Milićević, Dragan

Link to this page

Authority KeyName Variants
orcid::0000-0001-9001-0584
  • Milićević, Dragan (14)
Projects
Ministry of Education, Science and Technological Development, Republic of Serbia, Grant no. 451-03-68/2020-14/200143 (University of Belgrade, Faculty of Veterinary Medicine) Improvement and development of hygienic and technological procedures in production of animal originating foodstuffs with the aim of producing high-quality and safe products competetive on the global market
Development of herbal medicines and biocides on the basis of Carvacrol, Thymol and Cinnamaldehyde for use in veterinary medicine, animal husbandry and food production without harmful residues Ministry of Education, Science and Technological Development, Republic of Serbia, Grant no. 451-03-68/2020-14/200050 (Institute of Meat Hygiene and Technology, Belgrade)
Molecular genetic and ecophysiological researches on the protection of autochthonous animal genetic resources, sustaining domestic animals’ welfare, health and reproduction, and safe food production Development of technologies and products based on mineral raw materials and waste biomass for protection of natural resources for safe food production
Development and application of molecular methods based on polymerase chain reaction (PCR) in rapid and direct identification of Newcastle disease virus strains and examination of immunogenicity of subunit vaccine prepared from their antigens Development of technological processes for obtaining of ecological materials based on nonmetallic minerals
Ministry of Education, Sciences and Technological Developments of Republic Serbia

Author's Bibliography

Efficacy of a Modified Clinoptilolite Based Adsorbent in Reducing Detrimental Effects of Ochratoxin A in Laying Hens

Vasiljević, Marko; Marinković, Darko; Milićević, Dragan; Pleadin, Jelka; Stefanović, Srđan; Trialović, Saša; Raj, Jog; Petrujkić, Branko; Trialović, Jelena Nedejković

(MDPI, 2021)

TY  - JOUR
AU  - Vasiljević, Marko
AU  - Marinković, Darko
AU  - Milićević, Dragan
AU  - Pleadin, Jelka
AU  - Stefanović, Srđan
AU  - Trialović, Saša
AU  - Raj, Jog
AU  - Petrujkić, Branko
AU  - Trialović, Jelena Nedejković
PY  - 2021
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/2230
PB  - MDPI
T2  - Toxins
T1  - Efficacy of a Modified Clinoptilolite Based Adsorbent in Reducing Detrimental Effects of Ochratoxin A in Laying Hens
VL  - 13
IS  - 7
SP  - 469
DO  - 10.3390/toxins13070469
ER  - 
@article{
author = "Vasiljević, Marko and Marinković, Darko and Milićević, Dragan and Pleadin, Jelka and Stefanović, Srđan and Trialović, Saša and Raj, Jog and Petrujkić, Branko and Trialović, Jelena Nedejković",
year = "2021",
publisher = "MDPI",
journal = "Toxins",
title = "Efficacy of a Modified Clinoptilolite Based Adsorbent in Reducing Detrimental Effects of Ochratoxin A in Laying Hens",
volume = "13",
number = "7",
pages = "469",
doi = "10.3390/toxins13070469"
}
Vasiljević, M., Marinković, D., Milićević, D., Pleadin, J., Stefanović, S., Trialović, S., Raj, J., Petrujkić, B.,& Trialović, J. N.. (2021). Efficacy of a Modified Clinoptilolite Based Adsorbent in Reducing Detrimental Effects of Ochratoxin A in Laying Hens. in Toxins
MDPI., 13(7), 469.
https://doi.org/10.3390/toxins13070469
Vasiljević M, Marinković D, Milićević D, Pleadin J, Stefanović S, Trialović S, Raj J, Petrujkić B, Trialović JN. Efficacy of a Modified Clinoptilolite Based Adsorbent in Reducing Detrimental Effects of Ochratoxin A in Laying Hens. in Toxins. 2021;13(7):469.
doi:10.3390/toxins13070469 .
Vasiljević, Marko, Marinković, Darko, Milićević, Dragan, Pleadin, Jelka, Stefanović, Srđan, Trialović, Saša, Raj, Jog, Petrujkić, Branko, Trialović, Jelena Nedejković, "Efficacy of a Modified Clinoptilolite Based Adsorbent in Reducing Detrimental Effects of Ochratoxin A in Laying Hens" in Toxins, 13, no. 7 (2021):469,
https://doi.org/10.3390/toxins13070469 . .
3
10
8

Genetic analysis and distribution of porcine parvoviruses detected in the organs of wild boars in Serbia

Nišavić, Jakov; Milić, Nenad; Radalj, Andrea; Krnjaić, Dejan; Milićević, Dragan; Knežević, Aleksandra; Radojičić, Marina; Obrenović, Sonja; Ćosić, Milivoje; Tešović, Bojana; Benković, Damir; Živulj Aleksandar

(Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd, 2021)

TY  - JOUR
AU  - Nišavić, Jakov
AU  - Milić, Nenad
AU  - Radalj, Andrea
AU  - Krnjaić, Dejan
AU  - Milićević, Dragan
AU  - Knežević, Aleksandra
AU  - Radojičić, Marina
AU  - Obrenović, Sonja
AU  - Ćosić, Milivoje
AU  - Tešović, Bojana
AU  - Benković, Damir
AU  - Živulj Aleksandar
PY  - 2021
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/2044
AB  - Porcine parvoviruses (PPVs) are diverse and persistently evolving viruses found in domestic pigs and wild boars. Porcine parvovirus 1 (PPV1) causes reproductive problems in adult animals, although the veterinary relevance of PPV2, PPV3, and PPV4 has not been clarified. The detection and sequence analysis of PPVs circulating in wild boar populations in Serbia was performed to determine their phylogenetic relationships and prevalence in 122 organ samples collected during 2018. The DNA of PPV1, PPV2, and PPV3 was detected in 56.6% of the examined samples, whilst PPV4 was not identified. Overall, PPV3 was the most prevalent in 69.6% of the positive samples, followed by PPV1 in 63.8%, and PPV2 in 21.7% samples. Single infections were more common, although concurrent infections were confirmed in 34.8% samples for two, and 10.1% samples for three viruses. Sequence analysis of wild boar PPV1 showed no significant nucleotide differences from domestic pig PPV1 strains detected in Europe and the USA, however separate clustering from strains from China and the NADL-2 strain was demonstrated. Examination of the selected PPV2 sequences might suggest a certain geographical distribution of genetically diverse PPV2 strains considering high similarities to the strains from neighboring countries, and variability in comparison with other reported PPV2 sequences from different parts of the world. Wild boar PPV3 sequences clustered separately from most of the strains detected in wild boars, as well as the original porcine hokovirus strain. It is further noted that genetically different PPV3 strains circulate amongst Serbian domestic pigs and wild boars.
AB  - Parvovirusi svinja predstavljaju genetski različite viruse koji izazivaju infekcije doma-ćih i divljih svinja. Parvovirus svinja 1 (PPV1) dovodi do pojave reproduktivnih pro-blema  kod  odraslih  jedinki,  dok  klinički  značaj  PPV2,  PPV3  i  PPV4  još  uvek  nije  u  potpunosti  razjašnjen.  Izvršena  je  detekcija  i  analiza  genetskih  sekvenci  parvovirusa  koji  cirkulišu  u  populaciji  divljih  svinja  u  Srbiji  u  cilju  njihove  fi  logenetske  analize  i  određivanja zastupljenosti u ukupno 122 uzorka organa prikupljenih tokom 2018. go-dine. Prisustvo DNK PPV1, PPV2 i PPV3 detektovano je u 56,6% ispitanih uzoraka, pri čemu  prisustvo  PPV4  nije  utvrđeno.  Među  pozitivnim  uzorcima,  PPV3  je  pro-centualno najzastupljeniji virus detektovan u 69,6%, dok je prisustvo  PPV1 i PPV2 utvrđeno u 63,8%, odnosno u 21,7% pozitivnih uzoraka. Infekcije jednim virusom su češće identifi kovane, međutim, prisustvo mešovitih infekcija sa dva, odnosno tri par-vovirusa zabeleženo je u 34,8% i 10,1% uzoraka. Analizom genetskih sekvenci PPV1 detektovanih kod divljih svinja nisu utvrđene značajnije razlike u odnosu na analogne sekvence PPV1 poreklom od domaćih svinja iz Evrope i SAD, međutim zabeleženo je izdvajanje u zaseban klaster u odnosu na kineske sojeve virusa i soj NADL-2. Ispi-tivanjem sekvenci PPV2 utvrđena je izvesna geografska distribucija genetski različitih sojeva navedenog virusa s obzirom na njihovu veliku sličnost sa sojevima virusa iz su-sednih zemalja. Sekvence PPV3 detektovanih kod divljih svinja su se na fi logenetskom stablu izdvajale u zaseban klaster u odnosu na većinu dostupnih sekvenci navedenog virusa detektovanih kod divljih svinja. Pored toga, zabeleženo je da genetski različiti sojevi PPV3 cirkulišu u populacijama divljih i domaćih svinja u Srbiji.
PB  - Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd
T2  - Acta Veterinaria-Beograd
T1  - Genetic analysis and distribution of porcine parvoviruses detected in the organs of wild boars in Serbia
T1  - Genetska analiza i distribucija parvovirusa (ppvs) detektovanih u organima divljih svinja u Srbiji
VL  - 71
IS  - 1
SP  - 32
EP  - 46
DO  - 10.2478/acve-2021-0003
ER  - 
@article{
author = "Nišavić, Jakov and Milić, Nenad and Radalj, Andrea and Krnjaić, Dejan and Milićević, Dragan and Knežević, Aleksandra and Radojičić, Marina and Obrenović, Sonja and Ćosić, Milivoje and Tešović, Bojana and Benković, Damir and Živulj Aleksandar",
year = "2021",
abstract = "Porcine parvoviruses (PPVs) are diverse and persistently evolving viruses found in domestic pigs and wild boars. Porcine parvovirus 1 (PPV1) causes reproductive problems in adult animals, although the veterinary relevance of PPV2, PPV3, and PPV4 has not been clarified. The detection and sequence analysis of PPVs circulating in wild boar populations in Serbia was performed to determine their phylogenetic relationships and prevalence in 122 organ samples collected during 2018. The DNA of PPV1, PPV2, and PPV3 was detected in 56.6% of the examined samples, whilst PPV4 was not identified. Overall, PPV3 was the most prevalent in 69.6% of the positive samples, followed by PPV1 in 63.8%, and PPV2 in 21.7% samples. Single infections were more common, although concurrent infections were confirmed in 34.8% samples for two, and 10.1% samples for three viruses. Sequence analysis of wild boar PPV1 showed no significant nucleotide differences from domestic pig PPV1 strains detected in Europe and the USA, however separate clustering from strains from China and the NADL-2 strain was demonstrated. Examination of the selected PPV2 sequences might suggest a certain geographical distribution of genetically diverse PPV2 strains considering high similarities to the strains from neighboring countries, and variability in comparison with other reported PPV2 sequences from different parts of the world. Wild boar PPV3 sequences clustered separately from most of the strains detected in wild boars, as well as the original porcine hokovirus strain. It is further noted that genetically different PPV3 strains circulate amongst Serbian domestic pigs and wild boars., Parvovirusi svinja predstavljaju genetski različite viruse koji izazivaju infekcije doma-ćih i divljih svinja. Parvovirus svinja 1 (PPV1) dovodi do pojave reproduktivnih pro-blema  kod  odraslih  jedinki,  dok  klinički  značaj  PPV2,  PPV3  i  PPV4  još  uvek  nije  u  potpunosti  razjašnjen.  Izvršena  je  detekcija  i  analiza  genetskih  sekvenci  parvovirusa  koji  cirkulišu  u  populaciji  divljih  svinja  u  Srbiji  u  cilju  njihove  fi  logenetske  analize  i  određivanja zastupljenosti u ukupno 122 uzorka organa prikupljenih tokom 2018. go-dine. Prisustvo DNK PPV1, PPV2 i PPV3 detektovano je u 56,6% ispitanih uzoraka, pri čemu  prisustvo  PPV4  nije  utvrđeno.  Među  pozitivnim  uzorcima,  PPV3  je  pro-centualno najzastupljeniji virus detektovan u 69,6%, dok je prisustvo  PPV1 i PPV2 utvrđeno u 63,8%, odnosno u 21,7% pozitivnih uzoraka. Infekcije jednim virusom su češće identifi kovane, međutim, prisustvo mešovitih infekcija sa dva, odnosno tri par-vovirusa zabeleženo je u 34,8% i 10,1% uzoraka. Analizom genetskih sekvenci PPV1 detektovanih kod divljih svinja nisu utvrđene značajnije razlike u odnosu na analogne sekvence PPV1 poreklom od domaćih svinja iz Evrope i SAD, međutim zabeleženo je izdvajanje u zaseban klaster u odnosu na kineske sojeve virusa i soj NADL-2. Ispi-tivanjem sekvenci PPV2 utvrđena je izvesna geografska distribucija genetski različitih sojeva navedenog virusa s obzirom na njihovu veliku sličnost sa sojevima virusa iz su-sednih zemalja. Sekvence PPV3 detektovanih kod divljih svinja su se na fi logenetskom stablu izdvajale u zaseban klaster u odnosu na većinu dostupnih sekvenci navedenog virusa detektovanih kod divljih svinja. Pored toga, zabeleženo je da genetski različiti sojevi PPV3 cirkulišu u populacijama divljih i domaćih svinja u Srbiji.",
publisher = "Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd",
journal = "Acta Veterinaria-Beograd",
title = "Genetic analysis and distribution of porcine parvoviruses detected in the organs of wild boars in Serbia, Genetska analiza i distribucija parvovirusa (ppvs) detektovanih u organima divljih svinja u Srbiji",
volume = "71",
number = "1",
pages = "32-46",
doi = "10.2478/acve-2021-0003"
}
Nišavić, J., Milić, N., Radalj, A., Krnjaić, D., Milićević, D., Knežević, A., Radojičić, M., Obrenović, S., Ćosić, M., Tešović, B., Benković, D.,& Živulj Aleksandar. (2021). Genetic analysis and distribution of porcine parvoviruses detected in the organs of wild boars in Serbia. in Acta Veterinaria-Beograd
Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd., 71(1), 32-46.
https://doi.org/10.2478/acve-2021-0003
Nišavić J, Milić N, Radalj A, Krnjaić D, Milićević D, Knežević A, Radojičić M, Obrenović S, Ćosić M, Tešović B, Benković D, Živulj Aleksandar. Genetic analysis and distribution of porcine parvoviruses detected in the organs of wild boars in Serbia. in Acta Veterinaria-Beograd. 2021;71(1):32-46.
doi:10.2478/acve-2021-0003 .
Nišavić, Jakov, Milić, Nenad, Radalj, Andrea, Krnjaić, Dejan, Milićević, Dragan, Knežević, Aleksandra, Radojičić, Marina, Obrenović, Sonja, Ćosić, Milivoje, Tešović, Bojana, Benković, Damir, Živulj Aleksandar, "Genetic analysis and distribution of porcine parvoviruses detected in the organs of wild boars in Serbia" in Acta Veterinaria-Beograd, 71, no. 1 (2021):32-46,
https://doi.org/10.2478/acve-2021-0003 . .
1
1

Presence of natural radionuclides and toxic elements in monocalcium phosphate, complete feed and pig manure

Vranješ, Borjana; Milićević, Dragan; Šefer, Dragan; Stefanović, Srđan; Ajtić, Jelena; Mitrović, Branislava

(Elsevier, Amsterdam, 2020)

TY  - JOUR
AU  - Vranješ, Borjana
AU  - Milićević, Dragan
AU  - Šefer, Dragan
AU  - Stefanović, Srđan
AU  - Ajtić, Jelena
AU  - Mitrović, Branislava
PY  - 2020
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/1809
AB  - Naturally occurring radionuclides and toxic elements are ubiquitous in the environment and can pose a great risk to animals health. Control of these toxic substances in animal diet is essential for animals welfare, human nutrition risk management as well as environmental protection. Our study addresses these issues by determining a content of natural radionuclides (K-40, U-238 and Ra-226), and toxic elements (Cd, Cr, As) in total of 108 samples: 36 monocalcium phosphate, 36 complete feed and 36 pig manure samples that were collected from 6 different commercial farms in the Republic of Serbia. In monocalcium phosphate the content of K-40, U-238 and Ra-226 ranged from 7.6-23.4 Bq kg(-1), 13.2-1778 Bq kg(-1) and 3.6-13.5 Bq kg(-)1, respectively. In complete feed samples, 40K ranged from 170 to 306 Bq kg(-1), U-238 from minimum detectable activity (MDA) to 9.1 Bq kg(-1), and Ra-226 from MDA-5.5 Bq kg(-1), while in pig manure K-40 ranged from 146 to 531 Bq kg(-1), U-238 from MDA-30.1 Bq kg(-1), and Ra-226 from MDA-10 Bq kg(-1). The concentrations of Cd, Cr and As in monocalcium phosphate were 0.26-14.9 mg kg(-1), 10.3-497 mg kg(-1), and 4.2-5.5 mg kg(-1), respectively. In complete feed, the content of Cd, Cr and As ranged from minimum detectable concentration (MDC) - 0.78 mg kg-1, 0.30-7.41 mg kg(-1), and 0.09-0.31 mg kg(-1), respectively. In pig manure Cd, Cr and As ranged from 0.8-2.3 mg kg(-1), 2.3-22.2 mg kg(-1), and 0.51-5.45 mg kg(-1), respectively. The obtained results showed that Cd concentration inmonocalcium phosphate exceeded the maximum permissible legislative concentrations for phosphate additives. Monocalcium phosphate is the main source of U-238 and Cr in complete feed, while Cd derives from other sources. For that reason excessive use of monocalcium phosphate can lead to high levels of these pollutants in complete feed and consequently in manure.
PB  - Elsevier, Amsterdam
T2  - Science of The Total Environment
T1  - Presence of natural radionuclides and toxic elements in monocalcium phosphate, complete feed and pig manure
VL  - 720
SP  - 137578
DO  - 10.1016/j.scitotenv.2020.137578
ER  - 
@article{
author = "Vranješ, Borjana and Milićević, Dragan and Šefer, Dragan and Stefanović, Srđan and Ajtić, Jelena and Mitrović, Branislava",
year = "2020",
abstract = "Naturally occurring radionuclides and toxic elements are ubiquitous in the environment and can pose a great risk to animals health. Control of these toxic substances in animal diet is essential for animals welfare, human nutrition risk management as well as environmental protection. Our study addresses these issues by determining a content of natural radionuclides (K-40, U-238 and Ra-226), and toxic elements (Cd, Cr, As) in total of 108 samples: 36 monocalcium phosphate, 36 complete feed and 36 pig manure samples that were collected from 6 different commercial farms in the Republic of Serbia. In monocalcium phosphate the content of K-40, U-238 and Ra-226 ranged from 7.6-23.4 Bq kg(-1), 13.2-1778 Bq kg(-1) and 3.6-13.5 Bq kg(-)1, respectively. In complete feed samples, 40K ranged from 170 to 306 Bq kg(-1), U-238 from minimum detectable activity (MDA) to 9.1 Bq kg(-1), and Ra-226 from MDA-5.5 Bq kg(-1), while in pig manure K-40 ranged from 146 to 531 Bq kg(-1), U-238 from MDA-30.1 Bq kg(-1), and Ra-226 from MDA-10 Bq kg(-1). The concentrations of Cd, Cr and As in monocalcium phosphate were 0.26-14.9 mg kg(-1), 10.3-497 mg kg(-1), and 4.2-5.5 mg kg(-1), respectively. In complete feed, the content of Cd, Cr and As ranged from minimum detectable concentration (MDC) - 0.78 mg kg-1, 0.30-7.41 mg kg(-1), and 0.09-0.31 mg kg(-1), respectively. In pig manure Cd, Cr and As ranged from 0.8-2.3 mg kg(-1), 2.3-22.2 mg kg(-1), and 0.51-5.45 mg kg(-1), respectively. The obtained results showed that Cd concentration inmonocalcium phosphate exceeded the maximum permissible legislative concentrations for phosphate additives. Monocalcium phosphate is the main source of U-238 and Cr in complete feed, while Cd derives from other sources. For that reason excessive use of monocalcium phosphate can lead to high levels of these pollutants in complete feed and consequently in manure.",
publisher = "Elsevier, Amsterdam",
journal = "Science of The Total Environment",
title = "Presence of natural radionuclides and toxic elements in monocalcium phosphate, complete feed and pig manure",
volume = "720",
pages = "137578",
doi = "10.1016/j.scitotenv.2020.137578"
}
Vranješ, B., Milićević, D., Šefer, D., Stefanović, S., Ajtić, J.,& Mitrović, B.. (2020). Presence of natural radionuclides and toxic elements in monocalcium phosphate, complete feed and pig manure. in Science of The Total Environment
Elsevier, Amsterdam., 720, 137578.
https://doi.org/10.1016/j.scitotenv.2020.137578
Vranješ B, Milićević D, Šefer D, Stefanović S, Ajtić J, Mitrović B. Presence of natural radionuclides and toxic elements in monocalcium phosphate, complete feed and pig manure. in Science of The Total Environment. 2020;720:137578.
doi:10.1016/j.scitotenv.2020.137578 .
Vranješ, Borjana, Milićević, Dragan, Šefer, Dragan, Stefanović, Srđan, Ajtić, Jelena, Mitrović, Branislava, "Presence of natural radionuclides and toxic elements in monocalcium phosphate, complete feed and pig manure" in Science of The Total Environment, 720 (2020):137578,
https://doi.org/10.1016/j.scitotenv.2020.137578 . .
8
1
7

Current status of mycotoxin contamination of food and feeds and associated public health risk in Serbia

Milićević, Dragan; Udovički, Božidar; Petrović, Zoran; Janković, Saša; Radulović, Stamen; Gurinović, Mirjana; Rajković, Andreja

(Beograd : Institut za higijenu i tehnologiju mesa, 2020)

TY  - JOUR
AU  - Milićević, Dragan
AU  - Udovički, Božidar
AU  - Petrović, Zoran
AU  - Janković, Saša
AU  - Radulović, Stamen
AU  - Gurinović, Mirjana
AU  - Rajković, Andreja
PY  - 2020
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/2068
AB  - Mycotoxins are chemical hazards of microbiological origin, produced mainly by filamentous fungi during their secondary metabolism. The role of mycotoxins has been recognized in the aetiology of a number of diseases, particularly cancers that belong to non-communicable diseases (NCDs). The NCDs have a leading and growing contribution to preventable deaths and disability across the globe. The NCDs are known as chronic diseases, tend to be of long duration and are the result of a combination of genetic, physiological, environmental and behavioural factors. Following the increased interest in health effects caused by synergisms between natural and synthetic contaminants along the food chain, mycotoxin contamination will continue to be an area of concern for producers, manufacturers, regulatory agencies, researchers and consumers in the future. Considering that their presence in food depends strongly on climatic conditions, in Serbia, recent drought and then flooding confirmed that mycotoxins are one of the foodborne hazards most susceptible to climate change. In this article, we review key aspects of mycotoxin contamination of the food supply chain and attempt to highlight the latest trends and projections for mycotoxin reduction from a Serbian perspective.
AB  - Mikotoksini predstavljaju hemijski hazard mikorbiološkog porekla, proizvod sekundarnog metabolizma pretežno filamentoznih plesni. Značaj mikotoksina najčešće se vezuje za pojavu brojnih oboljenja kod ljudi i životinja, koja pripadaju grupi nezaraznih bolesti (eng. non-communicable diseases). Nezarazne bolesti, (npr. maligni tumori), vodeći su uzroci obolevanja, invalidnosti i prevremenog umiranja (pre 65. godine života) u svetu, a i u našoj sredini (eng. Disability Adjusted Life Years-DALY). Maligna oboljenja se karakterišu dužim vremenom trajanja i nastaju kao posledica interakcije mnogobrojnih faktora kao što su genetski, fiziološki status organizma, prirodno okruženje i biološkog odgovora čovekovog organizma. Sve veće interesovanje za sinergistički efekat sintetskih i prirodnih kontaminenata na zdravlje ljudi, ukazuje na to da kontaminacija mikotoksinima predstavlja idalje oblast od prioritetnog značaja za sve učesnike u lancu hrane. Uzimajući u obzir da kontaminacija hrane mikotoksinima prvenstveno zavisi od klimatskih faktora, ekstremne klimatske pojave kao što su suša i poplave poslednjih godina zabeležene u Srbiji, potvrđuju činjenicu da su mikotoksini jedan od hazarda u lancu hrane na koji klimatske promene imaju najveći uticaj. U ovom radu pokušali smo da analiziramo ključne faktore od značaja za kontaminaciju mikotoksinima, kao i da se ukaže na najnovije trendove i strategije u prevenciji štetnih efekata mikotoksina u lancu hrane, sagledavajući stanje i mogućnosti u Srbiji.
PB  - Beograd : Institut za higijenu i tehnologiju mesa
T2  - Meat Technology
T2  - Meat Technology
T1  - Current status of mycotoxin contamination of food and feeds and associated public health risk in Serbia
T1  - Aktuelna situacija kontaminacije hrane i hrane za životinje mikotoksinima sa osvrtom na javnozdravstveni rizik u Srbiji
VL  - 61
IS  - 1
SP  - 1
EP  - 36
DO  - 10.18485/meattech.2020.61.1.1
ER  - 
@article{
author = "Milićević, Dragan and Udovički, Božidar and Petrović, Zoran and Janković, Saša and Radulović, Stamen and Gurinović, Mirjana and Rajković, Andreja",
year = "2020",
abstract = "Mycotoxins are chemical hazards of microbiological origin, produced mainly by filamentous fungi during their secondary metabolism. The role of mycotoxins has been recognized in the aetiology of a number of diseases, particularly cancers that belong to non-communicable diseases (NCDs). The NCDs have a leading and growing contribution to preventable deaths and disability across the globe. The NCDs are known as chronic diseases, tend to be of long duration and are the result of a combination of genetic, physiological, environmental and behavioural factors. Following the increased interest in health effects caused by synergisms between natural and synthetic contaminants along the food chain, mycotoxin contamination will continue to be an area of concern for producers, manufacturers, regulatory agencies, researchers and consumers in the future. Considering that their presence in food depends strongly on climatic conditions, in Serbia, recent drought and then flooding confirmed that mycotoxins are one of the foodborne hazards most susceptible to climate change. In this article, we review key aspects of mycotoxin contamination of the food supply chain and attempt to highlight the latest trends and projections for mycotoxin reduction from a Serbian perspective., Mikotoksini predstavljaju hemijski hazard mikorbiološkog porekla, proizvod sekundarnog metabolizma pretežno filamentoznih plesni. Značaj mikotoksina najčešće se vezuje za pojavu brojnih oboljenja kod ljudi i životinja, koja pripadaju grupi nezaraznih bolesti (eng. non-communicable diseases). Nezarazne bolesti, (npr. maligni tumori), vodeći su uzroci obolevanja, invalidnosti i prevremenog umiranja (pre 65. godine života) u svetu, a i u našoj sredini (eng. Disability Adjusted Life Years-DALY). Maligna oboljenja se karakterišu dužim vremenom trajanja i nastaju kao posledica interakcije mnogobrojnih faktora kao što su genetski, fiziološki status organizma, prirodno okruženje i biološkog odgovora čovekovog organizma. Sve veće interesovanje za sinergistički efekat sintetskih i prirodnih kontaminenata na zdravlje ljudi, ukazuje na to da kontaminacija mikotoksinima predstavlja idalje oblast od prioritetnog značaja za sve učesnike u lancu hrane. Uzimajući u obzir da kontaminacija hrane mikotoksinima prvenstveno zavisi od klimatskih faktora, ekstremne klimatske pojave kao što su suša i poplave poslednjih godina zabeležene u Srbiji, potvrđuju činjenicu da su mikotoksini jedan od hazarda u lancu hrane na koji klimatske promene imaju najveći uticaj. U ovom radu pokušali smo da analiziramo ključne faktore od značaja za kontaminaciju mikotoksinima, kao i da se ukaže na najnovije trendove i strategije u prevenciji štetnih efekata mikotoksina u lancu hrane, sagledavajući stanje i mogućnosti u Srbiji.",
publisher = "Beograd : Institut za higijenu i tehnologiju mesa",
journal = "Meat Technology, Meat Technology",
title = "Current status of mycotoxin contamination of food and feeds and associated public health risk in Serbia, Aktuelna situacija kontaminacije hrane i hrane za životinje mikotoksinima sa osvrtom na javnozdravstveni rizik u Srbiji",
volume = "61",
number = "1",
pages = "1-36",
doi = "10.18485/meattech.2020.61.1.1"
}
Milićević, D., Udovički, B., Petrović, Z., Janković, S., Radulović, S., Gurinović, M.,& Rajković, A.. (2020). Current status of mycotoxin contamination of food and feeds and associated public health risk in Serbia. in Meat Technology
Beograd : Institut za higijenu i tehnologiju mesa., 61(1), 1-36.
https://doi.org/10.18485/meattech.2020.61.1.1
Milićević D, Udovički B, Petrović Z, Janković S, Radulović S, Gurinović M, Rajković A. Current status of mycotoxin contamination of food and feeds and associated public health risk in Serbia. in Meat Technology. 2020;61(1):1-36.
doi:10.18485/meattech.2020.61.1.1 .
Milićević, Dragan, Udovički, Božidar, Petrović, Zoran, Janković, Saša, Radulović, Stamen, Gurinović, Mirjana, Rajković, Andreja, "Current status of mycotoxin contamination of food and feeds and associated public health risk in Serbia" in Meat Technology, 61, no. 1 (2020):1-36,
https://doi.org/10.18485/meattech.2020.61.1.1 . .
3
7

Risk assessment and risk management of contaminants in the feed to food chain

Radulović, Stamen; Šefer, Dragan; Marković, Radmila; Lukić, M.; Nikolić, Aleksandra; Milićević, Dragan

(Iop Publishing Ltd, Bristol, 2019)

TY  - CONF
AU  - Radulović, Stamen
AU  - Šefer, Dragan
AU  - Marković, Radmila
AU  - Lukić, M.
AU  - Nikolić, Aleksandra
AU  - Milićević, Dragan
PY  - 2019
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/1691
AB  - In feed production processes, factories usually produce different mixtures within the same production line. Consequently, remainders of the first-produced feed can stay in the system and be mixed with the following feed charge. This type of transfer (carry-over) is unavoidable in the production systems currently used, and thus, non-medicated feed can be contaminated with veterinary drugs present in a previously manufactured charge of medicated feed. The carry-over of veterinary medicinal products is associated with the risk of residues remaining in the tissues of treated animals at the time of slaughter and poses a health hazard to consumers. Producing safe feed and food products is, first and foremost, a question of good management practices at each stage of the feed and food chain, from primary production to final processing. Primary responsibility for feed safety rests with the feed business operator, who must ensure that all stages of production, processing and distribution under their control are carried out in accordance with relevant legislation, good manufacturing practice and principles contained in the HACCP system. Concrete steps for feed manufacturers to prevent drug carry-over are using one or more approved cleanout procedures of manufacturing equipment, such as cleaning, flushing or sequencing.
PB  - Iop Publishing Ltd, Bristol
C3  - 60th International Meat Industry Conference (MEATCON2019)
T1  - Risk assessment and risk management of contaminants in the feed to food chain
VL  - 333
SP  - UNSP 012030
DO  - 10.1088/1755-1315/333/1/012030
ER  - 
@conference{
author = "Radulović, Stamen and Šefer, Dragan and Marković, Radmila and Lukić, M. and Nikolić, Aleksandra and Milićević, Dragan",
year = "2019",
abstract = "In feed production processes, factories usually produce different mixtures within the same production line. Consequently, remainders of the first-produced feed can stay in the system and be mixed with the following feed charge. This type of transfer (carry-over) is unavoidable in the production systems currently used, and thus, non-medicated feed can be contaminated with veterinary drugs present in a previously manufactured charge of medicated feed. The carry-over of veterinary medicinal products is associated with the risk of residues remaining in the tissues of treated animals at the time of slaughter and poses a health hazard to consumers. Producing safe feed and food products is, first and foremost, a question of good management practices at each stage of the feed and food chain, from primary production to final processing. Primary responsibility for feed safety rests with the feed business operator, who must ensure that all stages of production, processing and distribution under their control are carried out in accordance with relevant legislation, good manufacturing practice and principles contained in the HACCP system. Concrete steps for feed manufacturers to prevent drug carry-over are using one or more approved cleanout procedures of manufacturing equipment, such as cleaning, flushing or sequencing.",
publisher = "Iop Publishing Ltd, Bristol",
journal = "60th International Meat Industry Conference (MEATCON2019)",
title = "Risk assessment and risk management of contaminants in the feed to food chain",
volume = "333",
pages = "UNSP 012030",
doi = "10.1088/1755-1315/333/1/012030"
}
Radulović, S., Šefer, D., Marković, R., Lukić, M., Nikolić, A.,& Milićević, D.. (2019). Risk assessment and risk management of contaminants in the feed to food chain. in 60th International Meat Industry Conference (MEATCON2019)
Iop Publishing Ltd, Bristol., 333, UNSP 012030.
https://doi.org/10.1088/1755-1315/333/1/012030
Radulović S, Šefer D, Marković R, Lukić M, Nikolić A, Milićević D. Risk assessment and risk management of contaminants in the feed to food chain. in 60th International Meat Industry Conference (MEATCON2019). 2019;333:UNSP 012030.
doi:10.1088/1755-1315/333/1/012030 .
Radulović, Stamen, Šefer, Dragan, Marković, Radmila, Lukić, M., Nikolić, Aleksandra, Milićević, Dragan, "Risk assessment and risk management of contaminants in the feed to food chain" in 60th International Meat Industry Conference (MEATCON2019), 333 (2019):UNSP 012030,
https://doi.org/10.1088/1755-1315/333/1/012030 . .

Mycotoxins as one of the foodborne risks most susceptible to climatic change

Nešić, Ksenija; Milićević, Dragan; Nešić, Vladimir; Ivanović, Snežana

(Elsevier Science Bv, Amsterdam, 2015)

TY  - CONF
AU  - Nešić, Ksenija
AU  - Milićević, Dragan
AU  - Nešić, Vladimir
AU  - Ivanović, Snežana
PY  - 2015
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/1265
AB  - The impact of climate change on agriculture and food safety is certain. This may affect mycotoxin concentrations as fungi with higher temperature optima for growth and mycotoxin production will dominate in regions with currently cooler climates, or become less prevalent as the temperatures become too high in areas where the temperature is already hot. In Serbia, recent drought and then flooding confirmed that mycotoxins are one of the foodborne hazards most susceptible to climate change. This paper ams to discuss the weather influence on the mycotoxicology situation and to point out the possibility of prediction and prevention of such future problems.
PB  - Elsevier Science Bv, Amsterdam
C3  - 58th International Meat Industry Conference (MEATCON2015)
T1  - Mycotoxins as one of the foodborne risks most susceptible to climatic change
VL  - 5
SP  - 207
EP  - 210
DO  - 10.1016/j.profoo.2015.09.058
ER  - 
@conference{
author = "Nešić, Ksenija and Milićević, Dragan and Nešić, Vladimir and Ivanović, Snežana",
year = "2015",
abstract = "The impact of climate change on agriculture and food safety is certain. This may affect mycotoxin concentrations as fungi with higher temperature optima for growth and mycotoxin production will dominate in regions with currently cooler climates, or become less prevalent as the temperatures become too high in areas where the temperature is already hot. In Serbia, recent drought and then flooding confirmed that mycotoxins are one of the foodborne hazards most susceptible to climate change. This paper ams to discuss the weather influence on the mycotoxicology situation and to point out the possibility of prediction and prevention of such future problems.",
publisher = "Elsevier Science Bv, Amsterdam",
journal = "58th International Meat Industry Conference (MEATCON2015)",
title = "Mycotoxins as one of the foodborne risks most susceptible to climatic change",
volume = "5",
pages = "207-210",
doi = "10.1016/j.profoo.2015.09.058"
}
Nešić, K., Milićević, D., Nešić, V.,& Ivanović, S.. (2015). Mycotoxins as one of the foodborne risks most susceptible to climatic change. in 58th International Meat Industry Conference (MEATCON2015)
Elsevier Science Bv, Amsterdam., 5, 207-210.
https://doi.org/10.1016/j.profoo.2015.09.058
Nešić K, Milićević D, Nešić V, Ivanović S. Mycotoxins as one of the foodborne risks most susceptible to climatic change. in 58th International Meat Industry Conference (MEATCON2015). 2015;5:207-210.
doi:10.1016/j.profoo.2015.09.058 .
Nešić, Ksenija, Milićević, Dragan, Nešić, Vladimir, Ivanović, Snežana, "Mycotoxins as one of the foodborne risks most susceptible to climatic change" in 58th International Meat Industry Conference (MEATCON2015), 5 (2015):207-210,
https://doi.org/10.1016/j.profoo.2015.09.058 . .
16
7

An outbreak of fumonisin toxicosis in horses in Serbia

Jovanović, M.; Trailović, Dragiša; Kukolj, Vladimir; Nešić, Slađan; Marinković, Darko; Nedeljković-Trailović, Jelena; Strajn, B. Jakovac; Milićević, Dragan

(Wageningen Academic Publishers, Wageningen, 2015)

TY  - JOUR
AU  - Jovanović, M.
AU  - Trailović, Dragiša
AU  - Kukolj, Vladimir
AU  - Nešić, Slađan
AU  - Marinković, Darko
AU  - Nedeljković-Trailović, Jelena
AU  - Strajn, B. Jakovac
AU  - Milićević, Dragan
PY  - 2015
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/1287
AB  - This paper reports on an outbreak of fumonisin toxicosis in a stable with 100 horses. Twenty-one horses were affected and fifteen died within a month. The animals were not febrile and exhibited poor appetite, somnolence, head pressing, blindness, ataxia, lethargy, and seizures, ending with death. The post mortem examination of the head of one 18-month-old colt revealed large, bilateral, slightly asymmetrical large areas of necrosis of the cerebral white matter. The lesions involved the frontal, parietal and occipital lobes only. Histological findings revealed leukomalacia with necrosis, infiltration of macrophages, neutrophils and eosinophils, haemorrhage and oedema of the surrounding grey matter. In response to the pathological findings, which indicated equine leukoencephalomalacia (ELEM), feed samples from the premises were tested for fumonisin B-1 and B-2 (FB1 and FB2). The milled maize samples contained 6.0 mg/kg FB1 and 2.4 mg/kg FB2, while the maize bran contained 6.05 mg/kg FB1 and 1.68 mg/kg FB2. These findings confirmed the diagnosis of fumonisin toxicosis. Hence, this report indicates that Serbia is one of the few regions in Europe with proven cases of ELEM.
PB  - Wageningen Academic Publishers, Wageningen
T2  - World Mycotoxin Journal
T1  - An outbreak of fumonisin toxicosis in horses in Serbia
VL  - 8
IS  - 4
SP  - 387
EP  - 391
DO  - 10.3920/WMJ2014.1812
ER  - 
@article{
author = "Jovanović, M. and Trailović, Dragiša and Kukolj, Vladimir and Nešić, Slađan and Marinković, Darko and Nedeljković-Trailović, Jelena and Strajn, B. Jakovac and Milićević, Dragan",
year = "2015",
abstract = "This paper reports on an outbreak of fumonisin toxicosis in a stable with 100 horses. Twenty-one horses were affected and fifteen died within a month. The animals were not febrile and exhibited poor appetite, somnolence, head pressing, blindness, ataxia, lethargy, and seizures, ending with death. The post mortem examination of the head of one 18-month-old colt revealed large, bilateral, slightly asymmetrical large areas of necrosis of the cerebral white matter. The lesions involved the frontal, parietal and occipital lobes only. Histological findings revealed leukomalacia with necrosis, infiltration of macrophages, neutrophils and eosinophils, haemorrhage and oedema of the surrounding grey matter. In response to the pathological findings, which indicated equine leukoencephalomalacia (ELEM), feed samples from the premises were tested for fumonisin B-1 and B-2 (FB1 and FB2). The milled maize samples contained 6.0 mg/kg FB1 and 2.4 mg/kg FB2, while the maize bran contained 6.05 mg/kg FB1 and 1.68 mg/kg FB2. These findings confirmed the diagnosis of fumonisin toxicosis. Hence, this report indicates that Serbia is one of the few regions in Europe with proven cases of ELEM.",
publisher = "Wageningen Academic Publishers, Wageningen",
journal = "World Mycotoxin Journal",
title = "An outbreak of fumonisin toxicosis in horses in Serbia",
volume = "8",
number = "4",
pages = "387-391",
doi = "10.3920/WMJ2014.1812"
}
Jovanović, M., Trailović, D., Kukolj, V., Nešić, S., Marinković, D., Nedeljković-Trailović, J., Strajn, B. J.,& Milićević, D.. (2015). An outbreak of fumonisin toxicosis in horses in Serbia. in World Mycotoxin Journal
Wageningen Academic Publishers, Wageningen., 8(4), 387-391.
https://doi.org/10.3920/WMJ2014.1812
Jovanović M, Trailović D, Kukolj V, Nešić S, Marinković D, Nedeljković-Trailović J, Strajn BJ, Milićević D. An outbreak of fumonisin toxicosis in horses in Serbia. in World Mycotoxin Journal. 2015;8(4):387-391.
doi:10.3920/WMJ2014.1812 .
Jovanović, M., Trailović, Dragiša, Kukolj, Vladimir, Nešić, Slađan, Marinković, Darko, Nedeljković-Trailović, Jelena, Strajn, B. Jakovac, Milićević, Dragan, "An outbreak of fumonisin toxicosis in horses in Serbia" in World Mycotoxin Journal, 8, no. 4 (2015):387-391,
https://doi.org/10.3920/WMJ2014.1812 . .
3
14
8
12

Comparative Investigation of the Efficacy of Three Different Adsorbents against OTA-Induced Toxicity in Broiler Chickens

Nedeljković-Trailović, Jelena; Trailović, Saša; Resanović, Radmila; Milićević, Dragan; Jovanović, Milijan; Vasiljević, Marko

(MDPI, Basel, 2015)

TY  - JOUR
AU  - Nedeljković-Trailović, Jelena
AU  - Trailović, Saša
AU  - Resanović, Radmila
AU  - Milićević, Dragan
AU  - Jovanović, Milijan
AU  - Vasiljević, Marko
PY  - 2015
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/1193
AB  - The aim of our study was to determine the efficacy of three different adsorbents, inorganic (modified zeolite), organic (esterified glucomannans) and mixed (inorganic and organic components, with the addition of enzymes), in protecting broilers from the toxic effects of ochratoxin A in feed. Broilers were fed diets containing 2 mg/kg of ochratoxin A (OTA) and supplemented with adsorbents at the recommended concentration of 2 g/kg for 21 days. The presence of OTA led to a notable reduction in body weight, lower weight gain, increased feed conversion and induced histopathological changes in the liver and kidneys. The presence of inorganic, organic and mixed adsorbents in contaminated feed only partially reduced the negative effects of OTA on the broiler performances. Broilers that were fed with adsorbent-supplemented feed reached higher body weight (17.96%, 19.09% and 13.59%), compared to the group that received only OTA. The presence of adsorbents partially alleviated the reduction in feed consumption (22.68%, 12.91% and 10.59%), and a similar effect was observed with feed conversion. The applied adsorbents have also reduced the intensity of histopathological changes caused by OTA; however, they were not able to prevent their onset. After the withdrawal of the toxin and adsorbents from the feed (21-42 days), all previously observed disturbances in broilers were reduced, but more remarkably in broilers fed with adsorbents.
PB  - MDPI, Basel
T2  - Toxins
T1  - Comparative Investigation of the Efficacy of Three Different Adsorbents against OTA-Induced Toxicity in Broiler Chickens
VL  - 7
IS  - 4
SP  - 1174
EP  - 1191
DO  - 10.3390/toxins7041174
ER  - 
@article{
author = "Nedeljković-Trailović, Jelena and Trailović, Saša and Resanović, Radmila and Milićević, Dragan and Jovanović, Milijan and Vasiljević, Marko",
year = "2015",
abstract = "The aim of our study was to determine the efficacy of three different adsorbents, inorganic (modified zeolite), organic (esterified glucomannans) and mixed (inorganic and organic components, with the addition of enzymes), in protecting broilers from the toxic effects of ochratoxin A in feed. Broilers were fed diets containing 2 mg/kg of ochratoxin A (OTA) and supplemented with adsorbents at the recommended concentration of 2 g/kg for 21 days. The presence of OTA led to a notable reduction in body weight, lower weight gain, increased feed conversion and induced histopathological changes in the liver and kidneys. The presence of inorganic, organic and mixed adsorbents in contaminated feed only partially reduced the negative effects of OTA on the broiler performances. Broilers that were fed with adsorbent-supplemented feed reached higher body weight (17.96%, 19.09% and 13.59%), compared to the group that received only OTA. The presence of adsorbents partially alleviated the reduction in feed consumption (22.68%, 12.91% and 10.59%), and a similar effect was observed with feed conversion. The applied adsorbents have also reduced the intensity of histopathological changes caused by OTA; however, they were not able to prevent their onset. After the withdrawal of the toxin and adsorbents from the feed (21-42 days), all previously observed disturbances in broilers were reduced, but more remarkably in broilers fed with adsorbents.",
publisher = "MDPI, Basel",
journal = "Toxins",
title = "Comparative Investigation of the Efficacy of Three Different Adsorbents against OTA-Induced Toxicity in Broiler Chickens",
volume = "7",
number = "4",
pages = "1174-1191",
doi = "10.3390/toxins7041174"
}
Nedeljković-Trailović, J., Trailović, S., Resanović, R., Milićević, D., Jovanović, M.,& Vasiljević, M.. (2015). Comparative Investigation of the Efficacy of Three Different Adsorbents against OTA-Induced Toxicity in Broiler Chickens. in Toxins
MDPI, Basel., 7(4), 1174-1191.
https://doi.org/10.3390/toxins7041174
Nedeljković-Trailović J, Trailović S, Resanović R, Milićević D, Jovanović M, Vasiljević M. Comparative Investigation of the Efficacy of Three Different Adsorbents against OTA-Induced Toxicity in Broiler Chickens. in Toxins. 2015;7(4):1174-1191.
doi:10.3390/toxins7041174 .
Nedeljković-Trailović, Jelena, Trailović, Saša, Resanović, Radmila, Milićević, Dragan, Jovanović, Milijan, Vasiljević, Marko, "Comparative Investigation of the Efficacy of Three Different Adsorbents against OTA-Induced Toxicity in Broiler Chickens" in Toxins, 7, no. 4 (2015):1174-1191,
https://doi.org/10.3390/toxins7041174 . .
15
13
21

Comparison of two analytical methods (ELISA and LC-MS/MS) for determination of aflatoxin B-1 in corn and aflatoxin M-1 in milk

Stefanović, Srđan; Spirić, Danka; Petronijević, Radivoj; Nedeljković-Trailović, Jelena; Milićević, Dragan; Nikolić, Dragica M.; Janković, Saša

(Elsevier Science Bv, Amsterdam, 2015)

TY  - CONF
AU  - Stefanović, Srđan
AU  - Spirić, Danka
AU  - Petronijević, Radivoj
AU  - Nedeljković-Trailović, Jelena
AU  - Milićević, Dragan
AU  - Nikolić, Dragica M.
AU  - Janković, Saša
PY  - 2015
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/1252
AB  - The aim of this paper is to assess the closeness of agreement between results of ELISA and LC-MS/MS methods for determination of aflatoxin B-1 in corn and aflatoxin M-1 in milk. Samples of corn (n=100) and milk (n=250) were simultaneously analyzed using ELISA and LC-MS/MS methods, after the severe drought that affected Serbia in summer 2012 resulting in occurrence of aflatoxin B1 in corn and aflatoxin M-1 in milk. Regression analysis showed higher level of agreement between aflatoxin B-1 samples (R2=0.994), compared to aflatoxin M-1 samples (r(2)=0.920). However, both techniques were satisfactory in meeting the requirements for official control purposes.
PB  - Elsevier Science Bv, Amsterdam
C3  - 58th International Meat Industry Conference (MEATCON2015)
T1  - Comparison of two analytical methods (ELISA and LC-MS/MS) for determination of aflatoxin B-1 in corn and aflatoxin M-1 in milk
VL  - 5
SP  - 270
EP  - 273
DO  - 10.1016/j.profoo.2015.09.077
ER  - 
@conference{
author = "Stefanović, Srđan and Spirić, Danka and Petronijević, Radivoj and Nedeljković-Trailović, Jelena and Milićević, Dragan and Nikolić, Dragica M. and Janković, Saša",
year = "2015",
abstract = "The aim of this paper is to assess the closeness of agreement between results of ELISA and LC-MS/MS methods for determination of aflatoxin B-1 in corn and aflatoxin M-1 in milk. Samples of corn (n=100) and milk (n=250) were simultaneously analyzed using ELISA and LC-MS/MS methods, after the severe drought that affected Serbia in summer 2012 resulting in occurrence of aflatoxin B1 in corn and aflatoxin M-1 in milk. Regression analysis showed higher level of agreement between aflatoxin B-1 samples (R2=0.994), compared to aflatoxin M-1 samples (r(2)=0.920). However, both techniques were satisfactory in meeting the requirements for official control purposes.",
publisher = "Elsevier Science Bv, Amsterdam",
journal = "58th International Meat Industry Conference (MEATCON2015)",
title = "Comparison of two analytical methods (ELISA and LC-MS/MS) for determination of aflatoxin B-1 in corn and aflatoxin M-1 in milk",
volume = "5",
pages = "270-273",
doi = "10.1016/j.profoo.2015.09.077"
}
Stefanović, S., Spirić, D., Petronijević, R., Nedeljković-Trailović, J., Milićević, D., Nikolić, D. M.,& Janković, S.. (2015). Comparison of two analytical methods (ELISA and LC-MS/MS) for determination of aflatoxin B-1 in corn and aflatoxin M-1 in milk. in 58th International Meat Industry Conference (MEATCON2015)
Elsevier Science Bv, Amsterdam., 5, 270-273.
https://doi.org/10.1016/j.profoo.2015.09.077
Stefanović S, Spirić D, Petronijević R, Nedeljković-Trailović J, Milićević D, Nikolić DM, Janković S. Comparison of two analytical methods (ELISA and LC-MS/MS) for determination of aflatoxin B-1 in corn and aflatoxin M-1 in milk. in 58th International Meat Industry Conference (MEATCON2015). 2015;5:270-273.
doi:10.1016/j.profoo.2015.09.077 .
Stefanović, Srđan, Spirić, Danka, Petronijević, Radivoj, Nedeljković-Trailović, Jelena, Milićević, Dragan, Nikolić, Dragica M., Janković, Saša, "Comparison of two analytical methods (ELISA and LC-MS/MS) for determination of aflatoxin B-1 in corn and aflatoxin M-1 in milk" in 58th International Meat Industry Conference (MEATCON2015), 5 (2015):270-273,
https://doi.org/10.1016/j.profoo.2015.09.077 . .
22
19

Occurrence of Listeria monocytogenes in a Serbian salmon and seafood processing line during 2013

Lakićević, Brankica; Baltić, Tatjana; Janković, Vesna; Velebit, Branko; Dimitrijević, Mirjana; Parunović, Nenad; Milićević, Dragan

(Elsevier Science Bv, Amsterdam, 2015)

TY  - CONF
AU  - Lakićević, Brankica
AU  - Baltić, Tatjana
AU  - Janković, Vesna
AU  - Velebit, Branko
AU  - Dimitrijević, Mirjana
AU  - Parunović, Nenad
AU  - Milićević, Dragan
PY  - 2015
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/1270
AB  - The objective of this study was to examine the occurrence of L. monocytogenes in a selected fish and seafood processing line. Results showed that during 2013, 12.4 %, 8.3 % and 2.3 % of fish, seafood salads and environmental swabs were positive for L. monocytogenes. All positive food samples showed a contamination level below 100 CFU/g. Environmental swabs from surface of slicing and trimming tables, slicing machines, fish filleting and trimming knives, belt glazer and working table were positive for L. monocytogenes. Therefore, strict attention must be paid to cleaning and disinfection to control the level of L. monocytogenes.
PB  - Elsevier Science Bv, Amsterdam
C3  - 58th International Meat Industry Conference (MEATCON2015)
T1  - Occurrence of Listeria monocytogenes in a Serbian salmon and seafood processing line during 2013
VL  - 5
SP  - 156
EP  - 159
DO  - 10.1016/j.profoo.2015.09.045
ER  - 
@conference{
author = "Lakićević, Brankica and Baltić, Tatjana and Janković, Vesna and Velebit, Branko and Dimitrijević, Mirjana and Parunović, Nenad and Milićević, Dragan",
year = "2015",
abstract = "The objective of this study was to examine the occurrence of L. monocytogenes in a selected fish and seafood processing line. Results showed that during 2013, 12.4 %, 8.3 % and 2.3 % of fish, seafood salads and environmental swabs were positive for L. monocytogenes. All positive food samples showed a contamination level below 100 CFU/g. Environmental swabs from surface of slicing and trimming tables, slicing machines, fish filleting and trimming knives, belt glazer and working table were positive for L. monocytogenes. Therefore, strict attention must be paid to cleaning and disinfection to control the level of L. monocytogenes.",
publisher = "Elsevier Science Bv, Amsterdam",
journal = "58th International Meat Industry Conference (MEATCON2015)",
title = "Occurrence of Listeria monocytogenes in a Serbian salmon and seafood processing line during 2013",
volume = "5",
pages = "156-159",
doi = "10.1016/j.profoo.2015.09.045"
}
Lakićević, B., Baltić, T., Janković, V., Velebit, B., Dimitrijević, M., Parunović, N.,& Milićević, D.. (2015). Occurrence of Listeria monocytogenes in a Serbian salmon and seafood processing line during 2013. in 58th International Meat Industry Conference (MEATCON2015)
Elsevier Science Bv, Amsterdam., 5, 156-159.
https://doi.org/10.1016/j.profoo.2015.09.045
Lakićević B, Baltić T, Janković V, Velebit B, Dimitrijević M, Parunović N, Milićević D. Occurrence of Listeria monocytogenes in a Serbian salmon and seafood processing line during 2013. in 58th International Meat Industry Conference (MEATCON2015). 2015;5:156-159.
doi:10.1016/j.profoo.2015.09.045 .
Lakićević, Brankica, Baltić, Tatjana, Janković, Vesna, Velebit, Branko, Dimitrijević, Mirjana, Parunović, Nenad, Milićević, Dragan, "Occurrence of Listeria monocytogenes in a Serbian salmon and seafood processing line during 2013" in 58th International Meat Industry Conference (MEATCON2015), 5 (2015):156-159,
https://doi.org/10.1016/j.profoo.2015.09.045 . .

The role of total fats, saturated/unsaturated fatty acids and cholesterol content in chicken meat as cardiovascular risk factors

Milićević, Dragan; Vranić, Danijela; Masić, Zoran; Parunović, Nenad; Trbović, Dejana; Nedeljković-Trailović, Jelena; Petrović, Zoran

(BMC, London, 2014)

TY  - JOUR
AU  - Milićević, Dragan
AU  - Vranić, Danijela
AU  - Masić, Zoran
AU  - Parunović, Nenad
AU  - Trbović, Dejana
AU  - Nedeljković-Trailović, Jelena
AU  - Petrović, Zoran
PY  - 2014
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/1106
AB  - Background: The objective of the study was to present information about the chemical composition, the fatty acids profile, and cholesterol content of chicken meat in order to investigate the impact of chicken meat consumption on cardiovascular risk in the general population. Methods: A total of 48 6-wk-old broiler chickens broilers from two farms in June to November of 2012, and February of 2013, were used in this trial. Total lipid content was determined by extraction of fat by petrol ether (Soxhlet) after acid hydrolysis of samples. Fatty acids were determined by capillary gas chromatography. Cholesterol determination was performed by using HPLC/PDA system. Results: The results indicate that the total free cholesterol content in raw breast and drumstick of chickens was in the range of 37,41-79,9 mg/100 g and 48,35-99,5 mg/100 g, respectively. The main fatty acids identified in all cuts were C18:1c9, C18:2n6, C16:0, C18:0, and C16:1. Decreasing the dietary n-6/n-3 clearly decreased the content in breast and drumstick muscle of C18:2n6, C18:3n3, and C20:3n6, but increased that of C16:0, C18:0, and C20:2. Also, the major saturated fatty acid (SFA) (C16:0 and C18:0) was significantly differ among the four treatments. Conclusion: Our study shows that dietary fat and fatty acid composition influence the concentrations of total cholesterol content, total fat content, and fatty acid composition in broiler muscle. This information will aid in determining the burden of chicken meat as a cardiovascular risk factors disease and act as a planning tool for public-health Programmes.
PB  - BMC, London
T2  - Lipids in Health and Disease
T1  - The role of total fats, saturated/unsaturated fatty acids and cholesterol content in chicken meat as cardiovascular risk factors
VL  - 13
SP  - 42
DO  - 10.1186/1476-511X-13-42
ER  - 
@article{
author = "Milićević, Dragan and Vranić, Danijela and Masić, Zoran and Parunović, Nenad and Trbović, Dejana and Nedeljković-Trailović, Jelena and Petrović, Zoran",
year = "2014",
abstract = "Background: The objective of the study was to present information about the chemical composition, the fatty acids profile, and cholesterol content of chicken meat in order to investigate the impact of chicken meat consumption on cardiovascular risk in the general population. Methods: A total of 48 6-wk-old broiler chickens broilers from two farms in June to November of 2012, and February of 2013, were used in this trial. Total lipid content was determined by extraction of fat by petrol ether (Soxhlet) after acid hydrolysis of samples. Fatty acids were determined by capillary gas chromatography. Cholesterol determination was performed by using HPLC/PDA system. Results: The results indicate that the total free cholesterol content in raw breast and drumstick of chickens was in the range of 37,41-79,9 mg/100 g and 48,35-99,5 mg/100 g, respectively. The main fatty acids identified in all cuts were C18:1c9, C18:2n6, C16:0, C18:0, and C16:1. Decreasing the dietary n-6/n-3 clearly decreased the content in breast and drumstick muscle of C18:2n6, C18:3n3, and C20:3n6, but increased that of C16:0, C18:0, and C20:2. Also, the major saturated fatty acid (SFA) (C16:0 and C18:0) was significantly differ among the four treatments. Conclusion: Our study shows that dietary fat and fatty acid composition influence the concentrations of total cholesterol content, total fat content, and fatty acid composition in broiler muscle. This information will aid in determining the burden of chicken meat as a cardiovascular risk factors disease and act as a planning tool for public-health Programmes.",
publisher = "BMC, London",
journal = "Lipids in Health and Disease",
title = "The role of total fats, saturated/unsaturated fatty acids and cholesterol content in chicken meat as cardiovascular risk factors",
volume = "13",
pages = "42",
doi = "10.1186/1476-511X-13-42"
}
Milićević, D., Vranić, D., Masić, Z., Parunović, N., Trbović, D., Nedeljković-Trailović, J.,& Petrović, Z.. (2014). The role of total fats, saturated/unsaturated fatty acids and cholesterol content in chicken meat as cardiovascular risk factors. in Lipids in Health and Disease
BMC, London., 13, 42.
https://doi.org/10.1186/1476-511X-13-42
Milićević D, Vranić D, Masić Z, Parunović N, Trbović D, Nedeljković-Trailović J, Petrović Z. The role of total fats, saturated/unsaturated fatty acids and cholesterol content in chicken meat as cardiovascular risk factors. in Lipids in Health and Disease. 2014;13:42.
doi:10.1186/1476-511X-13-42 .
Milićević, Dragan, Vranić, Danijela, Masić, Zoran, Parunović, Nenad, Trbović, Dejana, Nedeljković-Trailović, Jelena, Petrović, Zoran, "The role of total fats, saturated/unsaturated fatty acids and cholesterol content in chicken meat as cardiovascular risk factors" in Lipids in Health and Disease, 13 (2014):42,
https://doi.org/10.1186/1476-511X-13-42 . .
4
77
39
76

Cadmium and mercury accumulation in European hare (Lepus europaeus): age-dependent relationships in renal and hepatic tissue

Petrović, Zoran; Teodorović, Vlado; Đurić, Spomenka; Milićević, Dragan; Vranić, Danijela; Lukić, Mirjana

(Springer Heidelberg, Heidelberg, 2014)

TY  - JOUR
AU  - Petrović, Zoran
AU  - Teodorović, Vlado
AU  - Đurić, Spomenka
AU  - Milićević, Dragan
AU  - Vranić, Danijela
AU  - Lukić, Mirjana
PY  - 2014
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/1100
AB  - A total of 63 European hares have been collected from five Serbian agricultural regions. The hares assayed were divided into four age groups (3-6 months, 12 months, 12-24 months, and 24-36 months) and investigated upon presence at cadmium (Cd) and mercury (Hg) in the kidney and liver. The positive significant correlation (Ps-Pearsons coefficient) between Cd concentrations in the kidney and liver within age group the 3-6 months was found (Ps = 0.81, p < 0.001). Differences between Cd content in the kidney in comparison to liver were significant within all presented age groups (p < 0.001). Differences between recorded Hg levels in the kidney were not significant between presented age groups (p > 0.05). Statistically significant differences were registered between Hg content in the liver of the hares aged 24-36 and 12 months (p < 0.05). There were no statistically significant correlations registered between Hg concentrations in the kidney and liver within any particular age group (p > 0.05). The strong statistically significant associations were registered between Cd and Hg content in the liver (Cd L/Hg L) in the age group 3-6 and 12-24 months (Cd L/Hg L, Ps = 0.94; p < 0.001 and Ps = 0.91; p < 0.001, respectively). The polynomial regression model used for graphing the observed data seems to be a method for modeling the relationship between measured Cd and Hg concentrations in the liver and kidney as first approximation for bioaccumulation in hares.
PB  - Springer Heidelberg, Heidelberg
T2  - Environmental Science and Pollution Research
T1  - Cadmium and mercury accumulation in European hare (Lepus europaeus): age-dependent relationships in renal and hepatic tissue
VL  - 21
IS  - 24
SP  - 14058
EP  - 14068
DO  - 10.1007/s11356-014-3290-0
ER  - 
@article{
author = "Petrović, Zoran and Teodorović, Vlado and Đurić, Spomenka and Milićević, Dragan and Vranić, Danijela and Lukić, Mirjana",
year = "2014",
abstract = "A total of 63 European hares have been collected from five Serbian agricultural regions. The hares assayed were divided into four age groups (3-6 months, 12 months, 12-24 months, and 24-36 months) and investigated upon presence at cadmium (Cd) and mercury (Hg) in the kidney and liver. The positive significant correlation (Ps-Pearsons coefficient) between Cd concentrations in the kidney and liver within age group the 3-6 months was found (Ps = 0.81, p < 0.001). Differences between Cd content in the kidney in comparison to liver were significant within all presented age groups (p < 0.001). Differences between recorded Hg levels in the kidney were not significant between presented age groups (p > 0.05). Statistically significant differences were registered between Hg content in the liver of the hares aged 24-36 and 12 months (p < 0.05). There were no statistically significant correlations registered between Hg concentrations in the kidney and liver within any particular age group (p > 0.05). The strong statistically significant associations were registered between Cd and Hg content in the liver (Cd L/Hg L) in the age group 3-6 and 12-24 months (Cd L/Hg L, Ps = 0.94; p < 0.001 and Ps = 0.91; p < 0.001, respectively). The polynomial regression model used for graphing the observed data seems to be a method for modeling the relationship between measured Cd and Hg concentrations in the liver and kidney as first approximation for bioaccumulation in hares.",
publisher = "Springer Heidelberg, Heidelberg",
journal = "Environmental Science and Pollution Research",
title = "Cadmium and mercury accumulation in European hare (Lepus europaeus): age-dependent relationships in renal and hepatic tissue",
volume = "21",
number = "24",
pages = "14058-14068",
doi = "10.1007/s11356-014-3290-0"
}
Petrović, Z., Teodorović, V., Đurić, S., Milićević, D., Vranić, D.,& Lukić, M.. (2014). Cadmium and mercury accumulation in European hare (Lepus europaeus): age-dependent relationships in renal and hepatic tissue. in Environmental Science and Pollution Research
Springer Heidelberg, Heidelberg., 21(24), 14058-14068.
https://doi.org/10.1007/s11356-014-3290-0
Petrović Z, Teodorović V, Đurić S, Milićević D, Vranić D, Lukić M. Cadmium and mercury accumulation in European hare (Lepus europaeus): age-dependent relationships in renal and hepatic tissue. in Environmental Science and Pollution Research. 2014;21(24):14058-14068.
doi:10.1007/s11356-014-3290-0 .
Petrović, Zoran, Teodorović, Vlado, Đurić, Spomenka, Milićević, Dragan, Vranić, Danijela, Lukić, Mirjana, "Cadmium and mercury accumulation in European hare (Lepus europaeus): age-dependent relationships in renal and hepatic tissue" in Environmental Science and Pollution Research, 21, no. 24 (2014):14058-14068,
https://doi.org/10.1007/s11356-014-3290-0 . .
11
4
8

Environmental Cd and Zn Concentrations in Liver and Kidney of European Hare from Different Serbian Regions: Age and Tissue Differences

Petrović, Zoran; Teodorović, Vlado; Dimitrijević, Mirjana; Borozan, Sunčica; Beuković, Milos; Milićević, Dragan

(Springer, New York, 2013)

TY  - JOUR
AU  - Petrović, Zoran
AU  - Teodorović, Vlado
AU  - Dimitrijević, Mirjana
AU  - Borozan, Sunčica
AU  - Beuković, Milos
AU  - Milićević, Dragan
PY  - 2013
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/1042
AB  - A total of 84 European hares collected from eleven Serbian regions investigated upon cadmium (Cd) and zinc (Zn) presence. Strong statistically significant correlations between Cd concentrations in kidney and liver were registered in animals older than 12 months. Significant differences between Zn concentrations in liver in comparison to kidney were found within every single age group with exception of the oldest. Negative correlation (Ps-Pearsons correlation) between Zn and Cd concentrations were found in liver samples within the age group of 12 months (Ps = -0.67, p = 0.004).
PB  - Springer, New York
T2  - Bulletin of Environmental Contamination and Toxicology
T1  - Environmental Cd and Zn Concentrations in Liver and Kidney of European Hare from Different Serbian Regions: Age and Tissue Differences
VL  - 90
IS  - 2
SP  - 203
EP  - 207
DO  - 10.1007/s00128-012-0901-7
ER  - 
@article{
author = "Petrović, Zoran and Teodorović, Vlado and Dimitrijević, Mirjana and Borozan, Sunčica and Beuković, Milos and Milićević, Dragan",
year = "2013",
abstract = "A total of 84 European hares collected from eleven Serbian regions investigated upon cadmium (Cd) and zinc (Zn) presence. Strong statistically significant correlations between Cd concentrations in kidney and liver were registered in animals older than 12 months. Significant differences between Zn concentrations in liver in comparison to kidney were found within every single age group with exception of the oldest. Negative correlation (Ps-Pearsons correlation) between Zn and Cd concentrations were found in liver samples within the age group of 12 months (Ps = -0.67, p = 0.004).",
publisher = "Springer, New York",
journal = "Bulletin of Environmental Contamination and Toxicology",
title = "Environmental Cd and Zn Concentrations in Liver and Kidney of European Hare from Different Serbian Regions: Age and Tissue Differences",
volume = "90",
number = "2",
pages = "203-207",
doi = "10.1007/s00128-012-0901-7"
}
Petrović, Z., Teodorović, V., Dimitrijević, M., Borozan, S., Beuković, M.,& Milićević, D.. (2013). Environmental Cd and Zn Concentrations in Liver and Kidney of European Hare from Different Serbian Regions: Age and Tissue Differences. in Bulletin of Environmental Contamination and Toxicology
Springer, New York., 90(2), 203-207.
https://doi.org/10.1007/s00128-012-0901-7
Petrović Z, Teodorović V, Dimitrijević M, Borozan S, Beuković M, Milićević D. Environmental Cd and Zn Concentrations in Liver and Kidney of European Hare from Different Serbian Regions: Age and Tissue Differences. in Bulletin of Environmental Contamination and Toxicology. 2013;90(2):203-207.
doi:10.1007/s00128-012-0901-7 .
Petrović, Zoran, Teodorović, Vlado, Dimitrijević, Mirjana, Borozan, Sunčica, Beuković, Milos, Milićević, Dragan, "Environmental Cd and Zn Concentrations in Liver and Kidney of European Hare from Different Serbian Regions: Age and Tissue Differences" in Bulletin of Environmental Contamination and Toxicology, 90, no. 2 (2013):203-207,
https://doi.org/10.1007/s00128-012-0901-7 . .
26
18
25

Presence of ochratoxin A and toxic elements residue in tissues and their impact on safety of pork

Milićević, Dragan; Jovanović, Milijan; Jurić, Verica; Daković, Aleksandra; Stefanović, Srđan; Petrović, Zoran

(Fakultet veterinarske medicine, Beograd, Srbija, 2008)

TY  - JOUR
AU  - Milićević, Dragan
AU  - Jovanović, Milijan
AU  - Jurić, Verica
AU  - Daković, Aleksandra
AU  - Stefanović, Srđan
AU  - Petrović, Zoran
PY  - 2008
UR  - https://doaj.org/article/d9e4b2510b3343efa42f6b3b837f7f90
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/1952
AB  - The aim and task of this study was to determine the presence of ochratoxin A (OTA) in blood serum, liver and kidneys of fattening swine, slaughtered regularly, originating from different areas of Serbia. During meat inspection on the slaughterhouse line samples of blood, kidney and liver per animal were randomly sampled (n=90) and analyzed by HPLC for ochratoxin A. Also, the presence of nephrotoxic (cadmium, lead, mercury and arsenic) elements in kidneys was carried out. Of the 90 liver samples, 26.6% contained OTA in the range of 0.22-14.5 ng/g, while the incidence of OTA in serum and kidney samples were very similar (31 and 33.3%, respectively). The analyses showed that serum samples were positive in the range of 0.22-221 ng/mL, while ochratoxin A concentrations in the kidney were between 0.17 and 52.5 ng/g. The mean distribution of OTA residue followed the pattern: serum>kidneys>liver (100>34>17), while in respect to occurrence it followed the pattern: kidneys>serum>liver (100>93.4>79.9). The results of this study showed that 2.2% of kidney sample had a content of ochratoxin A above the maximum permitted limit in Serbia of 10 ng/g. The results from this survey indicated that there was a low correlation between the OTA level in serum and liver as well as in the OTA level in kidney and liver (r=0.319 and 0.341, respectively) while the strongest correlation was found between the OTA level in serum and in kidney (r=0.973). The presence of mercury was found in 33.3% of kidney samples in the range of 0.005-0.055 mg/kg, while the presence of cadmium was found to a lesser degree (27.7%). The Hg concentrations in the kidney samples were lower than 0.10 mg/kg and did not exceed the guideline level established in Serbia, while concentration of cadmium in only one kidney sample was greater than 1.0 mg/kg, and exceeded the limit proposed by the Serbian Rule Book. The presence of arsenic was found only in one sample, while the presence of lead was not established. This study shows the presence of OTA in Serbian slaughtered pigs at levels comparable to those reported in other countries.
AB  - Cilj ovog rada je bio da se utvrdi prisustvo rezidua ohratoksina A (OTA) i toksičnih elemenata (kadmijum, olovo, živa i arsen) u tkivima zaklanih, tovnih svinja, poreklom iz različitih regiona Srbije. Tokom veterinarsko-sanitarnog pregleda zaklanih svinja, na liniji klanja, metodom slučajnog uzorkovanja uzimani su uzorci krvi, a zatim pripadajuća jetra i bubrezi, odgovarajuće životinje (n=90). Prisustvo rezidua OTA utvrđeno je u 26,6% uzoraka jetre u količini od 0,22 do 14,5 ng/g, dok je zastupljenost rezidua OTA u uzorcima krvne plazme i bubrega bila skoro identična (31,1 i 33,3%, ponaosob). Sadržaj OTA u uzorcima krvne plazme kretao se od 0,22 do 220,8 ng/mL, dok se u uzorcima bubrega kretao od 0,17 do 52,5 ng/g. Distribucija OTA u ispitanim tkivima (u %) u odnosu na sadržaj kretala se sledećim redosledom: krvna plazma> bubrezi>jetra (100>34>17), dok se u odnosu na zastupljenost rezidua kretala sledećim redosledom bubrezi>krvna plazma>jetra (100> 93,4>79,9). Rezultati naših istraživanja ukazuju na to da je u 2,2% ispitanih uzoraka bubrega utvrđen sadržaj OTA iznad maksimalno dozvoljene granice (10 ng/g). Nizak stepen pozitivne korelacije utvrđen je između sadržaja OTA u krvnoj plazmi i jetri (r=0,319), kao i između sadržaja OTA u jetri i bubrezima (r=0,341). Vrlo visok stepen pozitivne korelacije utvrđen je između sadržaja OTA u krvnoj plazmi i bubrezima (r=0,973). Prisustvo rezidua žive utvrđeno je u 33,3% uzoraka bubrega, u odnosu na učestalost nalaza rezidua kadmijuma koja je bila nešto manja (27,7%). Sadržaj žive kretao se u granicama predviđenim pravilnikom (0,005-0,055 mg/kg), dok je sadržaj kadmijuma u jednom uzorku bio iznad maksimalno dozvoljene granice (1,23 mg/kg). Prisustvo arsena utvrđeno je samo u jednom uzorku, dok prisustvo olova nije utvrđeno.
PB  - Fakultet veterinarske medicine, Beograd, Srbija
T2  - Veterinarski Glasnik
T1  - Presence of ochratoxin A and toxic elements residue in tissues and their impact on safety of pork
T1  - Uticaj prisustva rezidua ohratoksina a i toksičnih elemenata u tkivima na bezbednost svinjskog mesa
VL  - 62
IS  - 5-6
SP  - 359
EP  - 371
DO  - 10.2298/VETGL0806359M
ER  - 
@article{
author = "Milićević, Dragan and Jovanović, Milijan and Jurić, Verica and Daković, Aleksandra and Stefanović, Srđan and Petrović, Zoran",
year = "2008",
abstract = "The aim and task of this study was to determine the presence of ochratoxin A (OTA) in blood serum, liver and kidneys of fattening swine, slaughtered regularly, originating from different areas of Serbia. During meat inspection on the slaughterhouse line samples of blood, kidney and liver per animal were randomly sampled (n=90) and analyzed by HPLC for ochratoxin A. Also, the presence of nephrotoxic (cadmium, lead, mercury and arsenic) elements in kidneys was carried out. Of the 90 liver samples, 26.6% contained OTA in the range of 0.22-14.5 ng/g, while the incidence of OTA in serum and kidney samples were very similar (31 and 33.3%, respectively). The analyses showed that serum samples were positive in the range of 0.22-221 ng/mL, while ochratoxin A concentrations in the kidney were between 0.17 and 52.5 ng/g. The mean distribution of OTA residue followed the pattern: serum>kidneys>liver (100>34>17), while in respect to occurrence it followed the pattern: kidneys>serum>liver (100>93.4>79.9). The results of this study showed that 2.2% of kidney sample had a content of ochratoxin A above the maximum permitted limit in Serbia of 10 ng/g. The results from this survey indicated that there was a low correlation between the OTA level in serum and liver as well as in the OTA level in kidney and liver (r=0.319 and 0.341, respectively) while the strongest correlation was found between the OTA level in serum and in kidney (r=0.973). The presence of mercury was found in 33.3% of kidney samples in the range of 0.005-0.055 mg/kg, while the presence of cadmium was found to a lesser degree (27.7%). The Hg concentrations in the kidney samples were lower than 0.10 mg/kg and did not exceed the guideline level established in Serbia, while concentration of cadmium in only one kidney sample was greater than 1.0 mg/kg, and exceeded the limit proposed by the Serbian Rule Book. The presence of arsenic was found only in one sample, while the presence of lead was not established. This study shows the presence of OTA in Serbian slaughtered pigs at levels comparable to those reported in other countries., Cilj ovog rada je bio da se utvrdi prisustvo rezidua ohratoksina A (OTA) i toksičnih elemenata (kadmijum, olovo, živa i arsen) u tkivima zaklanih, tovnih svinja, poreklom iz različitih regiona Srbije. Tokom veterinarsko-sanitarnog pregleda zaklanih svinja, na liniji klanja, metodom slučajnog uzorkovanja uzimani su uzorci krvi, a zatim pripadajuća jetra i bubrezi, odgovarajuće životinje (n=90). Prisustvo rezidua OTA utvrđeno je u 26,6% uzoraka jetre u količini od 0,22 do 14,5 ng/g, dok je zastupljenost rezidua OTA u uzorcima krvne plazme i bubrega bila skoro identična (31,1 i 33,3%, ponaosob). Sadržaj OTA u uzorcima krvne plazme kretao se od 0,22 do 220,8 ng/mL, dok se u uzorcima bubrega kretao od 0,17 do 52,5 ng/g. Distribucija OTA u ispitanim tkivima (u %) u odnosu na sadržaj kretala se sledećim redosledom: krvna plazma> bubrezi>jetra (100>34>17), dok se u odnosu na zastupljenost rezidua kretala sledećim redosledom bubrezi>krvna plazma>jetra (100> 93,4>79,9). Rezultati naših istraživanja ukazuju na to da je u 2,2% ispitanih uzoraka bubrega utvrđen sadržaj OTA iznad maksimalno dozvoljene granice (10 ng/g). Nizak stepen pozitivne korelacije utvrđen je između sadržaja OTA u krvnoj plazmi i jetri (r=0,319), kao i između sadržaja OTA u jetri i bubrezima (r=0,341). Vrlo visok stepen pozitivne korelacije utvrđen je između sadržaja OTA u krvnoj plazmi i bubrezima (r=0,973). Prisustvo rezidua žive utvrđeno je u 33,3% uzoraka bubrega, u odnosu na učestalost nalaza rezidua kadmijuma koja je bila nešto manja (27,7%). Sadržaj žive kretao se u granicama predviđenim pravilnikom (0,005-0,055 mg/kg), dok je sadržaj kadmijuma u jednom uzorku bio iznad maksimalno dozvoljene granice (1,23 mg/kg). Prisustvo arsena utvrđeno je samo u jednom uzorku, dok prisustvo olova nije utvrđeno.",
publisher = "Fakultet veterinarske medicine, Beograd, Srbija",
journal = "Veterinarski Glasnik",
title = "Presence of ochratoxin A and toxic elements residue in tissues and their impact on safety of pork, Uticaj prisustva rezidua ohratoksina a i toksičnih elemenata u tkivima na bezbednost svinjskog mesa",
volume = "62",
number = "5-6",
pages = "359-371",
doi = "10.2298/VETGL0806359M"
}
Milićević, D., Jovanović, M., Jurić, V., Daković, A., Stefanović, S.,& Petrović, Z.. (2008). Presence of ochratoxin A and toxic elements residue in tissues and their impact on safety of pork. in Veterinarski Glasnik
Fakultet veterinarske medicine, Beograd, Srbija., 62(5-6), 359-371.
https://doi.org/10.2298/VETGL0806359M
Milićević D, Jovanović M, Jurić V, Daković A, Stefanović S, Petrović Z. Presence of ochratoxin A and toxic elements residue in tissues and their impact on safety of pork. in Veterinarski Glasnik. 2008;62(5-6):359-371.
doi:10.2298/VETGL0806359M .
Milićević, Dragan, Jovanović, Milijan, Jurić, Verica, Daković, Aleksandra, Stefanović, Srđan, Petrović, Zoran, "Presence of ochratoxin A and toxic elements residue in tissues and their impact on safety of pork" in Veterinarski Glasnik, 62, no. 5-6 (2008):359-371,
https://doi.org/10.2298/VETGL0806359M . .