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Evaluation of Thymol-β-d-Glucopyranoside as a Potential Prebiotic Intervention to Reduce Carriage of Zoonotic Pathogens in Weaned and Feeder Pigs
(MDPI, 2021)
The gut of food-producing animals is a reservoir for foodborne pathogens. Thymol is bactericidal against foodborne pathogens but rapid absorption of thymol from the proximal gut precludes the delivery of effective ...
Action of Carvacrol on Parascaris sp. and Antagonistic Effect on Nicotinic Acetylcholine Receptors
(Pharmaceuticals, 2021)
Parascaris sp. is the only ascarid parasitic nematode in equids and one of the most threatening infectious organisms in horses. Only a limited number of compounds are available for treatment of horse helminthiasis, and ...
Causes of admission, length of stay and outcomes for common kestrels in rehabilitation centres in the Czech Republic
(Nature Research, 2021)
Rehabilitation centres help injured animals to recover and return back to the wild. This study aimed to analyse trends in intake and outcomes for the common kestrels (Falco tinnunculus) admitted into rehabilitation centres ...
Prolonged continual consumption of oregano herb interferes with the action of steroid hormones and several drugs, and effects signaling across the brain-gut axis
(Royal Society of Chemistry, 2021)
Herbs and spices have been used throughout human history for their medicinal qualities. The advent of cheap and readily available medicines have lessened the need for herbs and spices as traditional medicines, however, ...
DNA-binding and DNA-protecting activities of small natural organic molecules and food extracts
(Elsevier Ireland Ltd, Clare, 2020)
The review summarizes literature data on the DNA-binding, DNA-protecting and DNA-damaging activities of a range of natural human endogenous and exogenous compounds. Small natural organic molecules bind DNA in a site-specific ...
Integration of dry-column flash chromatography with NMR and FTIR metabolomics to reveal cytotoxic metabolites from Amphoricarpos autariatus
(Elsevier, Amsterdam, 2020)
Metabolomics generate a profile of small molecules from plant extracts, which could be directly responsible for bioactivity effects. Using thy-column flash chromatography enabled a rapid and inexpensive method for the very ...
Antibacterial activity of griseofulvin analogues as an example of drug repurposing
(Elsevier, 2020)
Griseofulvin is a well-known antifungal drug that was launched in 1962 by Merck & Co. for the treatment of dermatophyte infections. However, according to predictions using the Way2Drug computational drug repurposing platform, ...