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Now showing items 11-16 of 16
Frequency of chromosomal aberrations in the evaluation of genotoxic potential of dicyclohexylamine (fumagillin) in vivo / Učestalost hromozomskih aberacija u funkciji evaluacije genotoksičnog potencijala fumagilina in vivo
(Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd, 2006)
Dicyclohexylamine (fumagillin), as an antibiotic produced by fermentation of Aspergillus fumigatus, is used in human medicine for the treatment of intestinal microsporidiosis in patients with HIV infection, intestinal ...
Enhanced sister-chromatid exchange rate in human lymphocytes exposed to 17 beta estradiol in vitro
(Elsevier Science Inc, New York, 2002)
Background. Epidemiologic data and animal experiments strongly implicate that steroid hormones are involved in the process of malignant transformation due to their capability to stimulate mitotic division and/or elevate ...
Examination of 8-CI-cAMP genotoxicity by two in vivo test in BALB/c strain mice / Ispitivanje genotoksičnosti 8-CI-cAMP u dva in vivo testa na miševima soja BALB/c
(Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd, 2000)
The antitumor agent 8-CI-cAMP (8-chloro-cyclic adenosine monophosphate) is the most potent site-selective analogue of cAMP. It acts primarily by selective down-regulation of regulatory sub-units of cAMP-dependent protein ...
Examination of genotoxic effects of fumagillin in vivo / Ispitivanje genotoksicnih efekata fumagillina in vivo
(Društvo genetičara Srbije, Beograd, 2009)
Fumagillin is an antibiotic derived from the fungus Aspergillus fumigatus. It has been used successfully for the treatment of intestinal microsporidiosis in HIV-positive humans, as well as in those suffering from intestinal ...
Cytogenetic analysis of the effects of epinephrine on cultured human lymphocytes / Citogenetička analiza dejstva adrenalina na humane limfocite u kulturi
(Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd, 2003)
Epinephrine can modulate mitotic activity of normal and malignant cells and exhibit genotoxic potential in some test-systems. It is assumed that metabolic conversion of phenolic groups in the catechol ring of epinephrine ...
Evaluation of the genotoxic effects of thyroxine using in vivo cytogenetic test on Swiss albino mice / Evaluacija genotoksičnih efekata tiroksina primenom in vivo citogenetičkog testa na Swiss albino miševima
(Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd, 2007)
Thyroid hormones enhance aerobic metabolism favoring oxidative stress which may lead to covalent damage of various molecules including DNA. Previous investigations revealed that thyroid hormones induce DNA damage on human ...