TY  - CONF
AU  - Plut, Jan
AU  - Spariosu, Kristina
AU  - Radaković, Milena
AU  - Francuski Andrić, Jelena
AU  - Nemec Svete, Alenka
AU  - Jamnikar Ciglenečki, Urška
AU  - Štukelj, Marina
AU  - Kovačević Filipović, Milica
PY  - 2024
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/3910
AB  - Анализа биомаркера оралне течности представља иновативан приступ провери здравственог статуса животиња. Лучење пљувачне амилазе (amylase, AMY), холинестеразе (cholinesterase, CHE), хаптоглобина (haptoglobin, HPT), аденозин деаминазе (adenosine deaminase, ADA) и матрикс-металопротеиназа (matrix metalloproteinase, MMP) је повећано током стреса, инфламације, имунског одговора, и оштећења пљувачне жлезде. Такође, показано је да је орална течност добар материјал за детекцију вируса репродуктивног и респираторног синдрома свиња (porcine reproductive and respiratory syndrome virus, PRRSV). Циљ ове експерименталне студије је био да се испита да ли су маркери стреса, инфламације, имунитета и оштећења ткива измењени код назимица инфицираних PRRSV-ом. У студију су укључене две групе назимица (2 × n=16), сукцесивно инфициране и PRRSV-пљувачка позитивне, и једна здрава група назимица (n=16), хибрида ландраса и велике беле свиње. Почев од нултог дана (Т0), током наредне четири недеље, узорци оралне течности су прикупљени помоћу памучних конопаца, остављених слободно у обору, током сат и по времена. Концентрације протеина и НРТ-а су одређене спектрофотометријски. Ниво AMY-е, CHE-е и ADA-е, одређен је комерцијалним тестовима. Активност желатинолитичких ММР је процењена електрофорезом на гелу полиакриламида (sodium dodecyl sulfate-polyacrylamide gel electrophoresis, SDS-PAGE). За сваку анализу и групу, резултати су саопштени по тачкама узорковања (Т0-Т4). Хаптоглобин је детектован само у узорцима инфицираних свиња, док је код контрола био немерљив. Инфициране назимице су имале ниже вредности параметара стреса (AMY, CHE) и имунитета (ADA), у поређењу са контролама. Желатинолитичка електрофореза је показала сигнале ММР-2 и -9 код инфицираних, и зимогену и активну форму ММР-9 код контрола. Хаптоглобин и ММР-2 и -9 у обе инфициране групе одраз су локалног инфламаторног одговора пљувачне жлезде. Нижа активност AMY-е и CHE-е у узорцима PRRSV назимица може указати на измењену функцију пљувачне жлезде, која је довела до неочекиваног пада маркера стреса, док нижи ниво ADA-е може бити последица супресије имунског одговора. Аналазирани параметри могу бити значајни за проверу одговора свиња на инфекцију.
AB  - An innovative approach to assess health status in animals is by analyzing oral fluid biomarkers. Salivary secretion of amylase (AMY), cholinesterase (CHE), haptoglobin (HPT), adenosine deaminase (ADA), and matrix metalloproteinases (MMPs) is altered in stress, inflammation, immune response, and salivary gland injury. Moreover, it was shown that oral fluid is an effective matrix for detection of porcine reproductive and respiratory syndrome virus (PRRSV). This experimental study aimed to investigate if salivary biomarkers of stress, inflammation, immunity and tissue injury are changed in gilts with PRRSV. Two groups, subsequently infected and PRRSV-saliva positive, and one healthy group were included, each consisting of 16 replacement gilts, hybrids of Landrace Large White. Starting from day zero (T0), during the next four weeks, oral fluid samples were collected using cotton ropes, disposed for half-an-hour in the pens. Total protein and HPT concentrations were determined by spectrophotometry. Levels of AMY, CHE, and ADA were evaluated using commercial tests. Gelatinolytic activity of MMPs was estimated by sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE). For each analyte and group, results were given at all sampling points (T0-T4). The infected groups had detectable while the control had undetectable HPT levels. The infected gilts had lower activity of stress (AMY, CHE) and immunity (ADA) biomarkers, compared to the controls. Gelatinolytic analysis revealed MMP-2 and -9 signals in the PRRSV groups, and zymogen and active MMP-9 in the controls. Haptoglobin and MMP-2 and -9 in both of the infected groups contribute to the local salivary gland inflammatory response. Lower AMY and CHE activity in the oral fluid of PRRSV gilts could indicate altered salivary gland function that led to an unexpected drop in the stress markers, while lower ADA levels can be attributed to the suppressed immune response. All analyzed parameters could be valuable in testing porcine reaction to infection.
PB  - Beograd : Srpsko veterinarsko društvo, Sekcija za zoonoze
C3  - XXVI Simpozijum epizootiologa i epidemiologa (XXVI Epizootiološki dani), Banja Koviljača, 10 - 12. april 2024
T1  - Biomarkeri stresa, inflamacije i imuniteta u oralnoj tečnosti nazimica sa reproduktivnim i respiratornim sindromom
T1  - Stress, inflammation and immunity oral fluid biomarkers in gilts with porcine reproductive and respiratory syndrome
SP  - 104
EP  - 105
UR  - https://hdl.handle.net/21.15107/rcub_veterinar_3910
ER  - 

@conference{
author = "Plut, Jan and Spariosu, Kristina and Radaković, Milena and Francuski Andrić, Jelena and Nemec Svete, Alenka and Jamnikar Ciglenečki, Urška and Štukelj, Marina and Kovačević Filipović, Milica",
year = "2024",
abstract = "Анализа биомаркера оралне течности представља иновативан приступ провери здравственог статуса животиња. Лучење пљувачне амилазе (amylase, AMY), холинестеразе (cholinesterase, CHE), хаптоглобина (haptoglobin, HPT), аденозин деаминазе (adenosine deaminase, ADA) и матрикс-металопротеиназа (matrix metalloproteinase, MMP) је повећано током стреса, инфламације, имунског одговора, и оштећења пљувачне жлезде. Такође, показано је да је орална течност добар материјал за детекцију вируса репродуктивног и респираторног синдрома свиња (porcine reproductive and respiratory syndrome virus, PRRSV). Циљ ове експерименталне студије је био да се испита да ли су маркери стреса, инфламације, имунитета и оштећења ткива измењени код назимица инфицираних PRRSV-ом. У студију су укључене две групе назимица (2 × n=16), сукцесивно инфициране и PRRSV-пљувачка позитивне, и једна здрава група назимица (n=16), хибрида ландраса и велике беле свиње. Почев од нултог дана (Т0), током наредне четири недеље, узорци оралне течности су прикупљени помоћу памучних конопаца, остављених слободно у обору, током сат и по времена. Концентрације протеина и НРТ-а су одређене спектрофотометријски. Ниво AMY-е, CHE-е и ADA-е, одређен је комерцијалним тестовима. Активност желатинолитичких ММР је процењена електрофорезом на гелу полиакриламида (sodium dodecyl sulfate-polyacrylamide gel electrophoresis, SDS-PAGE). За сваку анализу и групу, резултати су саопштени по тачкама узорковања (Т0-Т4). Хаптоглобин је детектован само у узорцима инфицираних свиња, док је код контрола био немерљив. Инфициране назимице су имале ниже вредности параметара стреса (AMY, CHE) и имунитета (ADA), у поређењу са контролама. Желатинолитичка електрофореза је показала сигнале ММР-2 и -9 код инфицираних, и зимогену и активну форму ММР-9 код контрола. Хаптоглобин и ММР-2 и -9 у обе инфициране групе одраз су локалног инфламаторног одговора пљувачне жлезде. Нижа активност AMY-е и CHE-е у узорцима PRRSV назимица може указати на измењену функцију пљувачне жлезде, која је довела до неочекиваног пада маркера стреса, док нижи ниво ADA-е може бити последица супресије имунског одговора. Аналазирани параметри могу бити значајни за проверу одговора свиња на инфекцију., An innovative approach to assess health status in animals is by analyzing oral fluid biomarkers. Salivary secretion of amylase (AMY), cholinesterase (CHE), haptoglobin (HPT), adenosine deaminase (ADA), and matrix metalloproteinases (MMPs) is altered in stress, inflammation, immune response, and salivary gland injury. Moreover, it was shown that oral fluid is an effective matrix for detection of porcine reproductive and respiratory syndrome virus (PRRSV). This experimental study aimed to investigate if salivary biomarkers of stress, inflammation, immunity and tissue injury are changed in gilts with PRRSV. Two groups, subsequently infected and PRRSV-saliva positive, and one healthy group were included, each consisting of 16 replacement gilts, hybrids of Landrace Large White. Starting from day zero (T0), during the next four weeks, oral fluid samples were collected using cotton ropes, disposed for half-an-hour in the pens. Total protein and HPT concentrations were determined by spectrophotometry. Levels of AMY, CHE, and ADA were evaluated using commercial tests. Gelatinolytic activity of MMPs was estimated by sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE). For each analyte and group, results were given at all sampling points (T0-T4). The infected groups had detectable while the control had undetectable HPT levels. The infected gilts had lower activity of stress (AMY, CHE) and immunity (ADA) biomarkers, compared to the controls. Gelatinolytic analysis revealed MMP-2 and -9 signals in the PRRSV groups, and zymogen and active MMP-9 in the controls. Haptoglobin and MMP-2 and -9 in both of the infected groups contribute to the local salivary gland inflammatory response. Lower AMY and CHE activity in the oral fluid of PRRSV gilts could indicate altered salivary gland function that led to an unexpected drop in the stress markers, while lower ADA levels can be attributed to the suppressed immune response. All analyzed parameters could be valuable in testing porcine reaction to infection.",
publisher = "Beograd : Srpsko veterinarsko društvo, Sekcija za zoonoze",
journal = "XXVI Simpozijum epizootiologa i epidemiologa (XXVI Epizootiološki dani), Banja Koviljača, 10 - 12. april 2024",
title = "Biomarkeri stresa, inflamacije i imuniteta u oralnoj tečnosti nazimica sa reproduktivnim i respiratornim sindromom, Stress, inflammation and immunity oral fluid biomarkers in gilts with porcine reproductive and respiratory syndrome",
pages = "104-105",
url = "https://hdl.handle.net/21.15107/rcub_veterinar_3910"
}

Plut, J., Spariosu, K., Radaković, M., Francuski Andrić, J., Nemec Svete, A., Jamnikar Ciglenečki, U., Štukelj, M.,& Kovačević Filipović, M.. (2024). Biomarkeri stresa, inflamacije i imuniteta u oralnoj tečnosti nazimica sa reproduktivnim i respiratornim sindromom. in XXVI Simpozijum epizootiologa i epidemiologa (XXVI Epizootiološki dani), Banja Koviljača, 10 - 12. april 2024
Beograd : Srpsko veterinarsko društvo, Sekcija za zoonoze., 104-105.
https://hdl.handle.net/21.15107/rcub_veterinar_3910

Plut J, Spariosu K, Radaković M, Francuski Andrić J, Nemec Svete A, Jamnikar Ciglenečki U, Štukelj M, Kovačević Filipović M. Biomarkeri stresa, inflamacije i imuniteta u oralnoj tečnosti nazimica sa reproduktivnim i respiratornim sindromom. in XXVI Simpozijum epizootiologa i epidemiologa (XXVI Epizootiološki dani), Banja Koviljača, 10 - 12. april 2024. 2024;:104-105.
https://hdl.handle.net/21.15107/rcub_veterinar_3910 .

Plut, Jan, Spariosu, Kristina, Radaković, Milena, Francuski Andrić, Jelena, Nemec Svete, Alenka, Jamnikar Ciglenečki, Urška, Štukelj, Marina, Kovačević Filipović, Milica, "Biomarkeri stresa, inflamacije i imuniteta u oralnoj tečnosti nazimica sa reproduktivnim i respiratornim sindromom" in XXVI Simpozijum epizootiologa i epidemiologa (XXVI Epizootiološki dani), Banja Koviljača, 10 - 12. april 2024 (2024):104-105,
https://hdl.handle.net/21.15107/rcub_veterinar_3910 .

TY  - JOUR
AU  - Milanović, Zorana
AU  - Ilić Božović, Anja
AU  - Bojić-Trbojević, Žanka
AU  - Hajduković, Ljiljana
AU  - Francuski Andrić, Jelena
AU  - Kovačević Filipović, Milica
PY  - 2024
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/3631
AB  - Acute B. canis infection can lead to an acute phase reaction (APR) in dogs. The parasite invades red blood cells causing
anemia through immune-mediated hemolysis and possible erythropoietic suppression. A regenerative response of the
erythroid lineage during the babesiosis has not been described in extension. This research examines hematologic parameters
focusing on the absolute reticulocyte count and apolipoprotein A I (ApoA I) level on the day of admission and 14 days after
treatment with imidocarb-dipropionate in young (n=11) and adult (n=11) dogs naturally infected with B. canis. Metabolic
and inflammatory processes were characterized by analyzing protein and lipid profiles, as well as ApoA I at specified time
points. Automated analyzers were used to determine complete blood count and biochemical parameters, while ApoA I was
assessed using radioimmunoassay. The reticulocyte count was determined using a manual method by means of supravital
staining. Both young and adult dogs with acute B. canis infection showed non-regenerative anemia without difference.
Fourteen days after successful treatment with imidocarb-dipropionate, the anemia was corrected and a high reticulocyte
count was observed (p<0.05). This indicates that the erythroid regenerative response was efficient in young and adult dogs,
although vital signs, leukocyte count and triglyceride concentration suggest a more intense APR in young dogs. A decrease
in ApoA I in both groups 14 days after treatment (p<0.01) confirmed that this lipoprotein acts as a positive acute-phase
protein in acute B. canis infection in dogs, but further studies are needed to connect its role in erythroid lineage regeneration.
PB  - Saints Cyril and Methodius University of Skopje, Faculty of Veterinary Medicine
T2  - Macedonian Veterinary Review
T1  - Reticulocyte response in paired blood samples of Babesia canis infected young and adult dogs
VL  - 47
IS  - 1
DO  - 10.2478/macvetrev-2024-0011
ER  - 

@article{
author = "Milanović, Zorana and Ilić Božović, Anja and Bojić-Trbojević, Žanka and Hajduković, Ljiljana and Francuski Andrić, Jelena and Kovačević Filipović, Milica",
year = "2024",
abstract = "Acute B. canis infection can lead to an acute phase reaction (APR) in dogs. The parasite invades red blood cells causing
anemia through immune-mediated hemolysis and possible erythropoietic suppression. A regenerative response of the
erythroid lineage during the babesiosis has not been described in extension. This research examines hematologic parameters
focusing on the absolute reticulocyte count and apolipoprotein A I (ApoA I) level on the day of admission and 14 days after
treatment with imidocarb-dipropionate in young (n=11) and adult (n=11) dogs naturally infected with B. canis. Metabolic
and inflammatory processes were characterized by analyzing protein and lipid profiles, as well as ApoA I at specified time
points. Automated analyzers were used to determine complete blood count and biochemical parameters, while ApoA I was
assessed using radioimmunoassay. The reticulocyte count was determined using a manual method by means of supravital
staining. Both young and adult dogs with acute B. canis infection showed non-regenerative anemia without difference.
Fourteen days after successful treatment with imidocarb-dipropionate, the anemia was corrected and a high reticulocyte
count was observed (p<0.05). This indicates that the erythroid regenerative response was efficient in young and adult dogs,
although vital signs, leukocyte count and triglyceride concentration suggest a more intense APR in young dogs. A decrease
in ApoA I in both groups 14 days after treatment (p<0.01) confirmed that this lipoprotein acts as a positive acute-phase
protein in acute B. canis infection in dogs, but further studies are needed to connect its role in erythroid lineage regeneration.",
publisher = "Saints Cyril and Methodius University of Skopje, Faculty of Veterinary Medicine",
journal = "Macedonian Veterinary Review",
title = "Reticulocyte response in paired blood samples of Babesia canis infected young and adult dogs",
volume = "47",
number = "1",
doi = "10.2478/macvetrev-2024-0011"
}

Milanović, Z., Ilić Božović, A., Bojić-Trbojević, Ž., Hajduković, L., Francuski Andrić, J.,& Kovačević Filipović, M.. (2024). Reticulocyte response in paired blood samples of Babesia canis infected young and adult dogs. in Macedonian Veterinary Review
Saints Cyril and Methodius University of Skopje, Faculty of Veterinary Medicine., 47(1).
https://doi.org/10.2478/macvetrev-2024-0011

Milanović Z, Ilić Božović A, Bojić-Trbojević Ž, Hajduković L, Francuski Andrić J, Kovačević Filipović M. Reticulocyte response in paired blood samples of Babesia canis infected young and adult dogs. in Macedonian Veterinary Review. 2024;47(1).
doi:10.2478/macvetrev-2024-0011 .

Milanović, Zorana, Ilić Božović, Anja, Bojić-Trbojević, Žanka, Hajduković, Ljiljana, Francuski Andrić, Jelena, Kovačević Filipović, Milica, "Reticulocyte response in paired blood samples of Babesia canis infected young and adult dogs" in Macedonian Veterinary Review, 47, no. 1 (2024),
https://doi.org/10.2478/macvetrev-2024-0011 . .

TY  - CONF
AU  - Francuski Andrić, Jelena
AU  - Milošević, Strahinja
AU  - Davitkov, Dajana
AU  - Radaković, Milena
AU  - Davitkov, Darko
AU  - Magaš, Vladimir
AU  - Kovačević Filipović, Milica
PY  - 2024
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/3900
AB  - Introduction. Although thrombocytopenia is one of the hematological markers associated with babesia infection, it may not always be present1. Hematological indexes: the platelet-to-lymphocyte ratio (PLR) and the mean platelet volume-to-platelet ratio (MPV/PLT) may be more sensitive markers of an ongoing infection. Objective. To investigate PLR and MPV/PLT in dogs infected with Babesia spp. with and without thrombocytopenia. Methods. Babesia spp. PCR-positive client‐owned dogs were divided into two groups according to platelet number: thrombocytopenic (n=34) and non-thrombocytopenic (n=30). Clinically healthy PCR-negative dogs on Babesia spp. (n=41) served as a control. A complete blood count was obtained on IDEXX ProCyte hematology analyzer and the non-parametric statistics tests were performed in the SPSS program. Results. PCR-positive dogs on Babesia spp. had lower median platelet counts compared to PCR-negative dogs (P<0.01). The MPV and MPV/PLT were higher in thrombocytopenic than in non-thrombocytopenic (P<0.01) and control dogs (P<0.01). There was no difference in MPV between PCR-positive non-thrombocytopenic dogs and PCR-negative control, while the MPV/PLT ratio had differences (P<0.01). The median number of lymphocytes did not differ between the examined groups. The PLR was lower in the thrombocytopenic than in the non-thrombocytopenic (P<0.01) and control group (P<0.01). However, PLR did not differ between
PCR-positive and PCR-negative non-thrombocytopenic dogs. Conclusion. Ratios could be useful and should be explored further. The MPV/PLT has the potential to distinguish babesia-positive from babesia-negative dogs and its diagnostic value needs more attention.
C3  - XXI International Society for Animal Clinical Pathology Congress, ISACP 2024, Heraklion, 14 - 18 May 2024
T1  - Platelet-to-lymphocyte and mean platelet volume-to-platelet ratios in babesia infected dogs
SP  - 96
EP  - 97
UR  - https://hdl.handle.net/21.15107/rcub_veterinar_3900
ER  - 

@conference{
author = "Francuski Andrić, Jelena and Milošević, Strahinja and Davitkov, Dajana and Radaković, Milena and Davitkov, Darko and Magaš, Vladimir and Kovačević Filipović, Milica",
year = "2024",
abstract = "Introduction. Although thrombocytopenia is one of the hematological markers associated with babesia infection, it may not always be present1. Hematological indexes: the platelet-to-lymphocyte ratio (PLR) and the mean platelet volume-to-platelet ratio (MPV/PLT) may be more sensitive markers of an ongoing infection. Objective. To investigate PLR and MPV/PLT in dogs infected with Babesia spp. with and without thrombocytopenia. Methods. Babesia spp. PCR-positive client‐owned dogs were divided into two groups according to platelet number: thrombocytopenic (n=34) and non-thrombocytopenic (n=30). Clinically healthy PCR-negative dogs on Babesia spp. (n=41) served as a control. A complete blood count was obtained on IDEXX ProCyte hematology analyzer and the non-parametric statistics tests were performed in the SPSS program. Results. PCR-positive dogs on Babesia spp. had lower median platelet counts compared to PCR-negative dogs (P<0.01). The MPV and MPV/PLT were higher in thrombocytopenic than in non-thrombocytopenic (P<0.01) and control dogs (P<0.01). There was no difference in MPV between PCR-positive non-thrombocytopenic dogs and PCR-negative control, while the MPV/PLT ratio had differences (P<0.01). The median number of lymphocytes did not differ between the examined groups. The PLR was lower in the thrombocytopenic than in the non-thrombocytopenic (P<0.01) and control group (P<0.01). However, PLR did not differ between
PCR-positive and PCR-negative non-thrombocytopenic dogs. Conclusion. Ratios could be useful and should be explored further. The MPV/PLT has the potential to distinguish babesia-positive from babesia-negative dogs and its diagnostic value needs more attention.",
journal = "XXI International Society for Animal Clinical Pathology Congress, ISACP 2024, Heraklion, 14 - 18 May 2024",
title = "Platelet-to-lymphocyte and mean platelet volume-to-platelet ratios in babesia infected dogs",
pages = "96-97",
url = "https://hdl.handle.net/21.15107/rcub_veterinar_3900"
}

Francuski Andrić, J., Milošević, S., Davitkov, D., Radaković, M., Davitkov, D., Magaš, V.,& Kovačević Filipović, M.. (2024). Platelet-to-lymphocyte and mean platelet volume-to-platelet ratios in babesia infected dogs. in XXI International Society for Animal Clinical Pathology Congress, ISACP 2024, Heraklion, 14 - 18 May 2024, 96-97.
https://hdl.handle.net/21.15107/rcub_veterinar_3900

Francuski Andrić J, Milošević S, Davitkov D, Radaković M, Davitkov D, Magaš V, Kovačević Filipović M. Platelet-to-lymphocyte and mean platelet volume-to-platelet ratios in babesia infected dogs. in XXI International Society for Animal Clinical Pathology Congress, ISACP 2024, Heraklion, 14 - 18 May 2024. 2024;:96-97.
https://hdl.handle.net/21.15107/rcub_veterinar_3900 .

Francuski Andrić, Jelena, Milošević, Strahinja, Davitkov, Dajana, Radaković, Milena, Davitkov, Darko, Magaš, Vladimir, Kovačević Filipović, Milica, "Platelet-to-lymphocyte and mean platelet volume-to-platelet ratios in babesia infected dogs" in XXI International Society for Animal Clinical Pathology Congress, ISACP 2024, Heraklion, 14 - 18 May 2024 (2024):96-97,
https://hdl.handle.net/21.15107/rcub_veterinar_3900 .

TY  - CONF
AU  - Radaković, Milena
AU  - Janjić, Filip
AU  - Spariosu, Kristina
AU  - Marković, Lazar
AU  - Bulajić, Snežana
AU  - Kovačević Filipović, Milica
PY  - 2024
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/3899
AB  - Background: Given the stoic nature of donkeys, early clinical signs of illness may go unnoticed. Objective: Our study aimed to compare haemato-biochemical parameters and acute-phase proteins (APPs) as health status indicators in Balkan dairy donkeys in Serbia. Materials and methods: The study was conducted on two donkey farms: one located in an arid, hilly, forested area harboring 60 animals managed in a semiintensive system accounting for energy, protein, vitamin, and mineral requirements (Farm 1), and the other located in wetlands having 300 animals reared under the semi-extensive pasture-based system (Farm 2). Blood samples were collected from five (Farm 1) and 12 (Farm 2) clinically healthy randomly chosen jennies at the second half of gestational age, in the springtime. Haematology and biochemistry parameters were
determined using automated analysers, while haptoglobin (HP), ceruloplasmin (CP), and paraoxonase-1 (PON-1) were determined using spectrophotometry. Results: Haemoglobin (p=0.044), monocyte count (p=0.006), creatinine (p=0.027), urea (p=0.045), alkaline phosphatase (p=0.008), creatine kinase (p=0.020), and CP (p=0.018) were higher in Farm 1 than in Farm 2 donkeys. The values for HP and PON-1 did not differ between farms. All obtained values, including triglyceride concentration, matched reference intervals. Conclusions: Haemato-biochemical parameters and APPs indicated that despite differences that can be ascribed to the farm organization system, the donkeys did not have issues with metabolic or inflammatory diseases.
C3  - XXI International Society for Animal Clinical Pathology Congress, ISACP 2024, Heraklion, 14 - 18 May 2024
T1  - Assessment of health status of Balkan dairy donkeys in Serbia using haemato-biochemical profiles and acute phase proteins – A pilot study
SP  - 112
EP  - 113
UR  - https://hdl.handle.net/21.15107/rcub_veterinar_3899
ER  - 

@conference{
author = "Radaković, Milena and Janjić, Filip and Spariosu, Kristina and Marković, Lazar and Bulajić, Snežana and Kovačević Filipović, Milica",
year = "2024",
abstract = "Background: Given the stoic nature of donkeys, early clinical signs of illness may go unnoticed. Objective: Our study aimed to compare haemato-biochemical parameters and acute-phase proteins (APPs) as health status indicators in Balkan dairy donkeys in Serbia. Materials and methods: The study was conducted on two donkey farms: one located in an arid, hilly, forested area harboring 60 animals managed in a semiintensive system accounting for energy, protein, vitamin, and mineral requirements (Farm 1), and the other located in wetlands having 300 animals reared under the semi-extensive pasture-based system (Farm 2). Blood samples were collected from five (Farm 1) and 12 (Farm 2) clinically healthy randomly chosen jennies at the second half of gestational age, in the springtime. Haematology and biochemistry parameters were
determined using automated analysers, while haptoglobin (HP), ceruloplasmin (CP), and paraoxonase-1 (PON-1) were determined using spectrophotometry. Results: Haemoglobin (p=0.044), monocyte count (p=0.006), creatinine (p=0.027), urea (p=0.045), alkaline phosphatase (p=0.008), creatine kinase (p=0.020), and CP (p=0.018) were higher in Farm 1 than in Farm 2 donkeys. The values for HP and PON-1 did not differ between farms. All obtained values, including triglyceride concentration, matched reference intervals. Conclusions: Haemato-biochemical parameters and APPs indicated that despite differences that can be ascribed to the farm organization system, the donkeys did not have issues with metabolic or inflammatory diseases.",
journal = "XXI International Society for Animal Clinical Pathology Congress, ISACP 2024, Heraklion, 14 - 18 May 2024",
title = "Assessment of health status of Balkan dairy donkeys in Serbia using haemato-biochemical profiles and acute phase proteins – A pilot study",
pages = "112-113",
url = "https://hdl.handle.net/21.15107/rcub_veterinar_3899"
}

Radaković, M., Janjić, F., Spariosu, K., Marković, L., Bulajić, S.,& Kovačević Filipović, M.. (2024). Assessment of health status of Balkan dairy donkeys in Serbia using haemato-biochemical profiles and acute phase proteins – A pilot study. in XXI International Society for Animal Clinical Pathology Congress, ISACP 2024, Heraklion, 14 - 18 May 2024, 112-113.
https://hdl.handle.net/21.15107/rcub_veterinar_3899

Radaković M, Janjić F, Spariosu K, Marković L, Bulajić S, Kovačević Filipović M. Assessment of health status of Balkan dairy donkeys in Serbia using haemato-biochemical profiles and acute phase proteins – A pilot study. in XXI International Society for Animal Clinical Pathology Congress, ISACP 2024, Heraklion, 14 - 18 May 2024. 2024;:112-113.
https://hdl.handle.net/21.15107/rcub_veterinar_3899 .

Radaković, Milena, Janjić, Filip, Spariosu, Kristina, Marković, Lazar, Bulajić, Snežana, Kovačević Filipović, Milica, "Assessment of health status of Balkan dairy donkeys in Serbia using haemato-biochemical profiles and acute phase proteins – A pilot study" in XXI International Society for Animal Clinical Pathology Congress, ISACP 2024, Heraklion, 14 - 18 May 2024 (2024):112-113,
https://hdl.handle.net/21.15107/rcub_veterinar_3899 .

TY  - JOUR
AU  - Janjić, Filip
AU  - Spariosu, Kristina
AU  - Radaković, Milena
AU  - Francuski Andrić, Jelena
AU  - Beletić, Anđelo
AU  - Kovačević Filipović, Milica
PY  - 2024
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/3901
AB  - We tested the hypothesis that age, breed, and sex are related to hematology, biochemistry, acute phase proteins (APPs), seroreactivity and level of parasitemia in dogs with an acute phase response (APR) due to Babesia canis infection. The study enrolled 61 privately owned dogs that naturally acquired B. canis infection. Groups were formed according to the age: young dogs less than one year, and adult dogs more than one year old. Moreover, the group of males was compared to females and purebred to mixed breed dogs. Seroreactivity was tested with immunofluorescence antibody test, level of parasitemia with real-time polymerase chain reaction (real-time PCR), hematology, and biochemistry with automatic analyzers, serum amyloid A with enzyme-linked immunosorbent assay, fibrinogen with heat precipitation and ceruloplasmin and paraoxonase-1 with manual spectrophotometric methods. For protein separation agarose gel electrophoresis was used. The main changes in the whole population of B. canis-infected dogs were fever, pancytopenia, and change in APPs level. One-third of young, and 96% of adult dogs were seropositive (P < 0.001). The level of parasitemia was higher in the young dogs (P < 0.001). Erythroid lineage parameters (P < 0.01), and leukocytes (P < 0.05) were lower in the young, when compared to the adult dogs. Young dogs had lower total globulins (P < 0.001), β- and γ-globulins (P < 0.001), and higher α-globulins (P = 0.022) than adult dogs. Young dogs had higher concentrations of phosphate (P = 0.003) and cholesterol (P < 0.001) and lower amylase (P = 0.014) and lipase activity (P = 0.020) than adult ones. Male dogs had lower neutrophil count than females (P = 0.035), and purebred dogs had more band neutrophils than mixed breed dogs (P = 0.004). In conclusion, dogs with natural Babesia canis infection at a young age have more severe anemia and APR including leukopenia than adults. Male and purebred dogs might also have more severe APR than females and mix-breeds, as they have more pronounced changes related to the myeloid lineage.
PB  - Elsevier
T2  - Veterinary Parasitology
T1  - Age, sex and breed effect on laboratory parameters in natural Babesia canis infection
VL  - 329
SP  - 110197
DO  - 10.1016/j.vetpar.2024.110197
ER  - 

@article{
author = "Janjić, Filip and Spariosu, Kristina and Radaković, Milena and Francuski Andrić, Jelena and Beletić, Anđelo and Kovačević Filipović, Milica",
year = "2024",
abstract = "We tested the hypothesis that age, breed, and sex are related to hematology, biochemistry, acute phase proteins (APPs), seroreactivity and level of parasitemia in dogs with an acute phase response (APR) due to Babesia canis infection. The study enrolled 61 privately owned dogs that naturally acquired B. canis infection. Groups were formed according to the age: young dogs less than one year, and adult dogs more than one year old. Moreover, the group of males was compared to females and purebred to mixed breed dogs. Seroreactivity was tested with immunofluorescence antibody test, level of parasitemia with real-time polymerase chain reaction (real-time PCR), hematology, and biochemistry with automatic analyzers, serum amyloid A with enzyme-linked immunosorbent assay, fibrinogen with heat precipitation and ceruloplasmin and paraoxonase-1 with manual spectrophotometric methods. For protein separation agarose gel electrophoresis was used. The main changes in the whole population of B. canis-infected dogs were fever, pancytopenia, and change in APPs level. One-third of young, and 96% of adult dogs were seropositive (P < 0.001). The level of parasitemia was higher in the young dogs (P < 0.001). Erythroid lineage parameters (P < 0.01), and leukocytes (P < 0.05) were lower in the young, when compared to the adult dogs. Young dogs had lower total globulins (P < 0.001), β- and γ-globulins (P < 0.001), and higher α-globulins (P = 0.022) than adult dogs. Young dogs had higher concentrations of phosphate (P = 0.003) and cholesterol (P < 0.001) and lower amylase (P = 0.014) and lipase activity (P = 0.020) than adult ones. Male dogs had lower neutrophil count than females (P = 0.035), and purebred dogs had more band neutrophils than mixed breed dogs (P = 0.004). In conclusion, dogs with natural Babesia canis infection at a young age have more severe anemia and APR including leukopenia than adults. Male and purebred dogs might also have more severe APR than females and mix-breeds, as they have more pronounced changes related to the myeloid lineage.",
publisher = "Elsevier",
journal = "Veterinary Parasitology",
title = "Age, sex and breed effect on laboratory parameters in natural Babesia canis infection",
volume = "329",
pages = "110197",
doi = "10.1016/j.vetpar.2024.110197"
}

Janjić, F., Spariosu, K., Radaković, M., Francuski Andrić, J., Beletić, A.,& Kovačević Filipović, M.. (2024). Age, sex and breed effect on laboratory parameters in natural Babesia canis infection. in Veterinary Parasitology
Elsevier., 329, 110197.
https://doi.org/10.1016/j.vetpar.2024.110197

Janjić F, Spariosu K, Radaković M, Francuski Andrić J, Beletić A, Kovačević Filipović M. Age, sex and breed effect on laboratory parameters in natural Babesia canis infection. in Veterinary Parasitology. 2024;329:110197.
doi:10.1016/j.vetpar.2024.110197 .

Janjić, Filip, Spariosu, Kristina, Radaković, Milena, Francuski Andrić, Jelena, Beletić, Anđelo, Kovačević Filipović, Milica, "Age, sex and breed effect on laboratory parameters in natural Babesia canis infection" in Veterinary Parasitology, 329 (2024):110197,
https://doi.org/10.1016/j.vetpar.2024.110197 . .

TY  - JOUR
AU  - Ilić Božović, Anja
AU  - Đoković, Petar
AU  - Milanović, Zorana
AU  - Janjić, Filip
AU  - Spariosu, Kristina
AU  - Radonjić, Vladimir
AU  - Radaković, Milena
AU  - Magaš, Vladimir
AU  - Filipović, Dimitrije
AU  - Stanković, Sanja
AU  - Kovačević Filipović, Milica
AU  - Beletić, Andelo
PY  - 2023
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/2934
AB  - Homocysteine (Hcy) was investigated as the biomarker of cardiac, renal, and gastrointestinal disorders
in dogs. Data about low Hcy concentrations in the systemic inflammatory response syndrome raised a hypothesis that
Hcy in dogs could be a negative acute-phase reactant. This survey compared Hcy concentrations, serum amyloid A
(SAA), and the routine laboratory parameters between healthy (HD, N=6) and dogs with inflammation of different
extent: mild (dirofilariosis (DIR), N=31), moderate (babesiosis (BAB), N=12), and severe (pyometra (PYO), N=8).
The BAB and PYO groups had lower Hcy er than HD. Also, the levels in the PYO group were below those in the
DIRO group. SAA had the inverse pattern. Across the groups, Hcy and SAA levels correlated negatively (ρ = -0.502,
P<0.001). Hcy and SAA correlated with the erythrocyte count, hematocrit, hemoglobin and mean cellular hemoglobin
concentrations, and neutrophil count, with correlations being positive for Hcy and negative for SAA. Among all dogs,
hemoglobin was the only independent predictor of Hcy concentration. Hcy levels in canine infections, decreased as
acute-phase reaction (APR) intensified. Also, they were related with the hematology changes accompanying the APR.
Further studies will establish the clinical potential of these alterations.
PB  - Hellenic Veterinary Medical Society
T2  - Journal of the Hellenic Veterinary Medical Society
T1  - Could homocysteine represent a negative acute phase reactant in canine infections-a pilot study?
VL  - 74
IS  - 1
SP  - 5463
EP  - 5470
DO  - 10.12681/jhvms.29529
ER  - 

@article{
author = "Ilić Božović, Anja and Đoković, Petar and Milanović, Zorana and Janjić, Filip and Spariosu, Kristina and Radonjić, Vladimir and Radaković, Milena and Magaš, Vladimir and Filipović, Dimitrije and Stanković, Sanja and Kovačević Filipović, Milica and Beletić, Andelo",
year = "2023",
abstract = "Homocysteine (Hcy) was investigated as the biomarker of cardiac, renal, and gastrointestinal disorders
in dogs. Data about low Hcy concentrations in the systemic inflammatory response syndrome raised a hypothesis that
Hcy in dogs could be a negative acute-phase reactant. This survey compared Hcy concentrations, serum amyloid A
(SAA), and the routine laboratory parameters between healthy (HD, N=6) and dogs with inflammation of different
extent: mild (dirofilariosis (DIR), N=31), moderate (babesiosis (BAB), N=12), and severe (pyometra (PYO), N=8).
The BAB and PYO groups had lower Hcy er than HD. Also, the levels in the PYO group were below those in the
DIRO group. SAA had the inverse pattern. Across the groups, Hcy and SAA levels correlated negatively (ρ = -0.502,
P<0.001). Hcy and SAA correlated with the erythrocyte count, hematocrit, hemoglobin and mean cellular hemoglobin
concentrations, and neutrophil count, with correlations being positive for Hcy and negative for SAA. Among all dogs,
hemoglobin was the only independent predictor of Hcy concentration. Hcy levels in canine infections, decreased as
acute-phase reaction (APR) intensified. Also, they were related with the hematology changes accompanying the APR.
Further studies will establish the clinical potential of these alterations.",
publisher = "Hellenic Veterinary Medical Society",
journal = "Journal of the Hellenic Veterinary Medical Society",
title = "Could homocysteine represent a negative acute phase reactant in canine infections-a pilot study?",
volume = "74",
number = "1",
pages = "5463-5470",
doi = "10.12681/jhvms.29529"
}

Ilić Božović, A., Đoković, P., Milanović, Z., Janjić, F., Spariosu, K., Radonjić, V., Radaković, M., Magaš, V., Filipović, D., Stanković, S., Kovačević Filipović, M.,& Beletić, A.. (2023). Could homocysteine represent a negative acute phase reactant in canine infections-a pilot study?. in Journal of the Hellenic Veterinary Medical Society
Hellenic Veterinary Medical Society., 74(1), 5463-5470.
https://doi.org/10.12681/jhvms.29529

Ilić Božović A, Đoković P, Milanović Z, Janjić F, Spariosu K, Radonjić V, Radaković M, Magaš V, Filipović D, Stanković S, Kovačević Filipović M, Beletić A. Could homocysteine represent a negative acute phase reactant in canine infections-a pilot study?. in Journal of the Hellenic Veterinary Medical Society. 2023;74(1):5463-5470.
doi:10.12681/jhvms.29529 .

Ilić Božović, Anja, Đoković, Petar, Milanović, Zorana, Janjić, Filip, Spariosu, Kristina, Radonjić, Vladimir, Radaković, Milena, Magaš, Vladimir, Filipović, Dimitrije, Stanković, Sanja, Kovačević Filipović, Milica, Beletić, Andelo, "Could homocysteine represent a negative acute phase reactant in canine infections-a pilot study?" in Journal of the Hellenic Veterinary Medical Society, 74, no. 1 (2023):5463-5470,
https://doi.org/10.12681/jhvms.29529 . .

TY  - JOUR
AU  - Lužajić Božinovski, Tijana
AU  - Danilović Luković, Jelena
AU  - Nikolić, Anja
AU  - Radovanović, Anita
AU  - Marković, Danica
AU  - Kovačević Filipović, Milica
AU  - Vasić, Mirjana
AU  - Milošević, Ivan
PY  - 2023
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/3047
AB  - Epidermis stem cells have a crucial role through the processes of proliferation and
differentiation, to replace cells that are constantly lost during tissue turnover or
following injury. On the other hand, thyroid hormones regulate the proliferation and
differentiation of epidermal cells and thus significantly influence the homeostasis
of the skin. It is well known that maternal hypothyroidism during pregnancy leads
to impaired development of many organ systems in their offspring. However, there
is a lack of data about the influence of maternal subclinical hypothyroidism during
pregnancy and lactation on the development of the skin and its derivatives in the litter.
The aim of this study was to investigate the effects of maternal thyroid dysfunction on
the development of the skin and its derivatives in their offspring in the early postnatal
period. Antithyroid substance 6-n-propyl-2-thiouracil was added into the drinking water
to female Albino Oxfords rats from the beginning of pregnancy and during lactation,
with the aim to induce subclinical and overt form of hypothyroidism. Skin samples
were taken from male pups within twenty-four hours and seven days after birth. The
main findings of this investigation were that both forms of maternal hypothyroidism
lead to serious damage of the epidermis in pups in terms of pronounced hyperkeratosis
and reduction of the germinal layer along with a reduced number of hair follicles and
their delayed morphogenesis. Epidermal impairments were more pronounced in pups
with the overt form of hypothyroidism while offspring with the subclinical form had
impairments that were less pronounced and delayed in occurrence.
PB  - Beograd : Fakultet veterinarske medicine
T2  - Acta Veterinaria
T1  - Maternal subclinical and clinical hypothyroidism effects on rat offspring: a story of the skin and its derivatives
VL  - 73
IS  - 2
SP  - 231
EP  - 248
DO  - 10.2478/acve-2023-0018
ER  - 

@article{
author = "Lužajić Božinovski, Tijana and Danilović Luković, Jelena and Nikolić, Anja and Radovanović, Anita and Marković, Danica and Kovačević Filipović, Milica and Vasić, Mirjana and Milošević, Ivan",
year = "2023",
abstract = "Epidermis stem cells have a crucial role through the processes of proliferation and
differentiation, to replace cells that are constantly lost during tissue turnover or
following injury. On the other hand, thyroid hormones regulate the proliferation and
differentiation of epidermal cells and thus significantly influence the homeostasis
of the skin. It is well known that maternal hypothyroidism during pregnancy leads
to impaired development of many organ systems in their offspring. However, there
is a lack of data about the influence of maternal subclinical hypothyroidism during
pregnancy and lactation on the development of the skin and its derivatives in the litter.
The aim of this study was to investigate the effects of maternal thyroid dysfunction on
the development of the skin and its derivatives in their offspring in the early postnatal
period. Antithyroid substance 6-n-propyl-2-thiouracil was added into the drinking water
to female Albino Oxfords rats from the beginning of pregnancy and during lactation,
with the aim to induce subclinical and overt form of hypothyroidism. Skin samples
were taken from male pups within twenty-four hours and seven days after birth. The
main findings of this investigation were that both forms of maternal hypothyroidism
lead to serious damage of the epidermis in pups in terms of pronounced hyperkeratosis
and reduction of the germinal layer along with a reduced number of hair follicles and
their delayed morphogenesis. Epidermal impairments were more pronounced in pups
with the overt form of hypothyroidism while offspring with the subclinical form had
impairments that were less pronounced and delayed in occurrence.",
publisher = "Beograd : Fakultet veterinarske medicine",
journal = "Acta Veterinaria",
title = "Maternal subclinical and clinical hypothyroidism effects on rat offspring: a story of the skin and its derivatives",
volume = "73",
number = "2",
pages = "231-248",
doi = "10.2478/acve-2023-0018"
}

Lužajić Božinovski, T., Danilović Luković, J., Nikolić, A., Radovanović, A., Marković, D., Kovačević Filipović, M., Vasić, M.,& Milošević, I.. (2023). Maternal subclinical and clinical hypothyroidism effects on rat offspring: a story of the skin and its derivatives. in Acta Veterinaria
Beograd : Fakultet veterinarske medicine., 73(2), 231-248.
https://doi.org/10.2478/acve-2023-0018

Lužajić Božinovski T, Danilović Luković J, Nikolić A, Radovanović A, Marković D, Kovačević Filipović M, Vasić M, Milošević I. Maternal subclinical and clinical hypothyroidism effects on rat offspring: a story of the skin and its derivatives. in Acta Veterinaria. 2023;73(2):231-248.
doi:10.2478/acve-2023-0018 .

Lužajić Božinovski, Tijana, Danilović Luković, Jelena, Nikolić, Anja, Radovanović, Anita, Marković, Danica, Kovačević Filipović, Milica, Vasić, Mirjana, Milošević, Ivan, "Maternal subclinical and clinical hypothyroidism effects on rat offspring: a story of the skin and its derivatives" in Acta Veterinaria, 73, no. 2 (2023):231-248,
https://doi.org/10.2478/acve-2023-0018 . .

TY  - CONF
AU  - Kovačević Filipović, Milica
PY  - 2023
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/3243
AB  - Otkriće vitamina K i njegovih antagonista među kojima se ističe varfarin, je
smešteno u prvu polovinu 20. veka, na dva kontinenta i u nekoliko država. Ono
povezuje rad istraživača u poljoprivredi, veterini, biohemiji, fiziologiji i medicini.
Istorija ova dva otkrića je istorija dobro organizovanog i sistematskog rada, slučajnih,
neplaniranih nalaza, dobrog instinkta, nesrećnih okolnosti i srećnih ishoda. Rad na
unapređenju farmskog uzgoja živine koji se odvijao dvadesetih i tridesetih godina
prošlog veka u Kanadi, je podrazumevao optimizaciju ishrane, i doveo je do nastanka
eksperimentalnog modela za proučavanje faktora važnih za proces koagulacije, među
kojima je kao najznačajniji, u Danskoj, otkriven vitamin K. U istom periodu, masovno
uginjavanje goveda usled spontanog krvarenja, a zbog trovanja trulom detelinom, je u
Sjedinjenim Američkim Državama dovelo do otkrivanja dikumarola i njegovog
derivata varfarina, koji su antagonisti vitaminu K. Današnja medicina i biotehnologija
se ne mogu zamisliti bez vitamina K i varfarina. Vitamin K je dobio svoju ulogu u
sprečavanju sklonosti ka krvarenju kod bolesnika sa hepatopatijama, u neonatologiji,
i kao antidot prilikom trovanja varfarinom i drugim vitamin K zavisnim
antikoagulansima. Varfarin je prvobitno počeo da se koristi kao rodenticid, a potom je
dobio široku primenu u medicini, u patološkim stanjima koja zahtevaju smanjenje
rizika od tromboze. Pulmonalna tromboembolija, tromboza dubokih vena, atrijalna
fibrilacija i infarkt mikoarda ali i COVID-19 su neke od indikacija koje se ne mogu
terapirati bez antikoagulantnih lekova. Predviđa se da će tržište ovih lekova rasti zbog
sve starijeg svetskog stanovništva i suportivne terapije brojnih hroničnih bolesti.
PB  - Beograd : Srpsko veterinarsko društvo
C3  - 34. Savetovanje veterinara Srbije, Zlatibor, 07 - 10. septembar 2023
T1  - U tornadu otkrića – vitamin K i njegovi antagonisti
SP  - 468
EP  - 476
UR  - https://hdl.handle.net/21.15107/rcub_veterinar_3243
ER  - 

@conference{
author = "Kovačević Filipović, Milica",
year = "2023",
abstract = "Otkriće vitamina K i njegovih antagonista među kojima se ističe varfarin, je
smešteno u prvu polovinu 20. veka, na dva kontinenta i u nekoliko država. Ono
povezuje rad istraživača u poljoprivredi, veterini, biohemiji, fiziologiji i medicini.
Istorija ova dva otkrića je istorija dobro organizovanog i sistematskog rada, slučajnih,
neplaniranih nalaza, dobrog instinkta, nesrećnih okolnosti i srećnih ishoda. Rad na
unapređenju farmskog uzgoja živine koji se odvijao dvadesetih i tridesetih godina
prošlog veka u Kanadi, je podrazumevao optimizaciju ishrane, i doveo je do nastanka
eksperimentalnog modela za proučavanje faktora važnih za proces koagulacije, među
kojima je kao najznačajniji, u Danskoj, otkriven vitamin K. U istom periodu, masovno
uginjavanje goveda usled spontanog krvarenja, a zbog trovanja trulom detelinom, je u
Sjedinjenim Američkim Državama dovelo do otkrivanja dikumarola i njegovog
derivata varfarina, koji su antagonisti vitaminu K. Današnja medicina i biotehnologija
se ne mogu zamisliti bez vitamina K i varfarina. Vitamin K je dobio svoju ulogu u
sprečavanju sklonosti ka krvarenju kod bolesnika sa hepatopatijama, u neonatologiji,
i kao antidot prilikom trovanja varfarinom i drugim vitamin K zavisnim
antikoagulansima. Varfarin je prvobitno počeo da se koristi kao rodenticid, a potom je
dobio široku primenu u medicini, u patološkim stanjima koja zahtevaju smanjenje
rizika od tromboze. Pulmonalna tromboembolija, tromboza dubokih vena, atrijalna
fibrilacija i infarkt mikoarda ali i COVID-19 su neke od indikacija koje se ne mogu
terapirati bez antikoagulantnih lekova. Predviđa se da će tržište ovih lekova rasti zbog
sve starijeg svetskog stanovništva i suportivne terapije brojnih hroničnih bolesti.",
publisher = "Beograd : Srpsko veterinarsko društvo",
journal = "34. Savetovanje veterinara Srbije, Zlatibor, 07 - 10. septembar 2023",
title = "U tornadu otkrića – vitamin K i njegovi antagonisti",
pages = "468-476",
url = "https://hdl.handle.net/21.15107/rcub_veterinar_3243"
}

Kovačević Filipović, M.. (2023). U tornadu otkrića – vitamin K i njegovi antagonisti. in 34. Savetovanje veterinara Srbije, Zlatibor, 07 - 10. septembar 2023
Beograd : Srpsko veterinarsko društvo., 468-476.
https://hdl.handle.net/21.15107/rcub_veterinar_3243

Kovačević Filipović M. U tornadu otkrića – vitamin K i njegovi antagonisti. in 34. Savetovanje veterinara Srbije, Zlatibor, 07 - 10. septembar 2023. 2023;:468-476.
https://hdl.handle.net/21.15107/rcub_veterinar_3243 .

Kovačević Filipović, Milica, "U tornadu otkrića – vitamin K i njegovi antagonisti" in 34. Savetovanje veterinara Srbije, Zlatibor, 07 - 10. septembar 2023 (2023):468-476,
https://hdl.handle.net/21.15107/rcub_veterinar_3243 .

TY  - JOUR
AU  - Ilić, Milica
AU  - Ivković, Maša
AU  - Radaković, Milena
AU  - Spariosu, Kristina
AU  - Andrić, Nenad
AU  - Kovačević Filipović, Milica
AU  - Beletić, Anđelo
AU  - Francuski Andrić, Jelena
PY  - 2023
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/3254
AB  - Red blood cell osmotic fragility (RBCOF) refers to susceptibility to hemolysis in
vivo and in vitro. An increase in mean cellular hemoglobin concentration (MCHC)
also reflects in vivo and in vitro hemolysis. Common inflammatory infectious
diseases in dogs are often characterized by an increase in MCHC; however, it is
not known if there is a concomitant increase in RBCOF. The objective of this
study was to determine RBCOF in dogs with babesiosis, dirofilariosis,
parvovirosis, pyometra, and canine distemper and to investigate whether RBCOF
correlates with routine hematologic and biochemical parameters and lipoprotein
fractions. The diagnosis of canine infectious disease was made and complete
blood count, serum biochemical profiles, and lipoprotein electrophoresis were
determined according to current institutional protocols. RBCOF of healthy
control (n=8) and infected dogs (n=73) was measured with a phosphate-buffered
saline dilution test, and mean corpuscular fragility (MCF) was calculated. MCF
was increased in dirofilariosis, pyometra, and distemper; MCHC was increased
in all infected groups; HDL was decreased in babesiosis, pyometra, and
distemper compared with healthy controls. However, no correlation was found
between these parameters. On the other hand, hematological and biochemical
parameters, that are highly predictive of specific infections, correlated with MCF:
ALP for babesiosis (r=0.415, P=0.035), urea (r=-0.488, P=0.034) for
dirofilariosis, and leukocyte count (r=-0.820, P=0.046) for pyometra. Although
elevated MCHC levels in all samples from infected dogs indicate hemolysis,
RBCOF was elevated only in dirofilariosis, pyometra, and canine distemper,
leading to the conclusion that these apparently related phenomena are controlled
by different mechanisms.
PB  - Faculty of Veterinary Science, University of Agriculture, Faisalabad, Pakistan
T2  - Pakistan Veterinary Journal
T1  - Association of increased osmotic fragility of red blood cells with common systemic inflammatory diseases in dogs
VL  - 43
IS  - 3
SP  - 463
EP  - 469
DO  - 10.29261/pakvetj/2023.048
ER  - 

@article{
author = "Ilić, Milica and Ivković, Maša and Radaković, Milena and Spariosu, Kristina and Andrić, Nenad and Kovačević Filipović, Milica and Beletić, Anđelo and Francuski Andrić, Jelena",
year = "2023",
abstract = "Red blood cell osmotic fragility (RBCOF) refers to susceptibility to hemolysis in
vivo and in vitro. An increase in mean cellular hemoglobin concentration (MCHC)
also reflects in vivo and in vitro hemolysis. Common inflammatory infectious
diseases in dogs are often characterized by an increase in MCHC; however, it is
not known if there is a concomitant increase in RBCOF. The objective of this
study was to determine RBCOF in dogs with babesiosis, dirofilariosis,
parvovirosis, pyometra, and canine distemper and to investigate whether RBCOF
correlates with routine hematologic and biochemical parameters and lipoprotein
fractions. The diagnosis of canine infectious disease was made and complete
blood count, serum biochemical profiles, and lipoprotein electrophoresis were
determined according to current institutional protocols. RBCOF of healthy
control (n=8) and infected dogs (n=73) was measured with a phosphate-buffered
saline dilution test, and mean corpuscular fragility (MCF) was calculated. MCF
was increased in dirofilariosis, pyometra, and distemper; MCHC was increased
in all infected groups; HDL was decreased in babesiosis, pyometra, and
distemper compared with healthy controls. However, no correlation was found
between these parameters. On the other hand, hematological and biochemical
parameters, that are highly predictive of specific infections, correlated with MCF:
ALP for babesiosis (r=0.415, P=0.035), urea (r=-0.488, P=0.034) for
dirofilariosis, and leukocyte count (r=-0.820, P=0.046) for pyometra. Although
elevated MCHC levels in all samples from infected dogs indicate hemolysis,
RBCOF was elevated only in dirofilariosis, pyometra, and canine distemper,
leading to the conclusion that these apparently related phenomena are controlled
by different mechanisms.",
publisher = "Faculty of Veterinary Science, University of Agriculture, Faisalabad, Pakistan",
journal = "Pakistan Veterinary Journal",
title = "Association of increased osmotic fragility of red blood cells with common systemic inflammatory diseases in dogs",
volume = "43",
number = "3",
pages = "463-469",
doi = "10.29261/pakvetj/2023.048"
}

Ilić, M., Ivković, M., Radaković, M., Spariosu, K., Andrić, N., Kovačević Filipović, M., Beletić, A.,& Francuski Andrić, J.. (2023). Association of increased osmotic fragility of red blood cells with common systemic inflammatory diseases in dogs. in Pakistan Veterinary Journal
Faculty of Veterinary Science, University of Agriculture, Faisalabad, Pakistan., 43(3), 463-469.
https://doi.org/10.29261/pakvetj/2023.048

Ilić M, Ivković M, Radaković M, Spariosu K, Andrić N, Kovačević Filipović M, Beletić A, Francuski Andrić J. Association of increased osmotic fragility of red blood cells with common systemic inflammatory diseases in dogs. in Pakistan Veterinary Journal. 2023;43(3):463-469.
doi:10.29261/pakvetj/2023.048 .

Ilić, Milica, Ivković, Maša, Radaković, Milena, Spariosu, Kristina, Andrić, Nenad, Kovačević Filipović, Milica, Beletić, Anđelo, Francuski Andrić, Jelena, "Association of increased osmotic fragility of red blood cells with common systemic inflammatory diseases in dogs" in Pakistan Veterinary Journal, 43, no. 3 (2023):463-469,
https://doi.org/10.29261/pakvetj/2023.048 . .

TY  - CONF
AU  - Kovačević Filipović, Milica
AU  - Francuski Andrić, Jelena
AU  - Ilić Božović, Anja
AU  - Milčić Matić, Natalija
PY  - 2023
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/3310
AB  - Tankoigledna biopsija je sigurna i brza metoda koja je laka za izođenje.
Preporučuje se kao dijagnostička metoda za sve uvećane limfne čvorove, bilo da
se radi o uni- ili multicentričnim promenama kao i za sve kutane i subkutane
mase. Osim tankoiglene biopsije, po ekstirpaciji limfnog čvora, sa njegovog
preseka se može uraditi preparat – otisak.
Citološkim pregledom limfnog čvora se može utvrditi da li postoji
reaktivna hiperplazija, inflamatorne promena u tipu limfadenitisa, primarna
neoplazija limfnog čvora, infiltracija metastatskim tumorskim ćelijama ili
ekstramedularna hematopoeza.
Svaka od navedenih patoloških promena ima određene citološke
karakteristike. Preparat se pregleda na malom uveličanju da bi se uočila
celularnost, raspored ćelija, eventualne metastatske ćelije i optimalno mesto za
pregled. Potrebno je prepoznati tip pozadinskog (engl. background) materijala
primenjujući prvo malo, a potom i veliko uveličanje. To je materijal koji ne
predstavlja patološke ćelije ispitivanog tkiva/mase, već eritrocite koji dospevaju
na preparat oštećenjem krvnih sudova prilikom pravljenja preparata i/ili
ekstracelularni matriks, i/ili specifičan ekstraćelijski materijal koji može biti
tipičan za određeno tkivo i patološku promenu. Na primer, limfoglandularna
telašca predstavljaju delimično razložene delove apoptotičnih limfocita,
karakterističnog su izgleda i javljaju se u većem broju kod limfoma. Potom,
citološki nalaz uključuje prepoznavanje i opis tipova ćelija koje se vide, njihovu
morfologiju i međusobni odnos.
Osnovna pravila prilikom primene tankoiglene biopsije u pravljenju i
tumačenju citoloških preparata limfnih čvorova su sledeća: treba izbegavati da se
analiziraju submandibularni limfni čvorovi koji vrlo često imaju reaktivne promene. Ukoliko postoji generalizovana limfadenopatija treba uzeti uzorke iz
najmanje dva ili svih limfnih čvorova. Igla promera 22G treba da bude plasirana u
nekoliko pravaca i tangencionalno u odnosu na centar limfnog čvora. Kao
problem se može javiti aspiracija tkiva mimo limfnog čvora, a u
submandibularnom regionu su to često pljuvačne žlezde. Takođe, limitacija
citološke dijagnostike postoji kod sitnoćelijskih limfoma mačaka kada su limfociti
dobro diferencirani ili u slučaju fokalne distribucije metastaza. Stepen slaganja u
dijagnostici i prognozi citoloških interpretacija u odnosu na patohistološke zavisi
od tipa limfoma ili metastatske promene.
Kožni ili potkožni noduli su relativno česti problemi kod pasa i mačaka i
mogu imati različitu etiologiju. Dijagnostički pristup se sastoji od uzimanja
detaljne istorije bolesti, pre svega da li je promena nastala naglo ili je prisutna
duži vremenski period. Brzina rasta je takodje od velike važnosti, kao i sam
klinički izgled promene, kao i da li su dobro ograničene. Dubina lezije takođe
može biti od pomoći za izradu diferencijalne liste i dijagnostičkog plana. Ponovno
pojavljanje lezije u oblastima gde je izvršena operacija najčešće ukazuje na
neoplastičnu tvorevinu. Kod starijih pasa česte su potpuno benigne izrasline sa
karakterističnim izgledom. Pozitivan odgovor na antibiotike često ukazuje na
infektivnu etiologiju, ali ne isključuje mogućnost istovremenih bolesti kao što su
dermatomikoze ili tumori.
Prva diferencijacija u proceni nodula je da se utvrdi ili isključi postojanje
neoplastičnih promena za razliku od inflamatornih uzroka ili hiperplazije tkiva. U
te svrhe se koristi tankoiglena biopsija, kako bi se identifikovale prisutne ćelije. U
velikom broju slučajeva kliničar na osnovu mikroskopskog pregleda pripremljenih
pločica, može da proceni da li je u pitanju neoplazija, hiperplazija ili inflamatorni
proces. Na osnovu toga ili preuzima adekvatnu terapiju ili sprovodi dodatne
dijagnostičke postupke.
Sveobuhvatno gledano, sa pojedinim izuzecima, citologija predstavlja
brzu, jednostavnu i pouzdanu metodu za dijagnostiku inflamatornih i
neoplastičnih promena limfnih čvorova, kao i nodula na koži.
PB  - Beograd : Fakultet veterinarske medicine
C3  - 24. Regionalno savetovanje iz kliničke patologije i terapije malih životinja, Clinica veterinaria, Fruška gora, 8 - 10. jun 2023
T1  - Citologija u svakodnevnoj kliničkoj praksi (limfni čvorovi, kutane i subkutane mase)
VL  - 34
IS  - 33
UR  - https://hdl.handle.net/21.15107/rcub_veterinar_3310
ER  - 

@conference{
author = "Kovačević Filipović, Milica and Francuski Andrić, Jelena and Ilić Božović, Anja and Milčić Matić, Natalija",
year = "2023",
abstract = "Tankoigledna biopsija je sigurna i brza metoda koja je laka za izođenje.
Preporučuje se kao dijagnostička metoda za sve uvećane limfne čvorove, bilo da
se radi o uni- ili multicentričnim promenama kao i za sve kutane i subkutane
mase. Osim tankoiglene biopsije, po ekstirpaciji limfnog čvora, sa njegovog
preseka se može uraditi preparat – otisak.
Citološkim pregledom limfnog čvora se može utvrditi da li postoji
reaktivna hiperplazija, inflamatorne promena u tipu limfadenitisa, primarna
neoplazija limfnog čvora, infiltracija metastatskim tumorskim ćelijama ili
ekstramedularna hematopoeza.
Svaka od navedenih patoloških promena ima određene citološke
karakteristike. Preparat se pregleda na malom uveličanju da bi se uočila
celularnost, raspored ćelija, eventualne metastatske ćelije i optimalno mesto za
pregled. Potrebno je prepoznati tip pozadinskog (engl. background) materijala
primenjujući prvo malo, a potom i veliko uveličanje. To je materijal koji ne
predstavlja patološke ćelije ispitivanog tkiva/mase, već eritrocite koji dospevaju
na preparat oštećenjem krvnih sudova prilikom pravljenja preparata i/ili
ekstracelularni matriks, i/ili specifičan ekstraćelijski materijal koji može biti
tipičan za određeno tkivo i patološku promenu. Na primer, limfoglandularna
telašca predstavljaju delimično razložene delove apoptotičnih limfocita,
karakterističnog su izgleda i javljaju se u većem broju kod limfoma. Potom,
citološki nalaz uključuje prepoznavanje i opis tipova ćelija koje se vide, njihovu
morfologiju i međusobni odnos.
Osnovna pravila prilikom primene tankoiglene biopsije u pravljenju i
tumačenju citoloških preparata limfnih čvorova su sledeća: treba izbegavati da se
analiziraju submandibularni limfni čvorovi koji vrlo često imaju reaktivne promene. Ukoliko postoji generalizovana limfadenopatija treba uzeti uzorke iz
najmanje dva ili svih limfnih čvorova. Igla promera 22G treba da bude plasirana u
nekoliko pravaca i tangencionalno u odnosu na centar limfnog čvora. Kao
problem se može javiti aspiracija tkiva mimo limfnog čvora, a u
submandibularnom regionu su to često pljuvačne žlezde. Takođe, limitacija
citološke dijagnostike postoji kod sitnoćelijskih limfoma mačaka kada su limfociti
dobro diferencirani ili u slučaju fokalne distribucije metastaza. Stepen slaganja u
dijagnostici i prognozi citoloških interpretacija u odnosu na patohistološke zavisi
od tipa limfoma ili metastatske promene.
Kožni ili potkožni noduli su relativno česti problemi kod pasa i mačaka i
mogu imati različitu etiologiju. Dijagnostički pristup se sastoji od uzimanja
detaljne istorije bolesti, pre svega da li je promena nastala naglo ili je prisutna
duži vremenski period. Brzina rasta je takodje od velike važnosti, kao i sam
klinički izgled promene, kao i da li su dobro ograničene. Dubina lezije takođe
može biti od pomoći za izradu diferencijalne liste i dijagnostičkog plana. Ponovno
pojavljanje lezije u oblastima gde je izvršena operacija najčešće ukazuje na
neoplastičnu tvorevinu. Kod starijih pasa česte su potpuno benigne izrasline sa
karakterističnim izgledom. Pozitivan odgovor na antibiotike često ukazuje na
infektivnu etiologiju, ali ne isključuje mogućnost istovremenih bolesti kao što su
dermatomikoze ili tumori.
Prva diferencijacija u proceni nodula je da se utvrdi ili isključi postojanje
neoplastičnih promena za razliku od inflamatornih uzroka ili hiperplazije tkiva. U
te svrhe se koristi tankoiglena biopsija, kako bi se identifikovale prisutne ćelije. U
velikom broju slučajeva kliničar na osnovu mikroskopskog pregleda pripremljenih
pločica, može da proceni da li je u pitanju neoplazija, hiperplazija ili inflamatorni
proces. Na osnovu toga ili preuzima adekvatnu terapiju ili sprovodi dodatne
dijagnostičke postupke.
Sveobuhvatno gledano, sa pojedinim izuzecima, citologija predstavlja
brzu, jednostavnu i pouzdanu metodu za dijagnostiku inflamatornih i
neoplastičnih promena limfnih čvorova, kao i nodula na koži.",
publisher = "Beograd : Fakultet veterinarske medicine",
journal = "24. Regionalno savetovanje iz kliničke patologije i terapije malih životinja, Clinica veterinaria, Fruška gora, 8 - 10. jun 2023",
title = "Citologija u svakodnevnoj kliničkoj praksi (limfni čvorovi, kutane i subkutane mase)",
volume = "34",
number = "33",
url = "https://hdl.handle.net/21.15107/rcub_veterinar_3310"
}

Kovačević Filipović, M., Francuski Andrić, J., Ilić Božović, A.,& Milčić Matić, N.. (2023). Citologija u svakodnevnoj kliničkoj praksi (limfni čvorovi, kutane i subkutane mase). in 24. Regionalno savetovanje iz kliničke patologije i terapije malih životinja, Clinica veterinaria, Fruška gora, 8 - 10. jun 2023
Beograd : Fakultet veterinarske medicine., 34(33).
https://hdl.handle.net/21.15107/rcub_veterinar_3310

Kovačević Filipović M, Francuski Andrić J, Ilić Božović A, Milčić Matić N. Citologija u svakodnevnoj kliničkoj praksi (limfni čvorovi, kutane i subkutane mase). in 24. Regionalno savetovanje iz kliničke patologije i terapije malih životinja, Clinica veterinaria, Fruška gora, 8 - 10. jun 2023. 2023;34(33).
https://hdl.handle.net/21.15107/rcub_veterinar_3310 .

Kovačević Filipović, Milica, Francuski Andrić, Jelena, Ilić Božović, Anja, Milčić Matić, Natalija, "Citologija u svakodnevnoj kliničkoj praksi (limfni čvorovi, kutane i subkutane mase)" in 24. Regionalno savetovanje iz kliničke patologije i terapije malih životinja, Clinica veterinaria, Fruška gora, 8 - 10. jun 2023, 34, no. 33 (2023),
https://hdl.handle.net/21.15107/rcub_veterinar_3310 .

TY  - JOUR
AU  - Radaković, Milena
AU  - Francuski Andrić, Jelena
AU  - Spariosu, Kristina
AU  - Vejnović, Branislav
AU  - Kovačević Filipović, Milica
AU  - Andrić, Nenad
PY  - 2023
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/3391
AB  - Oxidative stress plays an important role in pathogenesis of idiopathic epilepsy (IE). Although IE is the most
common neurological condition, oxidant–antioxidant status in epileptic dogs is still unknown. The aim of this
study is to evaluate the serum oxidant-antioxidant status in dogs with newly diagnosed IE. The status in 15 dogs
with IE and 15 healthy dogs is estimated through spectrophotometric determination of two oxidant markers:
advanced oxidation protein products-albumin index (AOPP) and thiobarbituric acid reactive substances
(TBARS); and three antioxidant markers: total thiols (R-SH) level, glutathione (GSH) level, and paraoxonase-1
(PON-1) activity. Also, butyrylcholinesterase (BChE) activity is assessed in both groups of dogs. Higher AOPP
is observed in the dogs with newly diagnosed IE, while TBARS level shows no difference when compared to the
healthy dogs. In contrast, lower levels of antioxidants (R-SH, GSH, and PON-1) and BChE activity are found in the
dogs with IE. No significant differences are observed in the oxidant and antioxidant markers and BChE activity
across the investigated IE cases with focal and generalized seizures. Our findings provide evidence that dogs with
IE are characterized by an impaired serum oxidant–antioxidant balance and lower BChE activity, which may
contribute to a better understanding of IE pathogenesis.
PB  - Elsevier
T2  - Research in Veterinary Science
T1  - Serum oxidant–antioxidant status and butyrylcholinesterase activity in dogs with idiopathic epilepsy – A pilot study
VL  - 165
SP  - 105076
DO  - 10.1016/j.rvsc.2023.105076
ER  - 

@article{
author = "Radaković, Milena and Francuski Andrić, Jelena and Spariosu, Kristina and Vejnović, Branislav and Kovačević Filipović, Milica and Andrić, Nenad",
year = "2023",
abstract = "Oxidative stress plays an important role in pathogenesis of idiopathic epilepsy (IE). Although IE is the most
common neurological condition, oxidant–antioxidant status in epileptic dogs is still unknown. The aim of this
study is to evaluate the serum oxidant-antioxidant status in dogs with newly diagnosed IE. The status in 15 dogs
with IE and 15 healthy dogs is estimated through spectrophotometric determination of two oxidant markers:
advanced oxidation protein products-albumin index (AOPP) and thiobarbituric acid reactive substances
(TBARS); and three antioxidant markers: total thiols (R-SH) level, glutathione (GSH) level, and paraoxonase-1
(PON-1) activity. Also, butyrylcholinesterase (BChE) activity is assessed in both groups of dogs. Higher AOPP
is observed in the dogs with newly diagnosed IE, while TBARS level shows no difference when compared to the
healthy dogs. In contrast, lower levels of antioxidants (R-SH, GSH, and PON-1) and BChE activity are found in the
dogs with IE. No significant differences are observed in the oxidant and antioxidant markers and BChE activity
across the investigated IE cases with focal and generalized seizures. Our findings provide evidence that dogs with
IE are characterized by an impaired serum oxidant–antioxidant balance and lower BChE activity, which may
contribute to a better understanding of IE pathogenesis.",
publisher = "Elsevier",
journal = "Research in Veterinary Science",
title = "Serum oxidant–antioxidant status and butyrylcholinesterase activity in dogs with idiopathic epilepsy – A pilot study",
volume = "165",
pages = "105076",
doi = "10.1016/j.rvsc.2023.105076"
}

Radaković, M., Francuski Andrić, J., Spariosu, K., Vejnović, B., Kovačević Filipović, M.,& Andrić, N.. (2023). Serum oxidant–antioxidant status and butyrylcholinesterase activity in dogs with idiopathic epilepsy – A pilot study. in Research in Veterinary Science
Elsevier., 165, 105076.
https://doi.org/10.1016/j.rvsc.2023.105076

Radaković M, Francuski Andrić J, Spariosu K, Vejnović B, Kovačević Filipović M, Andrić N. Serum oxidant–antioxidant status and butyrylcholinesterase activity in dogs with idiopathic epilepsy – A pilot study. in Research in Veterinary Science. 2023;165:105076.
doi:10.1016/j.rvsc.2023.105076 .

Radaković, Milena, Francuski Andrić, Jelena, Spariosu, Kristina, Vejnović, Branislav, Kovačević Filipović, Milica, Andrić, Nenad, "Serum oxidant–antioxidant status and butyrylcholinesterase activity in dogs with idiopathic epilepsy – A pilot study" in Research in Veterinary Science, 165 (2023):105076,
https://doi.org/10.1016/j.rvsc.2023.105076 . .

TY  - CONF
AU  - Kovačević-Filipović, Milica
AU  - Francuski Andrić, Jelena
AU  - Radaković, Milena
AU  - Spariosu, Kristina
PY  - 2022
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/2429
AB  - Procenjuje se da prevalenca bubrežnih bolesti u ukupnoj populaciji pasa i mačka iznosi oko 0,5% do 3%, ali da u gerijatrijskoj populaciji prevalenca hronične bubrežne bolesti dostiže čak 80%. Osim
rasne predispozije i starosti, kao faktori rizika navode se hiperkalcemija, bolesti srca, cistitis, urolitijaza, hipertireoidizam, periodontalni i
metabolički poremećaji i hronične ili perzistentne infekcije. Stalni monitoring funkcije bubrega je neophodan da bi se uvela odgovarajuća
terapija, koja može značajno da uspori progresivan tok gubitka funkcije bubrega koji prati bubrežne bolesti. Klasični markeri gubitka funkcije bubrega su koncentracija uree i kreatinina u serumu. Njihova koncentracija raste tek kada je rezervni kapacitet bubrega potrošen, odnosno kada propadne 75% svih nefrona. Na radionici će biti objašnjen
i demonstriran značaj 1) simetričnog dimetilarginina (SDMA) kao novog, osetljivijeg markera premećaja funkcije bubrega, potom 2) značaj
određivanja odnosa proteina i kreatinina u mokraći, kao i 3) potencijal
primene elektroforeze na gelu poliakrilamida za detekciju proteina u
urinu sa ciljem diferencijalne dijagnostike poremećaja funkcije glomerula, odnosno tubula.
AB  - It is estimated that the prevalence of kidney disease in the total population of dogs
and cats is about 0.5% to 3%, but in the geriatric population the prevalence of chronic
kidney disease reaches as much as 80%. In addition to breed predisposition and age,
hypercalcemia, heart disease, periodontal problems, cystitis, urolithiasis, hyperthyroidism,
metabolic disorders, and chronic or persistent infections are listed as risk factors.
Continuous monitoring of the renal function is important for timely and appropriate therapy
managment. Appropriate therapy can significantly slow down the progressive course of
renal disease. The classic markers to test the loss of kidney function are concentration
of urea and creatinine in the serum. Their concentration increases only when the reserve
capacity of the kidneys is lost, ie. when 75% of all nephrons fail. The workshop will explain
and demonstrate the importance of 1) symmetric dimethylarginine (SDMA) as a new, more
sensitive marker of renal dysfunction, 2) determining the urine protein-creatinine ratio, as
well as 3) differential diagnosis of glomerular or tubular proteinuria using polyacrilamid gel
electrophoresis.
PB  - Fakultet veterinarske medicine, Centar za izdavačku delatnost i promet učila
C3  - Zbornik radova - XLIII seminar inovacija znanja veterinara
T1  - Novi laboratorijski parametri dijagnostike poremećaja funkcije bubrega kod pasa i mačaka
T1  - New laboratory parameters for the diagnostic algorithm of kidney function disorders in dogs and cats
SP  - 191
EP  - 202
UR  - https://hdl.handle.net/21.15107/rcub_veterinar_2429
ER  - 

@conference{
author = "Kovačević-Filipović, Milica and Francuski Andrić, Jelena and Radaković, Milena and Spariosu, Kristina",
year = "2022",
abstract = "Procenjuje se da prevalenca bubrežnih bolesti u ukupnoj populaciji pasa i mačka iznosi oko 0,5% do 3%, ali da u gerijatrijskoj populaciji prevalenca hronične bubrežne bolesti dostiže čak 80%. Osim
rasne predispozije i starosti, kao faktori rizika navode se hiperkalcemija, bolesti srca, cistitis, urolitijaza, hipertireoidizam, periodontalni i
metabolički poremećaji i hronične ili perzistentne infekcije. Stalni monitoring funkcije bubrega je neophodan da bi se uvela odgovarajuća
terapija, koja može značajno da uspori progresivan tok gubitka funkcije bubrega koji prati bubrežne bolesti. Klasični markeri gubitka funkcije bubrega su koncentracija uree i kreatinina u serumu. Njihova koncentracija raste tek kada je rezervni kapacitet bubrega potrošen, odnosno kada propadne 75% svih nefrona. Na radionici će biti objašnjen
i demonstriran značaj 1) simetričnog dimetilarginina (SDMA) kao novog, osetljivijeg markera premećaja funkcije bubrega, potom 2) značaj
određivanja odnosa proteina i kreatinina u mokraći, kao i 3) potencijal
primene elektroforeze na gelu poliakrilamida za detekciju proteina u
urinu sa ciljem diferencijalne dijagnostike poremećaja funkcije glomerula, odnosno tubula., It is estimated that the prevalence of kidney disease in the total population of dogs
and cats is about 0.5% to 3%, but in the geriatric population the prevalence of chronic
kidney disease reaches as much as 80%. In addition to breed predisposition and age,
hypercalcemia, heart disease, periodontal problems, cystitis, urolithiasis, hyperthyroidism,
metabolic disorders, and chronic or persistent infections are listed as risk factors.
Continuous monitoring of the renal function is important for timely and appropriate therapy
managment. Appropriate therapy can significantly slow down the progressive course of
renal disease. The classic markers to test the loss of kidney function are concentration
of urea and creatinine in the serum. Their concentration increases only when the reserve
capacity of the kidneys is lost, ie. when 75% of all nephrons fail. The workshop will explain
and demonstrate the importance of 1) symmetric dimethylarginine (SDMA) as a new, more
sensitive marker of renal dysfunction, 2) determining the urine protein-creatinine ratio, as
well as 3) differential diagnosis of glomerular or tubular proteinuria using polyacrilamid gel
electrophoresis.",
publisher = "Fakultet veterinarske medicine, Centar za izdavačku delatnost i promet učila",
journal = "Zbornik radova - XLIII seminar inovacija znanja veterinara",
title = "Novi laboratorijski parametri dijagnostike poremećaja funkcije bubrega kod pasa i mačaka, New laboratory parameters for the diagnostic algorithm of kidney function disorders in dogs and cats",
pages = "191-202",
url = "https://hdl.handle.net/21.15107/rcub_veterinar_2429"
}

Kovačević-Filipović, M., Francuski Andrić, J., Radaković, M.,& Spariosu, K.. (2022). Novi laboratorijski parametri dijagnostike poremećaja funkcije bubrega kod pasa i mačaka. in Zbornik radova - XLIII seminar inovacija znanja veterinara
Fakultet veterinarske medicine, Centar za izdavačku delatnost i promet učila., 191-202.
https://hdl.handle.net/21.15107/rcub_veterinar_2429

Kovačević-Filipović M, Francuski Andrić J, Radaković M, Spariosu K. Novi laboratorijski parametri dijagnostike poremećaja funkcije bubrega kod pasa i mačaka. in Zbornik radova - XLIII seminar inovacija znanja veterinara. 2022;:191-202.
https://hdl.handle.net/21.15107/rcub_veterinar_2429 .

Kovačević-Filipović, Milica, Francuski Andrić, Jelena, Radaković, Milena, Spariosu, Kristina, "Novi laboratorijski parametri dijagnostike poremećaja funkcije bubrega kod pasa i mačaka" in Zbornik radova - XLIII seminar inovacija znanja veterinara (2022):191-202,
https://hdl.handle.net/21.15107/rcub_veterinar_2429 .

TY  - CONF
AU  - Francuski Andrić, Jelena
AU  - Magaš, Vladimir
AU  - Ilić Božović, Anja
AU  - Spariosu, Kristina
AU  - Radaković, Milena
AU  - Sukara, Ratko
AU  - Tomanović, Snežana
AU  - Kovačević Filipović, Milica
PY  - 2022
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/2614
C3  - 24th Annual Congress of the European Society of Veterinary Clinical Pathology, Belgrade, Serbia, October 5-8, 2022
T1  - Three clinical cases of Babesia gibsoni infection in Serbia should we worry?
SP  - 74
EP  - 75
UR  - https://hdl.handle.net/21.15107/rcub_veterinar_2614
ER  - 

@conference{
author = "Francuski Andrić, Jelena and Magaš, Vladimir and Ilić Božović, Anja and Spariosu, Kristina and Radaković, Milena and Sukara, Ratko and Tomanović, Snežana and Kovačević Filipović, Milica",
year = "2022",
journal = "24th Annual Congress of the European Society of Veterinary Clinical Pathology, Belgrade, Serbia, October 5-8, 2022",
title = "Three clinical cases of Babesia gibsoni infection in Serbia should we worry?",
pages = "74-75",
url = "https://hdl.handle.net/21.15107/rcub_veterinar_2614"
}

Francuski Andrić, J., Magaš, V., Ilić Božović, A., Spariosu, K., Radaković, M., Sukara, R., Tomanović, S.,& Kovačević Filipović, M.. (2022). Three clinical cases of Babesia gibsoni infection in Serbia should we worry?. in 24th Annual Congress of the European Society of Veterinary Clinical Pathology, Belgrade, Serbia, October 5-8, 2022, 74-75.
https://hdl.handle.net/21.15107/rcub_veterinar_2614

Francuski Andrić J, Magaš V, Ilić Božović A, Spariosu K, Radaković M, Sukara R, Tomanović S, Kovačević Filipović M. Three clinical cases of Babesia gibsoni infection in Serbia should we worry?. in 24th Annual Congress of the European Society of Veterinary Clinical Pathology, Belgrade, Serbia, October 5-8, 2022. 2022;:74-75.
https://hdl.handle.net/21.15107/rcub_veterinar_2614 .

Francuski Andrić, Jelena, Magaš, Vladimir, Ilić Božović, Anja, Spariosu, Kristina, Radaković, Milena, Sukara, Ratko, Tomanović, Snežana, Kovačević Filipović, Milica, "Three clinical cases of Babesia gibsoni infection in Serbia should we worry?" in 24th Annual Congress of the European Society of Veterinary Clinical Pathology, Belgrade, Serbia, October 5-8, 2022 (2022):74-75,
https://hdl.handle.net/21.15107/rcub_veterinar_2614 .

TY  - CONF
AU  - Spariosu, Kristina
AU  - Marković, Lazar
AU  - Radaković, Milena
AU  - Francuski Andrić, Jelena
AU  - Beletić, Anđelo
AU  - Kovačević Filipović, Milica
PY  - 2022
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/2613
C3  - 24th Annual Congress of the European Society of Veterinary Clinical Pathology, Belgrade, Serbia, October 5-8, 2022
T1  - Septic versus non-septic canine babesiosis: is there a difference in leukocyte function?
SP  - 70
EP  - 71
UR  - https://hdl.handle.net/21.15107/rcub_veterinar_2613
ER  - 

@conference{
author = "Spariosu, Kristina and Marković, Lazar and Radaković, Milena and Francuski Andrić, Jelena and Beletić, Anđelo and Kovačević Filipović, Milica",
year = "2022",
journal = "24th Annual Congress of the European Society of Veterinary Clinical Pathology, Belgrade, Serbia, October 5-8, 2022",
title = "Septic versus non-septic canine babesiosis: is there a difference in leukocyte function?",
pages = "70-71",
url = "https://hdl.handle.net/21.15107/rcub_veterinar_2613"
}

Spariosu, K., Marković, L., Radaković, M., Francuski Andrić, J., Beletić, A.,& Kovačević Filipović, M.. (2022). Septic versus non-septic canine babesiosis: is there a difference in leukocyte function?. in 24th Annual Congress of the European Society of Veterinary Clinical Pathology, Belgrade, Serbia, October 5-8, 2022, 70-71.
https://hdl.handle.net/21.15107/rcub_veterinar_2613

Spariosu K, Marković L, Radaković M, Francuski Andrić J, Beletić A, Kovačević Filipović M. Septic versus non-septic canine babesiosis: is there a difference in leukocyte function?. in 24th Annual Congress of the European Society of Veterinary Clinical Pathology, Belgrade, Serbia, October 5-8, 2022. 2022;:70-71.
https://hdl.handle.net/21.15107/rcub_veterinar_2613 .

Spariosu, Kristina, Marković, Lazar, Radaković, Milena, Francuski Andrić, Jelena, Beletić, Anđelo, Kovačević Filipović, Milica, "Septic versus non-septic canine babesiosis: is there a difference in leukocyte function?" in 24th Annual Congress of the European Society of Veterinary Clinical Pathology, Belgrade, Serbia, October 5-8, 2022 (2022):70-71,
https://hdl.handle.net/21.15107/rcub_veterinar_2613 .

TY  - CONF
AU  - Radaković, Milena
AU  - Spariosu, Kristina
AU  - Janjić, Filip
AU  - Francuski Andrić, Jelena
AU  - Beletić, Anđelo
AU  - Milanović, Svetlana
AU  - Kovačević Filipović, Milica
PY  - 2022
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/2612
C3  - 24th Annual Congress of the European Society of Veterinary Clinical Pathology, Belgrade, Serbia, October 5-8, 2022
T1  - Oxidative stress in canine babesiosis
SP  - 80
EP  - 81
UR  - https://hdl.handle.net/21.15107/rcub_veterinar_2612
ER  - 

@conference{
author = "Radaković, Milena and Spariosu, Kristina and Janjić, Filip and Francuski Andrić, Jelena and Beletić, Anđelo and Milanović, Svetlana and Kovačević Filipović, Milica",
year = "2022",
journal = "24th Annual Congress of the European Society of Veterinary Clinical Pathology, Belgrade, Serbia, October 5-8, 2022",
title = "Oxidative stress in canine babesiosis",
pages = "80-81",
url = "https://hdl.handle.net/21.15107/rcub_veterinar_2612"
}

Radaković, M., Spariosu, K., Janjić, F., Francuski Andrić, J., Beletić, A., Milanović, S.,& Kovačević Filipović, M.. (2022). Oxidative stress in canine babesiosis. in 24th Annual Congress of the European Society of Veterinary Clinical Pathology, Belgrade, Serbia, October 5-8, 2022, 80-81.
https://hdl.handle.net/21.15107/rcub_veterinar_2612

Radaković M, Spariosu K, Janjić F, Francuski Andrić J, Beletić A, Milanović S, Kovačević Filipović M. Oxidative stress in canine babesiosis. in 24th Annual Congress of the European Society of Veterinary Clinical Pathology, Belgrade, Serbia, October 5-8, 2022. 2022;:80-81.
https://hdl.handle.net/21.15107/rcub_veterinar_2612 .

Radaković, Milena, Spariosu, Kristina, Janjić, Filip, Francuski Andrić, Jelena, Beletić, Anđelo, Milanović, Svetlana, Kovačević Filipović, Milica, "Oxidative stress in canine babesiosis" in 24th Annual Congress of the European Society of Veterinary Clinical Pathology, Belgrade, Serbia, October 5-8, 2022 (2022):80-81,
https://hdl.handle.net/21.15107/rcub_veterinar_2612 .

TY  - CONF
AU  - Milanović, Zorana
AU  - Ilić Božović, Anja
AU  - Beletić, Anđelo
AU  - Radaković, Milena
AU  - Kovačević Filipović, Milica
PY  - 2022
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/2611
C3  - 24th Annual Congress of the European Society of Veterinary Clinical Pathology, Belgrade, Serbia, October 5-8, 2022.
T1  - Inflammation in canine babesiosis: what to expect in asymptomatic dogs and dogs with coinfections?
SP  - 76
SP  - 77
UR  - https://hdl.handle.net/21.15107/rcub_veterinar_2611
ER  - 

@conference{
author = "Milanović, Zorana and Ilić Božović, Anja and Beletić, Anđelo and Radaković, Milena and Kovačević Filipović, Milica",
year = "2022",
journal = "24th Annual Congress of the European Society of Veterinary Clinical Pathology, Belgrade, Serbia, October 5-8, 2022.",
title = "Inflammation in canine babesiosis: what to expect in asymptomatic dogs and dogs with coinfections?",
pages = "76-77",
url = "https://hdl.handle.net/21.15107/rcub_veterinar_2611"
}

Milanović, Z., Ilić Božović, A., Beletić, A., Radaković, M.,& Kovačević Filipović, M.. (2022). Inflammation in canine babesiosis: what to expect in asymptomatic dogs and dogs with coinfections?. in 24th Annual Congress of the European Society of Veterinary Clinical Pathology, Belgrade, Serbia, October 5-8, 2022., 76.
https://hdl.handle.net/21.15107/rcub_veterinar_2611

Milanović Z, Ilić Božović A, Beletić A, Radaković M, Kovačević Filipović M. Inflammation in canine babesiosis: what to expect in asymptomatic dogs and dogs with coinfections?. in 24th Annual Congress of the European Society of Veterinary Clinical Pathology, Belgrade, Serbia, October 5-8, 2022.. 2022;:76.
https://hdl.handle.net/21.15107/rcub_veterinar_2611 .

Milanović, Zorana, Ilić Božović, Anja, Beletić, Anđelo, Radaković, Milena, Kovačević Filipović, Milica, "Inflammation in canine babesiosis: what to expect in asymptomatic dogs and dogs with coinfections?" in 24th Annual Congress of the European Society of Veterinary Clinical Pathology, Belgrade, Serbia, October 5-8, 2022. (2022):76,
https://hdl.handle.net/21.15107/rcub_veterinar_2611 .

TY  - JOUR
AU  - Antić, Milutin
AU  - Beletić, Anđelo
AU  - Radaković, Milena
AU  - Spariosu, Kristina
AU  - Stanković, Sanja
AU  - Trailović, Dragiša
AU  - Kovačević Filipović, Milica
PY  - 2022
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/2718
AB  - Progressive tissue injury in canine leishmaniosis (CL) is related to the deposition of
immune complexes, which induces vasculitis and leads to endothelial dysfunction.
Homocysteine (Hcy) increase may worsen endothelial dysfunction, but data concerning
its concentration in different CL stages and links to the acute phase response and
oxidative stress are missing. We compared Hcy levels between dogs with mild (N=24)
and moderate CL without treatment (N=17) and treated with anti-Leishmania drugs
and vitamin B supplements (N=9). Dogs with moderate CL, regardless of therapy
administration, had more distinct clinical signs, lower erythron values, and a higher level
of acute-phase proteins (APPs), IgG against Leishmania spp., urea and creatinine, than
dogs with mild CL. Hcy values did not differ between stages, but treated dogs had the
lowest levels of Hcy. An inverse relationship existed between Hcy and the CL stage,
therapy, levels of IgG, and clinical pathology data. The only positive relationship existed
between Hcy and the erythron state. The disease stage and therapeutic intervention
were not related to the oxidative stress level, except in the case of paraoxonase-1/
Hcy ratio, indicating favorable conditions for antioxidative defense in treated dogs. In
conclusion, changes in Hcy levels indicated its possible involvement with endothelial
dysfunction and inverse relationship to tissue injury evaluated by APPs. Finally, Hcy
might be an early marker of favorable conditions for endothelium recovery in CL
PB  - Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd
T2  - Acta Veterinaria
T1  - Homocysteine concentration in the serum of dogs naturally infected with Leishmania spp. – association with the stage of the disease, therapy, and clinical pathology data
VL  - 72
IS  - 3
SP  - 309
EP  - 323
DO  - 10.2478/acve-2022-0025
ER  - 

@article{
author = "Antić, Milutin and Beletić, Anđelo and Radaković, Milena and Spariosu, Kristina and Stanković, Sanja and Trailović, Dragiša and Kovačević Filipović, Milica",
year = "2022",
abstract = "Progressive tissue injury in canine leishmaniosis (CL) is related to the deposition of
immune complexes, which induces vasculitis and leads to endothelial dysfunction.
Homocysteine (Hcy) increase may worsen endothelial dysfunction, but data concerning
its concentration in different CL stages and links to the acute phase response and
oxidative stress are missing. We compared Hcy levels between dogs with mild (N=24)
and moderate CL without treatment (N=17) and treated with anti-Leishmania drugs
and vitamin B supplements (N=9). Dogs with moderate CL, regardless of therapy
administration, had more distinct clinical signs, lower erythron values, and a higher level
of acute-phase proteins (APPs), IgG against Leishmania spp., urea and creatinine, than
dogs with mild CL. Hcy values did not differ between stages, but treated dogs had the
lowest levels of Hcy. An inverse relationship existed between Hcy and the CL stage,
therapy, levels of IgG, and clinical pathology data. The only positive relationship existed
between Hcy and the erythron state. The disease stage and therapeutic intervention
were not related to the oxidative stress level, except in the case of paraoxonase-1/
Hcy ratio, indicating favorable conditions for antioxidative defense in treated dogs. In
conclusion, changes in Hcy levels indicated its possible involvement with endothelial
dysfunction and inverse relationship to tissue injury evaluated by APPs. Finally, Hcy
might be an early marker of favorable conditions for endothelium recovery in CL",
publisher = "Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd",
journal = "Acta Veterinaria",
title = "Homocysteine concentration in the serum of dogs naturally infected with Leishmania spp. – association with the stage of the disease, therapy, and clinical pathology data",
volume = "72",
number = "3",
pages = "309-323",
doi = "10.2478/acve-2022-0025"
}

Antić, M., Beletić, A., Radaković, M., Spariosu, K., Stanković, S., Trailović, D.,& Kovačević Filipović, M.. (2022). Homocysteine concentration in the serum of dogs naturally infected with Leishmania spp. – association with the stage of the disease, therapy, and clinical pathology data. in Acta Veterinaria
Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd., 72(3), 309-323.
https://doi.org/10.2478/acve-2022-0025

Antić M, Beletić A, Radaković M, Spariosu K, Stanković S, Trailović D, Kovačević Filipović M. Homocysteine concentration in the serum of dogs naturally infected with Leishmania spp. – association with the stage of the disease, therapy, and clinical pathology data. in Acta Veterinaria. 2022;72(3):309-323.
doi:10.2478/acve-2022-0025 .

Antić, Milutin, Beletić, Anđelo, Radaković, Milena, Spariosu, Kristina, Stanković, Sanja, Trailović, Dragiša, Kovačević Filipović, Milica, "Homocysteine concentration in the serum of dogs naturally infected with Leishmania spp. – association with the stage of the disease, therapy, and clinical pathology data" in Acta Veterinaria, 72, no. 3 (2022):309-323,
https://doi.org/10.2478/acve-2022-0025 . .

TY  - JOUR
AU  - Janjić, Filip
AU  - Beletić, Anđelo
AU  - Radaković, Milena
AU  - Spariosu, Kristina
AU  - Diklić, Miloš
AU  - Francuski Andrić, Jelena
AU  - Radonjić, Vladimir
AU  - Ajtić, Jelena
AU  - Kovačević-Filipović, Milica
PY  - 2022
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/2338
AB  - The highest number of acute Babesia canis cases in dogs is recorded over the February-May (Feb-May) period, which also represents the optimal climate conditions for tick activity in Belgrade, Serbia. A possibility that the acute phase response is more intense in dogs developing the disease in the Feb-May period compared with the response in other time periods of the year was tested. A total of 63 client-owned dogs with acute B. canis infection were enrolled and the routine hematology and biochemistry parameters-serum amyloid A (SAA), IgG against B. canis, level of parasitemia, ceruloplasmin (CER), paraoxonase-1 (PON-1), and fibrinogen-were measured. Acute phase indexes (API) were calculated as (SAA×CER)/(Iron×PON-1) and (SAA×CER)/(Albumin×Iron). Statistics included Kruskal-Wallis test and logistic regression analysis. The results showed that in the Feb-May period, the following parameters were lower: creatinine, albumin, iron, and level of parasitemia. Furthermore, increased API values were more probable in the Feb-May than in the other periods. Together, higher acute phase response intensity and presumptive hemodilution in the Feb-May period indicate a more acute course of B. canis infection than in other time periods of the year.
PB  - Springer
T2  - International Journal of Biometeorology
T1  - Seasonal differences in the intensity of acute phase response in dogs infected with Babesia canis
DO  - 10.1007/s00484-021-02228-4
ER  - 

@article{
author = "Janjić, Filip and Beletić, Anđelo and Radaković, Milena and Spariosu, Kristina and Diklić, Miloš and Francuski Andrić, Jelena and Radonjić, Vladimir and Ajtić, Jelena and Kovačević-Filipović, Milica",
year = "2022",
abstract = "The highest number of acute Babesia canis cases in dogs is recorded over the February-May (Feb-May) period, which also represents the optimal climate conditions for tick activity in Belgrade, Serbia. A possibility that the acute phase response is more intense in dogs developing the disease in the Feb-May period compared with the response in other time periods of the year was tested. A total of 63 client-owned dogs with acute B. canis infection were enrolled and the routine hematology and biochemistry parameters-serum amyloid A (SAA), IgG against B. canis, level of parasitemia, ceruloplasmin (CER), paraoxonase-1 (PON-1), and fibrinogen-were measured. Acute phase indexes (API) were calculated as (SAA×CER)/(Iron×PON-1) and (SAA×CER)/(Albumin×Iron). Statistics included Kruskal-Wallis test and logistic regression analysis. The results showed that in the Feb-May period, the following parameters were lower: creatinine, albumin, iron, and level of parasitemia. Furthermore, increased API values were more probable in the Feb-May than in the other periods. Together, higher acute phase response intensity and presumptive hemodilution in the Feb-May period indicate a more acute course of B. canis infection than in other time periods of the year.",
publisher = "Springer",
journal = "International Journal of Biometeorology",
title = "Seasonal differences in the intensity of acute phase response in dogs infected with Babesia canis",
doi = "10.1007/s00484-021-02228-4"
}

Janjić, F., Beletić, A., Radaković, M., Spariosu, K., Diklić, M., Francuski Andrić, J., Radonjić, V., Ajtić, J.,& Kovačević-Filipović, M.. (2022). Seasonal differences in the intensity of acute phase response in dogs infected with Babesia canis. in International Journal of Biometeorology
Springer..
https://doi.org/10.1007/s00484-021-02228-4

Janjić F, Beletić A, Radaković M, Spariosu K, Diklić M, Francuski Andrić J, Radonjić V, Ajtić J, Kovačević-Filipović M. Seasonal differences in the intensity of acute phase response in dogs infected with Babesia canis. in International Journal of Biometeorology. 2022;.
doi:10.1007/s00484-021-02228-4 .

Janjić, Filip, Beletić, Anđelo, Radaković, Milena, Spariosu, Kristina, Diklić, Miloš, Francuski Andrić, Jelena, Radonjić, Vladimir, Ajtić, Jelena, Kovačević-Filipović, Milica, "Seasonal differences in the intensity of acute phase response in dogs infected with Babesia canis" in International Journal of Biometeorology (2022),
https://doi.org/10.1007/s00484-021-02228-4 . .

TY  - CONF
AU  - Janjić, Filip
AU  - Beletić, Anđelo
AU  - Radaković, Milena
AU  - Spariosu, Kristina
AU  - Francuski Andrić, Jelena
AU  - Ajtić, Jelena
AU  - Kovačević-Filipović, Milica
PY  - 2022
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/2488
AB  - Background: Canine babesiosis is a disease with a seasonal character. We have
previously observed that in Belgrade, the capital of the Republic of Serbia, 60% of
cases with the acute-phase response (APR) give a notable maximum between mid-
February and May, the so-called “high season”. The other two peak seasons with
less pronounced maxima are in winter, from January to mid-February, and in
autumn, from October to December. Objectives: Based on clinical observations, we
postulate that dogs infected with B. canis in the “high season” develop a more
intense APR than dogs in the other two seasons. Material and Methods: To test this
hypothesis, we compare the relative parasite load and the level of acute-phase
proteins and reactants, their indexes (calculated as a combination of
concentrations of fast and slow positive, and fast and slow negative acute phase
reactants), as well as the concentration of coagulation factors, complete blood
count, and biochemistry among dogs that developed the disease in the autumn,
winter, and “high season”. Results: The relative parasite load is the lowest, and APR
Indexes are the highest in dogs infected in “high season”. These findings are
accompanied by relatively low creatinine and urea, implying that dogs in “high
season” had hemodilution, thus further suggesting short incubation. Unlike other
acute-phase proteins, fibrinogen showed the lowest concentration in “high
season”. Conclusion: Future research will help unveil the connection between
more intense APR and relatively low parasite load and fibrinogen concentration.
C3  - 24th Annual Congress of the European Society of Veterinary Clinical Pathology, Belgrade, Serbia, October 5-8
T1  - Canine babesiosis in different seasons - a fertile ground for multiple questions
SP  - 78
EP  - 79
UR  - https://hdl.handle.net/21.15107/rcub_veterinar_2488
ER  - 

@conference{
author = "Janjić, Filip and Beletić, Anđelo and Radaković, Milena and Spariosu, Kristina and Francuski Andrić, Jelena and Ajtić, Jelena and Kovačević-Filipović, Milica",
year = "2022",
abstract = "Background: Canine babesiosis is a disease with a seasonal character. We have
previously observed that in Belgrade, the capital of the Republic of Serbia, 60% of
cases with the acute-phase response (APR) give a notable maximum between mid-
February and May, the so-called “high season”. The other two peak seasons with
less pronounced maxima are in winter, from January to mid-February, and in
autumn, from October to December. Objectives: Based on clinical observations, we
postulate that dogs infected with B. canis in the “high season” develop a more
intense APR than dogs in the other two seasons. Material and Methods: To test this
hypothesis, we compare the relative parasite load and the level of acute-phase
proteins and reactants, their indexes (calculated as a combination of
concentrations of fast and slow positive, and fast and slow negative acute phase
reactants), as well as the concentration of coagulation factors, complete blood
count, and biochemistry among dogs that developed the disease in the autumn,
winter, and “high season”. Results: The relative parasite load is the lowest, and APR
Indexes are the highest in dogs infected in “high season”. These findings are
accompanied by relatively low creatinine and urea, implying that dogs in “high
season” had hemodilution, thus further suggesting short incubation. Unlike other
acute-phase proteins, fibrinogen showed the lowest concentration in “high
season”. Conclusion: Future research will help unveil the connection between
more intense APR and relatively low parasite load and fibrinogen concentration.",
journal = "24th Annual Congress of the European Society of Veterinary Clinical Pathology, Belgrade, Serbia, October 5-8",
title = "Canine babesiosis in different seasons - a fertile ground for multiple questions",
pages = "78-79",
url = "https://hdl.handle.net/21.15107/rcub_veterinar_2488"
}

Janjić, F., Beletić, A., Radaković, M., Spariosu, K., Francuski Andrić, J., Ajtić, J.,& Kovačević-Filipović, M.. (2022). Canine babesiosis in different seasons - a fertile ground for multiple questions. in 24th Annual Congress of the European Society of Veterinary Clinical Pathology, Belgrade, Serbia, October 5-8, 78-79.
https://hdl.handle.net/21.15107/rcub_veterinar_2488

Janjić F, Beletić A, Radaković M, Spariosu K, Francuski Andrić J, Ajtić J, Kovačević-Filipović M. Canine babesiosis in different seasons - a fertile ground for multiple questions. in 24th Annual Congress of the European Society of Veterinary Clinical Pathology, Belgrade, Serbia, October 5-8. 2022;:78-79.
https://hdl.handle.net/21.15107/rcub_veterinar_2488 .

Janjić, Filip, Beletić, Anđelo, Radaković, Milena, Spariosu, Kristina, Francuski Andrić, Jelena, Ajtić, Jelena, Kovačević-Filipović, Milica, "Canine babesiosis in different seasons - a fertile ground for multiple questions" in 24th Annual Congress of the European Society of Veterinary Clinical Pathology, Belgrade, Serbia, October 5-8 (2022):78-79,
https://hdl.handle.net/21.15107/rcub_veterinar_2488 .

TY  - CONF
AU  - Kovačević-Filipović, Milica
AU  - Spariosu, Kristina
AU  - Janjić, Filip
AU  - Radaković, Milena
AU  - Ilić Božović, Anja
AU  - Davitkov, Darko
AU  - Francuski Andrić, Jelena
PY  - 2022
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/2501
AB  - Prema mehanizmu nastanka, anemije se klasifikuju na
hemoličke i hemoragijske i anemije koje nastaju usled
poremećaja na nivou kostne srži. Hemoličke i hemoragijske
anemije su najčešće praćene ubrzanom eritropoezom i jakim
regenerativnim odgovorom, koji se ogleda u značajnom
porastu broja retikulocita. Suprotno, poremećaji na nivou
kostne srži, koji najčešće uključuju različite oblike
imunosupresije, inhibiciju proliferacije eritroidnih progenitora
i/ili nedostatak nutritivnih faktora, dijagnostikuju se kao
neregenerativne anemije, koje se analizom krvne slike
prepoznaju na osnovu relativno malog broja retikulocita.
PB  - Fakultet veterinarske medicine Univerziteta u Beogradu
C3  - Clinica veterinaria zbornik predavanja Dvadeset trećeg regionalnog savetovanja iz kliničke patologije i terapije malih životinja, Fruška gora, 09-11. jun
T1  - Kliničko-patološki pristup dijagnostici anemija različite etiologije
SP  - 27
SP  - 29
EP  - 31
UR  - https://hdl.handle.net/21.15107/rcub_veterinar_2501
ER  - 

@conference{
author = "Kovačević-Filipović, Milica and Spariosu, Kristina and Janjić, Filip and Radaković, Milena and Ilić Božović, Anja and Davitkov, Darko and Francuski Andrić, Jelena",
year = "2022",
abstract = "Prema mehanizmu nastanka, anemije se klasifikuju na
hemoličke i hemoragijske i anemije koje nastaju usled
poremećaja na nivou kostne srži. Hemoličke i hemoragijske
anemije su najčešće praćene ubrzanom eritropoezom i jakim
regenerativnim odgovorom, koji se ogleda u značajnom
porastu broja retikulocita. Suprotno, poremećaji na nivou
kostne srži, koji najčešće uključuju različite oblike
imunosupresije, inhibiciju proliferacije eritroidnih progenitora
i/ili nedostatak nutritivnih faktora, dijagnostikuju se kao
neregenerativne anemije, koje se analizom krvne slike
prepoznaju na osnovu relativno malog broja retikulocita.",
publisher = "Fakultet veterinarske medicine Univerziteta u Beogradu",
journal = "Clinica veterinaria zbornik predavanja Dvadeset trećeg regionalnog savetovanja iz kliničke patologije i terapije malih životinja, Fruška gora, 09-11. jun",
title = "Kliničko-patološki pristup dijagnostici anemija različite etiologije",
pages = "27-29-31",
url = "https://hdl.handle.net/21.15107/rcub_veterinar_2501"
}

Kovačević-Filipović, M., Spariosu, K., Janjić, F., Radaković, M., Ilić Božović, A., Davitkov, D.,& Francuski Andrić, J.. (2022). Kliničko-patološki pristup dijagnostici anemija različite etiologije. in Clinica veterinaria zbornik predavanja Dvadeset trećeg regionalnog savetovanja iz kliničke patologije i terapije malih životinja, Fruška gora, 09-11. jun
Fakultet veterinarske medicine Univerziteta u Beogradu., 27-31.
https://hdl.handle.net/21.15107/rcub_veterinar_2501

Kovačević-Filipović M, Spariosu K, Janjić F, Radaković M, Ilić Božović A, Davitkov D, Francuski Andrić J. Kliničko-patološki pristup dijagnostici anemija različite etiologije. in Clinica veterinaria zbornik predavanja Dvadeset trećeg regionalnog savetovanja iz kliničke patologije i terapije malih životinja, Fruška gora, 09-11. jun. 2022;:27-31.
https://hdl.handle.net/21.15107/rcub_veterinar_2501 .

Kovačević-Filipović, Milica, Spariosu, Kristina, Janjić, Filip, Radaković, Milena, Ilić Božović, Anja, Davitkov, Darko, Francuski Andrić, Jelena, "Kliničko-patološki pristup dijagnostici anemija različite etiologije" in Clinica veterinaria zbornik predavanja Dvadeset trećeg regionalnog savetovanja iz kliničke patologije i terapije malih životinja, Fruška gora, 09-11. jun (2022):27-31,
https://hdl.handle.net/21.15107/rcub_veterinar_2501 .

TY  - CONF
AU  - Marković, Lazar
AU  - Đoković, Stefan
AU  - Radaković, Milena
AU  - Francuski Andrić, Jelena
AU  - Milošević, Ivan
AU  - Beletić, Anđelo
AU  - Kovačević Filipović, Milica
PY  - 2022
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/2590
AB  - Inflamatorni i degenerativni procesi na zglobovima konja se mogu postepeno razvijati,
pri čemu klinički znaci patoloških promena često nisu vidljivi. Cilj ove studije je
bio da se na osnovu rutinskog pregleda sinovijalne tečnosti (ST) poreklom iz metakarpo/
metatarzofalangealnih (MCP/MTP) zglobova radnih konja, koji su bili upućeni na
klanje i njenih biohemijskih karakteristika utvrdi da li je postojala lokalna inflamacija.
Studija je sprovedena na 6 konja starosti 3 do 12 godina (medijana 8), odnosno 24
MCP/MTP zgloba. Post mortem, iz svakog zgloba je uzorkovana ST. Kliničkim pregledom
pre klanja, nisu uočene promene u izgledu i funkciji mišićno-skeletnog sistema.
Urađen je rutinski pregled ST kojim je opisana boja, prozirnost, viskoznost i broj ćelija.
Određena je koncentracija sledećih biohemijskih parametara: ukupnih proteina,
albumina, aktivnost alkalne fosfataze (ALP), aspartat aminotransferaze (AST), kreatin
kinaze (CK), kao i koncentracije haptoglobina (Hp) i ceruloplazmina (Cp). Kod svih
uzoraka, ST je bila bistra, providna, viskozna i blede do bledo žute boje. Najmlađi konj,
star tri godine, je u sva četiri pregledana zgloba imao ukupan broj ćelija 200-890/μL,
što odgovara fiziološkim vrednostima. Dva konja su imala povećan broj ćelija na jednom,
odnosno dva zgloba (1 400-2 560/μL), dok su tri konja imala promene na sva četiri
zgloba (1 100-2 200/μL). Ispitivani biohemijski parametri se nisu razlikovali u uzorcima
ST iz zglobova sa ukupnim brojem ćelija u okviru fizioloških vrednosti i onih kod
kojih je broj ćelija bio povećan. Pozitivne, umerene korelacije su postojale između koncentracije
proteina i aktivnosti ALP, koncentracije proteina i albumina, aktivnosti AST
i CK. Ispitivanjem ST radnih konja, dokazano je da inflamatorne promene u MCP/MTP
zglobovima nisu prisutne. Nalaz povećanog broja ćelija u ST bez inflamatornih promena
zahteva dodatna ispitivanja.
PB  - Beograd : Srpsko veterinarsko društvo
C3  - 33. Savetovanje Veterinara Srbije, Zlatibor, 08 - 11. septembra, 2022
T1  - Laboratorijski profil sinovijalne tečnosti kod šest radnih konja različite starosti
SP  - 294
EP  - 300
UR  - https://hdl.handle.net/21.15107/rcub_veterinar_2590
ER  - 

@conference{
author = "Marković, Lazar and Đoković, Stefan and Radaković, Milena and Francuski Andrić, Jelena and Milošević, Ivan and Beletić, Anđelo and Kovačević Filipović, Milica",
year = "2022",
abstract = "Inflamatorni i degenerativni procesi na zglobovima konja se mogu postepeno razvijati,
pri čemu klinički znaci patoloških promena često nisu vidljivi. Cilj ove studije je
bio da se na osnovu rutinskog pregleda sinovijalne tečnosti (ST) poreklom iz metakarpo/
metatarzofalangealnih (MCP/MTP) zglobova radnih konja, koji su bili upućeni na
klanje i njenih biohemijskih karakteristika utvrdi da li je postojala lokalna inflamacija.
Studija je sprovedena na 6 konja starosti 3 do 12 godina (medijana 8), odnosno 24
MCP/MTP zgloba. Post mortem, iz svakog zgloba je uzorkovana ST. Kliničkim pregledom
pre klanja, nisu uočene promene u izgledu i funkciji mišićno-skeletnog sistema.
Urađen je rutinski pregled ST kojim je opisana boja, prozirnost, viskoznost i broj ćelija.
Određena je koncentracija sledećih biohemijskih parametara: ukupnih proteina,
albumina, aktivnost alkalne fosfataze (ALP), aspartat aminotransferaze (AST), kreatin
kinaze (CK), kao i koncentracije haptoglobina (Hp) i ceruloplazmina (Cp). Kod svih
uzoraka, ST je bila bistra, providna, viskozna i blede do bledo žute boje. Najmlađi konj,
star tri godine, je u sva četiri pregledana zgloba imao ukupan broj ćelija 200-890/μL,
što odgovara fiziološkim vrednostima. Dva konja su imala povećan broj ćelija na jednom,
odnosno dva zgloba (1 400-2 560/μL), dok su tri konja imala promene na sva četiri
zgloba (1 100-2 200/μL). Ispitivani biohemijski parametri se nisu razlikovali u uzorcima
ST iz zglobova sa ukupnim brojem ćelija u okviru fizioloških vrednosti i onih kod
kojih je broj ćelija bio povećan. Pozitivne, umerene korelacije su postojale između koncentracije
proteina i aktivnosti ALP, koncentracije proteina i albumina, aktivnosti AST
i CK. Ispitivanjem ST radnih konja, dokazano je da inflamatorne promene u MCP/MTP
zglobovima nisu prisutne. Nalaz povećanog broja ćelija u ST bez inflamatornih promena
zahteva dodatna ispitivanja.",
publisher = "Beograd : Srpsko veterinarsko društvo",
journal = "33. Savetovanje Veterinara Srbije, Zlatibor, 08 - 11. septembra, 2022",
title = "Laboratorijski profil sinovijalne tečnosti kod šest radnih konja različite starosti",
pages = "294-300",
url = "https://hdl.handle.net/21.15107/rcub_veterinar_2590"
}

Marković, L., Đoković, S., Radaković, M., Francuski Andrić, J., Milošević, I., Beletić, A.,& Kovačević Filipović, M.. (2022). Laboratorijski profil sinovijalne tečnosti kod šest radnih konja različite starosti. in 33. Savetovanje Veterinara Srbije, Zlatibor, 08 - 11. septembra, 2022
Beograd : Srpsko veterinarsko društvo., 294-300.
https://hdl.handle.net/21.15107/rcub_veterinar_2590

Marković L, Đoković S, Radaković M, Francuski Andrić J, Milošević I, Beletić A, Kovačević Filipović M. Laboratorijski profil sinovijalne tečnosti kod šest radnih konja različite starosti. in 33. Savetovanje Veterinara Srbije, Zlatibor, 08 - 11. septembra, 2022. 2022;:294-300.
https://hdl.handle.net/21.15107/rcub_veterinar_2590 .

Marković, Lazar, Đoković, Stefan, Radaković, Milena, Francuski Andrić, Jelena, Milošević, Ivan, Beletić, Anđelo, Kovačević Filipović, Milica, "Laboratorijski profil sinovijalne tečnosti kod šest radnih konja različite starosti" in 33. Savetovanje Veterinara Srbije, Zlatibor, 08 - 11. septembra, 2022 (2022):294-300,
https://hdl.handle.net/21.15107/rcub_veterinar_2590 .

TY  - CONF
AU  - Kovandžić, Marija
AU  - Janjić, Filip
AU  - Spariosu, Kristina
AU  - Radaković, Milena
AU  - Francuski Andrić, Jelena
AU  - Beletić, Anđelo
AU  - Kovačević Filipović, Milica
PY  - 2022
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/2588
PB  - Beograd : Srpsko veterinarsko društvo
C3  - 33. Savetovanje Veterinara Srbije, Zlatibor, 08 - 11. Septembar 2022
T1  - Analiza krvne slike magaraca na velikim i malim farmama – implikacije u vezi sa eozinofilijom
IS  - 310
EP  - 311
UR  - https://hdl.handle.net/21.15107/rcub_veterinar_2588
ER  - 

@conference{
author = "Kovandžić, Marija and Janjić, Filip and Spariosu, Kristina and Radaković, Milena and Francuski Andrić, Jelena and Beletić, Anđelo and Kovačević Filipović, Milica",
year = "2022",
publisher = "Beograd : Srpsko veterinarsko društvo",
journal = "33. Savetovanje Veterinara Srbije, Zlatibor, 08 - 11. Septembar 2022",
title = "Analiza krvne slike magaraca na velikim i malim farmama – implikacije u vezi sa eozinofilijom",
number = "310",
pages = "311",
url = "https://hdl.handle.net/21.15107/rcub_veterinar_2588"
}

Kovandžić, M., Janjić, F., Spariosu, K., Radaković, M., Francuski Andrić, J., Beletić, A.,& Kovačević Filipović, M.. (2022). Analiza krvne slike magaraca na velikim i malim farmama – implikacije u vezi sa eozinofilijom. in 33. Savetovanje Veterinara Srbije, Zlatibor, 08 - 11. Septembar 2022
Beograd : Srpsko veterinarsko društvo.(310).
https://hdl.handle.net/21.15107/rcub_veterinar_2588

Kovandžić M, Janjić F, Spariosu K, Radaković M, Francuski Andrić J, Beletić A, Kovačević Filipović M. Analiza krvne slike magaraca na velikim i malim farmama – implikacije u vezi sa eozinofilijom. in 33. Savetovanje Veterinara Srbije, Zlatibor, 08 - 11. Septembar 2022. 2022;(310):null-311.
https://hdl.handle.net/21.15107/rcub_veterinar_2588 .

Kovandžić, Marija, Janjić, Filip, Spariosu, Kristina, Radaković, Milena, Francuski Andrić, Jelena, Beletić, Anđelo, Kovačević Filipović, Milica, "Analiza krvne slike magaraca na velikim i malim farmama – implikacije u vezi sa eozinofilijom" in 33. Savetovanje Veterinara Srbije, Zlatibor, 08 - 11. Septembar 2022, no. 310 (2022),
https://hdl.handle.net/21.15107/rcub_veterinar_2588 .

TY  - CONF
AU  - Janjić, Filip
AU  - Spariosu, Kristina
AU  - Kitanović, Sara
AU  - Radaković, Milena
AU  - Francuski Andrić, Jelena
AU  - Beletić, Anđelo
AU  - Kovačević Filipović, Milica
PY  - 2022
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/2586
PB  - Beograd : Srpsko veterinarsko društvo
C3  - 33. Savetovanje Veterinara Srbije, Zlatibor, 08 - 11. Septembar 2022
T1  - Retrospektivna analiza prevalence anemija i faktori rizika kod pasa i mačaka u toku 2021–2022. godine na klinici za male životinje Fakulteta Veterinarske Medicine Univerziteta u Beogradu
SP  - 312
EP  - 313
UR  - https://hdl.handle.net/21.15107/rcub_veterinar_2586
ER  - 

@conference{
author = "Janjić, Filip and Spariosu, Kristina and Kitanović, Sara and Radaković, Milena and Francuski Andrić, Jelena and Beletić, Anđelo and Kovačević Filipović, Milica",
year = "2022",
publisher = "Beograd : Srpsko veterinarsko društvo",
journal = "33. Savetovanje Veterinara Srbije, Zlatibor, 08 - 11. Septembar 2022",
title = "Retrospektivna analiza prevalence anemija i faktori rizika kod pasa i mačaka u toku 2021–2022. godine na klinici za male životinje Fakulteta Veterinarske Medicine Univerziteta u Beogradu",
pages = "312-313",
url = "https://hdl.handle.net/21.15107/rcub_veterinar_2586"
}

Janjić, F., Spariosu, K., Kitanović, S., Radaković, M., Francuski Andrić, J., Beletić, A.,& Kovačević Filipović, M.. (2022). Retrospektivna analiza prevalence anemija i faktori rizika kod pasa i mačaka u toku 2021–2022. godine na klinici za male životinje Fakulteta Veterinarske Medicine Univerziteta u Beogradu. in 33. Savetovanje Veterinara Srbije, Zlatibor, 08 - 11. Septembar 2022
Beograd : Srpsko veterinarsko društvo., 312-313.
https://hdl.handle.net/21.15107/rcub_veterinar_2586

Janjić F, Spariosu K, Kitanović S, Radaković M, Francuski Andrić J, Beletić A, Kovačević Filipović M. Retrospektivna analiza prevalence anemija i faktori rizika kod pasa i mačaka u toku 2021–2022. godine na klinici za male životinje Fakulteta Veterinarske Medicine Univerziteta u Beogradu. in 33. Savetovanje Veterinara Srbije, Zlatibor, 08 - 11. Septembar 2022. 2022;:312-313.
https://hdl.handle.net/21.15107/rcub_veterinar_2586 .

Janjić, Filip, Spariosu, Kristina, Kitanović, Sara, Radaković, Milena, Francuski Andrić, Jelena, Beletić, Anđelo, Kovačević Filipović, Milica, "Retrospektivna analiza prevalence anemija i faktori rizika kod pasa i mačaka u toku 2021–2022. godine na klinici za male životinje Fakulteta Veterinarske Medicine Univerziteta u Beogradu" in 33. Savetovanje Veterinara Srbije, Zlatibor, 08 - 11. Septembar 2022 (2022):312-313,
https://hdl.handle.net/21.15107/rcub_veterinar_2586 .

TY  - CONF
AU  - Nikolić, Milica
AU  - Radaković, Milena
AU  - Spariosu, Kristina
AU  - Kovačević Filipović, Milica
AU  - Francuski Andrić, Jelena
PY  - 2022
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/2587
PB  - Beograd : Srpsko veterinarsko društvo
C3  - 33. Savetovanje Veterinara Srbije, Zlatibor, 08 - 11. Septembar 2022
T1  - Značaj indeksa anizocitoze u dijagnostici najčešćih infektivnih anemija mačaka
SP  - 322
EP  - 323
UR  - https://hdl.handle.net/21.15107/rcub_veterinar_2587
ER  - 

@conference{
author = "Nikolić, Milica and Radaković, Milena and Spariosu, Kristina and Kovačević Filipović, Milica and Francuski Andrić, Jelena",
year = "2022",
publisher = "Beograd : Srpsko veterinarsko društvo",
journal = "33. Savetovanje Veterinara Srbije, Zlatibor, 08 - 11. Septembar 2022",
title = "Značaj indeksa anizocitoze u dijagnostici najčešćih infektivnih anemija mačaka",
pages = "322-323",
url = "https://hdl.handle.net/21.15107/rcub_veterinar_2587"
}

Nikolić, M., Radaković, M., Spariosu, K., Kovačević Filipović, M.,& Francuski Andrić, J.. (2022). Značaj indeksa anizocitoze u dijagnostici najčešćih infektivnih anemija mačaka. in 33. Savetovanje Veterinara Srbije, Zlatibor, 08 - 11. Septembar 2022
Beograd : Srpsko veterinarsko društvo., 322-323.
https://hdl.handle.net/21.15107/rcub_veterinar_2587

Nikolić M, Radaković M, Spariosu K, Kovačević Filipović M, Francuski Andrić J. Značaj indeksa anizocitoze u dijagnostici najčešćih infektivnih anemija mačaka. in 33. Savetovanje Veterinara Srbije, Zlatibor, 08 - 11. Septembar 2022. 2022;:322-323.
https://hdl.handle.net/21.15107/rcub_veterinar_2587 .

Nikolić, Milica, Radaković, Milena, Spariosu, Kristina, Kovačević Filipović, Milica, Francuski Andrić, Jelena, "Značaj indeksa anizocitoze u dijagnostici najčešćih infektivnih anemija mačaka" in 33. Savetovanje Veterinara Srbije, Zlatibor, 08 - 11. Septembar 2022 (2022):322-323,
https://hdl.handle.net/21.15107/rcub_veterinar_2587 .

TY  - CONF
AU  - Beletić, Anđelo
AU  - Kuleš, Josipa
AU  - Farkaš, Vladimir
AU  - Radaković, Milena
AU  - Rešetar Maslov, Dina
AU  - Francuski Andrić, Jelena
AU  - Spariosu, Kristina
AU  - Janjić, Filip
AU  - Rubić, Ivana
AU  - Kovačević Filipović, Milica
AU  - Mrljak, Vladimir
PY  - 2022
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/2615
C3  - 24th Annual Congress of the European Society of Veterinary Clinical Pathology, Belgrade, Serbia, October 5-8, 2022
T1  - Canine babesiosis through the eyes of proteomics and metabolomics
SP  - 72
EP  - 73
UR  - https://hdl.handle.net/21.15107/rcub_veterinar_2615
ER  - 

@conference{
author = "Beletić, Anđelo and Kuleš, Josipa and Farkaš, Vladimir and Radaković, Milena and Rešetar Maslov, Dina and Francuski Andrić, Jelena and Spariosu, Kristina and Janjić, Filip and Rubić, Ivana and Kovačević Filipović, Milica and Mrljak, Vladimir",
year = "2022",
journal = "24th Annual Congress of the European Society of Veterinary Clinical Pathology, Belgrade, Serbia, October 5-8, 2022",
title = "Canine babesiosis through the eyes of proteomics and metabolomics",
pages = "72-73",
url = "https://hdl.handle.net/21.15107/rcub_veterinar_2615"
}

Beletić, A., Kuleš, J., Farkaš, V., Radaković, M., Rešetar Maslov, D., Francuski Andrić, J., Spariosu, K., Janjić, F., Rubić, I., Kovačević Filipović, M.,& Mrljak, V.. (2022). Canine babesiosis through the eyes of proteomics and metabolomics. in 24th Annual Congress of the European Society of Veterinary Clinical Pathology, Belgrade, Serbia, October 5-8, 2022, 72-73.
https://hdl.handle.net/21.15107/rcub_veterinar_2615

Beletić A, Kuleš J, Farkaš V, Radaković M, Rešetar Maslov D, Francuski Andrić J, Spariosu K, Janjić F, Rubić I, Kovačević Filipović M, Mrljak V. Canine babesiosis through the eyes of proteomics and metabolomics. in 24th Annual Congress of the European Society of Veterinary Clinical Pathology, Belgrade, Serbia, October 5-8, 2022. 2022;:72-73.
https://hdl.handle.net/21.15107/rcub_veterinar_2615 .

Beletić, Anđelo, Kuleš, Josipa, Farkaš, Vladimir, Radaković, Milena, Rešetar Maslov, Dina, Francuski Andrić, Jelena, Spariosu, Kristina, Janjić, Filip, Rubić, Ivana, Kovačević Filipović, Milica, Mrljak, Vladimir, "Canine babesiosis through the eyes of proteomics and metabolomics" in 24th Annual Congress of the European Society of Veterinary Clinical Pathology, Belgrade, Serbia, October 5-8, 2022 (2022):72-73,
https://hdl.handle.net/21.15107/rcub_veterinar_2615 .