TY  - CONF
AU  - Nedeljković-Trailović, Jelena
AU  - Jovanović, Dragoljub
AU  - Petrujkić, Branko
PY  - 2024
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/3716
AB  - Problem otpada je rastući problem u svetu. Većina svetskih propisa
ograničava mogućnost deponovanja otpada i bezbedno upravljanje
otpadom preusmerava na insineratore tj. spalionice otpada. Verovanje
da će spaljivanjem otpad nestati, dovelo je do masovne insineracije
kao široko rasprostranjene metode “odlaganja” svih vrsta otpada,
uključujući i opasan otpad kakav je medicinski i hemijski. Insineracijom
se smanjuje zapremina otpada, uništavaju se bakterije i virusi.
Nažalost, spaljivanje nije “čist“ proces i pored emisije gasova dolazi
do stvaranja velike količine pepela čije čestice na sebi nose veoma
toksične polutante kao što su polihlorovani dibenzo dioksini (PCDDi),
polihlorovani dibenzo furani (PCDFi). Radi se o nepolarnim, lipofilnim
jedinjenjima koja se lako akumuliraju u životnoj sredini, veoma su postojani
zbog čega predstavljaju opasnost po zdravlje ljudi. Osim u procesu
insineracije mogu nastati i u toku velikih šumskih požara ili u toku
nekih industrijskih procesa kao što je proizvodnja pesticida. U lanac
ishrane životinja dospevaju putem kontaminarane hrane tj. zemljišta i
biljaka koje ih bioakumuliraju. U lanac hrane ljudi dospevaju preko namirnica
animalnog porekla kao što su jaja, meso i životinjske masti.
Zbog velikog toksičnog i karcinogenog potencijala propisan je čitav
niz mera kontrole prisustva ovih veoma toksičnih jedinjenja u životnoj
sredini kao i hrani za ljude i životinje.
PB  - Beograd : Fakultet veterinarske medicine, Centar za izdavačku delatnost i promet učila
C3  - XLV seminar za inovacije znanja veterinara, Beograd, 23. februar 2024
T1  - Pojava dioksina, furana i polihlorovanih bifenila u hrani za životinje kao posledica narušenih ekoloških principa
SP  - 69
EP  - 81
UR  - https://hdl.handle.net/21.15107/rcub_veterinar_3716
ER  - 

@conference{
author = "Nedeljković-Trailović, Jelena and Jovanović, Dragoljub and Petrujkić, Branko",
year = "2024",
abstract = "Problem otpada je rastući problem u svetu. Većina svetskih propisa
ograničava mogućnost deponovanja otpada i bezbedno upravljanje
otpadom preusmerava na insineratore tj. spalionice otpada. Verovanje
da će spaljivanjem otpad nestati, dovelo je do masovne insineracije
kao široko rasprostranjene metode “odlaganja” svih vrsta otpada,
uključujući i opasan otpad kakav je medicinski i hemijski. Insineracijom
se smanjuje zapremina otpada, uništavaju se bakterije i virusi.
Nažalost, spaljivanje nije “čist“ proces i pored emisije gasova dolazi
do stvaranja velike količine pepela čije čestice na sebi nose veoma
toksične polutante kao što su polihlorovani dibenzo dioksini (PCDDi),
polihlorovani dibenzo furani (PCDFi). Radi se o nepolarnim, lipofilnim
jedinjenjima koja se lako akumuliraju u životnoj sredini, veoma su postojani
zbog čega predstavljaju opasnost po zdravlje ljudi. Osim u procesu
insineracije mogu nastati i u toku velikih šumskih požara ili u toku
nekih industrijskih procesa kao što je proizvodnja pesticida. U lanac
ishrane životinja dospevaju putem kontaminarane hrane tj. zemljišta i
biljaka koje ih bioakumuliraju. U lanac hrane ljudi dospevaju preko namirnica
animalnog porekla kao što su jaja, meso i životinjske masti.
Zbog velikog toksičnog i karcinogenog potencijala propisan je čitav
niz mera kontrole prisustva ovih veoma toksičnih jedinjenja u životnoj
sredini kao i hrani za ljude i životinje.",
publisher = "Beograd : Fakultet veterinarske medicine, Centar za izdavačku delatnost i promet učila",
journal = "XLV seminar za inovacije znanja veterinara, Beograd, 23. februar 2024",
title = "Pojava dioksina, furana i polihlorovanih bifenila u hrani za životinje kao posledica narušenih ekoloških principa",
pages = "69-81",
url = "https://hdl.handle.net/21.15107/rcub_veterinar_3716"
}

Nedeljković-Trailović, J., Jovanović, D.,& Petrujkić, B.. (2024). Pojava dioksina, furana i polihlorovanih bifenila u hrani za životinje kao posledica narušenih ekoloških principa. in XLV seminar za inovacije znanja veterinara, Beograd, 23. februar 2024
Beograd : Fakultet veterinarske medicine, Centar za izdavačku delatnost i promet učila., 69-81.
https://hdl.handle.net/21.15107/rcub_veterinar_3716

Nedeljković-Trailović J, Jovanović D, Petrujkić B. Pojava dioksina, furana i polihlorovanih bifenila u hrani za životinje kao posledica narušenih ekoloških principa. in XLV seminar za inovacije znanja veterinara, Beograd, 23. februar 2024. 2024;:69-81.
https://hdl.handle.net/21.15107/rcub_veterinar_3716 .

Nedeljković-Trailović, Jelena, Jovanović, Dragoljub, Petrujkić, Branko, "Pojava dioksina, furana i polihlorovanih bifenila u hrani za životinje kao posledica narušenih ekoloških principa" in XLV seminar za inovacije znanja veterinara, Beograd, 23. februar 2024 (2024):69-81,
https://hdl.handle.net/21.15107/rcub_veterinar_3716 .

TY  - JOUR
AU  - Stojković, Maja
AU  - Todorović, Zoran
AU  - Protić, Dragana
AU  - Stevanović, Strahinja
AU  - Medić, Dragana
AU  - Charvet, Claude L.
AU  - Marjanović, Djordje
AU  - Nedeljković Trailović, Jelena
AU  - Trailović, Saša M.
PY  - 2024
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/3564
AB  - The control of parasitic nematode infections relies mostly on anthelmintics. The potential pharmacotherapeutic application of phytochemicals, in order to overcome parasite resistance and enhance the effect of existing drugs, is becoming increasingly important. The antinematodal effects of carveol was tested on the free-living nematode Caenorhabditis elegans and the neuromuscular preparation of the parasitic nematode Ascaris suum. Carveol caused spastic and geraniol atonic paralysis in C. elegans. In A. suum carveol potentiated contractions induced by acetylcholine (ACh) and this effect was confirmed with two-electrode voltage-clamp electrophysiology on the A. suum nicotinic acetylcholine receptor expressed in Xenopus oocytes. However, potentiating effect of carveol on ACh-induced contractions was partially sensitive to atropine, indicates a dominant nicotine effect but also the involvement of some muscarinic structures. The effects of carveol on the neuromuscular system of mammals are also specific. In micromolar concentrations, carveol acts as a non-competitive ACh antagonist on ileum contractions. Unlike atropine, it does not change the EC50 of ACh but reduces the amplitude of contractions. Carveol caused an increase in Electrical Field Stimulation-evoked contractions of the isolated rat diaphragm, but at higher concentrations it caused an inhibition. Also, carveol neutralized the mecamylamine-induced tetanic fade, indicating a possibly different pre-and post-synaptic action at the neuromuscular junction.
PB  - Frontiers Media
T2  - Frontiers in Pharmacology
T1  - Pharmacological effects of monoterpene carveol on the neuromuscular system of nematodes and mammals
VL  - 15
DO  - 10.3389/fphar.2024.1326779
ER  - 

@article{
author = "Stojković, Maja and Todorović, Zoran and Protić, Dragana and Stevanović, Strahinja and Medić, Dragana and Charvet, Claude L. and Marjanović, Djordje and Nedeljković Trailović, Jelena and Trailović, Saša M.",
year = "2024",
abstract = "The control of parasitic nematode infections relies mostly on anthelmintics. The potential pharmacotherapeutic application of phytochemicals, in order to overcome parasite resistance and enhance the effect of existing drugs, is becoming increasingly important. The antinematodal effects of carveol was tested on the free-living nematode Caenorhabditis elegans and the neuromuscular preparation of the parasitic nematode Ascaris suum. Carveol caused spastic and geraniol atonic paralysis in C. elegans. In A. suum carveol potentiated contractions induced by acetylcholine (ACh) and this effect was confirmed with two-electrode voltage-clamp electrophysiology on the A. suum nicotinic acetylcholine receptor expressed in Xenopus oocytes. However, potentiating effect of carveol on ACh-induced contractions was partially sensitive to atropine, indicates a dominant nicotine effect but also the involvement of some muscarinic structures. The effects of carveol on the neuromuscular system of mammals are also specific. In micromolar concentrations, carveol acts as a non-competitive ACh antagonist on ileum contractions. Unlike atropine, it does not change the EC50 of ACh but reduces the amplitude of contractions. Carveol caused an increase in Electrical Field Stimulation-evoked contractions of the isolated rat diaphragm, but at higher concentrations it caused an inhibition. Also, carveol neutralized the mecamylamine-induced tetanic fade, indicating a possibly different pre-and post-synaptic action at the neuromuscular junction.",
publisher = "Frontiers Media",
journal = "Frontiers in Pharmacology",
title = "Pharmacological effects of monoterpene carveol on the neuromuscular system of nematodes and mammals",
volume = "15",
doi = "10.3389/fphar.2024.1326779"
}

Stojković, M., Todorović, Z., Protić, D., Stevanović, S., Medić, D., Charvet, C. L., Marjanović, D., Nedeljković Trailović, J.,& Trailović, S. M.. (2024). Pharmacological effects of monoterpene carveol on the neuromuscular system of nematodes and mammals. in Frontiers in Pharmacology
Frontiers Media., 15.
https://doi.org/10.3389/fphar.2024.1326779

Stojković M, Todorović Z, Protić D, Stevanović S, Medić D, Charvet CL, Marjanović D, Nedeljković Trailović J, Trailović SM. Pharmacological effects of monoterpene carveol on the neuromuscular system of nematodes and mammals. in Frontiers in Pharmacology. 2024;15.
doi:10.3389/fphar.2024.1326779 .

Stojković, Maja, Todorović, Zoran, Protić, Dragana, Stevanović, Strahinja, Medić, Dragana, Charvet, Claude L., Marjanović, Djordje, Nedeljković Trailović, Jelena, Trailović, Saša M., "Pharmacological effects of monoterpene carveol on the neuromuscular system of nematodes and mammals" in Frontiers in Pharmacology, 15 (2024),
https://doi.org/10.3389/fphar.2024.1326779 . .

TY  - JOUR
AU  - Stefanović, Darko
AU  - Marinković, Darko
AU  - Trailović, Saša
AU  - Vasiljević, Marko
AU  - Farkaš, Hunor
AU  - Raj, Jog
AU  - Tolimir, Nataša
AU  - Radulović, Stamen
AU  - Nešić, Vladimir
AU  - Nedeljković-Trailović, Jelena
AU  - Petrujkić, Branko
PY  - 2023
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/2629
AB  - This experimental study was conducted to determine the ability of a novel mycotoxins detoxification agent (MR) at a concentration of 0.2% to reduce the toxicity of aflatoxin B1 (AFB1) or T-2 toxin, alone or in combination, and to examine its effect on performance, pathohistological changes (PH) and the residue of these toxins in the tissues of broiler chicks. A total of 96 broiler chicks were divided into eight equal groups: group C, which served as control (without any additives); group MR, which received the novel detoxification agent (supplemented with 0.2%); group E-I (0.1 mg AFB1/kg of diet); group E-II (0.1 mg AFB1/kg of diet + MR 0.2%); group E-III (0.5 mg T-2 toxin/kg of diet); group E-IV (0.5 mg T-2 toxin/kg of diet + 0.2% MR); group E-V (combination of 0.1 mg AFB1/kg, 0.5 mg T-2 toxin/kg of diet); and group E-VI (combination of 0.1 mg AFB1/kg, 0.5 mg T-2 toxin + 0.2% MR). Results indicate that feeds containing AFB1 and T-2 toxin, alone or in combination, adversely affected the health and performance of poultry. However, the addition of MR to diets containing AFB1 and T-2 toxin singly and in combination exerted a positive effect on body weight, feed intake, weight gain, feed efficiency and microscopic lesions in visceral organs. Residual concentration of AFB1 in liver samples was significantly (p < 0.05) decreased when chicks were fed diets supplemented with 0.2% of MR.
PB  - MDPI
T2  - Microorganisms
T1  - Evaluation of Effectiveness of a Novel Multicomponent Mycotoxins Detoxification Agent in the Presence of AFB1 and T-2 Toxin on Broiler Chicks
VL  - 11
IS  - 3
SP  - 574
DO  - 10.3390/microorganisms11030574
ER  - 

@article{
author = "Stefanović, Darko and Marinković, Darko and Trailović, Saša and Vasiljević, Marko and Farkaš, Hunor and Raj, Jog and Tolimir, Nataša and Radulović, Stamen and Nešić, Vladimir and Nedeljković-Trailović, Jelena and Petrujkić, Branko",
year = "2023",
abstract = "This experimental study was conducted to determine the ability of a novel mycotoxins detoxification agent (MR) at a concentration of 0.2% to reduce the toxicity of aflatoxin B1 (AFB1) or T-2 toxin, alone or in combination, and to examine its effect on performance, pathohistological changes (PH) and the residue of these toxins in the tissues of broiler chicks. A total of 96 broiler chicks were divided into eight equal groups: group C, which served as control (without any additives); group MR, which received the novel detoxification agent (supplemented with 0.2%); group E-I (0.1 mg AFB1/kg of diet); group E-II (0.1 mg AFB1/kg of diet + MR 0.2%); group E-III (0.5 mg T-2 toxin/kg of diet); group E-IV (0.5 mg T-2 toxin/kg of diet + 0.2% MR); group E-V (combination of 0.1 mg AFB1/kg, 0.5 mg T-2 toxin/kg of diet); and group E-VI (combination of 0.1 mg AFB1/kg, 0.5 mg T-2 toxin + 0.2% MR). Results indicate that feeds containing AFB1 and T-2 toxin, alone or in combination, adversely affected the health and performance of poultry. However, the addition of MR to diets containing AFB1 and T-2 toxin singly and in combination exerted a positive effect on body weight, feed intake, weight gain, feed efficiency and microscopic lesions in visceral organs. Residual concentration of AFB1 in liver samples was significantly (p < 0.05) decreased when chicks were fed diets supplemented with 0.2% of MR.",
publisher = "MDPI",
journal = "Microorganisms",
title = "Evaluation of Effectiveness of a Novel Multicomponent Mycotoxins Detoxification Agent in the Presence of AFB1 and T-2 Toxin on Broiler Chicks",
volume = "11",
number = "3",
pages = "574",
doi = "10.3390/microorganisms11030574"
}

Stefanović, D., Marinković, D., Trailović, S., Vasiljević, M., Farkaš, H., Raj, J., Tolimir, N., Radulović, S., Nešić, V., Nedeljković-Trailović, J.,& Petrujkić, B.. (2023). Evaluation of Effectiveness of a Novel Multicomponent Mycotoxins Detoxification Agent in the Presence of AFB1 and T-2 Toxin on Broiler Chicks. in Microorganisms
MDPI., 11(3), 574.
https://doi.org/10.3390/microorganisms11030574

Stefanović D, Marinković D, Trailović S, Vasiljević M, Farkaš H, Raj J, Tolimir N, Radulović S, Nešić V, Nedeljković-Trailović J, Petrujkić B. Evaluation of Effectiveness of a Novel Multicomponent Mycotoxins Detoxification Agent in the Presence of AFB1 and T-2 Toxin on Broiler Chicks. in Microorganisms. 2023;11(3):574.
doi:10.3390/microorganisms11030574 .

Stefanović, Darko, Marinković, Darko, Trailović, Saša, Vasiljević, Marko, Farkaš, Hunor, Raj, Jog, Tolimir, Nataša, Radulović, Stamen, Nešić, Vladimir, Nedeljković-Trailović, Jelena, Petrujkić, Branko, "Evaluation of Effectiveness of a Novel Multicomponent Mycotoxins Detoxification Agent in the Presence of AFB1 and T-2 Toxin on Broiler Chicks" in Microorganisms, 11, no. 3 (2023):574,
https://doi.org/10.3390/microorganisms11030574 . .

TY  - CONF
AU  - Petrujkić, Branko
AU  - Radulović, Stamen
AU  - Nedeljković-Trailović, Jelena
PY  - 2023
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/3228
AB  - Tokom poslednjih 40 godina, upotreba dopunskih masti i ulja u obrocima visokomlečnih
krava postala je standardna praksa. Masti se dodaju sa ciljem povećanja
energetske gustine obroka. Povećani unos energije trebalo bi da poboljša energetsku
ravnotežu, kondiciju, poveća proizvodnju mleka, poboljša reprodukciju i poveća
sadržaj mlečne masti. Mlečne krave konzumiraju hranu koja pretežno sadrži
polinezasićene masti (PUFA) kao deo biljnih triglicerida i glikolipida. Nezasićene
masne kiseline su toksične bakterije buraga, posebno one koje su uključene u varenje
celuloze. Negativni efekti nezasićenih masti na m.o. koji vare vlakna su glavni razlog
zašto se velike količine „slobodnih“ biljnih ulja ne mogu davati mlečnim kravama. U
mlečnoj masti krava, palmitinska kiselina (16:0) je najčešća masna kiselina, ujedno je
i najzastupljenija masna kiselina u palminom ulju, po kojoj i dobija ime.
Raznovrsni dodaci masti danas su dostupni za mlečne krave. Tzv „inertne masti“ imaju
manji uticaj na fermentaciju buraga nego klasične masti, druga velika prednost
komercijalnih masti je ta što su to „suve“ masti kojima se može lakše rukovati. Postoje
tri glavne strategije za proizvodnju inertnih masti. Prva je povećanje zasićenosti
masnih kiselina tako da tačka topljenja bude iznad opsega temperature okoline, ovo
smanjuje rastvorljivost i potencijalnu interakciju masti sa m.o. buraga. Druga
strategija je vezivanje masne kiseline sa kalcijumom da bi se formirali kalcijumovi
sapuni. Budući da je slobodna masna kiselina potrebna za biohidrogenizaciju i
interakciju sa m.o., vezivanje masnih kiselina u sapun sprečava ovu interakciju.
Konačno, masti mogu biti „inkapsulirane“ na različite načine kako bi se fizički sprečila
interakcija sa m.o. buraga. Od pomenutih strategija, samo prve dve su trenutno u
komercijalnoj upotrebi. Podaci iz brojnih istraživačkih studija ukazuju na malu razliku
u svarljivosti između prve dve vrste inertnih masti, sa malom prednošću za
kalcijumove sapune.
PB  - Beograd : Srpsko veterinarsko društvo
C3  - 34. Savetovanje veterinara Srbije, Zlatibor, 07 - 10. septembar 2023
T1  - Dodavanje masti obrocima visoko mlečnih krava - Trenutni trend ili potreba
SP  - 155
EP  - 163
UR  - https://hdl.handle.net/21.15107/rcub_veterinar_3228
ER  - 

@conference{
author = "Petrujkić, Branko and Radulović, Stamen and Nedeljković-Trailović, Jelena",
year = "2023",
abstract = "Tokom poslednjih 40 godina, upotreba dopunskih masti i ulja u obrocima visokomlečnih
krava postala je standardna praksa. Masti se dodaju sa ciljem povećanja
energetske gustine obroka. Povećani unos energije trebalo bi da poboljša energetsku
ravnotežu, kondiciju, poveća proizvodnju mleka, poboljša reprodukciju i poveća
sadržaj mlečne masti. Mlečne krave konzumiraju hranu koja pretežno sadrži
polinezasićene masti (PUFA) kao deo biljnih triglicerida i glikolipida. Nezasićene
masne kiseline su toksične bakterije buraga, posebno one koje su uključene u varenje
celuloze. Negativni efekti nezasićenih masti na m.o. koji vare vlakna su glavni razlog
zašto se velike količine „slobodnih“ biljnih ulja ne mogu davati mlečnim kravama. U
mlečnoj masti krava, palmitinska kiselina (16:0) je najčešća masna kiselina, ujedno je
i najzastupljenija masna kiselina u palminom ulju, po kojoj i dobija ime.
Raznovrsni dodaci masti danas su dostupni za mlečne krave. Tzv „inertne masti“ imaju
manji uticaj na fermentaciju buraga nego klasične masti, druga velika prednost
komercijalnih masti je ta što su to „suve“ masti kojima se može lakše rukovati. Postoje
tri glavne strategije za proizvodnju inertnih masti. Prva je povećanje zasićenosti
masnih kiselina tako da tačka topljenja bude iznad opsega temperature okoline, ovo
smanjuje rastvorljivost i potencijalnu interakciju masti sa m.o. buraga. Druga
strategija je vezivanje masne kiseline sa kalcijumom da bi se formirali kalcijumovi
sapuni. Budući da je slobodna masna kiselina potrebna za biohidrogenizaciju i
interakciju sa m.o., vezivanje masnih kiselina u sapun sprečava ovu interakciju.
Konačno, masti mogu biti „inkapsulirane“ na različite načine kako bi se fizički sprečila
interakcija sa m.o. buraga. Od pomenutih strategija, samo prve dve su trenutno u
komercijalnoj upotrebi. Podaci iz brojnih istraživačkih studija ukazuju na malu razliku
u svarljivosti između prve dve vrste inertnih masti, sa malom prednošću za
kalcijumove sapune.",
publisher = "Beograd : Srpsko veterinarsko društvo",
journal = "34. Savetovanje veterinara Srbije, Zlatibor, 07 - 10. septembar 2023",
title = "Dodavanje masti obrocima visoko mlečnih krava - Trenutni trend ili potreba",
pages = "155-163",
url = "https://hdl.handle.net/21.15107/rcub_veterinar_3228"
}

Petrujkić, B., Radulović, S.,& Nedeljković-Trailović, J.. (2023). Dodavanje masti obrocima visoko mlečnih krava - Trenutni trend ili potreba. in 34. Savetovanje veterinara Srbije, Zlatibor, 07 - 10. septembar 2023
Beograd : Srpsko veterinarsko društvo., 155-163.
https://hdl.handle.net/21.15107/rcub_veterinar_3228

Petrujkić B, Radulović S, Nedeljković-Trailović J. Dodavanje masti obrocima visoko mlečnih krava - Trenutni trend ili potreba. in 34. Savetovanje veterinara Srbije, Zlatibor, 07 - 10. septembar 2023. 2023;:155-163.
https://hdl.handle.net/21.15107/rcub_veterinar_3228 .

Petrujkić, Branko, Radulović, Stamen, Nedeljković-Trailović, Jelena, "Dodavanje masti obrocima visoko mlečnih krava - Trenutni trend ili potreba" in 34. Savetovanje veterinara Srbije, Zlatibor, 07 - 10. septembar 2023 (2023):155-163,
https://hdl.handle.net/21.15107/rcub_veterinar_3228 .

TY  - JOUR
AU  - Vasiljević, Marko
AU  - Milićević, Dragan
AU  - Pleadin, Jelka
AU  - Tolmir, Nataša
AU  - Trailović, Saša
AU  - Resanović, Radmila
AU  - Nedeljković-Trailović, Jelena
PY  - 2022
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/2627
AB  - The objective of this study was to evaluate the efficacy of modified clinoptilolite as mycotoxins adsorbent in preventing negative effects of ochratoxin A (OTA) on egg production and egg quality of laying hens exposed to this mycotoxin. Forty-eight (n=48) laying hens (27 weeks old) were used in this study. The hens were randomly divided into six equal groups and were fed for 7 weeks with a standard diet in addition to: E-I group - 1 mg/kg OTA; E-II group 0.25 mg/kg OTA; E-III group 1mg/kg OTA + 0.2% of MZ; E-IV group 0.25 mg/kg OTA + 0.2% of MZ. MZ group of hens was fed with standard diets containing 0.2% of the adsorbent (MZ). The control group of hens was fed with standard diet, without any addition of OTA or MZ. The present study showed that laying hens fed with 1 mg/kg of OTA (E-I), had a significant decrease (p<0.05) of all performance parameters during the trial, while group fed with 0.25 mg/kg OTA have shown no adverse effects on egg production and egg quality. Addition of modified clinoptilolite (0.2%) to the diet containing the OTA, minimized these effects bringing values not significantly different from the control diet for most of the parameters. These findings clearly indicate the protective potential of modified clinoptilolite against the toxic effects of OTA in laying hens.
PB  - Foundation of Poultry Science and Technology - FACTA.
T2  - Brazilian Journal of Poultry Science
T1  - Effect of Modified Clinoptilolite to Counteract the Deleterious Effects of Ochratoxin A on Egg Production and Quality
VL  - 24
IS  - 3
DO  - 10.1590/1806-9061-2021-1495
ER  - 

@article{
author = "Vasiljević, Marko and Milićević, Dragan and Pleadin, Jelka and Tolmir, Nataša and Trailović, Saša and Resanović, Radmila and Nedeljković-Trailović, Jelena",
year = "2022",
abstract = "The objective of this study was to evaluate the efficacy of modified clinoptilolite as mycotoxins adsorbent in preventing negative effects of ochratoxin A (OTA) on egg production and egg quality of laying hens exposed to this mycotoxin. Forty-eight (n=48) laying hens (27 weeks old) were used in this study. The hens were randomly divided into six equal groups and were fed for 7 weeks with a standard diet in addition to: E-I group - 1 mg/kg OTA; E-II group 0.25 mg/kg OTA; E-III group 1mg/kg OTA + 0.2% of MZ; E-IV group 0.25 mg/kg OTA + 0.2% of MZ. MZ group of hens was fed with standard diets containing 0.2% of the adsorbent (MZ). The control group of hens was fed with standard diet, without any addition of OTA or MZ. The present study showed that laying hens fed with 1 mg/kg of OTA (E-I), had a significant decrease (p<0.05) of all performance parameters during the trial, while group fed with 0.25 mg/kg OTA have shown no adverse effects on egg production and egg quality. Addition of modified clinoptilolite (0.2%) to the diet containing the OTA, minimized these effects bringing values not significantly different from the control diet for most of the parameters. These findings clearly indicate the protective potential of modified clinoptilolite against the toxic effects of OTA in laying hens.",
publisher = "Foundation of Poultry Science and Technology - FACTA.",
journal = "Brazilian Journal of Poultry Science",
title = "Effect of Modified Clinoptilolite to Counteract the Deleterious Effects of Ochratoxin A on Egg Production and Quality",
volume = "24",
number = "3",
doi = "10.1590/1806-9061-2021-1495"
}

Vasiljević, M., Milićević, D., Pleadin, J., Tolmir, N., Trailović, S., Resanović, R.,& Nedeljković-Trailović, J.. (2022). Effect of Modified Clinoptilolite to Counteract the Deleterious Effects of Ochratoxin A on Egg Production and Quality. in Brazilian Journal of Poultry Science
Foundation of Poultry Science and Technology - FACTA.., 24(3).
https://doi.org/10.1590/1806-9061-2021-1495

Vasiljević M, Milićević D, Pleadin J, Tolmir N, Trailović S, Resanović R, Nedeljković-Trailović J. Effect of Modified Clinoptilolite to Counteract the Deleterious Effects of Ochratoxin A on Egg Production and Quality. in Brazilian Journal of Poultry Science. 2022;24(3).
doi:10.1590/1806-9061-2021-1495 .

Vasiljević, Marko, Milićević, Dragan, Pleadin, Jelka, Tolmir, Nataša, Trailović, Saša, Resanović, Radmila, Nedeljković-Trailović, Jelena, "Effect of Modified Clinoptilolite to Counteract the Deleterious Effects of Ochratoxin A on Egg Production and Quality" in Brazilian Journal of Poultry Science, 24, no. 3 (2022),
https://doi.org/10.1590/1806-9061-2021-1495 . .

TY  - JOUR
AU  - Mijatović, Bojana
AU  - Pavlović, Ivan
AU  - Živković, Slavica
AU  - Trailović, Ivana
AU  - Ćirić, Jelena
AU  - Trailović, Dragiša
PY  - 2022
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/3401
AB  - The Balkan donkey, Equus asinus, is an endangered indigenous breed that was once found in the wider area of
the Balkan Peninsula, especially in the hilly and mountainous areas of Serbia. It is estimated that today there are about 1,000
of them left, mostly in animal genetic resources breeding centers. They are characterized by exceptional resistance to disease
and, to date, have not been subject to disease prevention measures, including parasite control. Herein, we examined parasite
species richness and prevalence of endoparasites in 60 adult donkeys of both sexes from 3 sites: Stara planina Nature Park (a
mountainous region corresponding to the original habitat where this species was once bred); Zasavica Special Nature Reserve
(a plain area at the mouth of the Zasavica in the Sava River), and Krˇcedinska ada (a marsh island on the Danube River near
Novi Sad). We found the most prevalent parasites were Dictyocaulus arnfieldi (68% at Stara planina and 100% at the other 2
sites); Trichostrongylus axei (38% at Stara planina, 57% at Zasavica, and 86% at Krˇcedinska ada); Strongylus vulgaris (32%
at Stara planina and 435% at Krˇcedinska ada); and Strongylus edentatus (57% at Zasavica and 14% at Krˇcedinska ada). In
addition, we found Cyathostomum spp., Anoplocephala spp., Eimeria leuckarti, and Eimeria solipedum in smaller numbers.
PB  - The Helminthological Society of Washington
T2  - Comparative Parasitology
T1  - Prevalence of Endoparasites in the Balkan Donkey (Equus asinus) from Serbia
VL  - 89
IS  - 2
SP  - 115
EP  - 121
DO  - 10.1654/COPA-D-22-00005
ER  - 

@article{
author = "Mijatović, Bojana and Pavlović, Ivan and Živković, Slavica and Trailović, Ivana and Ćirić, Jelena and Trailović, Dragiša",
year = "2022",
abstract = "The Balkan donkey, Equus asinus, is an endangered indigenous breed that was once found in the wider area of
the Balkan Peninsula, especially in the hilly and mountainous areas of Serbia. It is estimated that today there are about 1,000
of them left, mostly in animal genetic resources breeding centers. They are characterized by exceptional resistance to disease
and, to date, have not been subject to disease prevention measures, including parasite control. Herein, we examined parasite
species richness and prevalence of endoparasites in 60 adult donkeys of both sexes from 3 sites: Stara planina Nature Park (a
mountainous region corresponding to the original habitat where this species was once bred); Zasavica Special Nature Reserve
(a plain area at the mouth of the Zasavica in the Sava River), and Krˇcedinska ada (a marsh island on the Danube River near
Novi Sad). We found the most prevalent parasites were Dictyocaulus arnfieldi (68% at Stara planina and 100% at the other 2
sites); Trichostrongylus axei (38% at Stara planina, 57% at Zasavica, and 86% at Krˇcedinska ada); Strongylus vulgaris (32%
at Stara planina and 435% at Krˇcedinska ada); and Strongylus edentatus (57% at Zasavica and 14% at Krˇcedinska ada). In
addition, we found Cyathostomum spp., Anoplocephala spp., Eimeria leuckarti, and Eimeria solipedum in smaller numbers.",
publisher = "The Helminthological Society of Washington",
journal = "Comparative Parasitology",
title = "Prevalence of Endoparasites in the Balkan Donkey (Equus asinus) from Serbia",
volume = "89",
number = "2",
pages = "115-121",
doi = "10.1654/COPA-D-22-00005"
}

Mijatović, B., Pavlović, I., Živković, S., Trailović, I., Ćirić, J.,& Trailović, D.. (2022). Prevalence of Endoparasites in the Balkan Donkey (Equus asinus) from Serbia. in Comparative Parasitology
The Helminthological Society of Washington., 89(2), 115-121.
https://doi.org/10.1654/COPA-D-22-00005

Mijatović B, Pavlović I, Živković S, Trailović I, Ćirić J, Trailović D. Prevalence of Endoparasites in the Balkan Donkey (Equus asinus) from Serbia. in Comparative Parasitology. 2022;89(2):115-121.
doi:10.1654/COPA-D-22-00005 .

Mijatović, Bojana, Pavlović, Ivan, Živković, Slavica, Trailović, Ivana, Ćirić, Jelena, Trailović, Dragiša, "Prevalence of Endoparasites in the Balkan Donkey (Equus asinus) from Serbia" in Comparative Parasitology, 89, no. 2 (2022):115-121,
https://doi.org/10.1654/COPA-D-22-00005 . .

TY  - JOUR
AU  - Marjanović, Đorđe
AU  - Zdravković, Nemanja
AU  - Milovanović, Mirjana
AU  - Nedeljković-Trailović, Jelena
AU  - Robertson, Alan P.
AU  - Todorović, Zoran
AU  - Trailović, Saša
PY  - 2020
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/1807
AB  - The neuromuscular system of parasitic nematodes has proven to be an efficient pharmacological target for antihelmintics. Some of the most frequently used antiparasitic drugs are agonists or antagonists of nicotinic acetylcholine receptors (nAChRs). The antinematodal mechanism of action of carvacrol involves the inhibition of parasite muscle contraction. We have examined the interaction of carvacrol with antinematodal drugs that are agonists of different subtypes of nAChRs and monepantel, which is a non-competitive antagonist of this receptor in A. suum. Additionally, we investigated the effect of carvacrol on the muscle type of nAChRs in the mammalian host. As orthosteric agonists of nAChR, pyrantel, morantel and befinijum lead to dose-dependent contractions of the neuromuscular preparation of Ascaris suum. Carvacrol 100 mu M decreased the E-max of pyrantel, morantel and bephenium by 29%, 39% and 12 %, 39 % and 12 % respectively. The EC50 ratio was 3.43, 2.95 and 2.47 for pyrantel, morantel and bephinium, respectively. Carvacrol 300 u mu M reduces the E-max of pyrantel, morantel and bephenium by 71%, 80% and 75 %, 80 % and 75 % respectively. The EC50 ratio for pyrantel, morantel and bephenium was 3.88, 3.19 and 4.83 respectively. Furthermore, carvacrol enhances the inhibitory effect of monepantel on A. mum contractions, which may have an effective clinical application. On the other hand, tested concentrations of carvacrol did not significantly affect the EFS-induced contractions of the rat diaphragm, indicating a lack of interaction with the postsynaptic nAChR at the muscle end plate in mammals, but the highest concentration (300 mu M) caused a clear tetanic fade. Carvacrol exhibited a time and dose-dependent effect on the Rota-rod performances of rats with a high value of the ED50 (421.6 mg/kg). In our research, carvacrol dominantly exhibited characteristics of a non-competitive antagonist of nAChR in A. suum, and enhances the inhibitory effect of monepantel. The combination of monepantel and carvacrol may be clinically very effective, and the carvacrol molecule itself can be used as a promising platform for the development of new anthelmintic drugs.
PB  - Elsevier, Amsterdam
T2  - Veterinary Parasitology
T1  - Carvacrol acts as a potent selective antagonist of different types of nicotinic acetylcholine receptors and enhances the effect of monepantel in the parasitic nematode Ascaris suum
VL  - 278
SP  - UNSP 109031
DO  - 10.1016/j.vetpar.2020.109031
ER  - 

@article{
author = "Marjanović, Đorđe and Zdravković, Nemanja and Milovanović, Mirjana and Nedeljković-Trailović, Jelena and Robertson, Alan P. and Todorović, Zoran and Trailović, Saša",
year = "2020",
abstract = "The neuromuscular system of parasitic nematodes has proven to be an efficient pharmacological target for antihelmintics. Some of the most frequently used antiparasitic drugs are agonists or antagonists of nicotinic acetylcholine receptors (nAChRs). The antinematodal mechanism of action of carvacrol involves the inhibition of parasite muscle contraction. We have examined the interaction of carvacrol with antinematodal drugs that are agonists of different subtypes of nAChRs and monepantel, which is a non-competitive antagonist of this receptor in A. suum. Additionally, we investigated the effect of carvacrol on the muscle type of nAChRs in the mammalian host. As orthosteric agonists of nAChR, pyrantel, morantel and befinijum lead to dose-dependent contractions of the neuromuscular preparation of Ascaris suum. Carvacrol 100 mu M decreased the E-max of pyrantel, morantel and bephenium by 29%, 39% and 12 %, 39 % and 12 % respectively. The EC50 ratio was 3.43, 2.95 and 2.47 for pyrantel, morantel and bephinium, respectively. Carvacrol 300 u mu M reduces the E-max of pyrantel, morantel and bephenium by 71%, 80% and 75 %, 80 % and 75 % respectively. The EC50 ratio for pyrantel, morantel and bephenium was 3.88, 3.19 and 4.83 respectively. Furthermore, carvacrol enhances the inhibitory effect of monepantel on A. mum contractions, which may have an effective clinical application. On the other hand, tested concentrations of carvacrol did not significantly affect the EFS-induced contractions of the rat diaphragm, indicating a lack of interaction with the postsynaptic nAChR at the muscle end plate in mammals, but the highest concentration (300 mu M) caused a clear tetanic fade. Carvacrol exhibited a time and dose-dependent effect on the Rota-rod performances of rats with a high value of the ED50 (421.6 mg/kg). In our research, carvacrol dominantly exhibited characteristics of a non-competitive antagonist of nAChR in A. suum, and enhances the inhibitory effect of monepantel. The combination of monepantel and carvacrol may be clinically very effective, and the carvacrol molecule itself can be used as a promising platform for the development of new anthelmintic drugs.",
publisher = "Elsevier, Amsterdam",
journal = "Veterinary Parasitology",
title = "Carvacrol acts as a potent selective antagonist of different types of nicotinic acetylcholine receptors and enhances the effect of monepantel in the parasitic nematode Ascaris suum",
volume = "278",
pages = "UNSP 109031",
doi = "10.1016/j.vetpar.2020.109031"
}

Marjanović, Đ., Zdravković, N., Milovanović, M., Nedeljković-Trailović, J., Robertson, A. P., Todorović, Z.,& Trailović, S.. (2020). Carvacrol acts as a potent selective antagonist of different types of nicotinic acetylcholine receptors and enhances the effect of monepantel in the parasitic nematode Ascaris suum. in Veterinary Parasitology
Elsevier, Amsterdam., 278, UNSP 109031.
https://doi.org/10.1016/j.vetpar.2020.109031

Marjanović Đ, Zdravković N, Milovanović M, Nedeljković-Trailović J, Robertson AP, Todorović Z, Trailović S. Carvacrol acts as a potent selective antagonist of different types of nicotinic acetylcholine receptors and enhances the effect of monepantel in the parasitic nematode Ascaris suum. in Veterinary Parasitology. 2020;278:UNSP 109031.
doi:10.1016/j.vetpar.2020.109031 .

Marjanović, Đorđe, Zdravković, Nemanja, Milovanović, Mirjana, Nedeljković-Trailović, Jelena, Robertson, Alan P., Todorović, Zoran, Trailović, Saša, "Carvacrol acts as a potent selective antagonist of different types of nicotinic acetylcholine receptors and enhances the effect of monepantel in the parasitic nematode Ascaris suum" in Veterinary Parasitology, 278 (2020):UNSP 109031,
https://doi.org/10.1016/j.vetpar.2020.109031 . .

TY  - JOUR
AU  - Trailović, Saša
AU  - Marjanović, Đorđe
AU  - Vidonja-Uzelac, Teodora
AU  - Milovanović, Mirjana
AU  - Nedeljković-Trailović, Jelena
PY  - 2017
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/1468
AB  - Acute poisoning with OPs may lead to a range of neurological effects, which cannot be explained by AChE inhibition alone. Several OPs interact directly with cholinergic receptors in mammals, but such data does not exist for invertebrates. The aim of current study was to investigate the direct and indirect effects of diazinon on the contractions of rat ileum and to compare those effects on the nervemuscle preparation of the Ascaris suum. In the presence of increasing concentrations of diazinon (3, 10 and 30 nM), EFS-induced ileal contractions were increased significantly. In the same preparation, diazinon 3 nM, significantly increased contractions induced by EFS, but did not affect the contractions caused by 5MFI. Contrarily, 1 mu M of diazinon significantly and reversibly inhibited the EFS-induced ileal contractions. Diazinon exhibited competitive and non-competitive inhibitions of 5MFI induced contractions. The control EC50 of 5MFI was 2.48 mu M with R-max = 1.88 g. In the presence of diazinon, EC50 was 12.45 mu M, while R-max was reduced to 0.43 g. After washing, the EC50 and R-max values were again closer to the control level (3.80 mu M and 1.04 g). Diazinon 1 mu M did not inhibit Ascaris suum contractions caused by ACh, but it increased the R-max. Diazinon in our study exhibits two opposite effects on the motor activity of the ileum. In low nanomolar concentrations the dominat is its effect on AChE and the stimulation of contractions. Furthermore, in concentrations that approach micromolar values diazinon has a direct inhibitory effect on muscarinic receptors. The direct inhibitory effect of diazinon on A. suum contractions was not found.
PB  - Elsevier Sci Ltd, Oxford
T2  - Research in Veterinary Science
T1  - Two opposite dose-dependent effects of diazinon on the motor activity of the rat ileum
VL  - 112
SP  - 18
EP  - 25
DO  - 10.1016/j.rvsc.2017.01.002
ER  - 

@article{
author = "Trailović, Saša and Marjanović, Đorđe and Vidonja-Uzelac, Teodora and Milovanović, Mirjana and Nedeljković-Trailović, Jelena",
year = "2017",
abstract = "Acute poisoning with OPs may lead to a range of neurological effects, which cannot be explained by AChE inhibition alone. Several OPs interact directly with cholinergic receptors in mammals, but such data does not exist for invertebrates. The aim of current study was to investigate the direct and indirect effects of diazinon on the contractions of rat ileum and to compare those effects on the nervemuscle preparation of the Ascaris suum. In the presence of increasing concentrations of diazinon (3, 10 and 30 nM), EFS-induced ileal contractions were increased significantly. In the same preparation, diazinon 3 nM, significantly increased contractions induced by EFS, but did not affect the contractions caused by 5MFI. Contrarily, 1 mu M of diazinon significantly and reversibly inhibited the EFS-induced ileal contractions. Diazinon exhibited competitive and non-competitive inhibitions of 5MFI induced contractions. The control EC50 of 5MFI was 2.48 mu M with R-max = 1.88 g. In the presence of diazinon, EC50 was 12.45 mu M, while R-max was reduced to 0.43 g. After washing, the EC50 and R-max values were again closer to the control level (3.80 mu M and 1.04 g). Diazinon 1 mu M did not inhibit Ascaris suum contractions caused by ACh, but it increased the R-max. Diazinon in our study exhibits two opposite effects on the motor activity of the ileum. In low nanomolar concentrations the dominat is its effect on AChE and the stimulation of contractions. Furthermore, in concentrations that approach micromolar values diazinon has a direct inhibitory effect on muscarinic receptors. The direct inhibitory effect of diazinon on A. suum contractions was not found.",
publisher = "Elsevier Sci Ltd, Oxford",
journal = "Research in Veterinary Science",
title = "Two opposite dose-dependent effects of diazinon on the motor activity of the rat ileum",
volume = "112",
pages = "18-25",
doi = "10.1016/j.rvsc.2017.01.002"
}

Trailović, S., Marjanović, Đ., Vidonja-Uzelac, T., Milovanović, M.,& Nedeljković-Trailović, J.. (2017). Two opposite dose-dependent effects of diazinon on the motor activity of the rat ileum. in Research in Veterinary Science
Elsevier Sci Ltd, Oxford., 112, 18-25.
https://doi.org/10.1016/j.rvsc.2017.01.002

Trailović S, Marjanović Đ, Vidonja-Uzelac T, Milovanović M, Nedeljković-Trailović J. Two opposite dose-dependent effects of diazinon on the motor activity of the rat ileum. in Research in Veterinary Science. 2017;112:18-25.
doi:10.1016/j.rvsc.2017.01.002 .

Trailović, Saša, Marjanović, Đorđe, Vidonja-Uzelac, Teodora, Milovanović, Mirjana, Nedeljković-Trailović, Jelena, "Two opposite dose-dependent effects of diazinon on the motor activity of the rat ileum" in Research in Veterinary Science, 112 (2017):18-25,
https://doi.org/10.1016/j.rvsc.2017.01.002 . .

TY  - JOUR
AU  - Milovanović, Mirjana
AU  - Milosavljević, Miloš
AU  - Marjanović, Đorđe
AU  - Trailović, Saša
AU  - Vučinić, Marijana
AU  - Nedeljković-Trailović, Jelena
AU  - Marković, Maja
AU  - Đurđević, Dragan
PY  - 2016
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/1354
AB  - Carvacrol is a monoterpenic phenol and an active ingredient of the plant essential oils of the family Lamiaceae. We have investigated the analgesic effect of carvacrol, the possible dependence of the effect in relation to animal sex, and the impact of carvacrol on motor coordination in rats. Hyperalgesia was induced by formalin (1.5%), which was administered SC in the upper lip of rat. Hyperalgesia and effects of carvacrol and indomethacin were measured by using the orofacial formalin test. The influence on motor coordination in animals treated with carvacrol was investigated by using the rota-rod test. Carvacrol administered PO in pre-treatment (45 min. prior to formalin) at a single dose of 50, 75 and 100 mg /kg BW, in the male, 50 and 100 mg /kg BW, in female rats caused a dose-dependent antinociceptive effect. This effect of carvacrol was significantly higher (P lt 0.01, P lt 0.001) in male rats. Compared with indomethacin administered during pre-treatment (2 mg/kg, PO), carvacrol (100 mg/kg) exhibits significantly higher (P  lt 0.05 and P  lt 0.001) antinociceptive effect on formalininduced hyperalgesia in male rats. In the rota-rod test carvacrol did not disturb the motor coordination in male rats, nor the dose of carvacrol with clear antinociceptive properties exhibited depressive effect on the CNS of treated rats. Keeping in mind that the monoterpene carvacrol is of plant origin, with potentially less side effects and without residues, it is realistic to expect the possibility of its therapeutic use in the treatment of inflammatory pain in animals.
AB  - Karvakrol je monoterpenski fenol i sastavni je deo esencijalnih ulja biljaka iz familije Lamiaceae. Cilj ovog istraživanja bio je da se ispita analgetičko dejstvo karvakrola, moguće razlike u farmakološkom odgovoru između polova, i uticaj karvakrola na koordinaciju kretanja kod pacova. Hiperalgezija je izazvana formalinom (1,5%) koji je aplikovan s.c. u gornju usnu pacova. Hiperalgezija i efekti karvakrola i indometacina mereni su orofacijalnim formalinskim testom. Uticaj na motornu koordinaciju kod životinja tretiranih karvakrolom ispitali smo rota-rod testom. Karvakrol primenjen p.o. u pretretmanu (45 min. pre aplikacije formalina) u dozi od 50, 75 i 100 mg/kg t.m. kod mužjaka i dozi od 50 i 100 mg/kg t.m. kod ženki pacova, prouzrokuje dozno zavisan antinociceptivni efekat. Ovaj efekat karvakrola je značajno veći (P lt 0,01, P lt 0,001) kod pacova muškog pola. U poređenju sa indometacinom aplikovanim u pretretmanu (2 mg/kg, p.o.), karvakrol (100 mg/kg) ispoljava značajno veći (P lt 0,05 i P lt 0,001) antinociceptivni efekat na formalinom izazvanu hiperalgeziju kod mužjaka pacova. U rota-rod testu karvakrol nije narušio motornu koordinaciju kod mužjka pacova, niti doza karvakrol sa jasnim antinociceptivnim svojstvima deluje depresivno na CNS tretiranih pacova. Imajući u vidu da je karvakrol monoterpen biljnog porekla sa malo potencijalnih neželjenih dejstava i bez rezidua, realno je očekivati mogućnost njegove primenu u terapiji inflamatornog bola kod životinja.
PB  - Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd
T2  - Acta Veterinaria-Beograd
T1  - The effect of carvacrol on inflammatory pain and motor coordination in rats
T1  - Uticaj karvakrola na inflamatorni bol i koordinaciju kretanja kod pacova
VL  - 66
IS  - 4
SP  - 478
EP  - 488
DO  - 10.1515/acve-2016-0041
ER  - 

@article{
author = "Milovanović, Mirjana and Milosavljević, Miloš and Marjanović, Đorđe and Trailović, Saša and Vučinić, Marijana and Nedeljković-Trailović, Jelena and Marković, Maja and Đurđević, Dragan",
year = "2016",
abstract = "Carvacrol is a monoterpenic phenol and an active ingredient of the plant essential oils of the family Lamiaceae. We have investigated the analgesic effect of carvacrol, the possible dependence of the effect in relation to animal sex, and the impact of carvacrol on motor coordination in rats. Hyperalgesia was induced by formalin (1.5%), which was administered SC in the upper lip of rat. Hyperalgesia and effects of carvacrol and indomethacin were measured by using the orofacial formalin test. The influence on motor coordination in animals treated with carvacrol was investigated by using the rota-rod test. Carvacrol administered PO in pre-treatment (45 min. prior to formalin) at a single dose of 50, 75 and 100 mg /kg BW, in the male, 50 and 100 mg /kg BW, in female rats caused a dose-dependent antinociceptive effect. This effect of carvacrol was significantly higher (P lt 0.01, P lt 0.001) in male rats. Compared with indomethacin administered during pre-treatment (2 mg/kg, PO), carvacrol (100 mg/kg) exhibits significantly higher (P  lt 0.05 and P  lt 0.001) antinociceptive effect on formalininduced hyperalgesia in male rats. In the rota-rod test carvacrol did not disturb the motor coordination in male rats, nor the dose of carvacrol with clear antinociceptive properties exhibited depressive effect on the CNS of treated rats. Keeping in mind that the monoterpene carvacrol is of plant origin, with potentially less side effects and without residues, it is realistic to expect the possibility of its therapeutic use in the treatment of inflammatory pain in animals., Karvakrol je monoterpenski fenol i sastavni je deo esencijalnih ulja biljaka iz familije Lamiaceae. Cilj ovog istraživanja bio je da se ispita analgetičko dejstvo karvakrola, moguće razlike u farmakološkom odgovoru između polova, i uticaj karvakrola na koordinaciju kretanja kod pacova. Hiperalgezija je izazvana formalinom (1,5%) koji je aplikovan s.c. u gornju usnu pacova. Hiperalgezija i efekti karvakrola i indometacina mereni su orofacijalnim formalinskim testom. Uticaj na motornu koordinaciju kod životinja tretiranih karvakrolom ispitali smo rota-rod testom. Karvakrol primenjen p.o. u pretretmanu (45 min. pre aplikacije formalina) u dozi od 50, 75 i 100 mg/kg t.m. kod mužjaka i dozi od 50 i 100 mg/kg t.m. kod ženki pacova, prouzrokuje dozno zavisan antinociceptivni efekat. Ovaj efekat karvakrola je značajno veći (P lt 0,01, P lt 0,001) kod pacova muškog pola. U poređenju sa indometacinom aplikovanim u pretretmanu (2 mg/kg, p.o.), karvakrol (100 mg/kg) ispoljava značajno veći (P lt 0,05 i P lt 0,001) antinociceptivni efekat na formalinom izazvanu hiperalgeziju kod mužjaka pacova. U rota-rod testu karvakrol nije narušio motornu koordinaciju kod mužjka pacova, niti doza karvakrol sa jasnim antinociceptivnim svojstvima deluje depresivno na CNS tretiranih pacova. Imajući u vidu da je karvakrol monoterpen biljnog porekla sa malo potencijalnih neželjenih dejstava i bez rezidua, realno je očekivati mogućnost njegove primenu u terapiji inflamatornog bola kod životinja.",
publisher = "Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd",
journal = "Acta Veterinaria-Beograd",
title = "The effect of carvacrol on inflammatory pain and motor coordination in rats, Uticaj karvakrola na inflamatorni bol i koordinaciju kretanja kod pacova",
volume = "66",
number = "4",
pages = "478-488",
doi = "10.1515/acve-2016-0041"
}

Milovanović, M., Milosavljević, M., Marjanović, Đ., Trailović, S., Vučinić, M., Nedeljković-Trailović, J., Marković, M.,& Đurđević, D.. (2016). The effect of carvacrol on inflammatory pain and motor coordination in rats. in Acta Veterinaria-Beograd
Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd., 66(4), 478-488.
https://doi.org/10.1515/acve-2016-0041

Milovanović M, Milosavljević M, Marjanović Đ, Trailović S, Vučinić M, Nedeljković-Trailović J, Marković M, Đurđević D. The effect of carvacrol on inflammatory pain and motor coordination in rats. in Acta Veterinaria-Beograd. 2016;66(4):478-488.
doi:10.1515/acve-2016-0041 .

Milovanović, Mirjana, Milosavljević, Miloš, Marjanović, Đorđe, Trailović, Saša, Vučinić, Marijana, Nedeljković-Trailović, Jelena, Marković, Maja, Đurđević, Dragan, "The effect of carvacrol on inflammatory pain and motor coordination in rats" in Acta Veterinaria-Beograd, 66, no. 4 (2016):478-488,
https://doi.org/10.1515/acve-2016-0041 . .

TY  - JOUR
AU  - Tolimir, Nataša
AU  - Skrbić, Zdenka
AU  - Rajković, Borislav
AU  - Nedeljković-Trailović, Jelena
AU  - Maslovarić, Marijana
PY  - 2016
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/1322
AB  - To investigate consumers' attitudes towards a balanced diet and eggs as foodstuff, 509 consumers have been surveyed. Through this survey, the consumers answered questions about the importance of a balanced diet, importance of having eggs in diet, the most common way of egg consumption, benefits and drawbacks of eating eggs. The responses were analysed by gender, age, occupation, education and place of living of the respondents (city of Belgrade, other cities and other populated places). Based on these results, it can be concluded that most of the respondents (79% males and 87% females) think a balanced diet is important, whereas 41% males and 52% females think it is very important. Moreover, most of the respondents find it important to have eggs in diet, and males and females do not differ in their responses (69%). The most common way of cooking and consuming eggs is frying, according to 68% male and 50% female respondents from all the places (60% from Belgrade, 55% from other cities and 62% from other populated places). As a benefit of eating eggs, the most frequent response is 'nutritive value' (43% respondents), whereas, the most frequent drawback is 'a risk of cholesterol' (19% respondents). Hence, one should pay particular attention to education on the importance of diet, at the level of the whole community.
AB  - U cilju ispitivanja stavova potrošača o značaju uravnotežene ishrane i jajima kao namirnici anketirano je 509 potrošača, na području Republike Srbije. Kroz anketno ispitivanje potrošači su se izjasnili o značaju uravnotežene ishrane, značaju jaja u ishrani i najčešćim načinima konzumiranja, prednostima i nedostacima jaja. Odgovori anketiranih potrošača obrađeni su po polu, starosti, zanimanju, obrazovanju i sredini u kojoj žive (grad Beograd, ostali gradovi, ostala naseljena mesta). Na osnovu rezultata ispitivanja može se zaključiti da je većini anketiranih potrošača važna uravnotežena ishrana (79% za muški i 87% za ženski pol), pri čemu se o ishrani kao veoma važnoj izjasnilo 41% muškaraca i 52% žena. Takođe, za većinu anketiranih potrošača zastupljenost jaja u ishrani je važna, a po ovom pitanju među pripadnicima različitih polova nema razlika (69%). Najčešći način pripreme, odnosno konzumiranja, su pržena jaja, kod oba pola (za muškarce je to 68%, a kod žena 50%) i u svim životnim sredinama u Beogradu 60%, ostalim gradovima 55% i ostalim naseljenim mestima 62%). Kao prednost jaja u ishrani potrošači su najčešće naveli hranljivost (43% ispitanika), a kao najčešći nedostatak strah od povećanja holesterola (19% ispitanika). Edukaciji o značaju ishrane, sa akcentom na značaj jaja kao visokovredne namirnice, trebalo bi posvetiti posebnu pažnju, na nivou celokupne društvene zajednice.
PB  - Institut za stočarstvo, Beograd
T2  - Biotechnology in Animal Husbandry
T1  - Attittudes of consumers in Serbia towards the importance of a balanced diet and table egggs as foodstuff
T1  - Stavovi potrošača u Srbiji o značaju uravnotežene ishrane i konzumnim jajima kao namirnici
VL  - 32
IS  - 2
SP  - 205
EP  - 218
DO  - 10.2298/BAH1602205T
ER  - 

@article{
author = "Tolimir, Nataša and Skrbić, Zdenka and Rajković, Borislav and Nedeljković-Trailović, Jelena and Maslovarić, Marijana",
year = "2016",
abstract = "To investigate consumers' attitudes towards a balanced diet and eggs as foodstuff, 509 consumers have been surveyed. Through this survey, the consumers answered questions about the importance of a balanced diet, importance of having eggs in diet, the most common way of egg consumption, benefits and drawbacks of eating eggs. The responses were analysed by gender, age, occupation, education and place of living of the respondents (city of Belgrade, other cities and other populated places). Based on these results, it can be concluded that most of the respondents (79% males and 87% females) think a balanced diet is important, whereas 41% males and 52% females think it is very important. Moreover, most of the respondents find it important to have eggs in diet, and males and females do not differ in their responses (69%). The most common way of cooking and consuming eggs is frying, according to 68% male and 50% female respondents from all the places (60% from Belgrade, 55% from other cities and 62% from other populated places). As a benefit of eating eggs, the most frequent response is 'nutritive value' (43% respondents), whereas, the most frequent drawback is 'a risk of cholesterol' (19% respondents). Hence, one should pay particular attention to education on the importance of diet, at the level of the whole community., U cilju ispitivanja stavova potrošača o značaju uravnotežene ishrane i jajima kao namirnici anketirano je 509 potrošača, na području Republike Srbije. Kroz anketno ispitivanje potrošači su se izjasnili o značaju uravnotežene ishrane, značaju jaja u ishrani i najčešćim načinima konzumiranja, prednostima i nedostacima jaja. Odgovori anketiranih potrošača obrađeni su po polu, starosti, zanimanju, obrazovanju i sredini u kojoj žive (grad Beograd, ostali gradovi, ostala naseljena mesta). Na osnovu rezultata ispitivanja može se zaključiti da je većini anketiranih potrošača važna uravnotežena ishrana (79% za muški i 87% za ženski pol), pri čemu se o ishrani kao veoma važnoj izjasnilo 41% muškaraca i 52% žena. Takođe, za većinu anketiranih potrošača zastupljenost jaja u ishrani je važna, a po ovom pitanju među pripadnicima različitih polova nema razlika (69%). Najčešći način pripreme, odnosno konzumiranja, su pržena jaja, kod oba pola (za muškarce je to 68%, a kod žena 50%) i u svim životnim sredinama u Beogradu 60%, ostalim gradovima 55% i ostalim naseljenim mestima 62%). Kao prednost jaja u ishrani potrošači su najčešće naveli hranljivost (43% ispitanika), a kao najčešći nedostatak strah od povećanja holesterola (19% ispitanika). Edukaciji o značaju ishrane, sa akcentom na značaj jaja kao visokovredne namirnice, trebalo bi posvetiti posebnu pažnju, na nivou celokupne društvene zajednice.",
publisher = "Institut za stočarstvo, Beograd",
journal = "Biotechnology in Animal Husbandry",
title = "Attittudes of consumers in Serbia towards the importance of a balanced diet and table egggs as foodstuff, Stavovi potrošača u Srbiji o značaju uravnotežene ishrane i konzumnim jajima kao namirnici",
volume = "32",
number = "2",
pages = "205-218",
doi = "10.2298/BAH1602205T"
}

Tolimir, N., Skrbić, Z., Rajković, B., Nedeljković-Trailović, J.,& Maslovarić, M.. (2016). Attittudes of consumers in Serbia towards the importance of a balanced diet and table egggs as foodstuff. in Biotechnology in Animal Husbandry
Institut za stočarstvo, Beograd., 32(2), 205-218.
https://doi.org/10.2298/BAH1602205T

Tolimir N, Skrbić Z, Rajković B, Nedeljković-Trailović J, Maslovarić M. Attittudes of consumers in Serbia towards the importance of a balanced diet and table egggs as foodstuff. in Biotechnology in Animal Husbandry. 2016;32(2):205-218.
doi:10.2298/BAH1602205T .

Tolimir, Nataša, Skrbić, Zdenka, Rajković, Borislav, Nedeljković-Trailović, Jelena, Maslovarić, Marijana, "Attittudes of consumers in Serbia towards the importance of a balanced diet and table egggs as foodstuff" in Biotechnology in Animal Husbandry, 32, no. 2 (2016):205-218,
https://doi.org/10.2298/BAH1602205T . .

TY  - JOUR
AU  - Trailović, Saša
AU  - Sapundžić Zurovac, Zorana
AU  - Gruborović, S.
AU  - Marjanović, Đorđe
AU  - Nedeljković-Trailović, Jelena
PY  - 2016
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/1425
AB  - The aim of this study was to determine the role in contractions of postsynaptic nicotinic acetylcholine (nACh) and gamma- aminobutyric acid (GABA) receptors, in the bag region of Ascaris suum muscle cells, as well as the role of synaptic receptors between interneurons and motor neurons in the dorsal and ventral nerve cord. We have measured the isometric contractions of isolated segments of A. suum, with or without the nerve cord (dorsal or ventral). Contractions were caused by increasing concentrations of ACh or by electrical field stimulation (EFS). Based on our results, the presence of the nerve cord is essential for the contractile effects of ACh. The EC50 value of ACh for innervated muscle strips was 10.88 mu M. Unlike intact (innervated) preparations, there was no contraction of the muscle flaps when the nerve cord was mechanically removed. Furthermore, continuous EFS produced stable contractions of innervated muscle strips, but they are not sensitive to mecamylamine (100 mu M). However, GABA (30 mu M) significantly inhibited the EFS- induced contractions. EFS with the same characteristics did not cause muscle contractions of denervated muscle strips, but EFS with a wider pulse induced the increasing of tone and irregular contractions. These contractions were completely insensitive to the effect of GABA. The EC50 for ACh did not differ between the dorsal and ventral segments (9.83 mu M and 9.45 mu M), while GABA exhibited features of competitive and noncompetitive antagonists, regardless of whether it acted on the dorsal or ventral segments of A. suum. It is obvious that drugs will be more effective if they act on both the synaptic and extrasynaptic nACh and GABA receptors.
PB  - Cambridge Univ Press, Cambridge
T2  - Journal of Helminthology
T1  - Presynaptic and postsynaptic regulation of muscle contractions in the ascarid nematode Ascaris suum: a target for drug action
VL  - 90
IS  - 6
SP  - 698
EP  - 705
DO  - 10.1017/S0022149X15000978
ER  - 

@article{
author = "Trailović, Saša and Sapundžić Zurovac, Zorana and Gruborović, S. and Marjanović, Đorđe and Nedeljković-Trailović, Jelena",
year = "2016",
abstract = "The aim of this study was to determine the role in contractions of postsynaptic nicotinic acetylcholine (nACh) and gamma- aminobutyric acid (GABA) receptors, in the bag region of Ascaris suum muscle cells, as well as the role of synaptic receptors between interneurons and motor neurons in the dorsal and ventral nerve cord. We have measured the isometric contractions of isolated segments of A. suum, with or without the nerve cord (dorsal or ventral). Contractions were caused by increasing concentrations of ACh or by electrical field stimulation (EFS). Based on our results, the presence of the nerve cord is essential for the contractile effects of ACh. The EC50 value of ACh for innervated muscle strips was 10.88 mu M. Unlike intact (innervated) preparations, there was no contraction of the muscle flaps when the nerve cord was mechanically removed. Furthermore, continuous EFS produced stable contractions of innervated muscle strips, but they are not sensitive to mecamylamine (100 mu M). However, GABA (30 mu M) significantly inhibited the EFS- induced contractions. EFS with the same characteristics did not cause muscle contractions of denervated muscle strips, but EFS with a wider pulse induced the increasing of tone and irregular contractions. These contractions were completely insensitive to the effect of GABA. The EC50 for ACh did not differ between the dorsal and ventral segments (9.83 mu M and 9.45 mu M), while GABA exhibited features of competitive and noncompetitive antagonists, regardless of whether it acted on the dorsal or ventral segments of A. suum. It is obvious that drugs will be more effective if they act on both the synaptic and extrasynaptic nACh and GABA receptors.",
publisher = "Cambridge Univ Press, Cambridge",
journal = "Journal of Helminthology",
title = "Presynaptic and postsynaptic regulation of muscle contractions in the ascarid nematode Ascaris suum: a target for drug action",
volume = "90",
number = "6",
pages = "698-705",
doi = "10.1017/S0022149X15000978"
}

Trailović, S., Sapundžić Zurovac, Z., Gruborović, S., Marjanović, Đ.,& Nedeljković-Trailović, J.. (2016). Presynaptic and postsynaptic regulation of muscle contractions in the ascarid nematode Ascaris suum: a target for drug action. in Journal of Helminthology
Cambridge Univ Press, Cambridge., 90(6), 698-705.
https://doi.org/10.1017/S0022149X15000978

Trailović S, Sapundžić Zurovac Z, Gruborović S, Marjanović Đ, Nedeljković-Trailović J. Presynaptic and postsynaptic regulation of muscle contractions in the ascarid nematode Ascaris suum: a target for drug action. in Journal of Helminthology. 2016;90(6):698-705.
doi:10.1017/S0022149X15000978 .

Trailović, Saša, Sapundžić Zurovac, Zorana, Gruborović, S., Marjanović, Đorđe, Nedeljković-Trailović, Jelena, "Presynaptic and postsynaptic regulation of muscle contractions in the ascarid nematode Ascaris suum: a target for drug action" in Journal of Helminthology, 90, no. 6 (2016):698-705,
https://doi.org/10.1017/S0022149X15000978 . .

TY  - JOUR
AU  - Šefer, Dragan
AU  - Marković, Radmila
AU  - Nedeljković-Trailović, Jelena
AU  - Petrujkić, Branko
AU  - Radulović, Stamen
AU  - Grdović, Svetlana
PY  - 2015
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/1206
AB  - Animal food has to incorporate multiple objectives, ie. it should provide good animal health, good production and reproductive performance, reduce pollution of the environment as well as have the impact on food of animal origin, by supplying it, in addition to basic nutrients, with certain useful substances that can act preventively on the occurrence of various diseases in humans in modern living conditions. This complex task implies the application of scientific knowledge concerning biotechnology in the field of animal feed production, and also includes the use of specific nutrients that are the result of the latest developments in specific disciplines such as molecular biology and genetic engineering. As a result of researches in these areas there were created some varieties of cereals and legumes with improved nutritional properties. On the other hand, obtaining a safe food of animal origin product imposes the use of substances of natural origin (such as probiotics, prebiotics, phytobiotics, enzymes, chelating forms ..), which provide better digestibility and more complete utilization of certain nutrients from the feedstuff. In this way, the quantity of undigested substances are significantly reduced as well as soil and the atmosphere pollution. The use of specific additives in animal nutrition resulting from biotechnological research is most frequent when a problem concerning certain level of production or animal health has to be overcome. This implies a group of non-nutritional ingredients which are aimed to regulate the digestive tract microflora, pH, weight gain, as well as to modify metabolic processes etc.
AB  - Hrana za životinje treba istovremeno da objedini više ciljeva, tj. treba da obezbedi dobro zdravlje životinja, dobre proizvodne i reproduktivne performanse, smanji zagađivanje čovekove okoline ali i da utiče na namirnice animalnog porekla, da ih pored osnovnih hranljivih materija, snabde i određenim korisnim materijama koje mogu da deluju preventivno na pojavu raznih oboljenja ljudi u savremenim uslovima življenja. Ovaj kompleksan zadatak podrazumeva primenu naučnih saznanja iz oblasti biotehnologije u proizvodnju hrane za životinje a takođe uključuje i upotrebu specifičnih hraniva nastalih kao rezultat najnovijih dostignuća iz pojedinih naučnih disciplina kao što su molekularna biologija i genetski inženjering. Kao rezultat istraživanja u ovim oblastima stvoreni su varijeteti žitarica i leguminoza sa poboljšanim nutritivnim svojstvima. Sa druge strane, da bi se dobio bezbedan proizvod, odnosno namirnica animalnog porekla, nameće se upotreba supstanci prirodnog porekla (kao što su probiotci, prebiotici, fitobiotici, enzimi, helati, …) koje će doprineti boljoj svarljivosti i potpunijem iskorišćavanju određenih hranljivih materija iz hraniva. Na taj način se u značajnoj meri smanjuje deo nesvarenih materija i zagađivanje zemljišta i atmosfere. vSpecifični dodaci u ishrani životinja, koji su proistekli iz biotehnoloških istraživanja najčešće se koriste da bi se prevazišli problemi u vezi sa određenim nivoom proizvodnje ili zdravstvenim stanjem životinja. Tu se ubraja grupa nehranidbenih ingredijenata koja reguliše mikrofloru digestivnog trakta, pH, prirast, modifikuje procese metabolizma i slično.
PB  - Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd
T2  - Veterinarski Glasnik
T1  - Primena biotehnologije u ishrani životinja
VL  - 69
IS  - 1-2
SP  - 127
EP  - 137
DO  - 10.2298/VETGL1502127S
ER  - 

@article{
author = "Šefer, Dragan and Marković, Radmila and Nedeljković-Trailović, Jelena and Petrujkić, Branko and Radulović, Stamen and Grdović, Svetlana",
year = "2015",
abstract = "Animal food has to incorporate multiple objectives, ie. it should provide good animal health, good production and reproductive performance, reduce pollution of the environment as well as have the impact on food of animal origin, by supplying it, in addition to basic nutrients, with certain useful substances that can act preventively on the occurrence of various diseases in humans in modern living conditions. This complex task implies the application of scientific knowledge concerning biotechnology in the field of animal feed production, and also includes the use of specific nutrients that are the result of the latest developments in specific disciplines such as molecular biology and genetic engineering. As a result of researches in these areas there were created some varieties of cereals and legumes with improved nutritional properties. On the other hand, obtaining a safe food of animal origin product imposes the use of substances of natural origin (such as probiotics, prebiotics, phytobiotics, enzymes, chelating forms ..), which provide better digestibility and more complete utilization of certain nutrients from the feedstuff. In this way, the quantity of undigested substances are significantly reduced as well as soil and the atmosphere pollution. The use of specific additives in animal nutrition resulting from biotechnological research is most frequent when a problem concerning certain level of production or animal health has to be overcome. This implies a group of non-nutritional ingredients which are aimed to regulate the digestive tract microflora, pH, weight gain, as well as to modify metabolic processes etc., Hrana za životinje treba istovremeno da objedini više ciljeva, tj. treba da obezbedi dobro zdravlje životinja, dobre proizvodne i reproduktivne performanse, smanji zagađivanje čovekove okoline ali i da utiče na namirnice animalnog porekla, da ih pored osnovnih hranljivih materija, snabde i određenim korisnim materijama koje mogu da deluju preventivno na pojavu raznih oboljenja ljudi u savremenim uslovima življenja. Ovaj kompleksan zadatak podrazumeva primenu naučnih saznanja iz oblasti biotehnologije u proizvodnju hrane za životinje a takođe uključuje i upotrebu specifičnih hraniva nastalih kao rezultat najnovijih dostignuća iz pojedinih naučnih disciplina kao što su molekularna biologija i genetski inženjering. Kao rezultat istraživanja u ovim oblastima stvoreni su varijeteti žitarica i leguminoza sa poboljšanim nutritivnim svojstvima. Sa druge strane, da bi se dobio bezbedan proizvod, odnosno namirnica animalnog porekla, nameće se upotreba supstanci prirodnog porekla (kao što su probiotci, prebiotici, fitobiotici, enzimi, helati, …) koje će doprineti boljoj svarljivosti i potpunijem iskorišćavanju određenih hranljivih materija iz hraniva. Na taj način se u značajnoj meri smanjuje deo nesvarenih materija i zagađivanje zemljišta i atmosfere. vSpecifični dodaci u ishrani životinja, koji su proistekli iz biotehnoloških istraživanja najčešće se koriste da bi se prevazišli problemi u vezi sa određenim nivoom proizvodnje ili zdravstvenim stanjem životinja. Tu se ubraja grupa nehranidbenih ingredijenata koja reguliše mikrofloru digestivnog trakta, pH, prirast, modifikuje procese metabolizma i slično.",
publisher = "Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd",
journal = "Veterinarski Glasnik",
title = "Primena biotehnologije u ishrani životinja",
volume = "69",
number = "1-2",
pages = "127-137",
doi = "10.2298/VETGL1502127S"
}

Šefer, D., Marković, R., Nedeljković-Trailović, J., Petrujkić, B., Radulović, S.,& Grdović, S.. (2015). Primena biotehnologije u ishrani životinja. in Veterinarski Glasnik
Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd., 69(1-2), 127-137.
https://doi.org/10.2298/VETGL1502127S

Šefer D, Marković R, Nedeljković-Trailović J, Petrujkić B, Radulović S, Grdović S. Primena biotehnologije u ishrani životinja. in Veterinarski Glasnik. 2015;69(1-2):127-137.
doi:10.2298/VETGL1502127S .

Šefer, Dragan, Marković, Radmila, Nedeljković-Trailović, Jelena, Petrujkić, Branko, Radulović, Stamen, Grdović, Svetlana, "Primena biotehnologije u ishrani životinja" in Veterinarski Glasnik, 69, no. 1-2 (2015):127-137,
https://doi.org/10.2298/VETGL1502127S . .

TY  - JOUR
AU  - Jovanović, M.
AU  - Trailović, Dragiša
AU  - Kukolj, Vladimir
AU  - Nešić, Slađan
AU  - Marinković, Darko
AU  - Nedeljković-Trailović, Jelena
AU  - Strajn, B. Jakovac
AU  - Milićević, Dragan
PY  - 2015
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/1287
AB  - This paper reports on an outbreak of fumonisin toxicosis in a stable with 100 horses. Twenty-one horses were affected and fifteen died within a month. The animals were not febrile and exhibited poor appetite, somnolence, head pressing, blindness, ataxia, lethargy, and seizures, ending with death. The post mortem examination of the head of one 18-month-old colt revealed large, bilateral, slightly asymmetrical large areas of necrosis of the cerebral white matter. The lesions involved the frontal, parietal and occipital lobes only. Histological findings revealed leukomalacia with necrosis, infiltration of macrophages, neutrophils and eosinophils, haemorrhage and oedema of the surrounding grey matter. In response to the pathological findings, which indicated equine leukoencephalomalacia (ELEM), feed samples from the premises were tested for fumonisin B-1 and B-2 (FB1 and FB2). The milled maize samples contained 6.0 mg/kg FB1 and 2.4 mg/kg FB2, while the maize bran contained 6.05 mg/kg FB1 and 1.68 mg/kg FB2. These findings confirmed the diagnosis of fumonisin toxicosis. Hence, this report indicates that Serbia is one of the few regions in Europe with proven cases of ELEM.
PB  - Wageningen Academic Publishers, Wageningen
T2  - World Mycotoxin Journal
T1  - An outbreak of fumonisin toxicosis in horses in Serbia
VL  - 8
IS  - 4
SP  - 387
EP  - 391
DO  - 10.3920/WMJ2014.1812
ER  - 

@article{
author = "Jovanović, M. and Trailović, Dragiša and Kukolj, Vladimir and Nešić, Slađan and Marinković, Darko and Nedeljković-Trailović, Jelena and Strajn, B. Jakovac and Milićević, Dragan",
year = "2015",
abstract = "This paper reports on an outbreak of fumonisin toxicosis in a stable with 100 horses. Twenty-one horses were affected and fifteen died within a month. The animals were not febrile and exhibited poor appetite, somnolence, head pressing, blindness, ataxia, lethargy, and seizures, ending with death. The post mortem examination of the head of one 18-month-old colt revealed large, bilateral, slightly asymmetrical large areas of necrosis of the cerebral white matter. The lesions involved the frontal, parietal and occipital lobes only. Histological findings revealed leukomalacia with necrosis, infiltration of macrophages, neutrophils and eosinophils, haemorrhage and oedema of the surrounding grey matter. In response to the pathological findings, which indicated equine leukoencephalomalacia (ELEM), feed samples from the premises were tested for fumonisin B-1 and B-2 (FB1 and FB2). The milled maize samples contained 6.0 mg/kg FB1 and 2.4 mg/kg FB2, while the maize bran contained 6.05 mg/kg FB1 and 1.68 mg/kg FB2. These findings confirmed the diagnosis of fumonisin toxicosis. Hence, this report indicates that Serbia is one of the few regions in Europe with proven cases of ELEM.",
publisher = "Wageningen Academic Publishers, Wageningen",
journal = "World Mycotoxin Journal",
title = "An outbreak of fumonisin toxicosis in horses in Serbia",
volume = "8",
number = "4",
pages = "387-391",
doi = "10.3920/WMJ2014.1812"
}

Jovanović, M., Trailović, D., Kukolj, V., Nešić, S., Marinković, D., Nedeljković-Trailović, J., Strajn, B. J.,& Milićević, D.. (2015). An outbreak of fumonisin toxicosis in horses in Serbia. in World Mycotoxin Journal
Wageningen Academic Publishers, Wageningen., 8(4), 387-391.
https://doi.org/10.3920/WMJ2014.1812

Jovanović M, Trailović D, Kukolj V, Nešić S, Marinković D, Nedeljković-Trailović J, Strajn BJ, Milićević D. An outbreak of fumonisin toxicosis in horses in Serbia. in World Mycotoxin Journal. 2015;8(4):387-391.
doi:10.3920/WMJ2014.1812 .

Jovanović, M., Trailović, Dragiša, Kukolj, Vladimir, Nešić, Slađan, Marinković, Darko, Nedeljković-Trailović, Jelena, Strajn, B. Jakovac, Milićević, Dragan, "An outbreak of fumonisin toxicosis in horses in Serbia" in World Mycotoxin Journal, 8, no. 4 (2015):387-391,
https://doi.org/10.3920/WMJ2014.1812 . .

TY  - JOUR
AU  - Trailović, Saša
AU  - Marinković, Darko
AU  - Nedeljković-Trailović, Jelena
AU  - Milovanović, Mirjana
AU  - Marjanović, Đorđe
AU  - Aničić, Milan
PY  - 2015
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/1314
AB  - Motility is required for feeding, reproduction and maintenance of the fluke in the hosts liver. According to that, the neuromuscular system can be an attractive drugable target for chemotherapy. Musculature of the Fascioloides magna is organized into three layers, an outer circular layer, beneath this layer the longitudinal layer, and third, the oblique, or diagonal layer underlies the longitudinal layer. In our study, the administration of atropine or caffeine did not cause classic muscle contractions of F. magna muscle strips. However, the Electrical Field Stimulation (EFS) induced stable and repeatable contractions, which enabled us to examine their sensitivity to the various substances. Acetylcholine (ACh) (300 mu M and 1 mM), caused only a slight relaxation, without affecting the amplitude of spontaneous contractions or the amplitude of contractions induced by EFS. Contrary to that, atropine (100 mu M) caused a significant increase in the basal tone and an increase of EFS-induced contractions. If acetylcholine is an inhibitory neurotransmitter in trematodes, the described effects of atropine are achieved by the blockade of inhibitory neurotransmission. On the other hand, with respect to the process of excitation-contraction coupling, the plant alkaloid ryanodine (30 mu M) significantly reduced the basal tone, as well as EFS-induced contractions of E magna muscle strips. Ryanodine inhibited the potentiating effect of atropine on the basal tone and contractions caused by EFS, which indicates that the contractile effect of atropine is dependent on Ca++ release from intracellular stores. Caffeine (500 mu M) caused relaxation of fluke muscle strips and at the same time significantly enhanced the EFS-induced contractions. Both effects of caffeine can be explained by entry of extracellular Ca++ into muscle cells. The muscle contractility of F. magna depends both on the entry of extracellular calcium, and calcium release from intracellular stores, which are under the control of RyRs. Our results also suggest that antitrematodal drugs could potentially be developed from substances with selective anti-cholinergic activity.
PB  - Academic Press Inc Elsevier Science, San Diego
T2  - Experimental Parasitology
T1  - Pharmacological and morphological characteristics of the muscular system of the giant liver fluke (Fascioloides magna - Bassi 1875)
VL  - 159
SP  - 136
EP  - 142
DO  - 10.1016/j.exppara.2015.09.012
ER  - 

@article{
author = "Trailović, Saša and Marinković, Darko and Nedeljković-Trailović, Jelena and Milovanović, Mirjana and Marjanović, Đorđe and Aničić, Milan",
year = "2015",
abstract = "Motility is required for feeding, reproduction and maintenance of the fluke in the hosts liver. According to that, the neuromuscular system can be an attractive drugable target for chemotherapy. Musculature of the Fascioloides magna is organized into three layers, an outer circular layer, beneath this layer the longitudinal layer, and third, the oblique, or diagonal layer underlies the longitudinal layer. In our study, the administration of atropine or caffeine did not cause classic muscle contractions of F. magna muscle strips. However, the Electrical Field Stimulation (EFS) induced stable and repeatable contractions, which enabled us to examine their sensitivity to the various substances. Acetylcholine (ACh) (300 mu M and 1 mM), caused only a slight relaxation, without affecting the amplitude of spontaneous contractions or the amplitude of contractions induced by EFS. Contrary to that, atropine (100 mu M) caused a significant increase in the basal tone and an increase of EFS-induced contractions. If acetylcholine is an inhibitory neurotransmitter in trematodes, the described effects of atropine are achieved by the blockade of inhibitory neurotransmission. On the other hand, with respect to the process of excitation-contraction coupling, the plant alkaloid ryanodine (30 mu M) significantly reduced the basal tone, as well as EFS-induced contractions of E magna muscle strips. Ryanodine inhibited the potentiating effect of atropine on the basal tone and contractions caused by EFS, which indicates that the contractile effect of atropine is dependent on Ca++ release from intracellular stores. Caffeine (500 mu M) caused relaxation of fluke muscle strips and at the same time significantly enhanced the EFS-induced contractions. Both effects of caffeine can be explained by entry of extracellular Ca++ into muscle cells. The muscle contractility of F. magna depends both on the entry of extracellular calcium, and calcium release from intracellular stores, which are under the control of RyRs. Our results also suggest that antitrematodal drugs could potentially be developed from substances with selective anti-cholinergic activity.",
publisher = "Academic Press Inc Elsevier Science, San Diego",
journal = "Experimental Parasitology",
title = "Pharmacological and morphological characteristics of the muscular system of the giant liver fluke (Fascioloides magna - Bassi 1875)",
volume = "159",
pages = "136-142",
doi = "10.1016/j.exppara.2015.09.012"
}

Trailović, S., Marinković, D., Nedeljković-Trailović, J., Milovanović, M., Marjanović, Đ.,& Aničić, M.. (2015). Pharmacological and morphological characteristics of the muscular system of the giant liver fluke (Fascioloides magna - Bassi 1875). in Experimental Parasitology
Academic Press Inc Elsevier Science, San Diego., 159, 136-142.
https://doi.org/10.1016/j.exppara.2015.09.012

Trailović S, Marinković D, Nedeljković-Trailović J, Milovanović M, Marjanović Đ, Aničić M. Pharmacological and morphological characteristics of the muscular system of the giant liver fluke (Fascioloides magna - Bassi 1875). in Experimental Parasitology. 2015;159:136-142.
doi:10.1016/j.exppara.2015.09.012 .

Trailović, Saša, Marinković, Darko, Nedeljković-Trailović, Jelena, Milovanović, Mirjana, Marjanović, Đorđe, Aničić, Milan, "Pharmacological and morphological characteristics of the muscular system of the giant liver fluke (Fascioloides magna - Bassi 1875)" in Experimental Parasitology, 159 (2015):136-142,
https://doi.org/10.1016/j.exppara.2015.09.012 . .

TY  - JOUR
AU  - Nedeljković-Trailović, Jelena
AU  - Trailović, Saša
AU  - Resanović, Radmila
AU  - Milićević, Dragan
AU  - Jovanović, Milijan
AU  - Vasiljević, Marko
PY  - 2015
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/1193
AB  - The aim of our study was to determine the efficacy of three different adsorbents, inorganic (modified zeolite), organic (esterified glucomannans) and mixed (inorganic and organic components, with the addition of enzymes), in protecting broilers from the toxic effects of ochratoxin A in feed. Broilers were fed diets containing 2 mg/kg of ochratoxin A (OTA) and supplemented with adsorbents at the recommended concentration of 2 g/kg for 21 days. The presence of OTA led to a notable reduction in body weight, lower weight gain, increased feed conversion and induced histopathological changes in the liver and kidneys. The presence of inorganic, organic and mixed adsorbents in contaminated feed only partially reduced the negative effects of OTA on the broiler performances. Broilers that were fed with adsorbent-supplemented feed reached higher body weight (17.96%, 19.09% and 13.59%), compared to the group that received only OTA. The presence of adsorbents partially alleviated the reduction in feed consumption (22.68%, 12.91% and 10.59%), and a similar effect was observed with feed conversion. The applied adsorbents have also reduced the intensity of histopathological changes caused by OTA; however, they were not able to prevent their onset. After the withdrawal of the toxin and adsorbents from the feed (21-42 days), all previously observed disturbances in broilers were reduced, but more remarkably in broilers fed with adsorbents.
PB  - MDPI, Basel
T2  - Toxins
T1  - Comparative Investigation of the Efficacy of Three Different Adsorbents against OTA-Induced Toxicity in Broiler Chickens
VL  - 7
IS  - 4
SP  - 1174
EP  - 1191
DO  - 10.3390/toxins7041174
ER  - 

@article{
author = "Nedeljković-Trailović, Jelena and Trailović, Saša and Resanović, Radmila and Milićević, Dragan and Jovanović, Milijan and Vasiljević, Marko",
year = "2015",
abstract = "The aim of our study was to determine the efficacy of three different adsorbents, inorganic (modified zeolite), organic (esterified glucomannans) and mixed (inorganic and organic components, with the addition of enzymes), in protecting broilers from the toxic effects of ochratoxin A in feed. Broilers were fed diets containing 2 mg/kg of ochratoxin A (OTA) and supplemented with adsorbents at the recommended concentration of 2 g/kg for 21 days. The presence of OTA led to a notable reduction in body weight, lower weight gain, increased feed conversion and induced histopathological changes in the liver and kidneys. The presence of inorganic, organic and mixed adsorbents in contaminated feed only partially reduced the negative effects of OTA on the broiler performances. Broilers that were fed with adsorbent-supplemented feed reached higher body weight (17.96%, 19.09% and 13.59%), compared to the group that received only OTA. The presence of adsorbents partially alleviated the reduction in feed consumption (22.68%, 12.91% and 10.59%), and a similar effect was observed with feed conversion. The applied adsorbents have also reduced the intensity of histopathological changes caused by OTA; however, they were not able to prevent their onset. After the withdrawal of the toxin and adsorbents from the feed (21-42 days), all previously observed disturbances in broilers were reduced, but more remarkably in broilers fed with adsorbents.",
publisher = "MDPI, Basel",
journal = "Toxins",
title = "Comparative Investigation of the Efficacy of Three Different Adsorbents against OTA-Induced Toxicity in Broiler Chickens",
volume = "7",
number = "4",
pages = "1174-1191",
doi = "10.3390/toxins7041174"
}

Nedeljković-Trailović, J., Trailović, S., Resanović, R., Milićević, D., Jovanović, M.,& Vasiljević, M.. (2015). Comparative Investigation of the Efficacy of Three Different Adsorbents against OTA-Induced Toxicity in Broiler Chickens. in Toxins
MDPI, Basel., 7(4), 1174-1191.
https://doi.org/10.3390/toxins7041174

Nedeljković-Trailović J, Trailović S, Resanović R, Milićević D, Jovanović M, Vasiljević M. Comparative Investigation of the Efficacy of Three Different Adsorbents against OTA-Induced Toxicity in Broiler Chickens. in Toxins. 2015;7(4):1174-1191.
doi:10.3390/toxins7041174 .

Nedeljković-Trailović, Jelena, Trailović, Saša, Resanović, Radmila, Milićević, Dragan, Jovanović, Milijan, Vasiljević, Marko, "Comparative Investigation of the Efficacy of Three Different Adsorbents against OTA-Induced Toxicity in Broiler Chickens" in Toxins, 7, no. 4 (2015):1174-1191,
https://doi.org/10.3390/toxins7041174 . .

TY  - CONF
AU  - Stefanović, Srđan
AU  - Spirić, Danka
AU  - Petronijević, Radivoj
AU  - Nedeljković-Trailović, Jelena
AU  - Milićević, Dragan
AU  - Nikolić, Dragica M.
AU  - Janković, Saša
PY  - 2015
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/1252
AB  - The aim of this paper is to assess the closeness of agreement between results of ELISA and LC-MS/MS methods for determination of aflatoxin B-1 in corn and aflatoxin M-1 in milk. Samples of corn (n=100) and milk (n=250) were simultaneously analyzed using ELISA and LC-MS/MS methods, after the severe drought that affected Serbia in summer 2012 resulting in occurrence of aflatoxin B1 in corn and aflatoxin M-1 in milk. Regression analysis showed higher level of agreement between aflatoxin B-1 samples (R2=0.994), compared to aflatoxin M-1 samples (r(2)=0.920). However, both techniques were satisfactory in meeting the requirements for official control purposes.
PB  - Elsevier Science Bv, Amsterdam
C3  - 58th International Meat Industry Conference (MEATCON2015)
T1  - Comparison of two analytical methods (ELISA and LC-MS/MS) for determination of aflatoxin B-1 in corn and aflatoxin M-1 in milk
VL  - 5
SP  - 270
EP  - 273
DO  - 10.1016/j.profoo.2015.09.077
ER  - 

@conference{
author = "Stefanović, Srđan and Spirić, Danka and Petronijević, Radivoj and Nedeljković-Trailović, Jelena and Milićević, Dragan and Nikolić, Dragica M. and Janković, Saša",
year = "2015",
abstract = "The aim of this paper is to assess the closeness of agreement between results of ELISA and LC-MS/MS methods for determination of aflatoxin B-1 in corn and aflatoxin M-1 in milk. Samples of corn (n=100) and milk (n=250) were simultaneously analyzed using ELISA and LC-MS/MS methods, after the severe drought that affected Serbia in summer 2012 resulting in occurrence of aflatoxin B1 in corn and aflatoxin M-1 in milk. Regression analysis showed higher level of agreement between aflatoxin B-1 samples (R2=0.994), compared to aflatoxin M-1 samples (r(2)=0.920). However, both techniques were satisfactory in meeting the requirements for official control purposes.",
publisher = "Elsevier Science Bv, Amsterdam",
journal = "58th International Meat Industry Conference (MEATCON2015)",
title = "Comparison of two analytical methods (ELISA and LC-MS/MS) for determination of aflatoxin B-1 in corn and aflatoxin M-1 in milk",
volume = "5",
pages = "270-273",
doi = "10.1016/j.profoo.2015.09.077"
}

Stefanović, S., Spirić, D., Petronijević, R., Nedeljković-Trailović, J., Milićević, D., Nikolić, D. M.,& Janković, S.. (2015). Comparison of two analytical methods (ELISA and LC-MS/MS) for determination of aflatoxin B-1 in corn and aflatoxin M-1 in milk. in 58th International Meat Industry Conference (MEATCON2015)
Elsevier Science Bv, Amsterdam., 5, 270-273.
https://doi.org/10.1016/j.profoo.2015.09.077

Stefanović S, Spirić D, Petronijević R, Nedeljković-Trailović J, Milićević D, Nikolić DM, Janković S. Comparison of two analytical methods (ELISA and LC-MS/MS) for determination of aflatoxin B-1 in corn and aflatoxin M-1 in milk. in 58th International Meat Industry Conference (MEATCON2015). 2015;5:270-273.
doi:10.1016/j.profoo.2015.09.077 .

Stefanović, Srđan, Spirić, Danka, Petronijević, Radivoj, Nedeljković-Trailović, Jelena, Milićević, Dragan, Nikolić, Dragica M., Janković, Saša, "Comparison of two analytical methods (ELISA and LC-MS/MS) for determination of aflatoxin B-1 in corn and aflatoxin M-1 in milk" in 58th International Meat Industry Conference (MEATCON2015), 5 (2015):270-273,
https://doi.org/10.1016/j.profoo.2015.09.077 . .

TY  - JOUR
AU  - Trailović, Saša
AU  - Marjanović, Đorđe
AU  - Nedeljković-Trailović, Jelena
AU  - Robertson, Alan P.
AU  - Martin, Richard J.
PY  - 2015
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/1290
AB  - Essential plant oils (or their active principles) are safe to use and a potentially attractive alternative to current antiparasitic drugs. In the present study, we tested the effects of carvacrol on the isolated tissues of Ascaris suum and investigated potential interactions with other antiparasitic drugs. We used somatic muscle flaps for contraction assays, as well as for electrophysiological investigations. Carvacrol 300 mu M highly significantly inhibited contractions caused by 1, 3, 10, 30, and 100 mu M of ACh (p = 0.0023, p = 0.0002, p = 0.0002, p < 0.0001, and p < 0.0001). The control EC50 for acetylcholine was 8.87 mu M (log EC50 = 0.95 +/- 0.26), while R (max) was 2.53 +/- 0.24 g. The EC50 of acetylcholine in the presence of 300 mu M of carvacrol was 27.71 mu M (log EC50 = 1.44 +/- 0.28) and the R (max) decreased to 1.63 +/- 0.32 g. Furthermore, carvacrol highly significant potentiates inhibitory effect of GABA and piperazine on the contractions induced by ACh. However, carvacrol (100 and 300 mu M), did not produce any changes in the membrane potential or conductance of the A. suum muscle cell. While, 300 mu M of carvacrol showed a significant inhibitory effect on ACh-induced depolarization response. The mean control depolarization was 13.58 +/- 0.66 mV and decreased in presence of carvacrol to 4.50 +/- 1.02 mV (p < 0.0001). Mean control Delta g was 0.168 +/- 0.017 mu S, while in the presence of 300 mu M of carvacrol, Delta g significantly decreased to 0.060 +/- 0.018 Delta S (p = 0.0017). The inhibitory effect on contractions may be the explanation of the antinematodal potential of carvacrol. Moreover, inhibition of depolarizations caused by ACh and reduction of conductance changes directly points to an interaction with the nAChR in A. suum.
PB  - Springer, New York
T2  - Parasitology Research
T1  - Interaction of carvacrol with the Ascaris suum nicotinic acetylcholine receptors and gamma-aminobutyric acid receptors, potential mechanism of antinematodal action
VL  - 114
IS  - 8
SP  - 3059
EP  - 3068
DO  - 10.1007/s00436-015-4508-x
ER  - 

@article{
author = "Trailović, Saša and Marjanović, Đorđe and Nedeljković-Trailović, Jelena and Robertson, Alan P. and Martin, Richard J.",
year = "2015",
abstract = "Essential plant oils (or their active principles) are safe to use and a potentially attractive alternative to current antiparasitic drugs. In the present study, we tested the effects of carvacrol on the isolated tissues of Ascaris suum and investigated potential interactions with other antiparasitic drugs. We used somatic muscle flaps for contraction assays, as well as for electrophysiological investigations. Carvacrol 300 mu M highly significantly inhibited contractions caused by 1, 3, 10, 30, and 100 mu M of ACh (p = 0.0023, p = 0.0002, p = 0.0002, p < 0.0001, and p < 0.0001). The control EC50 for acetylcholine was 8.87 mu M (log EC50 = 0.95 +/- 0.26), while R (max) was 2.53 +/- 0.24 g. The EC50 of acetylcholine in the presence of 300 mu M of carvacrol was 27.71 mu M (log EC50 = 1.44 +/- 0.28) and the R (max) decreased to 1.63 +/- 0.32 g. Furthermore, carvacrol highly significant potentiates inhibitory effect of GABA and piperazine on the contractions induced by ACh. However, carvacrol (100 and 300 mu M), did not produce any changes in the membrane potential or conductance of the A. suum muscle cell. While, 300 mu M of carvacrol showed a significant inhibitory effect on ACh-induced depolarization response. The mean control depolarization was 13.58 +/- 0.66 mV and decreased in presence of carvacrol to 4.50 +/- 1.02 mV (p < 0.0001). Mean control Delta g was 0.168 +/- 0.017 mu S, while in the presence of 300 mu M of carvacrol, Delta g significantly decreased to 0.060 +/- 0.018 Delta S (p = 0.0017). The inhibitory effect on contractions may be the explanation of the antinematodal potential of carvacrol. Moreover, inhibition of depolarizations caused by ACh and reduction of conductance changes directly points to an interaction with the nAChR in A. suum.",
publisher = "Springer, New York",
journal = "Parasitology Research",
title = "Interaction of carvacrol with the Ascaris suum nicotinic acetylcholine receptors and gamma-aminobutyric acid receptors, potential mechanism of antinematodal action",
volume = "114",
number = "8",
pages = "3059-3068",
doi = "10.1007/s00436-015-4508-x"
}

Trailović, S., Marjanović, Đ., Nedeljković-Trailović, J., Robertson, A. P.,& Martin, R. J.. (2015). Interaction of carvacrol with the Ascaris suum nicotinic acetylcholine receptors and gamma-aminobutyric acid receptors, potential mechanism of antinematodal action. in Parasitology Research
Springer, New York., 114(8), 3059-3068.
https://doi.org/10.1007/s00436-015-4508-x

Trailović S, Marjanović Đ, Nedeljković-Trailović J, Robertson AP, Martin RJ. Interaction of carvacrol with the Ascaris suum nicotinic acetylcholine receptors and gamma-aminobutyric acid receptors, potential mechanism of antinematodal action. in Parasitology Research. 2015;114(8):3059-3068.
doi:10.1007/s00436-015-4508-x .

Trailović, Saša, Marjanović, Đorđe, Nedeljković-Trailović, Jelena, Robertson, Alan P., Martin, Richard J., "Interaction of carvacrol with the Ascaris suum nicotinic acetylcholine receptors and gamma-aminobutyric acid receptors, potential mechanism of antinematodal action" in Parasitology Research, 114, no. 8 (2015):3059-3068,
https://doi.org/10.1007/s00436-015-4508-x . .

TY  - CONF
AU  - Šefer, Dragan
AU  - Grdović, Svetlana
AU  - Marković, Radmila
AU  - Nedeljković-Trailović, Jelena
AU  - Petrujkić, Branko
AU  - Radulović, Stamen
PY  - 2014
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/3369
PB  - Beograd : Srpsko veterinarsko društvo
C3  - 25. Savetovanje veterinara Srbije, Zlatibor, 11 - 14. septembar 2014
T1  - Primena biotehnologije u ishrani životinja
T1  - Application of biotechnology in animal nutrition
SP  - 37
EP  - 38
UR  - https://hdl.handle.net/21.15107/rcub_veterinar_3369
ER  - 

@conference{
author = "Šefer, Dragan and Grdović, Svetlana and Marković, Radmila and Nedeljković-Trailović, Jelena and Petrujkić, Branko and Radulović, Stamen",
year = "2014",
publisher = "Beograd : Srpsko veterinarsko društvo",
journal = "25. Savetovanje veterinara Srbije, Zlatibor, 11 - 14. septembar 2014",
title = "Primena biotehnologije u ishrani životinja, Application of biotechnology in animal nutrition",
pages = "37-38",
url = "https://hdl.handle.net/21.15107/rcub_veterinar_3369"
}

Šefer, D., Grdović, S., Marković, R., Nedeljković-Trailović, J., Petrujkić, B.,& Radulović, S.. (2014). Primena biotehnologije u ishrani životinja. in 25. Savetovanje veterinara Srbije, Zlatibor, 11 - 14. septembar 2014
Beograd : Srpsko veterinarsko društvo., 37-38.
https://hdl.handle.net/21.15107/rcub_veterinar_3369

Šefer D, Grdović S, Marković R, Nedeljković-Trailović J, Petrujkić B, Radulović S. Primena biotehnologije u ishrani životinja. in 25. Savetovanje veterinara Srbije, Zlatibor, 11 - 14. septembar 2014. 2014;:37-38.
https://hdl.handle.net/21.15107/rcub_veterinar_3369 .

Šefer, Dragan, Grdović, Svetlana, Marković, Radmila, Nedeljković-Trailović, Jelena, Petrujkić, Branko, Radulović, Stamen, "Primena biotehnologije u ishrani životinja" in 25. Savetovanje veterinara Srbije, Zlatibor, 11 - 14. septembar 2014 (2014):37-38,
https://hdl.handle.net/21.15107/rcub_veterinar_3369 .

TY  - JOUR
AU  - Milićević, Dragan
AU  - Vranić, Danijela
AU  - Masić, Zoran
AU  - Parunović, Nenad
AU  - Trbović, Dejana
AU  - Nedeljković-Trailović, Jelena
AU  - Petrović, Zoran
PY  - 2014
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/1106
AB  - Background: The objective of the study was to present information about the chemical composition, the fatty acids profile, and cholesterol content of chicken meat in order to investigate the impact of chicken meat consumption on cardiovascular risk in the general population. Methods: A total of 48 6-wk-old broiler chickens broilers from two farms in June to November of 2012, and February of 2013, were used in this trial. Total lipid content was determined by extraction of fat by petrol ether (Soxhlet) after acid hydrolysis of samples. Fatty acids were determined by capillary gas chromatography. Cholesterol determination was performed by using HPLC/PDA system. Results: The results indicate that the total free cholesterol content in raw breast and drumstick of chickens was in the range of 37,41-79,9 mg/100 g and 48,35-99,5 mg/100 g, respectively. The main fatty acids identified in all cuts were C18:1c9, C18:2n6, C16:0, C18:0, and C16:1. Decreasing the dietary n-6/n-3 clearly decreased the content in breast and drumstick muscle of C18:2n6, C18:3n3, and C20:3n6, but increased that of C16:0, C18:0, and C20:2. Also, the major saturated fatty acid (SFA) (C16:0 and C18:0) was significantly differ among the four treatments. Conclusion: Our study shows that dietary fat and fatty acid composition influence the concentrations of total cholesterol content, total fat content, and fatty acid composition in broiler muscle. This information will aid in determining the burden of chicken meat as a cardiovascular risk factors disease and act as a planning tool for public-health Programmes.
PB  - BMC, London
T2  - Lipids in Health and Disease
T1  - The role of total fats, saturated/unsaturated fatty acids and cholesterol content in chicken meat as cardiovascular risk factors
VL  - 13
SP  - 42
DO  - 10.1186/1476-511X-13-42
ER  - 

@article{
author = "Milićević, Dragan and Vranić, Danijela and Masić, Zoran and Parunović, Nenad and Trbović, Dejana and Nedeljković-Trailović, Jelena and Petrović, Zoran",
year = "2014",
abstract = "Background: The objective of the study was to present information about the chemical composition, the fatty acids profile, and cholesterol content of chicken meat in order to investigate the impact of chicken meat consumption on cardiovascular risk in the general population. Methods: A total of 48 6-wk-old broiler chickens broilers from two farms in June to November of 2012, and February of 2013, were used in this trial. Total lipid content was determined by extraction of fat by petrol ether (Soxhlet) after acid hydrolysis of samples. Fatty acids were determined by capillary gas chromatography. Cholesterol determination was performed by using HPLC/PDA system. Results: The results indicate that the total free cholesterol content in raw breast and drumstick of chickens was in the range of 37,41-79,9 mg/100 g and 48,35-99,5 mg/100 g, respectively. The main fatty acids identified in all cuts were C18:1c9, C18:2n6, C16:0, C18:0, and C16:1. Decreasing the dietary n-6/n-3 clearly decreased the content in breast and drumstick muscle of C18:2n6, C18:3n3, and C20:3n6, but increased that of C16:0, C18:0, and C20:2. Also, the major saturated fatty acid (SFA) (C16:0 and C18:0) was significantly differ among the four treatments. Conclusion: Our study shows that dietary fat and fatty acid composition influence the concentrations of total cholesterol content, total fat content, and fatty acid composition in broiler muscle. This information will aid in determining the burden of chicken meat as a cardiovascular risk factors disease and act as a planning tool for public-health Programmes.",
publisher = "BMC, London",
journal = "Lipids in Health and Disease",
title = "The role of total fats, saturated/unsaturated fatty acids and cholesterol content in chicken meat as cardiovascular risk factors",
volume = "13",
pages = "42",
doi = "10.1186/1476-511X-13-42"
}

Milićević, D., Vranić, D., Masić, Z., Parunović, N., Trbović, D., Nedeljković-Trailović, J.,& Petrović, Z.. (2014). The role of total fats, saturated/unsaturated fatty acids and cholesterol content in chicken meat as cardiovascular risk factors. in Lipids in Health and Disease
BMC, London., 13, 42.
https://doi.org/10.1186/1476-511X-13-42

Milićević D, Vranić D, Masić Z, Parunović N, Trbović D, Nedeljković-Trailović J, Petrović Z. The role of total fats, saturated/unsaturated fatty acids and cholesterol content in chicken meat as cardiovascular risk factors. in Lipids in Health and Disease. 2014;13:42.
doi:10.1186/1476-511X-13-42 .

Milićević, Dragan, Vranić, Danijela, Masić, Zoran, Parunović, Nenad, Trbović, Dejana, Nedeljković-Trailović, Jelena, Petrović, Zoran, "The role of total fats, saturated/unsaturated fatty acids and cholesterol content in chicken meat as cardiovascular risk factors" in Lipids in Health and Disease, 13 (2014):42,
https://doi.org/10.1186/1476-511X-13-42 . .

TY  - JOUR
AU  - Milićević, Dragan
AU  - Nedeljković-Trailović, Jelena
AU  - Mašić, Zoran
PY  - 2014
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/1162
AB  - Disease outbreaks due to the consumption of contaminated food and feedstuff are a recurring problem worldwide. The major factor contributing to contamination are microorganisms, especially fungi, which produce low-molecular-weight compounds as secondary metabolites, with confirmed toxic properties referred to as mycotoxins. Mycotoxins are toxic secondary metabolites produced by fungi that invade crops at the field level and may grow on foods during storage under favorable conditions. The toxigenic fungi of Aspergillus, Penicillium, Fusarium, Alternari and Clavicepshave genera are of the greatest consequence to food safety. Mycotoxins, of over 400 that are known, which have the most food safety, nutritive, ecologic and economic significance include the aflatoxins, ochratoxins, trichothecenes, zearalenone, fumonisins, tremorgenic mycotoxinsand ergotalcaloides. Some molds are capable of producing more than one mycotoxin and some mycotoxins are produced by more than one fungal species. Often more than one mycotoxin is found on a contaminated substrate. Factors influencing the presence of mycotoxins in foods or feeds include environmental conditions related to storage that can be controlled. Other extrinsic factors such as climate or intrinsic factors such as fungal strain specificity, strain variation, and instability of toxigenic properties are more difficult to control. Exposure to mycotoxins is mostly by ingestion, but also occurs by the dermal and inhalation routes. The diseases caused by exposure to mycotoxins are known as mycotoxicoses. Mycotoxins have various acute and chronic effects on humans and animals (especially monogastrics) depending on species and susceptibility of an animal within a species. Ruminants, however, are generally more resistant to the adverse effects of mycotoxins. This is because the rumen microbiota is capable of degrading mycotoxins. The economic impact of mycotoxins include loss of human and animal life, increased health care and veterinary care costs, reduced livestock production, disposal of contaminated foods and feeds, and investment in research and applications to reduce severity of the mycotoxin problem. This review is meant to be informative not only for health-conscious consumers but also for experts in the field to pave the way for future research to fill the existing gaps in our knowledge in regard to mycotoxins and food safety. In this review, the focus is on the occurrence of various types of mycotoxins in food and feed associated with risks to humans and livestock, as well as legislation put forth by various authorities. Brief descriptions on recent developments in mycotoxin detection methodology and on presently practiced detoxification methods are also included.
AB  - Oboljenja ljudi prouzrokovana kontaminiranom hranom predstavljaju jedan od najvećih problema sa kojim se suočava savremeno čovečanstvo. Glavni uzročnici kontaminacije su mikroorganizmi, naročito plesni, koje sintetišu jedinjenja male molekulske mase sa izrazitim toksičnim efektom na žive organizme. Mikotoksini su sekundarni metaboliti pretežno Aspergillus, Penicillium, Fusarium, Alternaria i Claviceps vrsta plesni, koje mogu kontaminirati hranu na polju (preharvest) i/ili tokom skladištenja (postharvest). Iako je do sada poznato preko 400 mikotoksina zbog svoje zastupljenosti i toksičnosti, afl atoksini (AFT), ohratoksin A (OTA), trihoteceni (TCT), zearalenon (ZEA), fumonizini (FB), tremorgeni mikotoksini i ergotalkaloidi, predstavljaju najveći medicinski, nutritivni, ekološki i ekonomski problem. Specifičnost mikotoksina u odnosu na druge toksine ogleda se u tome da pojedini rodovi plesni mogu da sintetišu nekoliko mikotoksina, kao i to da pojedini mikotoksini mogu biti proizvod sekundarnog metabolizma nekoliko rodova i vrsta plesni. S toga je kozastupljenost mikotoksina u kontaminiranoj hrani veoma česta pojava. Faktori koji utiču na kolonizaciju plesni i sintezu mikotoksina odnose se na faktore spoljašnje sredine (ekstrinsik) u koje spadaju skladišni uslovi i koji se mogu kontrolisati, dok ostale faktore spoljašnje sredine kao što su klimatske promene ili unutrašnje (intrinsik) faktore, u koje spadaju specifičnost i varijacije pojedinih vrsta plesni i nestabilnost toksigenih svojstava plesni, je veoma teško kontrolisati. Mikotoksini u organizam ljudi i životinja najčešće dospevaju putem kontaminirane hrane, ali su inhalacioni i dermalni put, takođe mogući. Oboljenja ljudi i životinja izazvana mikotoksinima se nazivaju mikotoksikoze. Mikotoksini izazivaju različite akutne i hronične biološke efekte u organizmu ljudi i životinja. Smatra se da su monogastrične životinje daleko osetljivije na dejstvo mikotoksina u odnosu na preživare. Ekonomski značaj mikotoksina odražava se kroz povećane troškove lečenja ljudi i životinja, smanjenje produktivnih rezultata životinja uključujući i uginuća, direktne i indirektne štete koje nastaju usled uklanjanja kontaminirane hrane, investiranje u istraživanja i primenu preventivnih mera u sprečavanju negativnog efekta prisustva mikotoksina u hrani na zdravlje ljudi i životinja. Ovaj rad ima za cilj da sagleda ne samo zdravlje ljudi, već i da bude informativan za stručnjake u ovoj oblasti kako bi se otklonile određene nejasanoće vezane za prisustvo ove vrste hemijskog hazarda biološkog porekla u lancu ishrane. Stoga je u ovom radu prikazana zastupljenost i toksičnost najznačajnijih mikotoksina i način donošenja zakonske regulative. Takođe, opisane su analitičke metode za dokazivanje mikotoksina i mere koje se preduzimaju u prevenciji i kontroli mikotoksina.
PB  - Institut za higijenu i tehnologiju mesa, Beograd
T2  - Tehnologija mesa
T1  - Mycotoxins in food chain: Risk assessment and importance for public health
T1  - Mikotoksini u lancu ishrane - analiza rizika i značaj za javno zdravstvo
VL  - 55
IS  - 1
SP  - 22
EP  - 38
DO  - 10.5937/tehmesa1401022M
ER  - 

@article{
author = "Milićević, Dragan and Nedeljković-Trailović, Jelena and Mašić, Zoran",
year = "2014",
abstract = "Disease outbreaks due to the consumption of contaminated food and feedstuff are a recurring problem worldwide. The major factor contributing to contamination are microorganisms, especially fungi, which produce low-molecular-weight compounds as secondary metabolites, with confirmed toxic properties referred to as mycotoxins. Mycotoxins are toxic secondary metabolites produced by fungi that invade crops at the field level and may grow on foods during storage under favorable conditions. The toxigenic fungi of Aspergillus, Penicillium, Fusarium, Alternari and Clavicepshave genera are of the greatest consequence to food safety. Mycotoxins, of over 400 that are known, which have the most food safety, nutritive, ecologic and economic significance include the aflatoxins, ochratoxins, trichothecenes, zearalenone, fumonisins, tremorgenic mycotoxinsand ergotalcaloides. Some molds are capable of producing more than one mycotoxin and some mycotoxins are produced by more than one fungal species. Often more than one mycotoxin is found on a contaminated substrate. Factors influencing the presence of mycotoxins in foods or feeds include environmental conditions related to storage that can be controlled. Other extrinsic factors such as climate or intrinsic factors such as fungal strain specificity, strain variation, and instability of toxigenic properties are more difficult to control. Exposure to mycotoxins is mostly by ingestion, but also occurs by the dermal and inhalation routes. The diseases caused by exposure to mycotoxins are known as mycotoxicoses. Mycotoxins have various acute and chronic effects on humans and animals (especially monogastrics) depending on species and susceptibility of an animal within a species. Ruminants, however, are generally more resistant to the adverse effects of mycotoxins. This is because the rumen microbiota is capable of degrading mycotoxins. The economic impact of mycotoxins include loss of human and animal life, increased health care and veterinary care costs, reduced livestock production, disposal of contaminated foods and feeds, and investment in research and applications to reduce severity of the mycotoxin problem. This review is meant to be informative not only for health-conscious consumers but also for experts in the field to pave the way for future research to fill the existing gaps in our knowledge in regard to mycotoxins and food safety. In this review, the focus is on the occurrence of various types of mycotoxins in food and feed associated with risks to humans and livestock, as well as legislation put forth by various authorities. Brief descriptions on recent developments in mycotoxin detection methodology and on presently practiced detoxification methods are also included., Oboljenja ljudi prouzrokovana kontaminiranom hranom predstavljaju jedan od najvećih problema sa kojim se suočava savremeno čovečanstvo. Glavni uzročnici kontaminacije su mikroorganizmi, naročito plesni, koje sintetišu jedinjenja male molekulske mase sa izrazitim toksičnim efektom na žive organizme. Mikotoksini su sekundarni metaboliti pretežno Aspergillus, Penicillium, Fusarium, Alternaria i Claviceps vrsta plesni, koje mogu kontaminirati hranu na polju (preharvest) i/ili tokom skladištenja (postharvest). Iako je do sada poznato preko 400 mikotoksina zbog svoje zastupljenosti i toksičnosti, afl atoksini (AFT), ohratoksin A (OTA), trihoteceni (TCT), zearalenon (ZEA), fumonizini (FB), tremorgeni mikotoksini i ergotalkaloidi, predstavljaju najveći medicinski, nutritivni, ekološki i ekonomski problem. Specifičnost mikotoksina u odnosu na druge toksine ogleda se u tome da pojedini rodovi plesni mogu da sintetišu nekoliko mikotoksina, kao i to da pojedini mikotoksini mogu biti proizvod sekundarnog metabolizma nekoliko rodova i vrsta plesni. S toga je kozastupljenost mikotoksina u kontaminiranoj hrani veoma česta pojava. Faktori koji utiču na kolonizaciju plesni i sintezu mikotoksina odnose se na faktore spoljašnje sredine (ekstrinsik) u koje spadaju skladišni uslovi i koji se mogu kontrolisati, dok ostale faktore spoljašnje sredine kao što su klimatske promene ili unutrašnje (intrinsik) faktore, u koje spadaju specifičnost i varijacije pojedinih vrsta plesni i nestabilnost toksigenih svojstava plesni, je veoma teško kontrolisati. Mikotoksini u organizam ljudi i životinja najčešće dospevaju putem kontaminirane hrane, ali su inhalacioni i dermalni put, takođe mogući. Oboljenja ljudi i životinja izazvana mikotoksinima se nazivaju mikotoksikoze. Mikotoksini izazivaju različite akutne i hronične biološke efekte u organizmu ljudi i životinja. Smatra se da su monogastrične životinje daleko osetljivije na dejstvo mikotoksina u odnosu na preživare. Ekonomski značaj mikotoksina odražava se kroz povećane troškove lečenja ljudi i životinja, smanjenje produktivnih rezultata životinja uključujući i uginuća, direktne i indirektne štete koje nastaju usled uklanjanja kontaminirane hrane, investiranje u istraživanja i primenu preventivnih mera u sprečavanju negativnog efekta prisustva mikotoksina u hrani na zdravlje ljudi i životinja. Ovaj rad ima za cilj da sagleda ne samo zdravlje ljudi, već i da bude informativan za stručnjake u ovoj oblasti kako bi se otklonile određene nejasanoće vezane za prisustvo ove vrste hemijskog hazarda biološkog porekla u lancu ishrane. Stoga je u ovom radu prikazana zastupljenost i toksičnost najznačajnijih mikotoksina i način donošenja zakonske regulative. Takođe, opisane su analitičke metode za dokazivanje mikotoksina i mere koje se preduzimaju u prevenciji i kontroli mikotoksina.",
publisher = "Institut za higijenu i tehnologiju mesa, Beograd",
journal = "Tehnologija mesa",
title = "Mycotoxins in food chain: Risk assessment and importance for public health, Mikotoksini u lancu ishrane - analiza rizika i značaj za javno zdravstvo",
volume = "55",
number = "1",
pages = "22-38",
doi = "10.5937/tehmesa1401022M"
}

Milićević, D., Nedeljković-Trailović, J.,& Mašić, Z.. (2014). Mycotoxins in food chain: Risk assessment and importance for public health. in Tehnologija mesa
Institut za higijenu i tehnologiju mesa, Beograd., 55(1), 22-38.
https://doi.org/10.5937/tehmesa1401022M

Milićević D, Nedeljković-Trailović J, Mašić Z. Mycotoxins in food chain: Risk assessment and importance for public health. in Tehnologija mesa. 2014;55(1):22-38.
doi:10.5937/tehmesa1401022M .

Milićević, Dragan, Nedeljković-Trailović, Jelena, Mašić, Zoran, "Mycotoxins in food chain: Risk assessment and importance for public health" in Tehnologija mesa, 55, no. 1 (2014):22-38,
https://doi.org/10.5937/tehmesa1401022M . .

TY  - JOUR
AU  - Resanović, Radmila
AU  - Vučićević, Miloš
AU  - Nedeljković-Trailović, Jelena
AU  - Maslić-Strižak, Danka
AU  - Jaćević, Vesna
PY  - 2013
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/1017
AB  - Health risks associated with the consumption of products contaminated with mycotoxins are worldwide recognized and depend on the extent to which they are consumed in diversified diet. To some extent, the presence of small amount of mycotoxins in cereals and related food products is unavoidable; this requires risk assessments which are to be carried out by regulatory bodies in several countries to help establish regulatory guidelines for the protection of public health. By assessing the levels at which these substances in food may pose a potential risk to human health, it is possible to devise appropriate risk management strategies. However, several important factors have to be taken into account in making a rational risk management decision, such as adequate toxicological data and information concerning the extent of exposure, availability of technically sound analytical procedures (including sampling), socioeconomic factors, food intake patterns and levels of mycotoxins in food commodities which may vary considerably between countries.
AB  - Zdravstveni rizici povezani sa konzumacijom proizvoda kontaminiranih mikotoksinima su prepoznati u celom svetu. U izvesnoj meri prisustvo malih količina mikotoksina u žitaricama i drugim proizvodima je očekivano i neminovno. To iziskuje procenu rizika od strane regulatornih tela koja moraju imati ulogu u uspostavljanju regulatornih smernica za zaštitu javnog zdravlja. Nakon procene nivoa mikotoksina u hrani potrebno je osmisliti odgovarajuće strategije za upravljanje rizikom. Nekoliko važnih faktora treba uzeti u obzir pri donošenju odluka o racionalnom upravljanju rizikom, uključujući toksikološke podatke, nivoe izloženosti, dostupnost analitičkih procedura, socioekonomske faktore i nacionalnu legislativu.
PB  - Matica srpska, Novi Sad
T2  - Zbornik Matice srpske za prirodne nauke
T1  - Mycotoxins and their effect on human health
T1  - Mikotoksini i njihov efekat na ljudsko zdravlje
IS  - 124
SP  - 315
EP  - 324
DO  - 10.2298/ZMSPN1324315R
ER  - 

@article{
author = "Resanović, Radmila and Vučićević, Miloš and Nedeljković-Trailović, Jelena and Maslić-Strižak, Danka and Jaćević, Vesna",
year = "2013",
abstract = "Health risks associated with the consumption of products contaminated with mycotoxins are worldwide recognized and depend on the extent to which they are consumed in diversified diet. To some extent, the presence of small amount of mycotoxins in cereals and related food products is unavoidable; this requires risk assessments which are to be carried out by regulatory bodies in several countries to help establish regulatory guidelines for the protection of public health. By assessing the levels at which these substances in food may pose a potential risk to human health, it is possible to devise appropriate risk management strategies. However, several important factors have to be taken into account in making a rational risk management decision, such as adequate toxicological data and information concerning the extent of exposure, availability of technically sound analytical procedures (including sampling), socioeconomic factors, food intake patterns and levels of mycotoxins in food commodities which may vary considerably between countries., Zdravstveni rizici povezani sa konzumacijom proizvoda kontaminiranih mikotoksinima su prepoznati u celom svetu. U izvesnoj meri prisustvo malih količina mikotoksina u žitaricama i drugim proizvodima je očekivano i neminovno. To iziskuje procenu rizika od strane regulatornih tela koja moraju imati ulogu u uspostavljanju regulatornih smernica za zaštitu javnog zdravlja. Nakon procene nivoa mikotoksina u hrani potrebno je osmisliti odgovarajuće strategije za upravljanje rizikom. Nekoliko važnih faktora treba uzeti u obzir pri donošenju odluka o racionalnom upravljanju rizikom, uključujući toksikološke podatke, nivoe izloženosti, dostupnost analitičkih procedura, socioekonomske faktore i nacionalnu legislativu.",
publisher = "Matica srpska, Novi Sad",
journal = "Zbornik Matice srpske za prirodne nauke",
title = "Mycotoxins and their effect on human health, Mikotoksini i njihov efekat na ljudsko zdravlje",
number = "124",
pages = "315-324",
doi = "10.2298/ZMSPN1324315R"
}

Resanović, R., Vučićević, M., Nedeljković-Trailović, J., Maslić-Strižak, D.,& Jaćević, V.. (2013). Mycotoxins and their effect on human health. in Zbornik Matice srpske za prirodne nauke
Matica srpska, Novi Sad.(124), 315-324.
https://doi.org/10.2298/ZMSPN1324315R

Resanović R, Vučićević M, Nedeljković-Trailović J, Maslić-Strižak D, Jaćević V. Mycotoxins and their effect on human health. in Zbornik Matice srpske za prirodne nauke. 2013;(124):315-324.
doi:10.2298/ZMSPN1324315R .

Resanović, Radmila, Vučićević, Miloš, Nedeljković-Trailović, Jelena, Maslić-Strižak, Danka, Jaćević, Vesna, "Mycotoxins and their effect on human health" in Zbornik Matice srpske za prirodne nauke, no. 124 (2013):315-324,
https://doi.org/10.2298/ZMSPN1324315R . .

TY  - JOUR
AU  - Nedeljković-Trailović, Jelena
AU  - Trailović, Saša
AU  - Dimitrijević, Mirjana
AU  - Ilić, Vojislav
PY  - 2013
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/1024
AB  - The 42-day long study was performed on a total number of 48 Hybro broilers divided into four groups. After the pre-experimental period of 14 days, 3 experimental groups of broilers (n=12) were formed and fed diets that contained 0.5, 1.0 and 1.5 mg/kg ochratoxin A (OTA) during the next seven consecutive days. In the same period, the control group of broilers was fed a diet with no toxin added. After the period of toxin addition, blood samples were taken from 6 animals in each group. The remaining animals (n=6) from the control and experimental groups were fed diets without OTA until the 42nd day of the study, when the blood samples were taken again. The total level of blood serum proteins was affected by treatment with different doses of OTA, but a significant and dose dependent increase of albumins together with a decrease of γ-globulin fraction was established. A/G ratio (Albumine/Globuline) suggested that the globulins were the dominant protein fraction in the blood serum samples obtained from all the broilers included in this study. The concentrations of α- and β- globulin in the serum were within physiological limits, but the concentration of γ-globulins significantly decreased. It can be concluded that the increasing dietary OTA levels (0.5, 1.0 and 1.5 mg/kg) had dose-dependent cumulative effect on blood serum proteins status in broilers, and the effect lasts even after the withdrawal of OTA from the feed.
AB  - Ispitivanje je trajalo 42 dan na ukupno 48 brojlera podeljenih u četiri jednake grupe. Preeksperimentalni period trajao je 14 dana, nakon čega su životinje tri ogledne grupe tokom sedam dana hranjene obrocma koji su sadržali 0,5, 1,0 i 1,5 mg ohratoksina A (OTA) u 1kg hrane. Brojleri kontrolne grupe u toku eksperimentalnog perioda hranjeni su hranom bez dodatka toksina. Posle sedam dana tretmana uzimani su uzorci krvi od po šest životinja iz svake grupe (kontrolne i eksperimentalnih). Preostale životinje hranjene su obrocima bez toksina do 42. dana ogleda, nakon čega je krv uzorkovana i od njih. Koncentracija ukupnih proteina plazme bila je promenjena u zavisnosti od koncentracije OTA koji su brojleri dobijali hranom. Takođe je zabeleženo značajno i dozno-zavisno povećanje koncentracije albumina sa snižavanjem koncentracije gama-globulinske frakcije u serumu. Albulin/Globulin odnos (A/G odnos) ukazuje da su globulini bili dominantna frakcija proteina kod svih brojlera u ispitivanju. Koncentracija alfa i beta-globulina u serumu brojlera kretala se u fiziološkim granicama dok je koncentracija gamaglobulina bila značajno snižena. Može se zaključiti da rastuće koncentracije OTA u hrani brojlera ispoljavaju dozno-zavistan kumulativni efekt na status serumskih proteina. Ovaj efekat ostaje i posle prestanka dodavanja toksina u hranu.
PB  - Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd
T2  - Acta Veterinaria-Beograd
T1  - Blood serum protein status in broilers fed with increasing concentrations of ochratoxin A
T1  - Status serumskih proteina brojlera hranjenih obrocima sa rastućim koncentracijama ohratoksina A
VL  - 63
IS  - 1
SP  - 77
EP  - 88
DO  - 10.2298/AVB1301077N
ER  - 

@article{
author = "Nedeljković-Trailović, Jelena and Trailović, Saša and Dimitrijević, Mirjana and Ilić, Vojislav",
year = "2013",
abstract = "The 42-day long study was performed on a total number of 48 Hybro broilers divided into four groups. After the pre-experimental period of 14 days, 3 experimental groups of broilers (n=12) were formed and fed diets that contained 0.5, 1.0 and 1.5 mg/kg ochratoxin A (OTA) during the next seven consecutive days. In the same period, the control group of broilers was fed a diet with no toxin added. After the period of toxin addition, blood samples were taken from 6 animals in each group. The remaining animals (n=6) from the control and experimental groups were fed diets without OTA until the 42nd day of the study, when the blood samples were taken again. The total level of blood serum proteins was affected by treatment with different doses of OTA, but a significant and dose dependent increase of albumins together with a decrease of γ-globulin fraction was established. A/G ratio (Albumine/Globuline) suggested that the globulins were the dominant protein fraction in the blood serum samples obtained from all the broilers included in this study. The concentrations of α- and β- globulin in the serum were within physiological limits, but the concentration of γ-globulins significantly decreased. It can be concluded that the increasing dietary OTA levels (0.5, 1.0 and 1.5 mg/kg) had dose-dependent cumulative effect on blood serum proteins status in broilers, and the effect lasts even after the withdrawal of OTA from the feed., Ispitivanje je trajalo 42 dan na ukupno 48 brojlera podeljenih u četiri jednake grupe. Preeksperimentalni period trajao je 14 dana, nakon čega su životinje tri ogledne grupe tokom sedam dana hranjene obrocma koji su sadržali 0,5, 1,0 i 1,5 mg ohratoksina A (OTA) u 1kg hrane. Brojleri kontrolne grupe u toku eksperimentalnog perioda hranjeni su hranom bez dodatka toksina. Posle sedam dana tretmana uzimani su uzorci krvi od po šest životinja iz svake grupe (kontrolne i eksperimentalnih). Preostale životinje hranjene su obrocima bez toksina do 42. dana ogleda, nakon čega je krv uzorkovana i od njih. Koncentracija ukupnih proteina plazme bila je promenjena u zavisnosti od koncentracije OTA koji su brojleri dobijali hranom. Takođe je zabeleženo značajno i dozno-zavisno povećanje koncentracije albumina sa snižavanjem koncentracije gama-globulinske frakcije u serumu. Albulin/Globulin odnos (A/G odnos) ukazuje da su globulini bili dominantna frakcija proteina kod svih brojlera u ispitivanju. Koncentracija alfa i beta-globulina u serumu brojlera kretala se u fiziološkim granicama dok je koncentracija gamaglobulina bila značajno snižena. Može se zaključiti da rastuće koncentracije OTA u hrani brojlera ispoljavaju dozno-zavistan kumulativni efekt na status serumskih proteina. Ovaj efekat ostaje i posle prestanka dodavanja toksina u hranu.",
publisher = "Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd",
journal = "Acta Veterinaria-Beograd",
title = "Blood serum protein status in broilers fed with increasing concentrations of ochratoxin A, Status serumskih proteina brojlera hranjenih obrocima sa rastućim koncentracijama ohratoksina A",
volume = "63",
number = "1",
pages = "77-88",
doi = "10.2298/AVB1301077N"
}

Nedeljković-Trailović, J., Trailović, S., Dimitrijević, M.,& Ilić, V.. (2013). Blood serum protein status in broilers fed with increasing concentrations of ochratoxin A. in Acta Veterinaria-Beograd
Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd., 63(1), 77-88.
https://doi.org/10.2298/AVB1301077N

Nedeljković-Trailović J, Trailović S, Dimitrijević M, Ilić V. Blood serum protein status in broilers fed with increasing concentrations of ochratoxin A. in Acta Veterinaria-Beograd. 2013;63(1):77-88.
doi:10.2298/AVB1301077N .

Nedeljković-Trailović, Jelena, Trailović, Saša, Dimitrijević, Mirjana, Ilić, Vojislav, "Blood serum protein status in broilers fed with increasing concentrations of ochratoxin A" in Acta Veterinaria-Beograd, 63, no. 1 (2013):77-88,
https://doi.org/10.2298/AVB1301077N . .

TY  - CONF
AU  - Petrujkić, Branko
AU  - Šefer, Dragan
AU  - Nedeljković Trailović, Jelena
AU  - Marković, Radmila
AU  - Dimitrijević, Vladimir
PY  - 2012
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/3845
PB  - Požarevac : Veterinarski specijalistički institut
C3  - 10. savetovanje sa međunarodnim učešćem Zdravstvena zaštita, selekcija i reprodukcija svinja, Srebrno jezero, 31. maj - 2. jun, 2012
T1  - Fumonizini u hrani za svinje - predisponirajući faktor za nastanak respiratornih oboljenja
SP  - 38
EP  - 41
UR  - https://hdl.handle.net/21.15107/rcub_veterinar_3845
ER  - 

@conference{
author = "Petrujkić, Branko and Šefer, Dragan and Nedeljković Trailović, Jelena and Marković, Radmila and Dimitrijević, Vladimir",
year = "2012",
publisher = "Požarevac : Veterinarski specijalistički institut",
journal = "10. savetovanje sa međunarodnim učešćem Zdravstvena zaštita, selekcija i reprodukcija svinja, Srebrno jezero, 31. maj - 2. jun, 2012",
title = "Fumonizini u hrani za svinje - predisponirajući faktor za nastanak respiratornih oboljenja",
pages = "38-41",
url = "https://hdl.handle.net/21.15107/rcub_veterinar_3845"
}

Petrujkić, B., Šefer, D., Nedeljković Trailović, J., Marković, R.,& Dimitrijević, V.. (2012). Fumonizini u hrani za svinje - predisponirajući faktor za nastanak respiratornih oboljenja. in 10. savetovanje sa međunarodnim učešćem Zdravstvena zaštita, selekcija i reprodukcija svinja, Srebrno jezero, 31. maj - 2. jun, 2012
Požarevac : Veterinarski specijalistički institut., 38-41.
https://hdl.handle.net/21.15107/rcub_veterinar_3845

Petrujkić B, Šefer D, Nedeljković Trailović J, Marković R, Dimitrijević V. Fumonizini u hrani za svinje - predisponirajući faktor za nastanak respiratornih oboljenja. in 10. savetovanje sa međunarodnim učešćem Zdravstvena zaštita, selekcija i reprodukcija svinja, Srebrno jezero, 31. maj - 2. jun, 2012. 2012;:38-41.
https://hdl.handle.net/21.15107/rcub_veterinar_3845 .

Petrujkić, Branko, Šefer, Dragan, Nedeljković Trailović, Jelena, Marković, Radmila, Dimitrijević, Vladimir, "Fumonizini u hrani za svinje - predisponirajući faktor za nastanak respiratornih oboljenja" in 10. savetovanje sa međunarodnim učešćem Zdravstvena zaštita, selekcija i reprodukcija svinja, Srebrno jezero, 31. maj - 2. jun, 2012 (2012):38-41,
https://hdl.handle.net/21.15107/rcub_veterinar_3845 .

TY  - JOUR
AU  - Vučinić, Marijana
AU  - Nedeljković-Trailović, Jelena
AU  - Trailović, Saša
AU  - Ivanović, Saša
AU  - Milovanović, Mirjana
AU  - Krnjaić, Dejan
PY  - 2012
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/883
AB  - The paper reviews the latest studies on possible applications of oregano essential oil in veterinary medicine and animal livestock production. The first part of the paper deals with the definition of essential oils, possibilities for their extraction from plants, possibilities for their application in human and veterinary medicine, the interest of a science in essential oils, and, essential oils classification based on their use in human and veterinary medicine. The second part of the review deals with the properties of oregano essential oil, its main active principles, carvacrol and thymol and its application in veterinary medicine and animal livestock production. Oregano essential oil may be applied in animal feed, in the treatment of coccidiosis of domestic animals and candidiasis. It can be applied as a larvicide, repellent, insecticide and acaricide. It is used in aquaculture to treat fish diseases caused by bacteria and parasites or in the hatchery industry as a disinfectant for eggs or for disinfection of manure. The greatest potential of oregano essential oil is the possibility of its application in organic agriculture and organic animal husbandry.
AB  - U radu su izložena novija saznanja o mogućnosti primene etarskog ulja origana u veterinarskoj medicini i stočarstvu. U prvom delu rada izneta je definicija i način dobijanja etarskih ulja, mogućnosti primene etarskih ulja, zainteresovanost nauke za etarska ulja, klasifikacija etarskih ulja na osnovu njihove primene u humanoj i veterinarskoj medicini. Drugi deo rada se odnosi na osobine etarskog ulja origana, njegove osnovne aktivne sastojke, karvakrol i timol, i mogućnost primene u veterinarskoj medicini i stočarstvu. Ulje origanaima široku mogućnost primene u ishrani domaćih životinja, u lečenju kokcidioze i kandidijaze domaćih životinja. Može da se primeni kao larvicid, repelent, insekticid i akaricid. Koristi se i u akvakulturi za lečenje bolesti riba prouzrokovanih bakterijama i parazitima, za dezinfekciju jaja i za dezinfekciju stajnjaka. Najveći potencijal etarskog ulja origana je mogućnost njegove primene u organskoj poljoprivredi i organskom stočarstvu.
PB  - Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd
T2  - Veterinarski Glasnik
T1  - Possibility for use essential oils in veterinary medicine and animal husbandry with special emphasis on oregano oil
T1  - Mogućnost primene etarskih ulja u veterinarskoj medicini i stočarstvu s posebnim osvrtom na etarsko ulje origana
VL  - 66
IS  - 5-6
SP  - 407
EP  - 416
DO  - 10.2298/VETGL1206407V
ER  - 

@article{
author = "Vučinić, Marijana and Nedeljković-Trailović, Jelena and Trailović, Saša and Ivanović, Saša and Milovanović, Mirjana and Krnjaić, Dejan",
year = "2012",
abstract = "The paper reviews the latest studies on possible applications of oregano essential oil in veterinary medicine and animal livestock production. The first part of the paper deals with the definition of essential oils, possibilities for their extraction from plants, possibilities for their application in human and veterinary medicine, the interest of a science in essential oils, and, essential oils classification based on their use in human and veterinary medicine. The second part of the review deals with the properties of oregano essential oil, its main active principles, carvacrol and thymol and its application in veterinary medicine and animal livestock production. Oregano essential oil may be applied in animal feed, in the treatment of coccidiosis of domestic animals and candidiasis. It can be applied as a larvicide, repellent, insecticide and acaricide. It is used in aquaculture to treat fish diseases caused by bacteria and parasites or in the hatchery industry as a disinfectant for eggs or for disinfection of manure. The greatest potential of oregano essential oil is the possibility of its application in organic agriculture and organic animal husbandry., U radu su izložena novija saznanja o mogućnosti primene etarskog ulja origana u veterinarskoj medicini i stočarstvu. U prvom delu rada izneta je definicija i način dobijanja etarskih ulja, mogućnosti primene etarskih ulja, zainteresovanost nauke za etarska ulja, klasifikacija etarskih ulja na osnovu njihove primene u humanoj i veterinarskoj medicini. Drugi deo rada se odnosi na osobine etarskog ulja origana, njegove osnovne aktivne sastojke, karvakrol i timol, i mogućnost primene u veterinarskoj medicini i stočarstvu. Ulje origanaima široku mogućnost primene u ishrani domaćih životinja, u lečenju kokcidioze i kandidijaze domaćih životinja. Može da se primeni kao larvicid, repelent, insekticid i akaricid. Koristi se i u akvakulturi za lečenje bolesti riba prouzrokovanih bakterijama i parazitima, za dezinfekciju jaja i za dezinfekciju stajnjaka. Najveći potencijal etarskog ulja origana je mogućnost njegove primene u organskoj poljoprivredi i organskom stočarstvu.",
publisher = "Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd",
journal = "Veterinarski Glasnik",
title = "Possibility for use essential oils in veterinary medicine and animal husbandry with special emphasis on oregano oil, Mogućnost primene etarskih ulja u veterinarskoj medicini i stočarstvu s posebnim osvrtom na etarsko ulje origana",
volume = "66",
number = "5-6",
pages = "407-416",
doi = "10.2298/VETGL1206407V"
}

Vučinić, M., Nedeljković-Trailović, J., Trailović, S., Ivanović, S., Milovanović, M.,& Krnjaić, D.. (2012). Possibility for use essential oils in veterinary medicine and animal husbandry with special emphasis on oregano oil. in Veterinarski Glasnik
Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd., 66(5-6), 407-416.
https://doi.org/10.2298/VETGL1206407V

Vučinić M, Nedeljković-Trailović J, Trailović S, Ivanović S, Milovanović M, Krnjaić D. Possibility for use essential oils in veterinary medicine and animal husbandry with special emphasis on oregano oil. in Veterinarski Glasnik. 2012;66(5-6):407-416.
doi:10.2298/VETGL1206407V .

Vučinić, Marijana, Nedeljković-Trailović, Jelena, Trailović, Saša, Ivanović, Saša, Milovanović, Mirjana, Krnjaić, Dejan, "Possibility for use essential oils in veterinary medicine and animal husbandry with special emphasis on oregano oil" in Veterinarski Glasnik, 66, no. 5-6 (2012):407-416,
https://doi.org/10.2298/VETGL1206407V . .

TY  - JOUR
AU  - Vučinić, Marijana
AU  - Nedeljković-Trailović, Jelena
AU  - Trailović, Saša
AU  - Ivanović, Saša
AU  - Milovanović, Mirjana
AU  - Krnjaić, Dejan
PY  - 2012
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/2093
AB  - У овом раду су описане могућности примене карвакрола и есенцијалних уља
богатих карвакролом у рибарству. Карвакрол је активни састојак есенцијалних
уља многих биљних врста са антимикробним особинама. Управо зато и може да
се користи у третману многих болести риба, као фитоадитив и у конзервисању
јестивих производа од риба. Литературни подаци указују да су карвакрол и
есенцијална уља богата карвакролом ефикасни у односу на многе узрочнике
болести риба. Такође, карвакрол може да се користи и као анестетик за рибе.
Есенцијална уља богата карвакролом могу да се користе као анестетици, који
задовољавају критеријуме сигурности и безбедности јестивих производа од
риба, еколошке критеријуме, као и ефикасности широког спектра деловања на
различите врсте риба. Новији подаци указују да есенцијална уља богата
садржајем карвакрола или смеша карвакрола и тимола делују као имуно-
модулатори и имуностимулатори код риба. Такође делују и као биопродуктиви
и антиоксиданси. Есенцијална уља богата карвакролом могу да се користе и као
биопрезарвативи, односно за спречавање квара јестивих производа од риба.
AB  - The paper deals with possibilities of carvacrol and carvacrol rich essential oils
use in fishery. Carvacrol is an active ingredient of many essential oils with
antimicrobial properties. Therefore, it may be used in treatment of many fish
diseases, as a phytoadditive, as well as, in preservation of edible fish products.
Literature data point to carvacrol and carvacrol rich essential oils may be effective
against different causal agents of fish diseases. Also, carvacrol acts as anesthetic
for fish. Carvacrol rich essential oils may be very promising anesthetic agent in
terms of safety of edible fish products, environmental friendliness and efficacy in
various fish species. Recent data sugest that carvacrol rich essential oils or
combination of carvacrol and thymol act as immunomodulators and
immunostimulants in fish. Also they act as bioproductives and antioxidants.
Carvacrol rich essential oils may be used as biopreservatives for edible fish
products.
PB  - Banja Luka : PI Veterinary Institute Republic of Srpska „Dr. Vaso Butozan“
T2  - Veterinarski žurnal Republike Srpske
T1  - Mogućnost primene karvakrola i esencijalnih ulja bogatih karvakrolom u ribarstvu
T1  - Possibilities of carvacrol and carvacrol rich essential oils applying in fishery
VL  - 12
IS  - 2
SP  - 97
EP  - 103
UR  - https://hdl.handle.net/21.15107/rcub_veterinar_2093
ER  - 

@article{
author = "Vučinić, Marijana and Nedeljković-Trailović, Jelena and Trailović, Saša and Ivanović, Saša and Milovanović, Mirjana and Krnjaić, Dejan",
year = "2012",
abstract = "У овом раду су описане могућности примене карвакрола и есенцијалних уља
богатих карвакролом у рибарству. Карвакрол је активни састојак есенцијалних
уља многих биљних врста са антимикробним особинама. Управо зато и може да
се користи у третману многих болести риба, као фитоадитив и у конзервисању
јестивих производа од риба. Литературни подаци указују да су карвакрол и
есенцијална уља богата карвакролом ефикасни у односу на многе узрочнике
болести риба. Такође, карвакрол може да се користи и као анестетик за рибе.
Есенцијална уља богата карвакролом могу да се користе као анестетици, који
задовољавају критеријуме сигурности и безбедности јестивих производа од
риба, еколошке критеријуме, као и ефикасности широког спектра деловања на
различите врсте риба. Новији подаци указују да есенцијална уља богата
садржајем карвакрола или смеша карвакрола и тимола делују као имуно-
модулатори и имуностимулатори код риба. Такође делују и као биопродуктиви
и антиоксиданси. Есенцијална уља богата карвакролом могу да се користе и као
биопрезарвативи, односно за спречавање квара јестивих производа од риба., The paper deals with possibilities of carvacrol and carvacrol rich essential oils
use in fishery. Carvacrol is an active ingredient of many essential oils with
antimicrobial properties. Therefore, it may be used in treatment of many fish
diseases, as a phytoadditive, as well as, in preservation of edible fish products.
Literature data point to carvacrol and carvacrol rich essential oils may be effective
against different causal agents of fish diseases. Also, carvacrol acts as anesthetic
for fish. Carvacrol rich essential oils may be very promising anesthetic agent in
terms of safety of edible fish products, environmental friendliness and efficacy in
various fish species. Recent data sugest that carvacrol rich essential oils or
combination of carvacrol and thymol act as immunomodulators and
immunostimulants in fish. Also they act as bioproductives and antioxidants.
Carvacrol rich essential oils may be used as biopreservatives for edible fish
products.",
publisher = "Banja Luka : PI Veterinary Institute Republic of Srpska „Dr. Vaso Butozan“",
journal = "Veterinarski žurnal Republike Srpske",
title = "Mogućnost primene karvakrola i esencijalnih ulja bogatih karvakrolom u ribarstvu, Possibilities of carvacrol and carvacrol rich essential oils applying in fishery",
volume = "12",
number = "2",
pages = "97-103",
url = "https://hdl.handle.net/21.15107/rcub_veterinar_2093"
}

Vučinić, M., Nedeljković-Trailović, J., Trailović, S., Ivanović, S., Milovanović, M.,& Krnjaić, D.. (2012). Mogućnost primene karvakrola i esencijalnih ulja bogatih karvakrolom u ribarstvu. in Veterinarski žurnal Republike Srpske
Banja Luka : PI Veterinary Institute Republic of Srpska „Dr. Vaso Butozan“., 12(2), 97-103.
https://hdl.handle.net/21.15107/rcub_veterinar_2093

Vučinić M, Nedeljković-Trailović J, Trailović S, Ivanović S, Milovanović M, Krnjaić D. Mogućnost primene karvakrola i esencijalnih ulja bogatih karvakrolom u ribarstvu. in Veterinarski žurnal Republike Srpske. 2012;12(2):97-103.
https://hdl.handle.net/21.15107/rcub_veterinar_2093 .

Vučinić, Marijana, Nedeljković-Trailović, Jelena, Trailović, Saša, Ivanović, Saša, Milovanović, Mirjana, Krnjaić, Dejan, "Mogućnost primene karvakrola i esencijalnih ulja bogatih karvakrolom u ribarstvu" in Veterinarski žurnal Republike Srpske, 12, no. 2 (2012):97-103,
https://hdl.handle.net/21.15107/rcub_veterinar_2093 .