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The hCOMET project: International database comparison of results with the comet assay in human biomonitoring. Baseline frequency of DNA damage and effect of main confounders
(Elsevier, 2021)
The alkaline comet assay, or single cell gel electrophoresis, is one of the most popular methods for assessing DNA damage in human population. One of the open issues concerning this assay is the identification of those ...
Evaluation of cytogenetic and DNA damage in human lymphocytes treated with adrenaline in vitro
(Pergamon-Elsevier Science Ltd, Oxford, 2015)
Catechol groups can be involved in redox cycling accompanied by generation of reactive oxygen species (ROS) which may lead to oxidative damage of cellular macromolecules including DNA. The objective of this investigation ...
Nepeta rtanjensis (Lamiaceae), a plant endemic to the Balkans: Phenolic composition, antioxidant activity, and in vitro antigenotoxic effects in triiodothyronine-induced DNA damage in human lymphocytes
(Univ Karachi, Karachi, 2017)
The success of antioxidant therapy in hyperthyroidism implies that disease is mediated by oxidative stress, which is known as one of the causing agents of ageing, degenerative diseases, and cancer. The main objective of ...
Implications of oxidative stress in occupational exposure to lead on a cellular level
(Taylor & Francis Ltd, Abingdon, 2015)
The aim of this study was to determine oxidative alterations leading to cellular dysfunctions in Pb-exposed subjects by evaluating damage to all major classes of biomolecules in the cell, lipid peroxidation, protein and ...
Evaluation of the DNA damaging effects of amitraz on human lymphocytes in the Comet assay
(Indian Acad Sciences, Bangalore, 2013)
Amitraz is formamidine pesticide widely used as insecticide and acaricide. In veterinary medicine, amitraz has important uses against ticks, mites and lice on animals. Also, amitraz is used in apiculture to control Varroa ...
“Slow kill” treatment reduces DNA damage in leukocytes of dogs naturally infected with Dirofilaria immitis
(Elsevier, 2023)
Parasitic diseases are considered to be a cause of oxidative stress which leads to oxidative damage of various
molecules including DNA. This can result in mutations, replication errors, and genome instability. Therefore, ...
Oxidative stress and DNA damage in peripheral blood mononuclear cells from normal, obese, prediabetic and diabetic persons exposed to thyroid hormone in vitro
(Elsevier, 2019)
Diabetes represents one of the major health concerns, especially in developed countries. Some hormones such as
the stress hormone adrenaline can induce reactive oxygen species (ROS) and may worsen the diabetes.
Therefore, ...
Oxidative stress and DNA damage in horses naturally infected with Theileria equi
(Elsevier Sci Ltd, Oxford, 2016)
The aim of this study was to determine the concentrations of oxidative stress parameters and DNA damage in horses infected by Theileria equi. Initial screening of 110 horses with duplex PCR enabled the selection of 30 ...