenim farmama visokomlečnih krava. in V Simpozijum sa međunarodnim učešćem - Zdravstvena zaštita i reprodukcija papkara, kopitara, živine i mesojeda, Beograd, 17 - 18. mart 2023
Beograd : Udruženje veterinara praktičara Srbije., 3-10.
https://hdl.handle.net/21.15107/rcub_veterinar_3437

Vujanac I, Prodanović R, Nedić S, Arsić S, Jovanović L, Bošnjaković D, Stojković M, Dražić S, Kirovski D. Zdravstveni status i održiva proizvodnja na savremenim farmama visokomlečnih krava. in V Simpozijum sa međunarodnim učešćem - Zdravstvena zaštita i reprodukcija papkara, kopitara, živine i mesojeda, Beograd, 17 - 18. mart 2023. 2023;:3-10.
https://hdl.handle.net/21.15107/rcub_veterinar_3437 .

Vujanac, Ivan, Prodanović, Radiša, Nedić, Sreten, Arsić, Sveta, Jovanović, Ljubomir, Bošnjaković, Dušan, Stojković, Milica, Dražić, Slavica, Kirovski, Danijela, "Zdravstveni status i održiva proizvodnja na savremenim farmama visokomlečnih krava" in V Simpozijum sa međunarodnim učešćem - Zdravstvena zaštita i reprodukcija papkara, kopitara, živine i mesojeda, Beograd, 17 - 18. mart 2023 (2023):3-10,
https://hdl.handle.net/21.15107/rcub_veterinar_3437 .

TY  - CONF
AU  - Bojkovski, Jovan
AU  - Relić, Renata
AU  - Đurić, Miloje
AU  - Arsić, Sveta
AU  - Nedić, Sreten
AU  - Prodanović, Radiša
AU  - Mitrović, Aleksandara
AU  - Pavlović, Ivan
AU  - Dobrosavljević, Ivan
AU  - Angelovski, Branko
AU  - Becskei, Zsolt
PY  - 2023
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/3381
PB  - University of Agricultural Sciences and Veterinary Medicine of Cluj-Napoca
C3  - 22nd International Conference Life sciences for sustainable development, Cluj-Napoca, Romania, 28th– 30th September, 2023
T1  - Assessment of biosecurity on the dairy farm
SP  - 298
EP  - 298
UR  - https://hdl.handle.net/21.15107/rcub_veterinar_3381
ER  - 

@conference{
author = "Bojkovski, Jovan and Relić, Renata and Đurić, Miloje and Arsić, Sveta and Nedić, Sreten and Prodanović, Radiša and Mitrović, Aleksandara and Pavlović, Ivan and Dobrosavljević, Ivan and Angelovski, Branko and Becskei, Zsolt",
year = "2023",
publisher = "University of Agricultural Sciences and Veterinary Medicine of Cluj-Napoca",
journal = "22nd International Conference Life sciences for sustainable development, Cluj-Napoca, Romania, 28th– 30th September, 2023",
title = "Assessment of biosecurity on the dairy farm",
pages = "298-298",
url = "https://hdl.handle.net/21.15107/rcub_veterinar_3381"
}

Bojkovski, J., Relić, R., Đurić, M., Arsić, S., Nedić, S., Prodanović, R., Mitrović, A., Pavlović, I., Dobrosavljević, I., Angelovski, B.,& Becskei, Z.. (2023). Assessment of biosecurity on the dairy farm. in 22nd International Conference Life sciences for sustainable development, Cluj-Napoca, Romania, 28th– 30th September, 2023
University of Agricultural Sciences and Veterinary Medicine of Cluj-Napoca., 298-298.
https://hdl.handle.net/21.15107/rcub_veterinar_3381

Bojkovski J, Relić R, Đurić M, Arsić S, Nedić S, Prodanović R, Mitrović A, Pavlović I, Dobrosavljević I, Angelovski B, Becskei Z. Assessment of biosecurity on the dairy farm. in 22nd International Conference Life sciences for sustainable development, Cluj-Napoca, Romania, 28th– 30th September, 2023. 2023;:298-298.
https://hdl.handle.net/21.15107/rcub_veterinar_3381 .

Bojkovski, Jovan, Relić, Renata, Đurić, Miloje, Arsić, Sveta, Nedić, Sreten, Prodanović, Radiša, Mitrović, Aleksandara, Pavlović, Ivan, Dobrosavljević, Ivan, Angelovski, Branko, Becskei, Zsolt, "Assessment of biosecurity on the dairy farm" in 22nd International Conference Life sciences for sustainable development, Cluj-Napoca, Romania, 28th– 30th September, 2023 (2023):298-298,
https://hdl.handle.net/21.15107/rcub_veterinar_3381 .

TY  - JOUR
AU  - Bojkovski, Jovan
AU  - Prodanov-Radulović, Jasna
AU  - Nedić, Sreten
AU  - Arsić, Sveta
AU  - Đurić, Miloje
AU  - Mitrović, Aleksandra
AU  - Žutić, Jadranka
AU  - Kureljušić, Jasna
AU  - Pavlović, Ivan
AU  - Zdravković, Nemanja
AU  - Kureljušić, Branislav
AU  - Angjelovski, Branko
AU  - Aniţă, Dragoş Constantin
AU  - Olsbanu, Luanda
AU  - Anita, Adriana Elena
AU  - Prodanović, Radiša
PY  - 2023
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/3495
AB  - Mycopasmatic or enzootic pneumonia is the most common disease of the respiratory system under in the intensive pig
production. It is clinically manifested by coughing, a chronic inflammatory process in the lungs, high morbidity and a
relatively low percentage of deaths. The infection can be transmitted horizontally and vertically. Mycoplasma
hyopneumoniae invades the epithelial cells of the trachea, bronchi, bronchioles and alveoli and disrupts the function of
the ciliary body. Evagination of epithelial cells occurs, so that the cleansing of the airway mucosa by the mucociliary
apparatus is inhibited. As a result, bacterial complications (Pasteurella, Bordetella, Klebsiella, Actinobacillus,
Hemophilus) are common.M.hyopneminia can play imortant role in PRDC. The development of Mycoplasma
hyopneumoniae is favoured by large congregations of pigs in small spaces, inadequate environmental conditions
(microclimate), parasitic infections and inadequate nutrition. Mycoplasma hyopneumonia can be a significant health
problem on the fattening farm, exacerbated by the influence of non-specific factors as well as the spread of other
bacterial pathogens.
PB  - Iasi : Ion Ionescu de la Brad
T2  - Scientific papers - Veterinary Medicine
T1  - Mycoplasmatic (enzootic) pneumonia of pigs as a health problem in fattening units
VL  - 66
IS  - 3
SP  - 35
EP  - 43
UR  - https://hdl.handle.net/21.15107/rcub_veterinar_3495
ER  - 

@article{
author = "Bojkovski, Jovan and Prodanov-Radulović, Jasna and Nedić, Sreten and Arsić, Sveta and Đurić, Miloje and Mitrović, Aleksandra and Žutić, Jadranka and Kureljušić, Jasna and Pavlović, Ivan and Zdravković, Nemanja and Kureljušić, Branislav and Angjelovski, Branko and Aniţă, Dragoş Constantin and Olsbanu, Luanda and Anita, Adriana Elena and Prodanović, Radiša",
year = "2023",
abstract = "Mycopasmatic or enzootic pneumonia is the most common disease of the respiratory system under in the intensive pig
production. It is clinically manifested by coughing, a chronic inflammatory process in the lungs, high morbidity and a
relatively low percentage of deaths. The infection can be transmitted horizontally and vertically. Mycoplasma
hyopneumoniae invades the epithelial cells of the trachea, bronchi, bronchioles and alveoli and disrupts the function of
the ciliary body. Evagination of epithelial cells occurs, so that the cleansing of the airway mucosa by the mucociliary
apparatus is inhibited. As a result, bacterial complications (Pasteurella, Bordetella, Klebsiella, Actinobacillus,
Hemophilus) are common.M.hyopneminia can play imortant role in PRDC. The development of Mycoplasma
hyopneumoniae is favoured by large congregations of pigs in small spaces, inadequate environmental conditions
(microclimate), parasitic infections and inadequate nutrition. Mycoplasma hyopneumonia can be a significant health
problem on the fattening farm, exacerbated by the influence of non-specific factors as well as the spread of other
bacterial pathogens.",
publisher = "Iasi : Ion Ionescu de la Brad",
journal = "Scientific papers - Veterinary Medicine",
title = "Mycoplasmatic (enzootic) pneumonia of pigs as a health problem in fattening units",
volume = "66",
number = "3",
pages = "35-43",
url = "https://hdl.handle.net/21.15107/rcub_veterinar_3495"
}

Bojkovski, J., Prodanov-Radulović, J., Nedić, S., Arsić, S., Đurić, M., Mitrović, A., Žutić, J., Kureljušić, J., Pavlović, I., Zdravković, N., Kureljušić, B., Angjelovski, B., Aniţă, D. C., Olsbanu, L., Anita, A. E.,& Prodanović, R.. (2023). Mycoplasmatic (enzootic) pneumonia of pigs as a health problem in fattening units. in Scientific papers - Veterinary Medicine
Iasi : Ion Ionescu de la Brad., 66(3), 35-43.
https://hdl.handle.net/21.15107/rcub_veterinar_3495

Bojkovski J, Prodanov-Radulović J, Nedić S, Arsić S, Đurić M, Mitrović A, Žutić J, Kureljušić J, Pavlović I, Zdravković N, Kureljušić B, Angjelovski B, Aniţă DC, Olsbanu L, Anita AE, Prodanović R. Mycoplasmatic (enzootic) pneumonia of pigs as a health problem in fattening units. in Scientific papers - Veterinary Medicine. 2023;66(3):35-43.
https://hdl.handle.net/21.15107/rcub_veterinar_3495 .

Bojkovski, Jovan, Prodanov-Radulović, Jasna, Nedić, Sreten, Arsić, Sveta, Đurić, Miloje, Mitrović, Aleksandra, Žutić, Jadranka, Kureljušić, Jasna, Pavlović, Ivan, Zdravković, Nemanja, Kureljušić, Branislav, Angjelovski, Branko, Aniţă, Dragoş Constantin, Olsbanu, Luanda, Anita, Adriana Elena, Prodanović, Radiša, "Mycoplasmatic (enzootic) pneumonia of pigs as a health problem in fattening units" in Scientific papers - Veterinary Medicine, 66, no. 3 (2023):35-43,
https://hdl.handle.net/21.15107/rcub_veterinar_3495 .

TY  - CONF
AU  - Bojkovski, Jovan
AU  - Nedić, Sreten
AU  - Arsić, Sveta
AU  - Vujanac, Ivan
AU  - Prodanović, Radiša
AU  - Mitrović, Aleksandra
AU  - Bugarski, Dejan
AU  - Panousis, Nikolaos K.
AU  - Kalaitzakis, Emmanouil
AU  - Ninković, Milan
PY  - 2023
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/3073
AB  - Хромост је најранији, али и најважнији клинички симптом обољења
акроподијума говеда. Према литературним подацима у 90 % случајева узрок
хромости је локализован у папцима, а у 10 % случајеваје у другим анатомским
деловима екстремитета. Патолошки процес је у 88 % случајева испољен на
задњим екстремитетима. Ламинитис представља асептично запаљење
коријума папака. Као узроци настанка овог обољења поред механичког
преоптерећења папака наводе се и токсични узроци. Дуже давање лако
сварљиве концентроване хране, стварање ацидозе у бурагу, нагла промена
хране, посебно исхрана зеленим јечмом, овсем, свеже покошеним младим
легуминозама и исхрана плеснивом храном, могу довести до појаве
ламинитиса. Ламинитис је често резултат утицаја великог броја чиниоца, као
што су метаболички и дигестивни поремећаји, порођај стрес, маститис,
метритис, дислокација сиришта, лежиште без или са врло мало простирке,
немогућност кретања, прегојеност и лош менаџмент исхране. Оброк који
доводи до ацидозе, доводи и до ламинитиса, врло је тежак за корекцију када се
највећи проценат хранива у оброку састоји од угљено хидратних материја.
Сматра се да вазоактивне материје (хистамин) које улазе у крвоток из бурага
доводе до оштећења коријума папака. Метаболички поремећај настаје услед
ниског pH садржаја бурага и ланчано долази до патофизиолошких поремећаја
који на крају резултирају исхемијом коријума папака и клинички
манифестним ламинитисом (одлагањем ногу због бола, а понекад и принудног
лежања). Верује се да осим хистамина и бактеријски ендотоксини, млечна
киселина и друге биолошки активне материје доприносе настанку овог обољења. Примена основних принципа исхране музних крава могу
превенирати појаву ламинитиса самим тим и појаву економских губитака
услед хромости.
AB  - Lameness is the earliest, but also the most important clinical symptom of
acropodium disease in cattle. According to literature data, in 90% of cases the
cause of lameness is localized in the ankles, and in 10% of cases it is in other
anatomical parts of the extremities. In 88% of cases, the pathological process is
manifested in the hind limbs. Laminitis is an aseptic inflammation of the corium
of toe. In addition to mechanical overloading of the toe, toxic causes are cited as
the causes of this disease. Prolonged administration of easily digestible
concentrated food, creation of acidosis in the rumen, sudden change of food,
especially feeding on green barley, oats, freshly cut young legumes and feeding on
moldy food, can lead to the appearance of laminitis. Laminitis is often the result
of the influence of a large number of factors, such as metabolic and digestive
disorders, childbirth stress, mastitis, metritis, dislocation of the abomazus, bed
without or with very little mat, inability to move, obesity and poor nutrition
management. A meal that leads to acidosis also leads to laminitis, it is very
difficult to correct when the largest percentage of nutrients in the meal consists
of carbohydrates. It is believed that vasoactive substances (histamine) entering
the bloodstream from the rumen lead to damage to the corium of the papilla. The
metabolic disorder is caused by the low pH content of the rumen and leads to
pathophysiological disorders in a chain, which ultimately result in ischemia of the
corium of the toe and clinically manifest laminitis (postponement of the legs due
to pain, and sometimes forced lying down). It is believed that, in addition to
histamine, bacterial endotoxins, lactic acid and others biologically active substances contribute to the development of this disease. The application of the
basic principles of feeding dairy cows can prevent the occurrence of laminitis and
thus the occurrence of economic losses due to lameness.
PB  - Banja Luka : Veterinarska komora Republike Srpske
C3  - 28. Godišnje savjetovanje doktora veterinarske medicine Republike Srpske (Bosna i Hercegovina), Trebinje, 15 - 17. jun 2023
T1  - Patogeneza laminitisa mlečnih krava
T1  - Pathogenisis of laminits in dairy cows
SP  - 71
EP  - 74
UR  - https://hdl.handle.net/21.15107/rcub_veterinar_3073
ER  - 

@conference{
author = "Bojkovski, Jovan and Nedić, Sreten and Arsić, Sveta and Vujanac, Ivan and Prodanović, Radiša and Mitrović, Aleksandra and Bugarski, Dejan and Panousis, Nikolaos K. and Kalaitzakis, Emmanouil and Ninković, Milan",
year = "2023",
abstract = "Хромост је најранији, али и најважнији клинички симптом обољења
акроподијума говеда. Према литературним подацима у 90 % случајева узрок
хромости је локализован у папцима, а у 10 % случајеваје у другим анатомским
деловима екстремитета. Патолошки процес је у 88 % случајева испољен на
задњим екстремитетима. Ламинитис представља асептично запаљење
коријума папака. Као узроци настанка овог обољења поред механичког
преоптерећења папака наводе се и токсични узроци. Дуже давање лако
сварљиве концентроване хране, стварање ацидозе у бурагу, нагла промена
хране, посебно исхрана зеленим јечмом, овсем, свеже покошеним младим
легуминозама и исхрана плеснивом храном, могу довести до појаве
ламинитиса. Ламинитис је често резултат утицаја великог броја чиниоца, као
што су метаболички и дигестивни поремећаји, порођај стрес, маститис,
метритис, дислокација сиришта, лежиште без или са врло мало простирке,
немогућност кретања, прегојеност и лош менаџмент исхране. Оброк који
доводи до ацидозе, доводи и до ламинитиса, врло је тежак за корекцију када се
највећи проценат хранива у оброку састоји од угљено хидратних материја.
Сматра се да вазоактивне материје (хистамин) које улазе у крвоток из бурага
доводе до оштећења коријума папака. Метаболички поремећај настаје услед
ниског pH садржаја бурага и ланчано долази до патофизиолошких поремећаја
који на крају резултирају исхемијом коријума папака и клинички
манифестним ламинитисом (одлагањем ногу због бола, а понекад и принудног
лежања). Верује се да осим хистамина и бактеријски ендотоксини, млечна
киселина и друге биолошки активне материје доприносе настанку овог обољења. Примена основних принципа исхране музних крава могу
превенирати појаву ламинитиса самим тим и појаву економских губитака
услед хромости., Lameness is the earliest, but also the most important clinical symptom of
acropodium disease in cattle. According to literature data, in 90% of cases the
cause of lameness is localized in the ankles, and in 10% of cases it is in other
anatomical parts of the extremities. In 88% of cases, the pathological process is
manifested in the hind limbs. Laminitis is an aseptic inflammation of the corium
of toe. In addition to mechanical overloading of the toe, toxic causes are cited as
the causes of this disease. Prolonged administration of easily digestible
concentrated food, creation of acidosis in the rumen, sudden change of food,
especially feeding on green barley, oats, freshly cut young legumes and feeding on
moldy food, can lead to the appearance of laminitis. Laminitis is often the result
of the influence of a large number of factors, such as metabolic and digestive
disorders, childbirth stress, mastitis, metritis, dislocation of the abomazus, bed
without or with very little mat, inability to move, obesity and poor nutrition
management. A meal that leads to acidosis also leads to laminitis, it is very
difficult to correct when the largest percentage of nutrients in the meal consists
of carbohydrates. It is believed that vasoactive substances (histamine) entering
the bloodstream from the rumen lead to damage to the corium of the papilla. The
metabolic disorder is caused by the low pH content of the rumen and leads to
pathophysiological disorders in a chain, which ultimately result in ischemia of the
corium of the toe and clinically manifest laminitis (postponement of the legs due
to pain, and sometimes forced lying down). It is believed that, in addition to
histamine, bacterial endotoxins, lactic acid and others biologically active substances contribute to the development of this disease. The application of the
basic principles of feeding dairy cows can prevent the occurrence of laminitis and
thus the occurrence of economic losses due to lameness.",
publisher = "Banja Luka : Veterinarska komora Republike Srpske",
journal = "28. Godišnje savjetovanje doktora veterinarske medicine Republike Srpske (Bosna i Hercegovina), Trebinje, 15 - 17. jun 2023",
title = "Patogeneza laminitisa mlečnih krava, Pathogenisis of laminits in dairy cows",
pages = "71-74",
url = "https://hdl.handle.net/21.15107/rcub_veterinar_3073"
}

Bojkovski, J., Nedić, S., Arsić, S., Vujanac, I., Prodanović, R., Mitrović, A., Bugarski, D., Panousis, N. K., Kalaitzakis, E.,& Ninković, M.. (2023). Patogeneza laminitisa mlečnih krava. in 28. Godišnje savjetovanje doktora veterinarske medicine Republike Srpske (Bosna i Hercegovina), Trebinje, 15 - 17. jun 2023
Banja Luka : Veterinarska komora Republike Srpske., 71-74.
https://hdl.handle.net/21.15107/rcub_veterinar_3073

Bojkovski J, Nedić S, Arsić S, Vujanac I, Prodanović R, Mitrović A, Bugarski D, Panousis NK, Kalaitzakis E, Ninković M. Patogeneza laminitisa mlečnih krava. in 28. Godišnje savjetovanje doktora veterinarske medicine Republike Srpske (Bosna i Hercegovina), Trebinje, 15 - 17. jun 2023. 2023;:71-74.
https://hdl.handle.net/21.15107/rcub_veterinar_3073 .

Bojkovski, Jovan, Nedić, Sreten, Arsić, Sveta, Vujanac, Ivan, Prodanović, Radiša, Mitrović, Aleksandra, Bugarski, Dejan, Panousis, Nikolaos K., Kalaitzakis, Emmanouil, Ninković, Milan, "Patogeneza laminitisa mlečnih krava" in 28. Godišnje savjetovanje doktora veterinarske medicine Republike Srpske (Bosna i Hercegovina), Trebinje, 15 - 17. jun 2023 (2023):71-74,
https://hdl.handle.net/21.15107/rcub_veterinar_3073 .

TY  - CONF
AU  - Bojkovski, Jovan
AU  - Kureljušić, Branislav
AU  - Nedić, Sreten
AU  - Arsić, Sveta
AU  - Prodanović, Radiša
AU  - Vujanac, Ivan
AU  - Mitrović, Aleksandra
AU  - Pavlović, Ivan
AU  - Dobrosavljević, Ivan
AU  - Angjelovski, Branko
AU  - Prodanov-Radulović, Jasna
AU  - Relić, Renata
PY  - 2023
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/3105
AB  - Bolesti jetre kod svinja su prisutne i ispoljavaju se u velikim aglomeracijama. Prema literaturnim
podacima kao uzroci oboljenja jetre se smatra jednolična i deficitarna ishrana, alimentarni i
bakterijski toksini , parazitke infekcije i neadekvatni zoohigijenski uslovi. Promene na jetri ne
ispoljavaju vidljive kliničke simptome. U postavljanju dijagnoze koristi se analiza biohemisjkih
parametarta. U ovom predavanju smo izložili rezultate biohemuisjske anlize nerastova koji se
koriste u repordukciji sa komercijalnih farmi. Koristili smo sledeće parametre: fosfor, ukupne
proteine, urea, kreatinin, AST. Statiststički značajne razlike su ustanovljene kod sledećih
parametara: fosfor, ukupni proteini, urea i AST. Cilj ovog predavanja je da ukaže na značajnost
biohemijskih paramtera jetre u zdravtvenoj zaštiti svinja.
PB  - Požarevac : Sitograf RM
C3  - 20. Simpozijum Zdravstvena zaštita, selekcija i reprodukcija svinja, Srebrno jezero, 8 - 9. jun 2023
T1  - Bolesti jetre svinja u intenzivnom uzgoju
SP  - 111
EP  - 114
UR  - https://hdl.handle.net/21.15107/rcub_veterinar_3105
ER  - 

@conference{
author = "Bojkovski, Jovan and Kureljušić, Branislav and Nedić, Sreten and Arsić, Sveta and Prodanović, Radiša and Vujanac, Ivan and Mitrović, Aleksandra and Pavlović, Ivan and Dobrosavljević, Ivan and Angjelovski, Branko and Prodanov-Radulović, Jasna and Relić, Renata",
year = "2023",
abstract = "Bolesti jetre kod svinja su prisutne i ispoljavaju se u velikim aglomeracijama. Prema literaturnim
podacima kao uzroci oboljenja jetre se smatra jednolična i deficitarna ishrana, alimentarni i
bakterijski toksini , parazitke infekcije i neadekvatni zoohigijenski uslovi. Promene na jetri ne
ispoljavaju vidljive kliničke simptome. U postavljanju dijagnoze koristi se analiza biohemisjkih
parametarta. U ovom predavanju smo izložili rezultate biohemuisjske anlize nerastova koji se
koriste u repordukciji sa komercijalnih farmi. Koristili smo sledeće parametre: fosfor, ukupne
proteine, urea, kreatinin, AST. Statiststički značajne razlike su ustanovljene kod sledećih
parametara: fosfor, ukupni proteini, urea i AST. Cilj ovog predavanja je da ukaže na značajnost
biohemijskih paramtera jetre u zdravtvenoj zaštiti svinja.",
publisher = "Požarevac : Sitograf RM",
journal = "20. Simpozijum Zdravstvena zaštita, selekcija i reprodukcija svinja, Srebrno jezero, 8 - 9. jun 2023",
title = "Bolesti jetre svinja u intenzivnom uzgoju",
pages = "111-114",
url = "https://hdl.handle.net/21.15107/rcub_veterinar_3105"
}

Bojkovski, J., Kureljušić, B., Nedić, S., Arsić, S., Prodanović, R., Vujanac, I., Mitrović, A., Pavlović, I., Dobrosavljević, I., Angjelovski, B., Prodanov-Radulović, J.,& Relić, R.. (2023). Bolesti jetre svinja u intenzivnom uzgoju. in 20. Simpozijum Zdravstvena zaštita, selekcija i reprodukcija svinja, Srebrno jezero, 8 - 9. jun 2023
Požarevac : Sitograf RM., 111-114.
https://hdl.handle.net/21.15107/rcub_veterinar_3105

Bojkovski J, Kureljušić B, Nedić S, Arsić S, Prodanović R, Vujanac I, Mitrović A, Pavlović I, Dobrosavljević I, Angjelovski B, Prodanov-Radulović J, Relić R. Bolesti jetre svinja u intenzivnom uzgoju. in 20. Simpozijum Zdravstvena zaštita, selekcija i reprodukcija svinja, Srebrno jezero, 8 - 9. jun 2023. 2023;:111-114.
https://hdl.handle.net/21.15107/rcub_veterinar_3105 .

Bojkovski, Jovan, Kureljušić, Branislav, Nedić, Sreten, Arsić, Sveta, Prodanović, Radiša, Vujanac, Ivan, Mitrović, Aleksandra, Pavlović, Ivan, Dobrosavljević, Ivan, Angjelovski, Branko, Prodanov-Radulović, Jasna, Relić, Renata, "Bolesti jetre svinja u intenzivnom uzgoju" in 20. Simpozijum Zdravstvena zaštita, selekcija i reprodukcija svinja, Srebrno jezero, 8 - 9. jun 2023 (2023):111-114,
https://hdl.handle.net/21.15107/rcub_veterinar_3105 .

TY  - CONF
AU  - Nedić, Sreten
AU  - Prodanović, Radiša
AU  - Bojkovski, Jovan
AU  - Arsić, Sveta
AU  - Vujanac, Ivan
PY  - 2023
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/3099
AB  - Sindrom ležeće krave predstavlja nemogućnost ustajanja kod visoko
gravidnih krava ili krava u ranom puerperijumu, koje traje duže
od 24 časa. Životinje leže oslonjenje na sternum, uz očuvanu sposobnost
da unose hranu i vodu, pri čemu svest može biti narušena. Etiologija
nastanka ovog oboljenja je kompleksna i uključuje više faktora
kao što su traumatski, metabolički, neurološki ili infektivni. Iz tog razloga,
lista diferencijalnih dijagnoza ovog oboljenja je velika, a najčešće
pominjani su distokija, masna jetra, ketoza, hipofosfatemija, septični
mastitis, peritonitis kao i desna dislokacija sirišta. Bez obzira na primarni
uzrok ležanja, kod svih obolelih goveda kao posledica nemogućnosti
ustajanja dolazi do sekundarnog oštećenja mišića i nerava
kao posledica njihove kompresije i/ili pritiska usled ležanja na čvrstoj
podlozi. U zavisnosti od stepena oštećenja mišića i nerava zavisiće
i ishod terapije kao i oporavak krava obolelih od sindroma ležanja.
Iz tog razloga, pored detaljnog kliničkog pregleda, a u cilju utvrđivanja
pouzdanosti i opravdanosti lečenja obolelih životinja, potrebno je
sprovoditi dijagnostičke testove. Najznačajniji biohemijski parametri
koji nam služe za procenu stepena oštećenja i uspeha oporavka krava
obolelih od sindoma ležanja su koncentracije Ca, P, Mg i K, kao i
aktivnost enzima AST, LDH i CK.
PB  - Beograd : Fakultet veterinarske medicine, Centar za izdavačku delatnost i promet učila
C3  - XLIV seminar za inovacije znanja veterinara, Beograd, 24. februar 2023
T1  - Diferencijalna dijagnostika sindroma ležeće krave
VL  - 135
EP  - 143
UR  - https://hdl.handle.net/21.15107/rcub_veterinar_3099
ER  - 

@conference{
author = "Nedić, Sreten and Prodanović, Radiša and Bojkovski, Jovan and Arsić, Sveta and Vujanac, Ivan",
year = "2023",
abstract = "Sindrom ležeće krave predstavlja nemogućnost ustajanja kod visoko
gravidnih krava ili krava u ranom puerperijumu, koje traje duže
od 24 časa. Životinje leže oslonjenje na sternum, uz očuvanu sposobnost
da unose hranu i vodu, pri čemu svest može biti narušena. Etiologija
nastanka ovog oboljenja je kompleksna i uključuje više faktora
kao što su traumatski, metabolički, neurološki ili infektivni. Iz tog razloga,
lista diferencijalnih dijagnoza ovog oboljenja je velika, a najčešće
pominjani su distokija, masna jetra, ketoza, hipofosfatemija, septični
mastitis, peritonitis kao i desna dislokacija sirišta. Bez obzira na primarni
uzrok ležanja, kod svih obolelih goveda kao posledica nemogućnosti
ustajanja dolazi do sekundarnog oštećenja mišića i nerava
kao posledica njihove kompresije i/ili pritiska usled ležanja na čvrstoj
podlozi. U zavisnosti od stepena oštećenja mišića i nerava zavisiće
i ishod terapije kao i oporavak krava obolelih od sindroma ležanja.
Iz tog razloga, pored detaljnog kliničkog pregleda, a u cilju utvrđivanja
pouzdanosti i opravdanosti lečenja obolelih životinja, potrebno je
sprovoditi dijagnostičke testove. Najznačajniji biohemijski parametri
koji nam služe za procenu stepena oštećenja i uspeha oporavka krava
obolelih od sindoma ležanja su koncentracije Ca, P, Mg i K, kao i
aktivnost enzima AST, LDH i CK.",
publisher = "Beograd : Fakultet veterinarske medicine, Centar za izdavačku delatnost i promet učila",
journal = "XLIV seminar za inovacije znanja veterinara, Beograd, 24. februar 2023",
title = "Diferencijalna dijagnostika sindroma ležeće krave",
volume = "135",
pages = "143",
url = "https://hdl.handle.net/21.15107/rcub_veterinar_3099"
}

Nedić, S., Prodanović, R., Bojkovski, J., Arsić, S.,& Vujanac, I.. (2023). Diferencijalna dijagnostika sindroma ležeće krave. in XLIV seminar za inovacije znanja veterinara, Beograd, 24. februar 2023
Beograd : Fakultet veterinarske medicine, Centar za izdavačku delatnost i promet učila., 135.
https://hdl.handle.net/21.15107/rcub_veterinar_3099

Nedić S, Prodanović R, Bojkovski J, Arsić S, Vujanac I. Diferencijalna dijagnostika sindroma ležeće krave. in XLIV seminar za inovacije znanja veterinara, Beograd, 24. februar 2023. 2023;135:null-143.
https://hdl.handle.net/21.15107/rcub_veterinar_3099 .

Nedić, Sreten, Prodanović, Radiša, Bojkovski, Jovan, Arsić, Sveta, Vujanac, Ivan, "Diferencijalna dijagnostika sindroma ležeće krave" in XLIV seminar za inovacije znanja veterinara, Beograd, 24. februar 2023, 135 (2023),
https://hdl.handle.net/21.15107/rcub_veterinar_3099 .

TY  - JOUR
AU  - Angjelovski, Branko
AU  - Orenga, Clara Marin
AU  - Janevski, Aleksandar
AU  - Dodovski, Aleksandar
AU  - Prodanović, Radiša
AU  - Bojkovski, Jovan
PY  - 2023
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/2944
AB  - Mycoplasma hyopneumoniae (Mhyo) is primary pathogen involved in porcine respiratory diseases complex (PRDC). The
objective of this study was to evaluate Mycoplasma hyopneumoniae (Mhyo) infection in five commercial pig farms by using
serology and lung lesion scoring at slaughter. Five Macedonian pig herds with a history of respiratory diseases were included
in the study. Blood samples were taken from pigs at 6, 10, 14, 18, and 22 weeks of age. Ten animals per age group from each
farm were sampled and tested for antibodies to Mhyo. At abattoir, 50 lungs per farm were scored for lesions associated with
enzootic pneumonia (EP). All farms were seropositive to Mhyo. Higher seroprevalence to Mhyo was observed in grower and
finisher pigs, while significant difference (p<0.001) was detected among farms in 10-, 14-, and 22-week-old pigs. Enzootic
pneumonia-like lesions were detected in 91.2% of all tested lungs with range of 82 to 98% on farm level. Mean lung lesion
score (LLS) obtained for all farms was 11.5 (8.04–14.4). Significant difference for LLS and significantly higher percentage
of severe LLS grade (>10) were found among some of the farms (p<0.001). In conclusion, high seroprevalence to Mhyo in
finishing pigs in most of the farms was most likely due to vaccination. Farms with higher seroprevalence to Mhyo obtained
lower LLS. Serology monitoring of different pig categories and lung assessment at slaughterhouse is a practical tool for
assessing vaccine efficacy of Mhyo in pig farms.
PB  - Saints Cyril and Methodius University of Skopje
T2  - Macedonian Veterinary Review
T1  - Profiling Mycoplasma hyopneumoniae Infection in Commercial Pig Farms Using Serology and Lung Lesions Assessment
DO  - 10.2478/macvetrev-2023-0018
ER  - 

@article{
author = "Angjelovski, Branko and Orenga, Clara Marin and Janevski, Aleksandar and Dodovski, Aleksandar and Prodanović, Radiša and Bojkovski, Jovan",
year = "2023",
abstract = "Mycoplasma hyopneumoniae (Mhyo) is primary pathogen involved in porcine respiratory diseases complex (PRDC). The
objective of this study was to evaluate Mycoplasma hyopneumoniae (Mhyo) infection in five commercial pig farms by using
serology and lung lesion scoring at slaughter. Five Macedonian pig herds with a history of respiratory diseases were included
in the study. Blood samples were taken from pigs at 6, 10, 14, 18, and 22 weeks of age. Ten animals per age group from each
farm were sampled and tested for antibodies to Mhyo. At abattoir, 50 lungs per farm were scored for lesions associated with
enzootic pneumonia (EP). All farms were seropositive to Mhyo. Higher seroprevalence to Mhyo was observed in grower and
finisher pigs, while significant difference (p<0.001) was detected among farms in 10-, 14-, and 22-week-old pigs. Enzootic
pneumonia-like lesions were detected in 91.2% of all tested lungs with range of 82 to 98% on farm level. Mean lung lesion
score (LLS) obtained for all farms was 11.5 (8.04–14.4). Significant difference for LLS and significantly higher percentage
of severe LLS grade (>10) were found among some of the farms (p<0.001). In conclusion, high seroprevalence to Mhyo in
finishing pigs in most of the farms was most likely due to vaccination. Farms with higher seroprevalence to Mhyo obtained
lower LLS. Serology monitoring of different pig categories and lung assessment at slaughterhouse is a practical tool for
assessing vaccine efficacy of Mhyo in pig farms.",
publisher = "Saints Cyril and Methodius University of Skopje",
journal = "Macedonian Veterinary Review",
title = "Profiling Mycoplasma hyopneumoniae Infection in Commercial Pig Farms Using Serology and Lung Lesions Assessment",
doi = "10.2478/macvetrev-2023-0018"
}

Angjelovski, B., Orenga, C. M., Janevski, A., Dodovski, A., Prodanović, R.,& Bojkovski, J.. (2023). Profiling Mycoplasma hyopneumoniae Infection in Commercial Pig Farms Using Serology and Lung Lesions Assessment. in Macedonian Veterinary Review
Saints Cyril and Methodius University of Skopje..
https://doi.org/10.2478/macvetrev-2023-0018

Angjelovski B, Orenga CM, Janevski A, Dodovski A, Prodanović R, Bojkovski J. Profiling Mycoplasma hyopneumoniae Infection in Commercial Pig Farms Using Serology and Lung Lesions Assessment. in Macedonian Veterinary Review. 2023;.
doi:10.2478/macvetrev-2023-0018 .

Angjelovski, Branko, Orenga, Clara Marin, Janevski, Aleksandar, Dodovski, Aleksandar, Prodanović, Radiša, Bojkovski, Jovan, "Profiling Mycoplasma hyopneumoniae Infection in Commercial Pig Farms Using Serology and Lung Lesions Assessment" in Macedonian Veterinary Review (2023),
https://doi.org/10.2478/macvetrev-2023-0018 . .

TY  - JOUR
AU  - Glišić, Dimitrije
AU  - Milićević, Vesna
AU  - Krnjaić, Dejan
AU  - Toplak, Ivan
AU  - Prodanović, Radiša
AU  - Gallardo, Carmina
AU  - Radojičić, Sonja
PY  - 2023
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/2947
AB  - This study provides the frst comprehensive report on the molecular characteristics of African swine fever virus (ASFV) variants
in Serbia between 2019 and 2022. Since its frst observation in July 2019, the disease has been found in wild boar and domestic
swine. The study involved the analysis of 95 ASFV-positive samples collected from 12 infected administrative districts in Serbia.
Partial four genomic regions were genetically characterized, including B646L, E183L, B602L, and the intergenic region (IGR)
between the I73R-I329L genes. The results of the study suggest that multiple ASFV strains belonging to genotype II are circulating
in Serbia, as evidenced by the analysis of the IGR between I73R-I329L genes that showed the most diferences. Furthermore,
the phylogenetic analysis of the B602L gene showed three diferent clades within the CVR I group of ASFV strains. Regarding
the IGR, 98.4% were grouped into IGR II, with only one positive sample grouped into the IGR III group. These fndings provide
essential insights into the molecular characteristics of ASFV variants in Serbia and contribute to the knowledge of circulating
strains of ASFV in Europe. However, further research is necessary to gain a better understanding of ASFV spread and evolution
PB  - Springer
T2  - Veterinary Research Communications
T1  - Genetic analysis reveals multiple intergenic region and central variable region in the African swine fever virus variants circulating in Serbia
VL  - 47
IS  - 4
SP  - 1925
EP  - 1936
DO  - 10.1007/s11259-023-10145-7
ER  - 

@article{
author = "Glišić, Dimitrije and Milićević, Vesna and Krnjaić, Dejan and Toplak, Ivan and Prodanović, Radiša and Gallardo, Carmina and Radojičić, Sonja",
year = "2023",
abstract = "This study provides the frst comprehensive report on the molecular characteristics of African swine fever virus (ASFV) variants
in Serbia between 2019 and 2022. Since its frst observation in July 2019, the disease has been found in wild boar and domestic
swine. The study involved the analysis of 95 ASFV-positive samples collected from 12 infected administrative districts in Serbia.
Partial four genomic regions were genetically characterized, including B646L, E183L, B602L, and the intergenic region (IGR)
between the I73R-I329L genes. The results of the study suggest that multiple ASFV strains belonging to genotype II are circulating
in Serbia, as evidenced by the analysis of the IGR between I73R-I329L genes that showed the most diferences. Furthermore,
the phylogenetic analysis of the B602L gene showed three diferent clades within the CVR I group of ASFV strains. Regarding
the IGR, 98.4% were grouped into IGR II, with only one positive sample grouped into the IGR III group. These fndings provide
essential insights into the molecular characteristics of ASFV variants in Serbia and contribute to the knowledge of circulating
strains of ASFV in Europe. However, further research is necessary to gain a better understanding of ASFV spread and evolution",
publisher = "Springer",
journal = "Veterinary Research Communications",
title = "Genetic analysis reveals multiple intergenic region and central variable region in the African swine fever virus variants circulating in Serbia",
volume = "47",
number = "4",
pages = "1925-1936",
doi = "10.1007/s11259-023-10145-7"
}

Glišić, D., Milićević, V., Krnjaić, D., Toplak, I., Prodanović, R., Gallardo, C.,& Radojičić, S.. (2023). Genetic analysis reveals multiple intergenic region and central variable region in the African swine fever virus variants circulating in Serbia. in Veterinary Research Communications
Springer., 47(4), 1925-1936.
https://doi.org/10.1007/s11259-023-10145-7

Glišić D, Milićević V, Krnjaić D, Toplak I, Prodanović R, Gallardo C, Radojičić S. Genetic analysis reveals multiple intergenic region and central variable region in the African swine fever virus variants circulating in Serbia. in Veterinary Research Communications. 2023;47(4):1925-1936.
doi:10.1007/s11259-023-10145-7 .

Glišić, Dimitrije, Milićević, Vesna, Krnjaić, Dejan, Toplak, Ivan, Prodanović, Radiša, Gallardo, Carmina, Radojičić, Sonja, "Genetic analysis reveals multiple intergenic region and central variable region in the African swine fever virus variants circulating in Serbia" in Veterinary Research Communications, 47, no. 4 (2023):1925-1936,
https://doi.org/10.1007/s11259-023-10145-7 . .

TY  - CONF
AU  - Glišić, Dimitrije
AU  - Milićević, Vesna
AU  - Krnjaić, Dejan
AU  - Prodanović, Radiša
AU  - Toplak, Ivan
AU  - Radojičić, Sonja
PY  - 2023
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/3208
AB  - Afrička kuga svinja (AKS) je virusno hemoragično oboljenje domaćih i divljih
svinja visokog stepena letaliteta, koje uzrokuje enormne ekonomske gubitke u
industriji svinja. Uzročnik afričke kuge je istoimeni virus, jedini pripadnik familije
Asfarviride i roda Asfivirus (Alonso i sar., 2018). Bolest je prvi put zabeležena u Srbiji
2019. godine u populaciji domaćih svinja, a od 2020. godine i u populaciji divljih svinja.
Od tada do danas broj svinja je smanjen za 7% što je više od prosečnog pada broja
svinja u Evropi od 4%. Genom virusa AKS je dvolančana linearna DNK dužine 170-190
kbp u zavisnosti od genotipa, podgenotipa i broja ponavljajućih segmenata i kodira
sintezu 170 virusnih proteina (Blome i sar., 2020). Održavanje virusa u prirodi zavisi
od faktora sredine, prisustva prijemčivih jedinki (divljih svinja) i otpornosti virusa.
Jedan od ključnih uslova za održavanje i cirkulaciju virusa je i visoka prevalencija
infekcije kod domaćih svinja (>5%) jer se na taj način omogućava prelivanje infekcije
na divlje svinje i zatvaranje kruga prenošenja (Aguilar-Vega i sar., 2023). Letalitet kod
divljih svinja inficiranih visoko virulentnim sojem iznosi 100%. Virus ostaje infektivan
3 meseca u leševima divljih svinja koje, ukoliko nisu uklonjene, dugotrajno
predstavljaju izvor infekcije. Brzina širenja infekcije u populaciji divljih svinja u Evropi
iznosi 4-17 km godišnje (Anette i sar., 2020). Širenje AKS na veće razdaljine uslovljeno
je antropogenim faktorom. Čovek kontaktom sa zaraženim ili uginulim divljim
svinjama, hranjenjem svinja kontaminiranim proizvodima animalnog porekla,
transportom zaraženih domaćih svinja iz jednog područija u drugo predstavlja
mehanički vektor za širenje virusa. Na afričkom kontinentu zabeležena su 24 genotipa
virusa koja cirkulišu između populacija bradavičastih svinja, mekih krpelja iz roda
Ornithodorus spp. i domaćih svinja. Van Afrike zabeleženi su samo genotip I i genotip
II virusa AKS. Za trenutnu epizootiju odgovoran je genotip II virusa. Autori Gallardo i
sar. (2023) su na osnovu analize genoma virusa AKS zabaležili 24 genogrupe u okviru genotipa II virusa na tlu Evrope. Na osnovu analize B646L i E183L gena opisan je jedan
genotip virusa (genotip II). Daljom analizom B602L gena definisana su dva
podgenotipa (CVR1 i 2) sa većim brojem varijacija koje zavise od broja tačkastih
mutacija. Na osnovu analize intergenskog segmenta (I73L - I329L), mogu se opisati
četiri podgenotipa (I-IV) (Gallardo i sar., 2023).
Laboratorijska dijagnostika afričke kuge se vrši primenom molekularnih metoda.
Cilj ovog rada je bila analiza cikulišućih sojeva virusa AKS u Srbiji. Trijažna testiranja
su vršena real-time PCR testom. Dok je dalja analiza vršena primenom klasičnog PCR
testa i Sanger sekvenciranja. Za detaljnu karakterizaciju lokalnih sojeva virusa AKS
odabrano je 95 uzoraka poreklom od domacih i divljih svinja obolelih od AKS u
periodu od 2019-2023 godine. Amplifikovana su i sekvencirana četiri segmenta
virusnog genoma (B646L, E183L, B602L i intergenski region između I73L - I329L). Na
osnovu analize ovih delova genoma utvrđeno je prisustvo više različitih sojeva virusa
u Srbiji. Istovremena cirkulacija nekoliko sojeva može biti posledica spontanih
mutacija ili reintrodukcije virusa iz drugih zaraženih područja. Utvrđivanje promena
u genskom materijalu smatraju se veoma značajnim informacijama jer mogu ukazivati
na adaptaciju virusa i modifikaciju virulentnosti. Praćenje promena u genomu virusa,
porsedno daje uvid u strukturu virusnih proteina. Dugotrajna cirkulacija virusa u
populaciji divljih svinja može dovesti do pojave srednje i niskovirulentnih sojeva što
predstavlja izazov za eradikaciju bolesti. Kod domaćih svinja, srednje i niskovirulentni
sojevi mogu izazvati atipične kliničke znakove i produženi tok bolesti što otežava
postavljanje sumnje, odlaže dijagnostiku i povećava rizik od širenja bolesti.
Potencijalne promene u konzerviranom delu genoma mogu otežati dijagnostiku
virusa. Stoga su izolacija i genska karakterizacija virusa afričke kuge svinja od
izuzetnog značaja za razumevanje epizootiologije ove bolesti. Poznavanje genskih
karakteristika lokalnih sojeva virusa omogućava praćenje njihovog evolutivnog
razvoja i identifikaciju novih sojeva. Na osnovu ovih podataka treba vršiti procenu
efikasnosti preduzetih mera za suzbijanje i kontrolu bolesti. Usled nedostatka
komercijalno dostupne vackcine, primena rigoroznih biosigurnostih mera je od
najvećeg značaja za sprečavanje unosa uzročnika u populaciju domaćih svinja. Stroge
kontrole na granicama su neophodne radi sprečavanja reintrodukcije virusa iz drugih
zaraženih područija, kao i brza reakcija u aktivnim žarištima radi sprečavanja daljeg
širenja bolesti i većih ekonomskih gubitaka.
AB  - African Swine Fever (ASF) is a highly lethal viral hemorrhagic disease affecting
domestic and wild pigs, causing significant economic losses in the swine industry. The
causative agent of ASF is a virus of the Asfarviridae family and Asfivirus genus (Alonso
et al., 2018). The disease was first recorded in Serbia in 2019 in domestic pig
populations, and since 2020, it has also been found in wild pig populations. Since then,
the number of pigs has decreased by 7%, which is higher than the average decline in
pig numbers in Europe (4%). The genome of the ASF virus is a double-stranded linear
DNA, ranging from 170-190 kbp in length, depending on the genotype, subgenotype,
and number of repetitive segments, encoding the synthesis of 170 viral proteins
(Blome et al., 2020). The maintenance of the virus in the environment depends on
environmental factors, the presence of susceptible individuals (wild pigs), and the
virus's ability to survive in that environment. A key condition for the maintenance and
circulation of the virus is a high prevalence of infection in domestic pigs (>5%), as it
enables the spill-over of infection to wild pigs, completing the transmission cycle
(Aguilar-Vega et al., 2023). The case fatality rate in wild pigs infected with highly
virulent strains is 100%. The virus remains infectious for 3 months in carcasses of wild
pigs, which, if not removed, serve as a long-term source of infection. The spread of
infection in the wild pig population in Europe is estimated at 4-17 km per year, with
anthropogenic factors playing a significant role in long-distance transmission (Anette
et al., 2020). Human contact with infected or dead wild pigs, feeding pigs with
contaminated animal-derived products, and the transport of infected domestic pigs
from one area to another act as mechanical vectors for virus spread. In Africa, 24
genotypes of the virus have been recorded, circulating among populations of bush
pigs, soft ticks of the Ornithodorus spp. genus, and domestic pigs. Outside of Africa,
only genotype I and genotype II of the ASF virus have been identified. The current epidemic is caused by the genotype II virus. Based on the genome analysis of the ASF
virus Gallardo et al. (2023), identified 24 genogroups within the genotype II virus in
Europe. From the analysis of the B646L and E183L genes, one virus strain (genotype
II) was described. Further analysis of the B602L gene defined two subgenotypes
(CVR1 and 2) with a higher number of variations depending on the number of point
mutations. Based on the analysis of the intergenic segment (I73L - I329L), four
subgenotypes (I-IV) can be described (Gallardo et al., 2023). Laboratory diagnostics of
African Swine Fever are conducted using molecular methods. The aim of this study
was to analyze circulating strains of ASF virus in Serbia. Screening tests were
performed using real-time PCR, while further analysis was conducted using
conventional PCR and Sanger sequencing. For a detailed characterization of local
strains of ASF virus, 95 samples from diseased domestic and wild pigs with ASF
between 2019 and 2023 were selected. Four segments of the viral genome (B646L,
E183L, B602L, and the intergenic region between I73L - I329L) were amplified and
sequenced. Based on the analysis of these genome segments, the presence of multiple
different strains of the virus was identified in Serbia. Simultaneous circulation of
several strains may result from spontaneous mutations or virus reintroduction from
other infected areas. Determining changes in the genetic material is considered highly
significant as they can indicate virus adaptation and modification of virulence.
Monitoring changes in the virus genome provides insight into the structure of viral
proteins. Prolonged circulation of the virus in the wild pig population can lead to the
emergence of moderately and low-virulent strains, posing challenges for disease
eradication. In domestic pigs, these strains can cause atypical clinical signs and
prolonged disease courses, complicating suspicion, delaying diagnosis, and increasing
the risk of disease spread. Potential changes in conserved regions of the genome can
hinder virus diagnostics. Therefore, the isolation and genetic characterization of ASF
virus strains are of utmost importance for understanding the epizootiology of this
disease. Knowledge of the genetic characteristics of local virus strains allows for
monitoring their evolutionary development and identification of new strains. Based
on these data, an assessment of the effectiveness of control measures should be
conducted. Due to the lack of commercially available vaccines, the implementation of
rigorous biosecurity measures is of paramount importance to prevent the
introduction of the pathogen into the domestic pig population. Strict controls at
borders are necessary to prevent the reintroduction of the virus from other infected
areas, along with swift responses in active outbreak areas to prevent further disease
spread and mitigate significant economic losses.
PB  - Beograd : Srpsko veterinarsko društvo
C3  - 34. Savetovanje veterinara Srbije, Zlatibor, 07 - 10. septembar 2023
T1  - Genska varijabilnost virusa afričke kuge svinja u Srbiji
T1  - Genetic variability of African Swine Fever virus in Serbia
SP  - 24
EP  - 28
UR  - https://hdl.handle.net/21.15107/rcub_veterinar_3208
ER  - 

@conference{
author = "Glišić, Dimitrije and Milićević, Vesna and Krnjaić, Dejan and Prodanović, Radiša and Toplak, Ivan and Radojičić, Sonja",
year = "2023",
abstract = "Afrička kuga svinja (AKS) je virusno hemoragično oboljenje domaćih i divljih
svinja visokog stepena letaliteta, koje uzrokuje enormne ekonomske gubitke u
industriji svinja. Uzročnik afričke kuge je istoimeni virus, jedini pripadnik familije
Asfarviride i roda Asfivirus (Alonso i sar., 2018). Bolest je prvi put zabeležena u Srbiji
2019. godine u populaciji domaćih svinja, a od 2020. godine i u populaciji divljih svinja.
Od tada do danas broj svinja je smanjen za 7% što je više od prosečnog pada broja
svinja u Evropi od 4%. Genom virusa AKS je dvolančana linearna DNK dužine 170-190
kbp u zavisnosti od genotipa, podgenotipa i broja ponavljajućih segmenata i kodira
sintezu 170 virusnih proteina (Blome i sar., 2020). Održavanje virusa u prirodi zavisi
od faktora sredine, prisustva prijemčivih jedinki (divljih svinja) i otpornosti virusa.
Jedan od ključnih uslova za održavanje i cirkulaciju virusa je i visoka prevalencija
infekcije kod domaćih svinja (>5%) jer se na taj način omogućava prelivanje infekcije
na divlje svinje i zatvaranje kruga prenošenja (Aguilar-Vega i sar., 2023). Letalitet kod
divljih svinja inficiranih visoko virulentnim sojem iznosi 100%. Virus ostaje infektivan
3 meseca u leševima divljih svinja koje, ukoliko nisu uklonjene, dugotrajno
predstavljaju izvor infekcije. Brzina širenja infekcije u populaciji divljih svinja u Evropi
iznosi 4-17 km godišnje (Anette i sar., 2020). Širenje AKS na veće razdaljine uslovljeno
je antropogenim faktorom. Čovek kontaktom sa zaraženim ili uginulim divljim
svinjama, hranjenjem svinja kontaminiranim proizvodima animalnog porekla,
transportom zaraženih domaćih svinja iz jednog područija u drugo predstavlja
mehanički vektor za širenje virusa. Na afričkom kontinentu zabeležena su 24 genotipa
virusa koja cirkulišu između populacija bradavičastih svinja, mekih krpelja iz roda
Ornithodorus spp. i domaćih svinja. Van Afrike zabeleženi su samo genotip I i genotip
II virusa AKS. Za trenutnu epizootiju odgovoran je genotip II virusa. Autori Gallardo i
sar. (2023) su na osnovu analize genoma virusa AKS zabaležili 24 genogrupe u okviru genotipa II virusa na tlu Evrope. Na osnovu analize B646L i E183L gena opisan je jedan
genotip virusa (genotip II). Daljom analizom B602L gena definisana su dva
podgenotipa (CVR1 i 2) sa većim brojem varijacija koje zavise od broja tačkastih
mutacija. Na osnovu analize intergenskog segmenta (I73L - I329L), mogu se opisati
četiri podgenotipa (I-IV) (Gallardo i sar., 2023).
Laboratorijska dijagnostika afričke kuge se vrši primenom molekularnih metoda.
Cilj ovog rada je bila analiza cikulišućih sojeva virusa AKS u Srbiji. Trijažna testiranja
su vršena real-time PCR testom. Dok je dalja analiza vršena primenom klasičnog PCR
testa i Sanger sekvenciranja. Za detaljnu karakterizaciju lokalnih sojeva virusa AKS
odabrano je 95 uzoraka poreklom od domacih i divljih svinja obolelih od AKS u
periodu od 2019-2023 godine. Amplifikovana su i sekvencirana četiri segmenta
virusnog genoma (B646L, E183L, B602L i intergenski region između I73L - I329L). Na
osnovu analize ovih delova genoma utvrđeno je prisustvo više različitih sojeva virusa
u Srbiji. Istovremena cirkulacija nekoliko sojeva može biti posledica spontanih
mutacija ili reintrodukcije virusa iz drugih zaraženih područja. Utvrđivanje promena
u genskom materijalu smatraju se veoma značajnim informacijama jer mogu ukazivati
na adaptaciju virusa i modifikaciju virulentnosti. Praćenje promena u genomu virusa,
porsedno daje uvid u strukturu virusnih proteina. Dugotrajna cirkulacija virusa u
populaciji divljih svinja može dovesti do pojave srednje i niskovirulentnih sojeva što
predstavlja izazov za eradikaciju bolesti. Kod domaćih svinja, srednje i niskovirulentni
sojevi mogu izazvati atipične kliničke znakove i produženi tok bolesti što otežava
postavljanje sumnje, odlaže dijagnostiku i povećava rizik od širenja bolesti.
Potencijalne promene u konzerviranom delu genoma mogu otežati dijagnostiku
virusa. Stoga su izolacija i genska karakterizacija virusa afričke kuge svinja od
izuzetnog značaja za razumevanje epizootiologije ove bolesti. Poznavanje genskih
karakteristika lokalnih sojeva virusa omogućava praćenje njihovog evolutivnog
razvoja i identifikaciju novih sojeva. Na osnovu ovih podataka treba vršiti procenu
efikasnosti preduzetih mera za suzbijanje i kontrolu bolesti. Usled nedostatka
komercijalno dostupne vackcine, primena rigoroznih biosigurnostih mera je od
najvećeg značaja za sprečavanje unosa uzročnika u populaciju domaćih svinja. Stroge
kontrole na granicama su neophodne radi sprečavanja reintrodukcije virusa iz drugih
zaraženih područija, kao i brza reakcija u aktivnim žarištima radi sprečavanja daljeg
širenja bolesti i većih ekonomskih gubitaka., African Swine Fever (ASF) is a highly lethal viral hemorrhagic disease affecting
domestic and wild pigs, causing significant economic losses in the swine industry. The
causative agent of ASF is a virus of the Asfarviridae family and Asfivirus genus (Alonso
et al., 2018). The disease was first recorded in Serbia in 2019 in domestic pig
populations, and since 2020, it has also been found in wild pig populations. Since then,
the number of pigs has decreased by 7%, which is higher than the average decline in
pig numbers in Europe (4%). The genome of the ASF virus is a double-stranded linear
DNA, ranging from 170-190 kbp in length, depending on the genotype, subgenotype,
and number of repetitive segments, encoding the synthesis of 170 viral proteins
(Blome et al., 2020). The maintenance of the virus in the environment depends on
environmental factors, the presence of susceptible individuals (wild pigs), and the
virus's ability to survive in that environment. A key condition for the maintenance and
circulation of the virus is a high prevalence of infection in domestic pigs (>5%), as it
enables the spill-over of infection to wild pigs, completing the transmission cycle
(Aguilar-Vega et al., 2023). The case fatality rate in wild pigs infected with highly
virulent strains is 100%. The virus remains infectious for 3 months in carcasses of wild
pigs, which, if not removed, serve as a long-term source of infection. The spread of
infection in the wild pig population in Europe is estimated at 4-17 km per year, with
anthropogenic factors playing a significant role in long-distance transmission (Anette
et al., 2020). Human contact with infected or dead wild pigs, feeding pigs with
contaminated animal-derived products, and the transport of infected domestic pigs
from one area to another act as mechanical vectors for virus spread. In Africa, 24
genotypes of the virus have been recorded, circulating among populations of bush
pigs, soft ticks of the Ornithodorus spp. genus, and domestic pigs. Outside of Africa,
only genotype I and genotype II of the ASF virus have been identified. The current epidemic is caused by the genotype II virus. Based on the genome analysis of the ASF
virus Gallardo et al. (2023), identified 24 genogroups within the genotype II virus in
Europe. From the analysis of the B646L and E183L genes, one virus strain (genotype
II) was described. Further analysis of the B602L gene defined two subgenotypes
(CVR1 and 2) with a higher number of variations depending on the number of point
mutations. Based on the analysis of the intergenic segment (I73L - I329L), four
subgenotypes (I-IV) can be described (Gallardo et al., 2023). Laboratory diagnostics of
African Swine Fever are conducted using molecular methods. The aim of this study
was to analyze circulating strains of ASF virus in Serbia. Screening tests were
performed using real-time PCR, while further analysis was conducted using
conventional PCR and Sanger sequencing. For a detailed characterization of local
strains of ASF virus, 95 samples from diseased domestic and wild pigs with ASF
between 2019 and 2023 were selected. Four segments of the viral genome (B646L,
E183L, B602L, and the intergenic region between I73L - I329L) were amplified and
sequenced. Based on the analysis of these genome segments, the presence of multiple
different strains of the virus was identified in Serbia. Simultaneous circulation of
several strains may result from spontaneous mutations or virus reintroduction from
other infected areas. Determining changes in the genetic material is considered highly
significant as they can indicate virus adaptation and modification of virulence.
Monitoring changes in the virus genome provides insight into the structure of viral
proteins. Prolonged circulation of the virus in the wild pig population can lead to the
emergence of moderately and low-virulent strains, posing challenges for disease
eradication. In domestic pigs, these strains can cause atypical clinical signs and
prolonged disease courses, complicating suspicion, delaying diagnosis, and increasing
the risk of disease spread. Potential changes in conserved regions of the genome can
hinder virus diagnostics. Therefore, the isolation and genetic characterization of ASF
virus strains are of utmost importance for understanding the epizootiology of this
disease. Knowledge of the genetic characteristics of local virus strains allows for
monitoring their evolutionary development and identification of new strains. Based
on these data, an assessment of the effectiveness of control measures should be
conducted. Due to the lack of commercially available vaccines, the implementation of
rigorous biosecurity measures is of paramount importance to prevent the
introduction of the pathogen into the domestic pig population. Strict controls at
borders are necessary to prevent the reintroduction of the virus from other infected
areas, along with swift responses in active outbreak areas to prevent further disease
spread and mitigate significant economic losses.",
publisher = "Beograd : Srpsko veterinarsko društvo",
journal = "34. Savetovanje veterinara Srbije, Zlatibor, 07 - 10. septembar 2023",
title = "Genska varijabilnost virusa afričke kuge svinja u Srbiji, Genetic variability of African Swine Fever virus in Serbia",
pages = "24-28",
url = "https://hdl.handle.net/21.15107/rcub_veterinar_3208"
}

Glišić, D., Milićević, V., Krnjaić, D., Prodanović, R., Toplak, I.,& Radojičić, S.. (2023). Genska varijabilnost virusa afričke kuge svinja u Srbiji. in 34. Savetovanje veterinara Srbije, Zlatibor, 07 - 10. septembar 2023
Beograd : Srpsko veterinarsko društvo., 24-28.
https://hdl.handle.net/21.15107/rcub_veterinar_3208

Glišić D, Milićević V, Krnjaić D, Prodanović R, Toplak I, Radojičić S. Genska varijabilnost virusa afričke kuge svinja u Srbiji. in 34. Savetovanje veterinara Srbije, Zlatibor, 07 - 10. septembar 2023. 2023;:24-28.
https://hdl.handle.net/21.15107/rcub_veterinar_3208 .

Glišić, Dimitrije, Milićević, Vesna, Krnjaić, Dejan, Prodanović, Radiša, Toplak, Ivan, Radojičić, Sonja, "Genska varijabilnost virusa afričke kuge svinja u Srbiji" in 34. Savetovanje veterinara Srbije, Zlatibor, 07 - 10. septembar 2023 (2023):24-28,
https://hdl.handle.net/21.15107/rcub_veterinar_3208 .

TY  - CONF
AU  - Kirovski, Danijela
AU  - Jovanović, Ljubomir
AU  - Bošnjaković, Dušan
AU  - Stojić, Milica
AU  - Prodanović, Radiša
AU  - Nedić, Sreten
AU  - Vujanac, Ivan
PY  - 2022
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/2415
AB  - Porast emisije gasova sa efektom staklene bašte dovodi do globalnog zagrevanja, izazivajući ireverzibilne promene u životnoj sredini. Glavni gasovi sa efektom staklene bašte su ugljen dioksid (CO2
),
metan (CH4
) i azot suboksid (N2
O), koji doprinose ukupnoj emisiji sa
55%, 15% i 6%, pojedinačno. Iako je procenat zastupljenosti CH4
 manji od CO2
, njegov ukupni globalni potencijal zagrevanja je 28 puta veći od CO2
. U ukupnoj antropogenoj emisiji gasova sa efektom staklene
bašte, stočarska proizvodnja učestvuje sa 14,5% sa najvećim doprinosom u emisiji CH4 (44%). U odnosu na ostale sektore stočarske proizvodnje, uzgoj goveda najviše doprinosi efektu staklene bašte pri čemu visoko mlečne krave imaju vodeću ulogu, pošto je produkcija ovih
gasova uključujući i CH4
, vezana za aktivnost buraga. Visoko mlečne
krave proizvode CH4
 pretežno (90%) enteričnom fermentacijom. Naime, metanogene bakterije buraga konvertuju stvoreni CO2
 i H2
 u CH4
,
koji zatim eliminišu pretežno podrigivanjem. Preostali deo CH4
 sa farmi krava potiče iz fecesa. Umanjenje emisije CH4
 iz fecesa se postiže primenom odgovarajućeg sistema upravljanja stajnjakom, dok je
umanjenje emisije putem enterične fermentacije značajno veći izazov
za naučnu zajednicu i moguće ga je ostvariti korišćenjem različitih nutritivnih strategija koje preusmeravaju metaboličke puteve koji vode
ka proizvodnji CH4 ka onima koji vode ka porastu proizvodnje mleka.
AB  - versible environmental changes. The major greenhouse gases are carbon dioxide (CO2
),
methane (CH4
) and nitrous oxide (N2
O), contributing to overall emission with 55%, 15% and
6%, respectively. Although CH4 percentage content is lower than CO2
, its global warming
potential is 28 times greater than CO2
. In global anthropogenic emissions of greenhouse
gases, the livestock sector contributes 14.5% with CH4
 emission contributing most
(44%). Compared to other livestock subsectors, cattle production has major contribution to greenhouse effect, with dairy cows having leading position, since production of these
gases, including CH4
, is associated with rumen activity. Dairy cows produce CH4
 mainly by
enteric fermentation (90%). Namely, within rumen methanogenic microorganisms convert
produced CO2 and H2 to CH4
, which is eliminated mainly by burping. The rest of CH4 from
dairy farms originates from manure. Mitigation of methane from manure is achieved by
applying adequate manure management system, but mitigation of methane from enteric
fermentation is more challenging for scientific community and is possible to obtain by using
different nutritional strategies which may redirect metabolic pathways that lead to CH4
production in those which leads to increased milk production.
PB  - Fakultet veterinarske medicine, Centar za izdavačku delatnost i promet učila
C3  - Zbornik radova - XLIII seminar inovacija znanja veterinara
T1  - Emisija metana sa farmi visokomlečnih krava – potencijalni rizik za životnu sredinu
T1  - Methane emission from dairy farms – potential environmental risk
SP  - 35
EP  - 48
UR  - https://hdl.handle.net/21.15107/rcub_veterinar_2415
ER  - 

@conference{
author = "Kirovski, Danijela and Jovanović, Ljubomir and Bošnjaković, Dušan and Stojić, Milica and Prodanović, Radiša and Nedić, Sreten and Vujanac, Ivan",
year = "2022",
abstract = "Porast emisije gasova sa efektom staklene bašte dovodi do globalnog zagrevanja, izazivajući ireverzibilne promene u životnoj sredini. Glavni gasovi sa efektom staklene bašte su ugljen dioksid (CO2
),
metan (CH4
) i azot suboksid (N2
O), koji doprinose ukupnoj emisiji sa
55%, 15% i 6%, pojedinačno. Iako je procenat zastupljenosti CH4
 manji od CO2
, njegov ukupni globalni potencijal zagrevanja je 28 puta veći od CO2
. U ukupnoj antropogenoj emisiji gasova sa efektom staklene
bašte, stočarska proizvodnja učestvuje sa 14,5% sa najvećim doprinosom u emisiji CH4 (44%). U odnosu na ostale sektore stočarske proizvodnje, uzgoj goveda najviše doprinosi efektu staklene bašte pri čemu visoko mlečne krave imaju vodeću ulogu, pošto je produkcija ovih
gasova uključujući i CH4
, vezana za aktivnost buraga. Visoko mlečne
krave proizvode CH4
 pretežno (90%) enteričnom fermentacijom. Naime, metanogene bakterije buraga konvertuju stvoreni CO2
 i H2
 u CH4
,
koji zatim eliminišu pretežno podrigivanjem. Preostali deo CH4
 sa farmi krava potiče iz fecesa. Umanjenje emisije CH4
 iz fecesa se postiže primenom odgovarajućeg sistema upravljanja stajnjakom, dok je
umanjenje emisije putem enterične fermentacije značajno veći izazov
za naučnu zajednicu i moguće ga je ostvariti korišćenjem različitih nutritivnih strategija koje preusmeravaju metaboličke puteve koji vode
ka proizvodnji CH4 ka onima koji vode ka porastu proizvodnje mleka., versible environmental changes. The major greenhouse gases are carbon dioxide (CO2
),
methane (CH4
) and nitrous oxide (N2
O), contributing to overall emission with 55%, 15% and
6%, respectively. Although CH4 percentage content is lower than CO2
, its global warming
potential is 28 times greater than CO2
. In global anthropogenic emissions of greenhouse
gases, the livestock sector contributes 14.5% with CH4
 emission contributing most
(44%). Compared to other livestock subsectors, cattle production has major contribution to greenhouse effect, with dairy cows having leading position, since production of these
gases, including CH4
, is associated with rumen activity. Dairy cows produce CH4
 mainly by
enteric fermentation (90%). Namely, within rumen methanogenic microorganisms convert
produced CO2 and H2 to CH4
, which is eliminated mainly by burping. The rest of CH4 from
dairy farms originates from manure. Mitigation of methane from manure is achieved by
applying adequate manure management system, but mitigation of methane from enteric
fermentation is more challenging for scientific community and is possible to obtain by using
different nutritional strategies which may redirect metabolic pathways that lead to CH4
production in those which leads to increased milk production.",
publisher = "Fakultet veterinarske medicine, Centar za izdavačku delatnost i promet učila",
journal = "Zbornik radova - XLIII seminar inovacija znanja veterinara",
title = "Emisija metana sa farmi visokomlečnih krava – potencijalni rizik za životnu sredinu, Methane emission from dairy farms – potential environmental risk",
pages = "35-48",
url = "https://hdl.handle.net/21.15107/rcub_veterinar_2415"
}

Kirovski, D., Jovanović, L., Bošnjaković, D., Stojić, M., Prodanović, R., Nedić, S.,& Vujanac, I.. (2022). Emisija metana sa farmi visokomlečnih krava – potencijalni rizik za životnu sredinu. in Zbornik radova - XLIII seminar inovacija znanja veterinara
Fakultet veterinarske medicine, Centar za izdavačku delatnost i promet učila., 35-48.
https://hdl.handle.net/21.15107/rcub_veterinar_2415

Kirovski D, Jovanović L, Bošnjaković D, Stojić M, Prodanović R, Nedić S, Vujanac I. Emisija metana sa farmi visokomlečnih krava – potencijalni rizik za životnu sredinu. in Zbornik radova - XLIII seminar inovacija znanja veterinara. 2022;:35-48.
https://hdl.handle.net/21.15107/rcub_veterinar_2415 .

Kirovski, Danijela, Jovanović, Ljubomir, Bošnjaković, Dušan, Stojić, Milica, Prodanović, Radiša, Nedić, Sreten, Vujanac, Ivan, "Emisija metana sa farmi visokomlečnih krava – potencijalni rizik za životnu sredinu" in Zbornik radova - XLIII seminar inovacija znanja veterinara (2022):35-48,
https://hdl.handle.net/21.15107/rcub_veterinar_2415 .

TY  - CONF
AU  - Vujanac, Ivan
AU  - Prodanović, Radiša
AU  - Nedić, Sreten
AU  - Arsić, Sveta
AU  - Bojkovski, Jovan
AU  - Jovanović, Ljubomir
AU  - Kirovski, Danijela
PY  - 2022
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/2423
AB  - Neonatalne dijareje kod domaćih preživara predstavljaju jedan
od najznačajnijih zdravstvenih problema u stočarskoj proizvodnji širom sveta. One predstavljaju jedan od najčešćih uzroka smrti kod teladi mlečnih rasa goveda u prvih 30 dana života, ali su takođe i značajan
zdravstveni problem kod jagnjadi i jaradi. Osim direktnih ekonomskih
šteta izazvanih visokim troškovima lečenja i mortalitetom novorođenčadi, neonatalne dijareje mogu da imaju i ozbiljne dugoročne posledice po rast i razvoj podmlatka namenjenog za priplod. Prema uzrocima
koji dovode do nastanka neonatalnih dijareja one mogu biti neinfektivne i infektivne etiologije. Najčešći neinfektivni uzroci nastanka neonatalnih dijareja su greške u tehnologiji ishrane, loš kvalitet kolostruma,
mleka ili zamena za mleko kao i greške prilikom zalučenja podmlatka.
Od infektivnih uzročnika neonatalnih dijareja najučestalije su infekcije
sa enterotoksičnim E. coli, Clostridium spp., Rotavirusi, Koronavirusi i
kriptosporidije. Imajući u vidu različitu etiologiju nastanka neonatalnih
dijareja, kao i značajne ekonomske gubitke koje nanose, upotreba savremenih pristupa u prevenciji i terapiji predstavlja imperativ u intenzivnoj farmskoj proizvodnji. To se ogleda u aktivnoj i pasivnoj imunizaciji novorođenčadi, eliminisanju grešaka u tehnologiji odgoja kao i u
primeni savremenih dijagnostičkih i terapijskih protokola. Značaj tačne
dijagnostike uzročnika neonatalnih dijareja bitan je faktor za uspešnu
terapiju. Primena svih ovih mera može značajno da smanji nastanak
neonatalnih dijareja kod domaćih preživara.
AB  - blems in livestock production worldwide. They are one of the most common causes of
death in dairy calves in the first 30 days of life, but they are also a significant health problem
in lambs and kids. In addition to the direct economic damage caused by high treatment
costs and infant mortality, neonatal diarrhea can have serious long-term consequences for
the growth and development of offspring intended for breeding. According to the causes
that lead to neonatal diarrhea, they can be of non-infectious and infectious etiology. The
most common non-infectious causes of neonatal diarrhea are errors in dietary technology,
poor quality of colostrum, milk or milk replacements, as well as errors in weaning offspring.
Of the infectious causes of neonatal diarrhea, the most common are infections with
enterotoxigenic E. coli, Clostridium spp., Rotaviruses, Coronaviruses and Cryptosporidia.
Given the different etiology of neonatal diarrhea, as well as the significant economic losses
they cause, the use of modern approaches in prevention and therapy is an imperative
in intensive farm production. This is reflected in the active and passive immunization of
newborns, the elimination of errors in nourishments technology as well as the application of
modern diagnostic and therapeutic protocols. The importance of accurate diagnosis of the  cause of neonatal diarrhea is an important factor for successful therapy. The application of
all these measures can significantly reduce the occurrence of neonatal diarrhea in domestic
ruminants.
PB  - Fakultet veterinarske medicine, Centar za izdavačku delatnost i promet učila
C3  - Zbornik radova - XLIII seminar inovacija znanja veterinara
T1  - Profilaksa i terapija neonatalnih dijareja kod domaćih preživara
T1  - Prevention and therapy of neonatal diarrhea in domestic ruminants
SP  - 125
EP  - 137
UR  - https://hdl.handle.net/21.15107/rcub_veterinar_2423
ER  - 

@conference{
author = "Vujanac, Ivan and Prodanović, Radiša and Nedić, Sreten and Arsić, Sveta and Bojkovski, Jovan and Jovanović, Ljubomir and Kirovski, Danijela",
year = "2022",
abstract = "Neonatalne dijareje kod domaćih preživara predstavljaju jedan
od najznačajnijih zdravstvenih problema u stočarskoj proizvodnji širom sveta. One predstavljaju jedan od najčešćih uzroka smrti kod teladi mlečnih rasa goveda u prvih 30 dana života, ali su takođe i značajan
zdravstveni problem kod jagnjadi i jaradi. Osim direktnih ekonomskih
šteta izazvanih visokim troškovima lečenja i mortalitetom novorođenčadi, neonatalne dijareje mogu da imaju i ozbiljne dugoročne posledice po rast i razvoj podmlatka namenjenog za priplod. Prema uzrocima
koji dovode do nastanka neonatalnih dijareja one mogu biti neinfektivne i infektivne etiologije. Najčešći neinfektivni uzroci nastanka neonatalnih dijareja su greške u tehnologiji ishrane, loš kvalitet kolostruma,
mleka ili zamena za mleko kao i greške prilikom zalučenja podmlatka.
Od infektivnih uzročnika neonatalnih dijareja najučestalije su infekcije
sa enterotoksičnim E. coli, Clostridium spp., Rotavirusi, Koronavirusi i
kriptosporidije. Imajući u vidu različitu etiologiju nastanka neonatalnih
dijareja, kao i značajne ekonomske gubitke koje nanose, upotreba savremenih pristupa u prevenciji i terapiji predstavlja imperativ u intenzivnoj farmskoj proizvodnji. To se ogleda u aktivnoj i pasivnoj imunizaciji novorođenčadi, eliminisanju grešaka u tehnologiji odgoja kao i u
primeni savremenih dijagnostičkih i terapijskih protokola. Značaj tačne
dijagnostike uzročnika neonatalnih dijareja bitan je faktor za uspešnu
terapiju. Primena svih ovih mera može značajno da smanji nastanak
neonatalnih dijareja kod domaćih preživara., blems in livestock production worldwide. They are one of the most common causes of
death in dairy calves in the first 30 days of life, but they are also a significant health problem
in lambs and kids. In addition to the direct economic damage caused by high treatment
costs and infant mortality, neonatal diarrhea can have serious long-term consequences for
the growth and development of offspring intended for breeding. According to the causes
that lead to neonatal diarrhea, they can be of non-infectious and infectious etiology. The
most common non-infectious causes of neonatal diarrhea are errors in dietary technology,
poor quality of colostrum, milk or milk replacements, as well as errors in weaning offspring.
Of the infectious causes of neonatal diarrhea, the most common are infections with
enterotoxigenic E. coli, Clostridium spp., Rotaviruses, Coronaviruses and Cryptosporidia.
Given the different etiology of neonatal diarrhea, as well as the significant economic losses
they cause, the use of modern approaches in prevention and therapy is an imperative
in intensive farm production. This is reflected in the active and passive immunization of
newborns, the elimination of errors in nourishments technology as well as the application of
modern diagnostic and therapeutic protocols. The importance of accurate diagnosis of the  cause of neonatal diarrhea is an important factor for successful therapy. The application of
all these measures can significantly reduce the occurrence of neonatal diarrhea in domestic
ruminants.",
publisher = "Fakultet veterinarske medicine, Centar za izdavačku delatnost i promet učila",
journal = "Zbornik radova - XLIII seminar inovacija znanja veterinara",
title = "Profilaksa i terapija neonatalnih dijareja kod domaćih preživara, Prevention and therapy of neonatal diarrhea in domestic ruminants",
pages = "125-137",
url = "https://hdl.handle.net/21.15107/rcub_veterinar_2423"
}

Vujanac, I., Prodanović, R., Nedić, S., Arsić, S., Bojkovski, J., Jovanović, L.,& Kirovski, D.. (2022). Profilaksa i terapija neonatalnih dijareja kod domaćih preživara. in Zbornik radova - XLIII seminar inovacija znanja veterinara
Fakultet veterinarske medicine, Centar za izdavačku delatnost i promet učila., 125-137.
https://hdl.handle.net/21.15107/rcub_veterinar_2423

Vujanac I, Prodanović R, Nedić S, Arsić S, Bojkovski J, Jovanović L, Kirovski D. Profilaksa i terapija neonatalnih dijareja kod domaćih preživara. in Zbornik radova - XLIII seminar inovacija znanja veterinara. 2022;:125-137.
https://hdl.handle.net/21.15107/rcub_veterinar_2423 .

Vujanac, Ivan, Prodanović, Radiša, Nedić, Sreten, Arsić, Sveta, Bojkovski, Jovan, Jovanović, Ljubomir, Kirovski, Danijela, "Profilaksa i terapija neonatalnih dijareja kod domaćih preživara" in Zbornik radova - XLIII seminar inovacija znanja veterinara (2022):125-137,
https://hdl.handle.net/21.15107/rcub_veterinar_2423 .

TY  - CONF
AU  - Bojkovski, Jovan
AU  - Zdravković, Nemanja
AU  - Vakanjac, Slobodanka
AU  - Prodanović, Radiša
AU  - Arsić, Sveta
AU  - Nedić, Sreten
AU  - Vujanac, Ivan
AU  - Angjelovski, Branko
AU  - Dobrosavljević, Ivan
AU  - Pavlović, Ivan
AU  - Obrenović, Sonja
PY  - 2022
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/2891
AB  - Intenzivna proizvodnja svinja na komercijalnim farmama nastoji da proizvede što veći broj odbijene prasadi odnosno tovljenika po krmači godišnje. Za postizanje ovakvih proizvodnih rezultata neophodno je uspostaviti visoku reproduktivnu efikasnost priplodnih životinja. Potrebna je adekvatna zdravstvena zaštita sa
dobrom organizacijom proizvodnje. Cilj rada je utvrđivanje reperoduktivne efikasnosti nerastova. Na jednoj komercijalnoj farmi smo pratili proizvodne rezultate
nerastova rase jorkšir, durok i holandski landras. U intenzivnom uzgoju svinja, više je validnih parametara kojima se može iskazati uspešnost odnosno profitabilnost proizvodnje, kao što su: broj živorođene ili odlučene prasadi, dnevni prirast,
dužina trajanja tova, broj neproduktivnih dana plotkinja i sl. Danas je uobičajeno
da se proizvodnja svinja na komercijalnim farmama prezentuje brojem odgajene prasadi odnosno isporučenih tovljenika po krmači u toku kalendarske godine.
AB  - Intensive production of pigs on commercial farms strives to produce the largest possible number of weaned piglets or fattening pigs per sow per year. To achieve such production results, it is necessary to establish a high reproductive efficiency of breeding animals. We need adequate health care with good organization of production. The aim of the article is to determine the reproductive efficiency
of boars. On a commercial farm, we monitored the production results of boars of the Yorkshire, Duroc and Dutch Landrace breed. In intensive pig breeding, there
are several valid parameters that can be used to show the success or profitability of production, such as: the number of live births or weaned piglets, daily gain,
duration of fattening, number of non-productive days of sows, etc. Today, it is customary to present pig production on commercial farms by the number of piglets
raised, i.e. delivered fatteners per sow during the calendar year.
PB  - Beograd : Fakultet veterinarske medicine, Centar za izdavačku delatnost i promet učila
C3  - 13. Naučni simpozijum Reprodukcija domaćih životinja, Divčibare, 6 - 9. oktobar 2022
T1  - Menadžment nerasta
SP  - 165
EP  - 169
UR  - https://hdl.handle.net/21.15107/rcub_veterinar_2891
ER  - 

@conference{
author = "Bojkovski, Jovan and Zdravković, Nemanja and Vakanjac, Slobodanka and Prodanović, Radiša and Arsić, Sveta and Nedić, Sreten and Vujanac, Ivan and Angjelovski, Branko and Dobrosavljević, Ivan and Pavlović, Ivan and Obrenović, Sonja",
year = "2022",
abstract = "Intenzivna proizvodnja svinja na komercijalnim farmama nastoji da proizvede što veći broj odbijene prasadi odnosno tovljenika po krmači godišnje. Za postizanje ovakvih proizvodnih rezultata neophodno je uspostaviti visoku reproduktivnu efikasnost priplodnih životinja. Potrebna je adekvatna zdravstvena zaštita sa
dobrom organizacijom proizvodnje. Cilj rada je utvrđivanje reperoduktivne efikasnosti nerastova. Na jednoj komercijalnoj farmi smo pratili proizvodne rezultate
nerastova rase jorkšir, durok i holandski landras. U intenzivnom uzgoju svinja, više je validnih parametara kojima se može iskazati uspešnost odnosno profitabilnost proizvodnje, kao što su: broj živorođene ili odlučene prasadi, dnevni prirast,
dužina trajanja tova, broj neproduktivnih dana plotkinja i sl. Danas je uobičajeno
da se proizvodnja svinja na komercijalnim farmama prezentuje brojem odgajene prasadi odnosno isporučenih tovljenika po krmači u toku kalendarske godine., Intensive production of pigs on commercial farms strives to produce the largest possible number of weaned piglets or fattening pigs per sow per year. To achieve such production results, it is necessary to establish a high reproductive efficiency of breeding animals. We need adequate health care with good organization of production. The aim of the article is to determine the reproductive efficiency
of boars. On a commercial farm, we monitored the production results of boars of the Yorkshire, Duroc and Dutch Landrace breed. In intensive pig breeding, there
are several valid parameters that can be used to show the success or profitability of production, such as: the number of live births or weaned piglets, daily gain,
duration of fattening, number of non-productive days of sows, etc. Today, it is customary to present pig production on commercial farms by the number of piglets
raised, i.e. delivered fatteners per sow during the calendar year.",
publisher = "Beograd : Fakultet veterinarske medicine, Centar za izdavačku delatnost i promet učila",
journal = "13. Naučni simpozijum Reprodukcija domaćih životinja, Divčibare, 6 - 9. oktobar 2022",
title = "Menadžment nerasta",
pages = "165-169",
url = "https://hdl.handle.net/21.15107/rcub_veterinar_2891"
}

Bojkovski, J., Zdravković, N., Vakanjac, S., Prodanović, R., Arsić, S., Nedić, S., Vujanac, I., Angjelovski, B., Dobrosavljević, I., Pavlović, I.,& Obrenović, S.. (2022). Menadžment nerasta. in 13. Naučni simpozijum Reprodukcija domaćih životinja, Divčibare, 6 - 9. oktobar 2022
Beograd : Fakultet veterinarske medicine, Centar za izdavačku delatnost i promet učila., 165-169.
https://hdl.handle.net/21.15107/rcub_veterinar_2891

Bojkovski J, Zdravković N, Vakanjac S, Prodanović R, Arsić S, Nedić S, Vujanac I, Angjelovski B, Dobrosavljević I, Pavlović I, Obrenović S. Menadžment nerasta. in 13. Naučni simpozijum Reprodukcija domaćih životinja, Divčibare, 6 - 9. oktobar 2022. 2022;:165-169.
https://hdl.handle.net/21.15107/rcub_veterinar_2891 .

Bojkovski, Jovan, Zdravković, Nemanja, Vakanjac, Slobodanka, Prodanović, Radiša, Arsić, Sveta, Nedić, Sreten, Vujanac, Ivan, Angjelovski, Branko, Dobrosavljević, Ivan, Pavlović, Ivan, Obrenović, Sonja, "Menadžment nerasta" in 13. Naučni simpozijum Reprodukcija domaćih životinja, Divčibare, 6 - 9. oktobar 2022 (2022):165-169,
https://hdl.handle.net/21.15107/rcub_veterinar_2891 .

TY  - JOUR
AU  - Prodanović, Radiša
AU  - Kirovski, Danijela
AU  - Vujanac, Ivan
AU  - Djordjevic, Ana
AU  - Romić, Snježana
AU  - Pantelić, Marija
AU  - Korićanac, Goran
PY  - 2022
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/2482
AB  - A number of alterations have been identified in lipid metabolism within adipose tissue and liver in obesity. Less is known about the capacity of skeletal muscle for the metabolism of fatty acids in obesity-related insulin resistance, though it is evident that dry cow muscles may contain increased triglyceride content. The current study was therefore undertaken to evaluate the skeletal muscle expression of proteins of the fatty acid metabolism in dry cows with different body condition scores (BCS). Sixteen Holstein-Friesian close-up cows were divided into 2 equal groups based on their BCS as optimal (3.25 ≤ BCS ≤ 3.5) and high (4.0 ≤ BCS ≤ 4.25). Blood samples collection and skeletal muscle biopsies were carried out at day 10 before calving. Blood serum was assayed for concentration of resistin using a bovine specific ELISA. Protein expression of insulin receptor beta subunit (IRβ), glucose transporter 4 (GLUT4), fatty acid translocase (FAT/CD36), fatty acid transporter 1 (FATP1), carnitine palmitoyltransferase 1 (CPT1), AMP-acitvated protein kinase (AMPK) and lipin 1 were analyzed in semitendinosus muscle by immunoblot. Resistin differed non-significantly between high-BCS and optimal-BCS cows. Insulin-resistant lipid metabolism in obese cows was paralleled with increased skeletal muscle expression of lipin 1 and GLUT4, and decreased expression of IRβ and FATP1. These data suggest that in obesity-related insulin resistance, metabolic capacity in dry cow skeletal muscles appears to be organized towards the synthesis of signaling intermediates rather than fatty acids oxidation and that altered fatty acid uptake does not contribute to this disposition.
PB  - Elsevier
T2  - Research in Veterinary Science
T1  - Obesity-related prepartal insulin resistance in dairy cows is associated with increased lipin 1 and decreased FATP 1 expression in skeletal muscle
VL  - 150
SP  - 189
EP  - 194
DO  - 10.1016/j.rvsc.2022.04.012
ER  - 

@article{
author = "Prodanović, Radiša and Kirovski, Danijela and Vujanac, Ivan and Djordjevic, Ana and Romić, Snježana and Pantelić, Marija and Korićanac, Goran",
year = "2022",
abstract = "A number of alterations have been identified in lipid metabolism within adipose tissue and liver in obesity. Less is known about the capacity of skeletal muscle for the metabolism of fatty acids in obesity-related insulin resistance, though it is evident that dry cow muscles may contain increased triglyceride content. The current study was therefore undertaken to evaluate the skeletal muscle expression of proteins of the fatty acid metabolism in dry cows with different body condition scores (BCS). Sixteen Holstein-Friesian close-up cows were divided into 2 equal groups based on their BCS as optimal (3.25 ≤ BCS ≤ 3.5) and high (4.0 ≤ BCS ≤ 4.25). Blood samples collection and skeletal muscle biopsies were carried out at day 10 before calving. Blood serum was assayed for concentration of resistin using a bovine specific ELISA. Protein expression of insulin receptor beta subunit (IRβ), glucose transporter 4 (GLUT4), fatty acid translocase (FAT/CD36), fatty acid transporter 1 (FATP1), carnitine palmitoyltransferase 1 (CPT1), AMP-acitvated protein kinase (AMPK) and lipin 1 were analyzed in semitendinosus muscle by immunoblot. Resistin differed non-significantly between high-BCS and optimal-BCS cows. Insulin-resistant lipid metabolism in obese cows was paralleled with increased skeletal muscle expression of lipin 1 and GLUT4, and decreased expression of IRβ and FATP1. These data suggest that in obesity-related insulin resistance, metabolic capacity in dry cow skeletal muscles appears to be organized towards the synthesis of signaling intermediates rather than fatty acids oxidation and that altered fatty acid uptake does not contribute to this disposition.",
publisher = "Elsevier",
journal = "Research in Veterinary Science",
title = "Obesity-related prepartal insulin resistance in dairy cows is associated with increased lipin 1 and decreased FATP 1 expression in skeletal muscle",
volume = "150",
pages = "189-194",
doi = "10.1016/j.rvsc.2022.04.012"
}

Prodanović, R., Kirovski, D., Vujanac, I., Djordjevic, A., Romić, S., Pantelić, M.,& Korićanac, G.. (2022). Obesity-related prepartal insulin resistance in dairy cows is associated with increased lipin 1 and decreased FATP 1 expression in skeletal muscle. in Research in Veterinary Science
Elsevier., 150, 189-194.
https://doi.org/10.1016/j.rvsc.2022.04.012

Prodanović R, Kirovski D, Vujanac I, Djordjevic A, Romić S, Pantelić M, Korićanac G. Obesity-related prepartal insulin resistance in dairy cows is associated with increased lipin 1 and decreased FATP 1 expression in skeletal muscle. in Research in Veterinary Science. 2022;150:189-194.
doi:10.1016/j.rvsc.2022.04.012 .

Prodanović, Radiša, Kirovski, Danijela, Vujanac, Ivan, Djordjevic, Ana, Romić, Snježana, Pantelić, Marija, Korićanac, Goran, "Obesity-related prepartal insulin resistance in dairy cows is associated with increased lipin 1 and decreased FATP 1 expression in skeletal muscle" in Research in Veterinary Science, 150 (2022):189-194,
https://doi.org/10.1016/j.rvsc.2022.04.012 . .

TY  - JOUR
AU  - Arsić, Sveta
AU  - Vujanac, Ivan
AU  - Bojkovski, Jovan
AU  - Kirovski, Danijela
AU  - Nedić, Sreten
AU  - Prodanović, Radiša
PY  - 2022
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/2526
AB  - This study aimed to evaluate the effects of two different treatment options for the
correction of left displaced abomasum (LDA) on milk yield, hematological, electrolyte
parameters, lactate and cortisol concentrations in primiparous cows. Twenty four
Holstein cows were randomly assigned into three groups: cows treated with one-step
laparoscopic abomasopexy (LPS, n=8), cows treated by left paralumbar omentopexy
(LPT, n=8) and healthy cows (CON, n=8), matched by parity and days in milk. Blood
samples were collected before (D0) and after (D0’) surgery, and 1 (D1), 3 (D3), 10
(D3) and 30 (D30) days following surgery. LPS and LPT cows at D0 as well as LPT
cows at 30 d following surgery had lower milk yield than CON cows (P<0.05), while
the service period was higher in LPT than in CON (P<0.05). WBC was lower at D0 as
well as Hb and Ht at D0 and D0’ in CON group than those of LPS and LPT (P<0.05).
Hyponatremia, hypochloremia and hypokalemia at D0 and D0’ were observed in LPS
and LPT. In addition, LPT cows had lower Na and Cl at D1 and D3 and lower K at
D1 than CON (P<0.05). Impaired hydration in LPS and LPT cows was accompanied
by higher concentrations of lactate at D0, D0’, D1 and D3 (P<0.01) and cortisol at D0
and D0’ (P<0.01) compared with CON group, while LPT had higher cortisol at D0’
than LPS (P<0.05). These results indicated that LPS has the potential to improve the
convalescence period of LDA in primiparous cows.
PB  - Sciendo
T2  - Beograd : Acta Veterinaria
T1  - Milk yield, hematological and electrolyte parameters in primiparous dairy cows after laparotomic omentopexy and one-step laparoscopic abomasopexy treatments of left displaced abomasum
VL  - 22
IS  - 4
SP  - 468
EP  - 484
DO  - 10.2478/acve-2022-0038
ER  - 

@article{
author = "Arsić, Sveta and Vujanac, Ivan and Bojkovski, Jovan and Kirovski, Danijela and Nedić, Sreten and Prodanović, Radiša",
year = "2022",
abstract = "This study aimed to evaluate the effects of two different treatment options for the
correction of left displaced abomasum (LDA) on milk yield, hematological, electrolyte
parameters, lactate and cortisol concentrations in primiparous cows. Twenty four
Holstein cows were randomly assigned into three groups: cows treated with one-step
laparoscopic abomasopexy (LPS, n=8), cows treated by left paralumbar omentopexy
(LPT, n=8) and healthy cows (CON, n=8), matched by parity and days in milk. Blood
samples were collected before (D0) and after (D0’) surgery, and 1 (D1), 3 (D3), 10
(D3) and 30 (D30) days following surgery. LPS and LPT cows at D0 as well as LPT
cows at 30 d following surgery had lower milk yield than CON cows (P<0.05), while
the service period was higher in LPT than in CON (P<0.05). WBC was lower at D0 as
well as Hb and Ht at D0 and D0’ in CON group than those of LPS and LPT (P<0.05).
Hyponatremia, hypochloremia and hypokalemia at D0 and D0’ were observed in LPS
and LPT. In addition, LPT cows had lower Na and Cl at D1 and D3 and lower K at
D1 than CON (P<0.05). Impaired hydration in LPS and LPT cows was accompanied
by higher concentrations of lactate at D0, D0’, D1 and D3 (P<0.01) and cortisol at D0
and D0’ (P<0.01) compared with CON group, while LPT had higher cortisol at D0’
than LPS (P<0.05). These results indicated that LPS has the potential to improve the
convalescence period of LDA in primiparous cows.",
publisher = "Sciendo",
journal = "Beograd : Acta Veterinaria",
title = "Milk yield, hematological and electrolyte parameters in primiparous dairy cows after laparotomic omentopexy and one-step laparoscopic abomasopexy treatments of left displaced abomasum",
volume = "22",
number = "4",
pages = "468-484",
doi = "10.2478/acve-2022-0038"
}

Arsić, S., Vujanac, I., Bojkovski, J., Kirovski, D., Nedić, S.,& Prodanović, R.. (2022). Milk yield, hematological and electrolyte parameters in primiparous dairy cows after laparotomic omentopexy and one-step laparoscopic abomasopexy treatments of left displaced abomasum. in Beograd : Acta Veterinaria
Sciendo., 22(4), 468-484.
https://doi.org/10.2478/acve-2022-0038

Arsić S, Vujanac I, Bojkovski J, Kirovski D, Nedić S, Prodanović R. Milk yield, hematological and electrolyte parameters in primiparous dairy cows after laparotomic omentopexy and one-step laparoscopic abomasopexy treatments of left displaced abomasum. in Beograd : Acta Veterinaria. 2022;22(4):468-484.
doi:10.2478/acve-2022-0038 .

Arsić, Sveta, Vujanac, Ivan, Bojkovski, Jovan, Kirovski, Danijela, Nedić, Sreten, Prodanović, Radiša, "Milk yield, hematological and electrolyte parameters in primiparous dairy cows after laparotomic omentopexy and one-step laparoscopic abomasopexy treatments of left displaced abomasum" in Beograd : Acta Veterinaria, 22, no. 4 (2022):468-484,
https://doi.org/10.2478/acve-2022-0038 . .