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Genotoxicity potential of 8-Cl-cyclic adenosine monophosphate assessed with cytogenetic tests in vivo
(Elsevier Science Inc, New York, 2004)
Background. Growth-modulating noncytotoxic activity of 8-chloro-adenosine 3,5-cyclic monophosphate (8-Cl-cAMP) showed inhibitory effect on growth of a wide variety of cancer cell lines in vitro and in vivo. To assess ...
Effects of photopolymerisation on genotoxicity of composite adhesives in the comet assay
(Društvo genetičara Srbije, Beograd, 2016)
Certain in vivo studies have shown that the application of adhesives directly onto the open pulp or on a thin layer of dentin causes inflammation and pulpal abscesses. This reaction is related to toxic effects of monomers ...
Examination of Carbadox genotoxicity in vitro and in vivo / Ispitivanje genotoksičnog efekta Carbadoxa in vitro i in vivo
(Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd, 2000)
Due to its bactericidal activity Carbadox is used for treatment of swine dysentery and salmonellosis. Also, it can be used as a factor for growth stimulation. Carbadox is the only drug for certain health problems in swine ...
Genotoxicity of the anticoccidial agent salinomycin
(Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd, 1998)
This report presents an analysis of genotoxic effects of the ionophoric antibiotic salinomycin commonly used in the control of coccidiosis. Mutagenic properties were determined, after application of increasing doses to ...
Analysis of sister-chromatid exchanges in cultured human lymphocytes treated with cymiazole hydrochloride / Analiza razmene sestrinskih hromatida u kulturama limfocita čoveka tretiranih cimiazol hidrohloridom
(Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd, 2003)
Cymiazole hydrochloride is the active component of the acaricides Apitol® and Apichem®, which are used as varroacides in beekeeping. Considering that residues of cymiazole hydrochloride were detected in all bee products ...
Enhanced sister-chromatid exchange rate in human lymphocytes exposed to 17 beta estradiol in vitro
(Elsevier Science Inc, New York, 2002)
Background. Epidemiologic data and animal experiments strongly implicate that steroid hormones are involved in the process of malignant transformation due to their capability to stimulate mitotic division and/or elevate ...
Assessment of adrenaline-induced DNA damage in whole blood cells with the comet assay
(Inst Medical Research & Occupational Health, Zagreb, 2018)
Harmful effects of elevated levels of catecholamines are mediated by various mechanisms, including gene transcription and formation of oxidation products. The aim of this study was to see whether the molecular mechanisms ...
Fumagillin-induced chromosome aberrations in mouse bone-marrow cells / Hromozomske aberacije prouzrokovane fumagilinom u ćelijama kostne srži miša
(Srpsko biološko društvo, Beograd, i dr., 2010)
The genotoxicity of fumagillin was evaluated assessing the mitotic index and chromosome aberrations in mouse bone-marrow cells. Mice were given fumagillin orally in doses 5, 10 and 20 mg/kg bw. All doses significantly (p ...
The effect of different acute concentrations of cadmium chloride on the frequency of micronuclei in AO rats / Efekat različitih akutnih koncentracija kadmijum-hlorida na učestalost mikronukleusa kod pacova AO soja
(Društvo genetičara Srbije, Beograd, 2013)
Cadmium (Cd) is highly toxic heavy metal which may cause severe biological effects in vivo and in vitro. In this study, an evaluation of the acute Cd ability to trigger micronuclei (MNi) formation was carried out on ...
Monitoring of mitotic index and frequency of micronuclei in evaluation of genotoxic potential of fumagillin (dicyclohexylamine) in vivo / Praćenje mitotskog indeksa i učestalosti mikronukleusa u funkciji procene genotoksičnog potencijala fumagilina (dicikloheksilamina) in vivo
(Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd, 2006)
Fumagillin (dicyclohexylamine) is a natural antibiotic, secreted by Aspergillus fumigatus. It is used in veterinary medicine against microsporidiosis in bees and fish, as well as in human medicine for the treatment of ...