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Prikaz rezultata 1-10 od 16
Genotoxicity potential of 8-Cl-cyclic adenosine monophosphate assessed with cytogenetic tests in vivo
(Elsevier Science Inc, New York, 2004)
Background. Growth-modulating noncytotoxic activity of 8-chloro-adenosine 3,5-cyclic monophosphate (8-Cl-cAMP) showed inhibitory effect on growth of a wide variety of cancer cell lines in vitro and in vivo. To assess ...
The effect of different acute concentrations of cadmium chloride on the frequency of micronuclei in AO rats / Efekat različitih akutnih koncentracija kadmijum-hlorida na učestalost mikronukleusa kod pacova AO soja
(Društvo genetičara Srbije, Beograd, 2013)
Cadmium (Cd) is highly toxic heavy metal which may cause severe biological effects in vivo and in vitro. In this study, an evaluation of the acute Cd ability to trigger micronuclei (MNi) formation was carried out on ...
Genotoxicity of the anticoccidial agent salinomycin
(Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd, 1998)
This report presents an analysis of genotoxic effects of the ionophoric antibiotic salinomycin commonly used in the control of coccidiosis. Mutagenic properties were determined, after application of increasing doses to ...
Fumagillin-induced chromosome aberrations in mouse bone-marrow cells / Hromozomske aberacije prouzrokovane fumagilinom u ćelijama kostne srži miša
(Srpsko biološko društvo, Beograd, i dr., 2010)
The genotoxicity of fumagillin was evaluated assessing the mitotic index and chromosome aberrations in mouse bone-marrow cells. Mice were given fumagillin orally in doses 5, 10 and 20 mg/kg bw. All doses significantly (p ...
Analysis of sister-chromatid exchanges in cultured human lymphocytes treated with cymiazole hydrochloride / Analiza razmene sestrinskih hromatida u kulturama limfocita čoveka tretiranih cimiazol hidrohloridom
(Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd, 2003)
Cymiazole hydrochloride is the active component of the acaricides Apitol® and Apichem®, which are used as varroacides in beekeeping. Considering that residues of cymiazole hydrochloride were detected in all bee products ...
Cytogenetic analysis of the effects of epinephrine on cultured human lymphocytes / Citogenetička analiza dejstva adrenalina na humane limfocite u kulturi
(Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd, 2003)
Epinephrine can modulate mitotic activity of normal and malignant cells and exhibit genotoxic potential in some test-systems. It is assumed that metabolic conversion of phenolic groups in the catechol ring of epinephrine ...
Monitoring of mitotic index and frequency of micronuclei in evaluation of genotoxic potential of fumagillin (dicyclohexylamine) in vivo / Praćenje mitotskog indeksa i učestalosti mikronukleusa u funkciji procene genotoksičnog potencijala fumagilina (dicikloheksilamina) in vivo
(Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd, 2006)
Fumagillin (dicyclohexylamine) is a natural antibiotic, secreted by Aspergillus fumigatus. It is used in veterinary medicine against microsporidiosis in bees and fish, as well as in human medicine for the treatment of ...
Frequency of chromosomal aberrations in the evaluation of genotoxic potential of dicyclohexylamine (fumagillin) in vivo / Učestalost hromozomskih aberacija u funkciji evaluacije genotoksičnog potencijala fumagilina in vivo
(Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd, 2006)
Dicyclohexylamine (fumagillin), as an antibiotic produced by fermentation of Aspergillus fumigatus, is used in human medicine for the treatment of intestinal microsporidiosis in patients with HIV infection, intestinal ...
Assessment of adrenaline-induced DNA damage in whole blood cells with the comet assay
(Inst Medical Research & Occupational Health, Zagreb, 2018)
Harmful effects of elevated levels of catecholamines are mediated by various mechanisms, including gene transcription and formation of oxidation products. The aim of this study was to see whether the molecular mechanisms ...
Enhanced sister-chromatid exchange rate in human lymphocytes exposed to 17 beta estradiol in vitro
(Elsevier Science Inc, New York, 2002)
Background. Epidemiologic data and animal experiments strongly implicate that steroid hormones are involved in the process of malignant transformation due to their capability to stimulate mitotic division and/or elevate ...