@conference{
author = "Milčić Matić, Natalija and Prošić, Isidora",
year = "2024",
abstract = "Canine otitis externa is a common dermatologic problem in
small animal practice. Affected ears are often painful and pruritic
often with an unpleasant smelling discharge. Canine otitis externa,
prevalent in 5% to 20% of dogs gl obally, is a common reason for
antibiotic prescriptions in small animal practice and raises concerns
as dogs may serve as potential reservoirs of antimicrobial resistance
(AMR) determinants, impacting public health. This study aimed to
determine the preval ence of various bacteria causing clinical ear
infections in dogs and describe the AMR patterns of the primary
causative agents of canine otitis. A total of 167 ear swabs were
collected from patients at the Dermatology Clinic at the Faculty of
Veterinary Me dicine in Belgrade, Serbia, between 2017 and 2023. 218
bacterial strains were isolated, with mixed infections detected in 50
(29.94%) samples. Additionally, 218 antibiograms were analyzed. From the 167 ear swabs, the most prevalent isolated species was
Staphylococcus pseudintermedius , found in 72 ear swabs (43.11%),
followed by Pseudomonas aeruginosa , isolated from 48 ear swabs
(28.74%). Proteus spp. accounted for 15.57%, Streptococcus spp. for
12.57%, S. aureus and coagulase negative staphylococci for 9 .58%
each, and Enterobacteriales (excluding Proteus spp.) for 4.79%. A
minimum of 12 antibiotic compounds from 9 antibiotic classes were
tested for each strain. Depending on the type of bacteria tested,
resistance ranged from 12.5% to 93.75% for penicillin s, 12.5% to
93.75% for cephalosporins, 12.5% to 52.77% for fluoroquinolones,
3.85% to 76.67% for aminoglycosides, 27.27% to 75% for macrolides,
0% to 78.72% for amphenicols, 22.22% to 95.5% for sulfonamides,
43.75% to 97.5% for tetracyclines, and 6.25% to 40% for imipenem.
Effective treatment of ear infection includes treatment of infection and
inflammatory changes as well as determination of the underlying
factors that led to development of otitis in the first place. Topical
therapy is the mainstay treatm ent for otitis externa although systemic
use of anti inflammatory therapy and/or antimicrobial therapy may
be indicated for individual patients. Many commercially available
topical ear medications contain a combination of antibiotics, antifungals, and gluc ocorticoids and are supplied in different
formulations for daily or weekly applications. Common antibiotics
are aminoglycosides (gentamicin, neomycin), fluoroquinolones
(ciprofloxacin, enrofloxacin, marbofloxacin), polymyxin B, fusidic
acid and florfenicol . Considering the small number of topical
antibiotics available, and the relatively high resistance of bacteria
diagnosed in the ear canal, in some cases we have to apply
antisepticsor injectable antibiotics in different concentrations.
Continued surveill ance is vital to grasp antimicrobial resistance
trends in veterinary medicine. This study underscores the necessity of
establishing an antimicrobial resistance surveillance program in small
animal practice, especially with the rising number of pet owners.
Regular monitoring is crucial for understanding and addressing
antimicrobial resistance in companion animals, particularly in Serbia,
where surveillance programs are lacking despite global
recommendations.",
publisher = "Novi Sad : Faculty of Agriculture",
journal = "3 rd International Conference Antimicrobial Resistance - Current State and Perspectives, Novi Sad, 16 - 18. maj, 2024",
title = "Do we need new drugs in therapy of otitis externa, or the old ones still works?",
pages = "129-131",
url = "https://hdl.handle.net/21.15107/rcub_veterinar_4025"
}
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