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Analysis of sister-chromatid exchanges and micronuclei in cultured human lymphocytes treated with insulin
(Charles Univ Prague, First Faculty Medicine, Prague 6, 2001)
Insulin is an anabolic hormone that may facilitate development of malignant diseases in various susceptible tissues due to stimulation of mitotic divisions. In this work, an evaluation of mitogenic and genotoxic effects ...
Mutagenic activity of estradiol evaluated by an in vitro micronucleus assay - Short communication
(Akademiai Kiado, Budapest, 2005)
The objective of the present study was to evaluate possible genetic changes in cultured human lymphocytes treated with estradiol, using the cytokinesis block micronucleus assay. Eight experimental concentrations of estradiol ...
Genotoxicity potential of 8-Cl-cyclic adenosine monophosphate assessed with cytogenetic tests in vivo
(Elsevier Science Inc, New York, 2004)
Background. Growth-modulating noncytotoxic activity of 8-chloro-adenosine 3,5-cyclic monophosphate (8-Cl-cAMP) showed inhibitory effect on growth of a wide variety of cancer cell lines in vitro and in vivo. To assess ...
Analysis of premature centromere division (PCD) of the X chromosome in Alzheimer patients through the cell cycle
(Pergamon-Elsevier Science Ltd, Oxford, 2004)
Cytogenetic analysis of the X chromosome in phytohaemagglutinin stimulated peripheral blood lymphocytes was evaluated in 12 sporadic Alzheimer disease (AD) patients and in 11 healthy subjects. For chromosome analysis two ...
Antioxidant status of patients with acute myocardial infarction
(Dustri-Verlag Dr Karl Feistle, Deisenhofen-Muenchen, 2003)
Objectives: It has been suggested that dietary selenium (Se) deficiency is implicated in the etiology of cardiovascular disease. In this study, we examined the antioxidant status of patients with acute myocardial infarction ...
Supercritical carbon dioxide extraction of carrot fruit essential oil: Chemical composition and antimicrobial activity
(Elsevier Sci Ltd, Oxford, 2007)
Isolation of carrot fruit (Daucus carrota L., cultivar Chanteney) essential oil by supercritical carbon dioxide was investigated from the pretreatment of herbaceous matrix and extraction conditions to the chemical composition ...
Combined effects of plant extracts and xenobiotics on liposomal lipid peroxidation. Part 4. Dandelion extract - Ciprofloxacin/pyralene
(Scibulcom Ltd, Sofia, 2001)
The article describes a study of the protective effect of dandelion (Taraxacum officinale L. Asteraceae) in combination with two xenobiotics: ciprofloxacin and pyralene. For that purpose, methanolic extracts of the plant ...
Xylazine, an alpha(2)-adrenergic agonist, induces apoptosis of rat thymocytes and a thymocyte hybridoma line in vitro
(Prous Science, Sau-Thomson Reuters, Barcelona, 2003)
In our previous experiments, we demonstrated that xylazine, an alpha(2)-adrenergic agonist, stimulated proliferation of thymocytes triggered by concanavalin A. In contrast, higher concentrations of xylazine were inhibitory. ...
The effect of the antioxidant catalase on oestrogens, triiodothyronine, and noradrenaline in the Comet assay.
(Teratogenesis, carcinogenesis, and mutagenesis, 2003)
Metabolic changes in the phenolic groups of steroidal oestrogens accompanied by the generation of quinones and reactive oxygen species underlie their mutagenic effects. Although nonsteroidal hormones and related compounds ...
Ground red hot pepper agar in the isolation and presumptive identification of Cryptococcus neoformans
(Wiley, Hoboken, 2002)
The study compared ground red hot pepper agar (GRHP) and Guzzotia abyssinica creatinine agar (GACA), a medium routinely used for isolation of Cryptococcus neoformans. In order to confirm the capacity of GRHP to support the ...