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Genotoxicity potential of 8-Cl-cyclic adenosine monophosphate assessed with cytogenetic tests in vivo
(Elsevier Science Inc, New York, 2004)
Background. Growth-modulating noncytotoxic activity of 8-chloro-adenosine 3,5-cyclic monophosphate (8-Cl-cAMP) showed inhibitory effect on growth of a wide variety of cancer cell lines in vitro and in vivo. To assess ...
Analysis of premature centromere division (PCD) of the X chromosome in Alzheimer patients through the cell cycle
(Pergamon-Elsevier Science Ltd, Oxford, 2004)
Cytogenetic analysis of the X chromosome in phytohaemagglutinin stimulated peripheral blood lymphocytes was evaluated in 12 sporadic Alzheimer disease (AD) patients and in 11 healthy subjects. For chromosome analysis two ...
Analysis of sister-chromatid exchanges and micronuclei in cultured human lymphocytes treated with insulin
(Charles Univ Prague, First Faculty Medicine, Prague 6, 2001)
Insulin is an anabolic hormone that may facilitate development of malignant diseases in various susceptible tissues due to stimulation of mitotic divisions. In this work, an evaluation of mitogenic and genotoxic effects ...
Guaianolides from two subspecies of Amphoricarpos neumayeri from Montenegro
(Pergamon-Elsevier Science Ltd, Oxford, 2004)
Quantitative H-1 NMR measurements revealed Delta(11(13)) sesquiterpene gamma-lactones as the main constituents (greater than or equal to 1% per weight of dried plant material) in the crude extracts of the aerial parts of ...
Combined effects of plant extracts and xenobiotics on liposomal lipid peroxidation. Part 4. Dandelion extract - Ciprofloxacin/pyralene
(Scibulcom Ltd, Sofia, 2001)
The article describes a study of the protective effect of dandelion (Taraxacum officinale L. Asteraceae) in combination with two xenobiotics: ciprofloxacin and pyralene. For that purpose, methanolic extracts of the plant ...
Antioxidant status of patients with acute myocardial infarction
(Dustri-Verlag Dr Karl Feistle, Deisenhofen-Muenchen, 2003)
Objectives: It has been suggested that dietary selenium (Se) deficiency is implicated in the etiology of cardiovascular disease. In this study, we examined the antioxidant status of patients with acute myocardial infarction ...
Xylazine, an alpha(2)-adrenergic agonist, induces apoptosis of rat thymocytes and a thymocyte hybridoma line in vitro
(Prous Science, Sau-Thomson Reuters, Barcelona, 2003)
In our previous experiments, we demonstrated that xylazine, an alpha(2)-adrenergic agonist, stimulated proliferation of thymocytes triggered by concanavalin A. In contrast, higher concentrations of xylazine were inhibitory. ...
Xylazine, an alpha(2)-adrenergic agonist, modulates proliferation of rat thymocytes in vivo and in vitro
(Prous Science, Sau-Thomson Reuters, Barcelona, 2000)
The effect of xylazine, an alpha (2)-adrenergic agonist, on proliferation of rat thymocytes in vivo and in vitro was examined. It was found that the agonist administered to rats in vivo at doses of 2.5 mg/kg and 5 mg/kg ...
Supercritical carbon dioxide extraction of carrot fruit essential oil: Chemical composition and antimicrobial activity
(Elsevier Sci Ltd, Oxford, 2007)
Isolation of carrot fruit (Daucus carrota L., cultivar Chanteney) essential oil by supercritical carbon dioxide was investigated from the pretreatment of herbaceous matrix and extraction conditions to the chemical composition ...
Evaluation of genotoxic effects of fumagillin by cytogenetic tests in vivo
(Elsevier Science Bv, Amsterdam, 2007)
Fumagillin is a naturally secreted antibiotic of the fungus Aspergillus fumigates. It is used in veterinary medicine against microsporidiosis of bees and fish. In this study, the genotoxicity of fumagillin (in the form of ...