TY  - CONF
AU  - Stepanović, Predrag
AU  - Lazarević Macanović, Mirjana
AU  - Karić, Lazar
AU  - Tojić, Aleksa
AU  - Krstić, Nikola
PY  - 2024
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/3707
AB  - Upotreba rendgenskih i ultrazvučnih aparata je sve više zastupljena
u dijagnostici patoloških stanja respiratornog i kardiovaskularnog
sistema malih životinja. U slučajevima torakalne traume, kašlja,
stridora, disanja na usta i regurgitacije hrane, kao i pojave groznice,
dispnoje, tahipnoje i cijanoze sluznica, indikovano je sprovođene rendgenske
i/ili ehokardiografske dijagnostike. Ove metode su komplementarne
i uz rezultate kliničkog i laboratorijskog pregleda, pružaju
dovoljno podataka za postavljanje validne dijagnoze. Zbog svoje neinvazivnosti
i relativno brzog i jednostavnog izvođenja, moguće ih je
višekratno ponavljati, što omogućava praćenje napredovanja bolesti i
procenjivanje efekata primenjene terapije.
U okviru ove radionice, polaznici će se upoznati sa tehnikama
rendgenskog snimanja toraksa i ehokardiografskog pregleda. Detaljno
će biti opisana anatomija respiratornih organa i srca u rendgenskoj,
odnosno ultrazvučnoj slici. Pored toga, biće prikazana i brojna patološka
stanja koja se na ovim organima sreću u svakodnevnoj kliničkoj
praksi.
PB  - Beograd : Fakultet veterinarske medicine, Centar za izdavačku delatnost i promet učila
C3  - XLV Seminar za inovacije znanja veterinara, Beograd, 23. februar 2024
T1  - Torakalna radiografija i ehokardiografija pasa sa kardiorespiratornim i digestivnim poremećajima
SP  - 149
EP  - 159
UR  - https://hdl.handle.net/21.15107/rcub_veterinar_3707
ER  - 

@conference{
author = "Stepanović, Predrag and Lazarević Macanović, Mirjana and Karić, Lazar and Tojić, Aleksa and Krstić, Nikola",
year = "2024",
abstract = "Upotreba rendgenskih i ultrazvučnih aparata je sve više zastupljena
u dijagnostici patoloških stanja respiratornog i kardiovaskularnog
sistema malih životinja. U slučajevima torakalne traume, kašlja,
stridora, disanja na usta i regurgitacije hrane, kao i pojave groznice,
dispnoje, tahipnoje i cijanoze sluznica, indikovano je sprovođene rendgenske
i/ili ehokardiografske dijagnostike. Ove metode su komplementarne
i uz rezultate kliničkog i laboratorijskog pregleda, pružaju
dovoljno podataka za postavljanje validne dijagnoze. Zbog svoje neinvazivnosti
i relativno brzog i jednostavnog izvođenja, moguće ih je
višekratno ponavljati, što omogućava praćenje napredovanja bolesti i
procenjivanje efekata primenjene terapije.
U okviru ove radionice, polaznici će se upoznati sa tehnikama
rendgenskog snimanja toraksa i ehokardiografskog pregleda. Detaljno
će biti opisana anatomija respiratornih organa i srca u rendgenskoj,
odnosno ultrazvučnoj slici. Pored toga, biće prikazana i brojna patološka
stanja koja se na ovim organima sreću u svakodnevnoj kliničkoj
praksi.",
publisher = "Beograd : Fakultet veterinarske medicine, Centar za izdavačku delatnost i promet učila",
journal = "XLV Seminar za inovacije znanja veterinara, Beograd, 23. februar 2024",
title = "Torakalna radiografija i ehokardiografija pasa sa kardiorespiratornim i digestivnim poremećajima",
pages = "149-159",
url = "https://hdl.handle.net/21.15107/rcub_veterinar_3707"
}

Stepanović, P., Lazarević Macanović, M., Karić, L., Tojić, A.,& Krstić, N.. (2024). Torakalna radiografija i ehokardiografija pasa sa kardiorespiratornim i digestivnim poremećajima. in XLV Seminar za inovacije znanja veterinara, Beograd, 23. februar 2024
Beograd : Fakultet veterinarske medicine, Centar za izdavačku delatnost i promet učila., 149-159.
https://hdl.handle.net/21.15107/rcub_veterinar_3707

Stepanović P, Lazarević Macanović M, Karić L, Tojić A, Krstić N. Torakalna radiografija i ehokardiografija pasa sa kardiorespiratornim i digestivnim poremećajima. in XLV Seminar za inovacije znanja veterinara, Beograd, 23. februar 2024. 2024;:149-159.
https://hdl.handle.net/21.15107/rcub_veterinar_3707 .

Stepanović, Predrag, Lazarević Macanović, Mirjana, Karić, Lazar, Tojić, Aleksa, Krstić, Nikola, "Torakalna radiografija i ehokardiografija pasa sa kardiorespiratornim i digestivnim poremećajima" in XLV Seminar za inovacije znanja veterinara, Beograd, 23. februar 2024 (2024):149-159,
https://hdl.handle.net/21.15107/rcub_veterinar_3707 .

TY  - JOUR
AU  - Todorović, Anastasija Z.
AU  - Krstić, Nikola E.
AU  - Žikić, Dragan R.
AU  - Van Bree, Henri JJ.
AU  - Mlv. Gielen, Ingrid
AU  - Lazarević Macanović, Mirjana
PY  - 2024
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/3761
AB  - The aim of this study was to establish two new methods for measuring the tibial plateau
angle (TPA): proximal tibial circle (PTC) as well as full tibial circle (FTC) method, and
to test their reliability in comparison to the classical method (CM). Three radiologists
implemented each method, and measurements were repeated three times.
The results of consecutive measurements obtained by two observers had excellent
reliability with an interclass correlation coefficient (ICC) greater than 0.9 for all
methods, while measurements obtained by the third observer had good reliability for
the CM (ICC=0.885) and PTC method (ICC=0.851).
The results obtained by the three observers for all methods indicate good reliability for
the PTC and FTC methods (ICC=0.848 and 0.880, respectively) and excellent reliability
for CM (ICC = 0.909); the results of the different observers for each method were not
significantly different.
The significant difference resulting from the applied measurement method (ICC =
0.447 and P<0.01) was confirmed. Statistically significant differences were not found
between the CM and PTC method (P>0.05), while differences between the PTC and
FTC, as well as CM and FTC methods, were statistically significant (P<0.01).
New methods for TPA measurements based on shorter tibial axes may be an alternative
to a method based on the full-length axis. A high correlation between the methods
indicates the precision of each of them. Newly established methods can be used when
the tarsal joint is not included in radiographs or is affected by degenerative changes,
making use of the classical method not possible.
PB  - Beograd : Fakultet veterinarske medicine
T2  - Acta Veterinaria
T1  - Tibial plateau angle measuremet in dogs – comparison of three different methods
VL  - 74
IS  - 1
SP  - 17
EP  - 29
DO  - 10.2478/acve-2024-0002
ER  - 

@article{
author = "Todorović, Anastasija Z. and Krstić, Nikola E. and Žikić, Dragan R. and Van Bree, Henri JJ. and Mlv. Gielen, Ingrid and Lazarević Macanović, Mirjana",
year = "2024",
abstract = "The aim of this study was to establish two new methods for measuring the tibial plateau
angle (TPA): proximal tibial circle (PTC) as well as full tibial circle (FTC) method, and
to test their reliability in comparison to the classical method (CM). Three radiologists
implemented each method, and measurements were repeated three times.
The results of consecutive measurements obtained by two observers had excellent
reliability with an interclass correlation coefficient (ICC) greater than 0.9 for all
methods, while measurements obtained by the third observer had good reliability for
the CM (ICC=0.885) and PTC method (ICC=0.851).
The results obtained by the three observers for all methods indicate good reliability for
the PTC and FTC methods (ICC=0.848 and 0.880, respectively) and excellent reliability
for CM (ICC = 0.909); the results of the different observers for each method were not
significantly different.
The significant difference resulting from the applied measurement method (ICC =
0.447 and P<0.01) was confirmed. Statistically significant differences were not found
between the CM and PTC method (P>0.05), while differences between the PTC and
FTC, as well as CM and FTC methods, were statistically significant (P<0.01).
New methods for TPA measurements based on shorter tibial axes may be an alternative
to a method based on the full-length axis. A high correlation between the methods
indicates the precision of each of them. Newly established methods can be used when
the tarsal joint is not included in radiographs or is affected by degenerative changes,
making use of the classical method not possible.",
publisher = "Beograd : Fakultet veterinarske medicine",
journal = "Acta Veterinaria",
title = "Tibial plateau angle measuremet in dogs – comparison of three different methods",
volume = "74",
number = "1",
pages = "17-29",
doi = "10.2478/acve-2024-0002"
}

Todorović, A. Z., Krstić, N. E., Žikić, D. R., Van Bree, H. JJ., Mlv. Gielen, I.,& Lazarević Macanović, M.. (2024). Tibial plateau angle measuremet in dogs – comparison of three different methods. in Acta Veterinaria
Beograd : Fakultet veterinarske medicine., 74(1), 17-29.
https://doi.org/10.2478/acve-2024-0002

Todorović AZ, Krstić NE, Žikić DR, Van Bree HJ, Mlv. Gielen I, Lazarević Macanović M. Tibial plateau angle measuremet in dogs – comparison of three different methods. in Acta Veterinaria. 2024;74(1):17-29.
doi:10.2478/acve-2024-0002 .

Todorović, Anastasija Z., Krstić, Nikola E., Žikić, Dragan R., Van Bree, Henri JJ., Mlv. Gielen, Ingrid, Lazarević Macanović, Mirjana, "Tibial plateau angle measuremet in dogs – comparison of three different methods" in Acta Veterinaria, 74, no. 1 (2024):17-29,
https://doi.org/10.2478/acve-2024-0002 . .

TY  - JOUR
AU  - Mitrović, Marko Jumake
AU  - Todorović, Anastasija
AU  - Krstić, Nikola
AU  - Vrbanac, Zoran
AU  - Janevski, Aleksandar
AU  - Lazarević Macanović, Mirjana
PY  - 2023
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/2731
AB  - Patološka su stanja zuba kunića u svakodnevnoj kliničkoj praksi vrlo česta i često rezultiraju poremećajem u funkciji organa probavnog i respiratornog sustava, a mogu imati i letalan ishod. Da bi se omogućila pravovremena primjena terapije i spriječila pojava komplikacija, posebnu pažnju treba usmjeriti na ranu dijagnostiku. Radiološka dijagnostika predstavlja jednostavan, brz i nezaobilazan postupak u procjeni stanja zubi. Za razliku od drugih vrsta sisavaca, radiološki pregled zuba kunića se odlikuje određenim osobitostima koje se, prije svega, očituju u tehnikama snimanja i interpretaciji rendgenskih snimaka koji su detaljno prikazani u ovom radu.
AB  - Pathological conditions of rabbit teeth are very common in daily clinical practice and often result in dysfunction of the organs belonging to the digestive and respiratory systems, with a possible fatal outcome. Therefore, special attention should be devoted to early diagnostics to enable timely treatment and prevent complications. Radiological diagnostics is a simple, fast and unavoidable procedure in the assessment of dental conditions. However, unlike other mammal species, radiological examination of rabbit teeth is characterised by certain specificities in examination techniques and radiograph interpretation, presented in detail in this paper
PB  - Zagreb : Croatian Veterinary Institute
T2  - Veterinarska Stanica
T1  - Radiološki pregled zuba  kunića – tehnike pregleda i  interpretacija snimki
VL  - 54
IS  - 5
SP  - 581
EP  - 589
DO  - https://doi.org/10.46419/vs.54.5.5
ER  - 

@article{
author = "Mitrović, Marko Jumake and Todorović, Anastasija and Krstić, Nikola and Vrbanac, Zoran and Janevski, Aleksandar and Lazarević Macanović, Mirjana",
year = "2023",
abstract = "Patološka su stanja zuba kunića u svakodnevnoj kliničkoj praksi vrlo česta i često rezultiraju poremećajem u funkciji organa probavnog i respiratornog sustava, a mogu imati i letalan ishod. Da bi se omogućila pravovremena primjena terapije i spriječila pojava komplikacija, posebnu pažnju treba usmjeriti na ranu dijagnostiku. Radiološka dijagnostika predstavlja jednostavan, brz i nezaobilazan postupak u procjeni stanja zubi. Za razliku od drugih vrsta sisavaca, radiološki pregled zuba kunića se odlikuje određenim osobitostima koje se, prije svega, očituju u tehnikama snimanja i interpretaciji rendgenskih snimaka koji su detaljno prikazani u ovom radu., Pathological conditions of rabbit teeth are very common in daily clinical practice and often result in dysfunction of the organs belonging to the digestive and respiratory systems, with a possible fatal outcome. Therefore, special attention should be devoted to early diagnostics to enable timely treatment and prevent complications. Radiological diagnostics is a simple, fast and unavoidable procedure in the assessment of dental conditions. However, unlike other mammal species, radiological examination of rabbit teeth is characterised by certain specificities in examination techniques and radiograph interpretation, presented in detail in this paper",
publisher = "Zagreb : Croatian Veterinary Institute",
journal = "Veterinarska Stanica",
title = "Radiološki pregled zuba  kunića – tehnike pregleda i  interpretacija snimki",
volume = "54",
number = "5",
pages = "581-589",
doi = "https://doi.org/10.46419/vs.54.5.5"
}

Mitrović, M. J., Todorović, A., Krstić, N., Vrbanac, Z., Janevski, A.,& Lazarević Macanović, M.. (2023). Radiološki pregled zuba  kunića – tehnike pregleda i  interpretacija snimki. in Veterinarska Stanica
Zagreb : Croatian Veterinary Institute., 54(5), 581-589.
https://doi.org/https://doi.org/10.46419/vs.54.5.5

Mitrović MJ, Todorović A, Krstić N, Vrbanac Z, Janevski A, Lazarević Macanović M. Radiološki pregled zuba  kunića – tehnike pregleda i  interpretacija snimki. in Veterinarska Stanica. 2023;54(5):581-589.
doi:https://doi.org/10.46419/vs.54.5.5 .

Mitrović, Marko Jumake, Todorović, Anastasija, Krstić, Nikola, Vrbanac, Zoran, Janevski, Aleksandar, Lazarević Macanović, Mirjana, "Radiološki pregled zuba  kunića – tehnike pregleda i  interpretacija snimki" in Veterinarska Stanica, 54, no. 5 (2023):581-589,
https://doi.org/https://doi.org/10.46419/vs.54.5.5 . .

TY  - JOUR
AU  - Vitorović, Duško
AU  - Božičković, Ivana
AU  - Lukić, Miloš
AU  - Relić, Renata
AU  - Škrbić, Zdenka
AU  - Petričević, Veselin
AU  - Lazarević Macanović, Mirjana
AU  - Krstić, Nikola
PY  - 2023
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/3001
AB  - The first few weeks after broilers hatch are the period of most intense bone growthand development, and the time when they are most susceptible to the in fluence ofvarious external and internal factors. Research in the recent decades has focused on theinvolvement of melatonin in bone development during early life in chickens. Melatoninrelease from the pineal gland has a circadian rhythm, with the highest levels circulatingduring the night and decreasing during the light phase of the day. Various types oflighting are used in intensive broiler production. In this study, the effects of melatoninon the tibial structure and growth of broilers were investigated. During the first twoweeks of life, two groups of chickens were kept under continuous light and fed thesame diet, with the experimental group receiving melatonin in the amount of 0.03 g/kg of feed. The results obtained showed that the addition of melatonin in the diet hadpositive effects on the development and growth of the tibia, which was expressed ina signi ficantly greater thickness of the diaphysis and cortical bone of the diaphysis,higher breaking force and higher values of alkaline phosphatase activity. The corticalbone mineral density of the tibia did not differ signi ficantly between the groups ofchicken.
PB  - University of Belgrade - Faculty of Veterinary Medicine
T2  - Acta Veterinaria
T1  - Tibia growth and development in broiler chicks reared under continuous light and melatonin dietary supplementation during the first two weeks of life
VL  - 73
IS  - 2
SP  - 262
EP  - 270
DO  - 10.2478/acve-2023-0020
ER  - 

@article{
author = "Vitorović, Duško and Božičković, Ivana and Lukić, Miloš and Relić, Renata and Škrbić, Zdenka and Petričević, Veselin and Lazarević Macanović, Mirjana and Krstić, Nikola",
year = "2023",
abstract = "The first few weeks after broilers hatch are the period of most intense bone growthand development, and the time when they are most susceptible to the in fluence ofvarious external and internal factors. Research in the recent decades has focused on theinvolvement of melatonin in bone development during early life in chickens. Melatoninrelease from the pineal gland has a circadian rhythm, with the highest levels circulatingduring the night and decreasing during the light phase of the day. Various types oflighting are used in intensive broiler production. In this study, the effects of melatoninon the tibial structure and growth of broilers were investigated. During the first twoweeks of life, two groups of chickens were kept under continuous light and fed thesame diet, with the experimental group receiving melatonin in the amount of 0.03 g/kg of feed. The results obtained showed that the addition of melatonin in the diet hadpositive effects on the development and growth of the tibia, which was expressed ina signi ficantly greater thickness of the diaphysis and cortical bone of the diaphysis,higher breaking force and higher values of alkaline phosphatase activity. The corticalbone mineral density of the tibia did not differ signi ficantly between the groups ofchicken.",
publisher = "University of Belgrade - Faculty of Veterinary Medicine",
journal = "Acta Veterinaria",
title = "Tibia growth and development in broiler chicks reared under continuous light and melatonin dietary supplementation during the first two weeks of life",
volume = "73",
number = "2",
pages = "262-270",
doi = "10.2478/acve-2023-0020"
}

Vitorović, D., Božičković, I., Lukić, M., Relić, R., Škrbić, Z., Petričević, V., Lazarević Macanović, M.,& Krstić, N.. (2023). Tibia growth and development in broiler chicks reared under continuous light and melatonin dietary supplementation during the first two weeks of life. in Acta Veterinaria
University of Belgrade - Faculty of Veterinary Medicine., 73(2), 262-270.
https://doi.org/10.2478/acve-2023-0020

Vitorović D, Božičković I, Lukić M, Relić R, Škrbić Z, Petričević V, Lazarević Macanović M, Krstić N. Tibia growth and development in broiler chicks reared under continuous light and melatonin dietary supplementation during the first two weeks of life. in Acta Veterinaria. 2023;73(2):262-270.
doi:10.2478/acve-2023-0020 .

Vitorović, Duško, Božičković, Ivana, Lukić, Miloš, Relić, Renata, Škrbić, Zdenka, Petričević, Veselin, Lazarević Macanović, Mirjana, Krstić, Nikola, "Tibia growth and development in broiler chicks reared under continuous light and melatonin dietary supplementation during the first two weeks of life" in Acta Veterinaria, 73, no. 2 (2023):262-270,
https://doi.org/10.2478/acve-2023-0020 . .

TY  - CONF
AU  - Mitrović, Marko Jumake
AU  - Todorović, Anastasija
AU  - Krstić, Nikola
AU  - Lazarević Macanović, Mirjana
PY  - 2023
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/3002
AB  - Cilj ove radionice je da se polaznici upoznaju sa tehnikama radiološkog pregleda abdominalnih organa kunića, pravilnom analizom
rendgenskih snimaka, kao i sa rendgenskom anatomijom organa gastrointestinalnog i urogenitalnog sistema ovih životinja. U drugom delu
radionice biće detaljno analizirana patološka stanja koja se najčešće
javljaju u svakodnevnoj kliničkoj praksi.
PB  - Beograd : Fakultet veterinarske medicine, Centar za izdavačku delatnost i promet učila
C3  - XLIV seminar za inovacije znanja veterinara, Beograd, 24. februar 2023
T1  - Rendgenska dijagnostika najčešćih patoloških stanja abdominalnih organa kod kunića
SP  - 129
EP  - 133
UR  - https://hdl.handle.net/21.15107/rcub_veterinar_3002
ER  - 

@conference{
author = "Mitrović, Marko Jumake and Todorović, Anastasija and Krstić, Nikola and Lazarević Macanović, Mirjana",
year = "2023",
abstract = "Cilj ove radionice je da se polaznici upoznaju sa tehnikama radiološkog pregleda abdominalnih organa kunića, pravilnom analizom
rendgenskih snimaka, kao i sa rendgenskom anatomijom organa gastrointestinalnog i urogenitalnog sistema ovih životinja. U drugom delu
radionice biće detaljno analizirana patološka stanja koja se najčešće
javljaju u svakodnevnoj kliničkoj praksi.",
publisher = "Beograd : Fakultet veterinarske medicine, Centar za izdavačku delatnost i promet učila",
journal = "XLIV seminar za inovacije znanja veterinara, Beograd, 24. februar 2023",
title = "Rendgenska dijagnostika najčešćih patoloških stanja abdominalnih organa kod kunića",
pages = "129-133",
url = "https://hdl.handle.net/21.15107/rcub_veterinar_3002"
}

Mitrović, M. J., Todorović, A., Krstić, N.,& Lazarević Macanović, M.. (2023). Rendgenska dijagnostika najčešćih patoloških stanja abdominalnih organa kod kunića. in XLIV seminar za inovacije znanja veterinara, Beograd, 24. februar 2023
Beograd : Fakultet veterinarske medicine, Centar za izdavačku delatnost i promet učila., 129-133.
https://hdl.handle.net/21.15107/rcub_veterinar_3002

Mitrović MJ, Todorović A, Krstić N, Lazarević Macanović M. Rendgenska dijagnostika najčešćih patoloških stanja abdominalnih organa kod kunića. in XLIV seminar za inovacije znanja veterinara, Beograd, 24. februar 2023. 2023;:129-133.
https://hdl.handle.net/21.15107/rcub_veterinar_3002 .

Mitrović, Marko Jumake, Todorović, Anastasija, Krstić, Nikola, Lazarević Macanović, Mirjana, "Rendgenska dijagnostika najčešćih patoloških stanja abdominalnih organa kod kunića" in XLIV seminar za inovacije znanja veterinara, Beograd, 24. februar 2023 (2023):129-133,
https://hdl.handle.net/21.15107/rcub_veterinar_3002 .

TY  - JOUR
AU  - Mitrović, Marko Jumake
AU  - Todorović, Anastasija
AU  - Tatalović, Nikola
AU  - Janevski, Aleksandar
AU  - Lazarević Macanović, Mirjana
PY  - 2023
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/2970
AB  - Dacryocystography is a specific method of radiological examination of the nasolacrimal apparatus based on the use of a positive contrast agent, which allows the assessment of its morphology and patency. Pathological conditions of the nasolacrimal apparatus in rabbits are very common in clinical practice, and the disturbance of its patency is usually a consequence of dental diseases or respiratory infections. The aim of this article is to present the most common pathological conditions that can affect the patency of the nasolacrimal apparatus in rabbits, a detailed anatomical description of the nasolacrimal apparatus in these animals, and the technique for performing dacriyocystography.
PB  - Beograd : Fakultet veterinarske medicine, Centar za izdavačku delatnost i promet učila
T2  - Veterinarski glasnik
T1  - Dacryocystography in rabbits
VL  - 77
IS  - 2
SP  - 87
EP  - 96
DO  - https://doi.org/10.2298/VETGL230115002M
ER  - 

@article{
author = "Mitrović, Marko Jumake and Todorović, Anastasija and Tatalović, Nikola and Janevski, Aleksandar and Lazarević Macanović, Mirjana",
year = "2023",
abstract = "Dacryocystography is a specific method of radiological examination of the nasolacrimal apparatus based on the use of a positive contrast agent, which allows the assessment of its morphology and patency. Pathological conditions of the nasolacrimal apparatus in rabbits are very common in clinical practice, and the disturbance of its patency is usually a consequence of dental diseases or respiratory infections. The aim of this article is to present the most common pathological conditions that can affect the patency of the nasolacrimal apparatus in rabbits, a detailed anatomical description of the nasolacrimal apparatus in these animals, and the technique for performing dacriyocystography.",
publisher = "Beograd : Fakultet veterinarske medicine, Centar za izdavačku delatnost i promet učila",
journal = "Veterinarski glasnik",
title = "Dacryocystography in rabbits",
volume = "77",
number = "2",
pages = "87-96",
doi = "https://doi.org/10.2298/VETGL230115002M"
}

Mitrović, M. J., Todorović, A., Tatalović, N., Janevski, A.,& Lazarević Macanović, M.. (2023). Dacryocystography in rabbits. in Veterinarski glasnik
Beograd : Fakultet veterinarske medicine, Centar za izdavačku delatnost i promet učila., 77(2), 87-96.
https://doi.org/https://doi.org/10.2298/VETGL230115002M

Mitrović MJ, Todorović A, Tatalović N, Janevski A, Lazarević Macanović M. Dacryocystography in rabbits. in Veterinarski glasnik. 2023;77(2):87-96.
doi:https://doi.org/10.2298/VETGL230115002M .

Mitrović, Marko Jumake, Todorović, Anastasija, Tatalović, Nikola, Janevski, Aleksandar, Lazarević Macanović, Mirjana, "Dacryocystography in rabbits" in Veterinarski glasnik, 77, no. 2 (2023):87-96,
https://doi.org/https://doi.org/10.2298/VETGL230115002M . .

TY  - JOUR
AU  - Mitrović, Marko Jumake
AU  - Kitanović, Sara
AU  - Tatalović, Nikola
AU  - Todorović, Anastasija
AU  - Lazarević Macanović, Mirjana
PY  - 2023
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/2730
AB  - Numerous studies are based on the use of animal models; however, in bipedal andtetrapedal organisms there are significant differences in the biomechanics of the spinalcolumn, which can significantly impair the quality and applicability of the resultsobtained. The aim of this study is to obtain basic data on the morphometric parametersof guinea pig lumbar vertebrae, the analysis of which will indicate the location of thebiggest mechanical load. The lumbar vertebra morphometry test was performed bymeans of X-ray imageing obtained from 12 guinea pigs, with equal numbers of malesand females. The results of investigations show that guinea pig lumbar vertebrae havean irregular trapezoid geometry and that the measured body lengths of L4 and L5 arethe largest. The height parameters determined in the medial level showed that L4 hadthe most concave body. Moreover, L4 had the greatest depth of the spinal canal at thesame measurement level. Consequently, in guinea pigs, the greatest load is in the L4region, unlike in humans, where, due to the axial load of the spinal column, the highestpressure is exerted on the last lumbar vertebrae.
PB  - Belgrade : Faculty of Veterinary Medicine
T2  - Acta Veterinaria
T1  - Radiological Investigation of Guinea Pig (Cavia porcellus) Lumbar Vertebral Morphology - A Biomechanical Aspect
VL  - 73
IS  - 1
SP  - 55
EP  - 70
DO  - 10.2478/acve-2023-0005
ER  - 

@article{
author = "Mitrović, Marko Jumake and Kitanović, Sara and Tatalović, Nikola and Todorović, Anastasija and Lazarević Macanović, Mirjana",
year = "2023",
abstract = "Numerous studies are based on the use of animal models; however, in bipedal andtetrapedal organisms there are significant differences in the biomechanics of the spinalcolumn, which can significantly impair the quality and applicability of the resultsobtained. The aim of this study is to obtain basic data on the morphometric parametersof guinea pig lumbar vertebrae, the analysis of which will indicate the location of thebiggest mechanical load. The lumbar vertebra morphometry test was performed bymeans of X-ray imageing obtained from 12 guinea pigs, with equal numbers of malesand females. The results of investigations show that guinea pig lumbar vertebrae havean irregular trapezoid geometry and that the measured body lengths of L4 and L5 arethe largest. The height parameters determined in the medial level showed that L4 hadthe most concave body. Moreover, L4 had the greatest depth of the spinal canal at thesame measurement level. Consequently, in guinea pigs, the greatest load is in the L4region, unlike in humans, where, due to the axial load of the spinal column, the highestpressure is exerted on the last lumbar vertebrae.",
publisher = "Belgrade : Faculty of Veterinary Medicine",
journal = "Acta Veterinaria",
title = "Radiological Investigation of Guinea Pig (Cavia porcellus) Lumbar Vertebral Morphology - A Biomechanical Aspect",
volume = "73",
number = "1",
pages = "55-70",
doi = "10.2478/acve-2023-0005"
}

Mitrović, M. J., Kitanović, S., Tatalović, N., Todorović, A.,& Lazarević Macanović, M.. (2023). Radiological Investigation of Guinea Pig (Cavia porcellus) Lumbar Vertebral Morphology - A Biomechanical Aspect. in Acta Veterinaria
Belgrade : Faculty of Veterinary Medicine., 73(1), 55-70.
https://doi.org/10.2478/acve-2023-0005

Mitrović MJ, Kitanović S, Tatalović N, Todorović A, Lazarević Macanović M. Radiological Investigation of Guinea Pig (Cavia porcellus) Lumbar Vertebral Morphology - A Biomechanical Aspect. in Acta Veterinaria. 2023;73(1):55-70.
doi:10.2478/acve-2023-0005 .

Mitrović, Marko Jumake, Kitanović, Sara, Tatalović, Nikola, Todorović, Anastasija, Lazarević Macanović, Mirjana, "Radiological Investigation of Guinea Pig (Cavia porcellus) Lumbar Vertebral Morphology - A Biomechanical Aspect" in Acta Veterinaria, 73, no. 1 (2023):55-70,
https://doi.org/10.2478/acve-2023-0005 . .

TY  - JOUR
AU  - Mitrović, Marko Jumake
AU  - Todorović, Anastasija
AU  - Lazarević Macanović, Mirjana
PY  - 2023
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/2874
AB  - Pathological conditions of rabbit teeth are very common in clinical practice and may also lead to deathdue to serious complications. Therefore, special attention should be paid to early diagnosis to allow timelytherapy. Radiographic diagnosis is a simple, quick and inevitable procedure to assess the condition of theteeth. Nevertheless, radiological examination of rabbit teeth has some peculiarities that are reflected inthe imaging procedures and interpretation of radiographs in comparison with other mammalian species.
PB  - Crimson Publishers
T2  - Clinical Research in Animal Science
T1  - Radiological Examination of Incisor Teeth in Rabbit (Oryctolagus Cuniculus)
VL  - 2
IS  - 5
SP  - 1
EP  - 4
DO  - 10.31031/CRAS.2023.02.000548
ER  - 

@article{
author = "Mitrović, Marko Jumake and Todorović, Anastasija and Lazarević Macanović, Mirjana",
year = "2023",
abstract = "Pathological conditions of rabbit teeth are very common in clinical practice and may also lead to deathdue to serious complications. Therefore, special attention should be paid to early diagnosis to allow timelytherapy. Radiographic diagnosis is a simple, quick and inevitable procedure to assess the condition of theteeth. Nevertheless, radiological examination of rabbit teeth has some peculiarities that are reflected inthe imaging procedures and interpretation of radiographs in comparison with other mammalian species.",
publisher = "Crimson Publishers",
journal = "Clinical Research in Animal Science",
title = "Radiological Examination of Incisor Teeth in Rabbit (Oryctolagus Cuniculus)",
volume = "2",
number = "5",
pages = "1-4",
doi = "10.31031/CRAS.2023.02.000548"
}

Mitrović, M. J., Todorović, A.,& Lazarević Macanović, M.. (2023). Radiological Examination of Incisor Teeth in Rabbit (Oryctolagus Cuniculus). in Clinical Research in Animal Science
Crimson Publishers., 2(5), 1-4.
https://doi.org/10.31031/CRAS.2023.02.000548

Mitrović MJ, Todorović A, Lazarević Macanović M. Radiological Examination of Incisor Teeth in Rabbit (Oryctolagus Cuniculus). in Clinical Research in Animal Science. 2023;2(5):1-4.
doi:10.31031/CRAS.2023.02.000548 .

Mitrović, Marko Jumake, Todorović, Anastasija, Lazarević Macanović, Mirjana, "Radiological Examination of Incisor Teeth in Rabbit (Oryctolagus Cuniculus)" in Clinical Research in Animal Science, 2, no. 5 (2023):1-4,
https://doi.org/10.31031/CRAS.2023.02.000548 . .

TY  - JOUR
AU  - Todorović, Anastasija
AU  - Lazarević Macanović, Mirjana
AU  - Mitrović, Marko Jumake
AU  - Krstić, Nikola
AU  - van Bree, Henri J. J.
AU  - Gielen, Ingrid M. L. V.
PY  - 2022
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/2500
AB  - Cranial cruciate ligament disease is a common pathological condition in dogs that is often presented in daily clinical practice. Different risk factors for the development of this condition include breed, sex, age, bodyweight and neuter status, as well as different biological and biomechanical mechanisms. In the literature, special attention has been paid to the role of the tibial plateau angle in damage to the cranial cruciate ligament. Although the disease was first described at the beginning of last century, and since then different surgical methods have been developed to treat it, its aetiology remains unclear. In this review, contemporary literature data related to the role of tibial plateau angle in canine cranial cruciate ligament rupture are presented.
PB  - Thieme Gruppe
T2  - Veterinary Comparative  Orthopaedics and Traumatology
T1  - The Role of Tibial Plateau Angle in Canine Cruciate Ligament Rupture—A Review of the Literature
VL  - 35
IS  - 6
SP  - 351
EP  - 361
DO  - 10.1055/s-0042-1750316
ER  - 

@article{
author = "Todorović, Anastasija and Lazarević Macanović, Mirjana and Mitrović, Marko Jumake and Krstić, Nikola and van Bree, Henri J. J. and Gielen, Ingrid M. L. V.",
year = "2022",
abstract = "Cranial cruciate ligament disease is a common pathological condition in dogs that is often presented in daily clinical practice. Different risk factors for the development of this condition include breed, sex, age, bodyweight and neuter status, as well as different biological and biomechanical mechanisms. In the literature, special attention has been paid to the role of the tibial plateau angle in damage to the cranial cruciate ligament. Although the disease was first described at the beginning of last century, and since then different surgical methods have been developed to treat it, its aetiology remains unclear. In this review, contemporary literature data related to the role of tibial plateau angle in canine cranial cruciate ligament rupture are presented.",
publisher = "Thieme Gruppe",
journal = "Veterinary Comparative  Orthopaedics and Traumatology",
title = "The Role of Tibial Plateau Angle in Canine Cruciate Ligament Rupture—A Review of the Literature",
volume = "35",
number = "6",
pages = "351-361",
doi = "10.1055/s-0042-1750316"
}

Todorović, A., Lazarević Macanović, M., Mitrović, M. J., Krstić, N., van Bree, H. J. J.,& Gielen, I. M. L. V.. (2022). The Role of Tibial Plateau Angle in Canine Cruciate Ligament Rupture—A Review of the Literature. in Veterinary Comparative  Orthopaedics and Traumatology
Thieme Gruppe., 35(6), 351-361.
https://doi.org/10.1055/s-0042-1750316

Todorović A, Lazarević Macanović M, Mitrović MJ, Krstić N, van Bree HJJ, Gielen IMLV. The Role of Tibial Plateau Angle in Canine Cruciate Ligament Rupture—A Review of the Literature. in Veterinary Comparative  Orthopaedics and Traumatology. 2022;35(6):351-361.
doi:10.1055/s-0042-1750316 .

Todorović, Anastasija, Lazarević Macanović, Mirjana, Mitrović, Marko Jumake, Krstić, Nikola, van Bree, Henri J. J., Gielen, Ingrid M. L. V., "The Role of Tibial Plateau Angle in Canine Cruciate Ligament Rupture—A Review of the Literature" in Veterinary Comparative  Orthopaedics and Traumatology, 35, no. 6 (2022):351-361,
https://doi.org/10.1055/s-0042-1750316 . .

TY  - CONF
AU  - Mitrović, Marko Jumake
AU  - Todorović, Anastasija
AU  - Krstić, Nikola
AU  - Lazarević Macanović, Mirjana
PY  - 2021
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/2001
AB  - Kunići i većina glodara imaju aradikularne hipsodontne zube koji se odlikuju stalnim rastom tokom čitavog života, zbog čega je neop- hodno da se oni neprekidno troše. Nedovoljno poznavanje osnovnih bioloških odlika ovih životinja i njihovih potreba u ishrani, često rezul- tira pojavom različitih patoloških promena na zubima od kojih su naj- zastupljenije malokluzija i apikalna elongacija korena zuba (rezervne krunice). Ukoliko se ove promene ne dijagnostikuju blagovremeno i ne preduzme odgovarajuća terapija, često dolazi do komplikacija u vidu pojave apscesa, opstrukcije nazolakrimalnog kanala sa posledičnim egzoftalmusom, kao i poremećaja funkcije organa respiratornog i/ili gastrointestinalnog sistema koji mogu imati letalan ishod. U svakod- nevnoj kliničkoj praksi, doktori veterinarske medicine se sve češće su- sreću sa ovom problematikom, a za postavljanje tačne dijagnoze kao i praćenje efekata terapije, neophodno je primeniti radiološke metode pregleda. Samim tim, osnovni cilj ove radionice je da se polaznici upo- znaju sa osobenostima zuba kunića i različitih vrsta glodara, kao i da savladaju tehnike radiološkog pregleda zuba i pregleda nazolakrimal- nog kanala uz primenu pozitivnog kontrastnog sredstva (dakriocisto- grafija) i da savladaju veštinu tumačenja dobijenih rendgenskih sni- maka. Tokom ove radionice, biće prikazana najčešća patološka stanja zuba kunića i glodara koja će biti detaljno diskutovana.
PB  - Fakultet veterinarske medicine, Centar za izdavačku delatnost i promet učila
C3  - Zbornik radova - XLII seminar inovacija znanja veterinara
T1  - Radiološke tehnike pregleda, interpretacija snimaka i dijagnostika najčešćih patoloških stanja zuba kunića i glodara
SP  - 179
EP  - 192
UR  - https://hdl.handle.net/21.15107/rcub_veterinar_2001
ER  - 

@conference{
author = "Mitrović, Marko Jumake and Todorović, Anastasija and Krstić, Nikola and Lazarević Macanović, Mirjana",
year = "2021",
abstract = "Kunići i većina glodara imaju aradikularne hipsodontne zube koji se odlikuju stalnim rastom tokom čitavog života, zbog čega je neop- hodno da se oni neprekidno troše. Nedovoljno poznavanje osnovnih bioloških odlika ovih životinja i njihovih potreba u ishrani, često rezul- tira pojavom različitih patoloških promena na zubima od kojih su naj- zastupljenije malokluzija i apikalna elongacija korena zuba (rezervne krunice). Ukoliko se ove promene ne dijagnostikuju blagovremeno i ne preduzme odgovarajuća terapija, često dolazi do komplikacija u vidu pojave apscesa, opstrukcije nazolakrimalnog kanala sa posledičnim egzoftalmusom, kao i poremećaja funkcije organa respiratornog i/ili gastrointestinalnog sistema koji mogu imati letalan ishod. U svakod- nevnoj kliničkoj praksi, doktori veterinarske medicine se sve češće su- sreću sa ovom problematikom, a za postavljanje tačne dijagnoze kao i praćenje efekata terapije, neophodno je primeniti radiološke metode pregleda. Samim tim, osnovni cilj ove radionice je da se polaznici upo- znaju sa osobenostima zuba kunića i različitih vrsta glodara, kao i da savladaju tehnike radiološkog pregleda zuba i pregleda nazolakrimal- nog kanala uz primenu pozitivnog kontrastnog sredstva (dakriocisto- grafija) i da savladaju veštinu tumačenja dobijenih rendgenskih sni- maka. Tokom ove radionice, biće prikazana najčešća patološka stanja zuba kunića i glodara koja će biti detaljno diskutovana.",
publisher = "Fakultet veterinarske medicine, Centar za izdavačku delatnost i promet učila",
journal = "Zbornik radova - XLII seminar inovacija znanja veterinara",
title = "Radiološke tehnike pregleda, interpretacija snimaka i dijagnostika najčešćih patoloških stanja zuba kunića i glodara",
pages = "179-192",
url = "https://hdl.handle.net/21.15107/rcub_veterinar_2001"
}

Mitrović, M. J., Todorović, A., Krstić, N.,& Lazarević Macanović, M.. (2021). Radiološke tehnike pregleda, interpretacija snimaka i dijagnostika najčešćih patoloških stanja zuba kunića i glodara. in Zbornik radova - XLII seminar inovacija znanja veterinara
Fakultet veterinarske medicine, Centar za izdavačku delatnost i promet učila., 179-192.
https://hdl.handle.net/21.15107/rcub_veterinar_2001

Mitrović MJ, Todorović A, Krstić N, Lazarević Macanović M. Radiološke tehnike pregleda, interpretacija snimaka i dijagnostika najčešćih patoloških stanja zuba kunića i glodara. in Zbornik radova - XLII seminar inovacija znanja veterinara. 2021;:179-192.
https://hdl.handle.net/21.15107/rcub_veterinar_2001 .

Mitrović, Marko Jumake, Todorović, Anastasija, Krstić, Nikola, Lazarević Macanović, Mirjana, "Radiološke tehnike pregleda, interpretacija snimaka i dijagnostika najčešćih patoloških stanja zuba kunića i glodara" in Zbornik radova - XLII seminar inovacija znanja veterinara (2021):179-192,
https://hdl.handle.net/21.15107/rcub_veterinar_2001 .

TY  - JOUR
AU  - Mitrović, Marko Jumake
AU  - Ciraj-Bjelac, O.
AU  - Jovanović, Z.
AU  - Krstić, Nikola
AU  - Nikezic, D.
AU  - Krstić, D.
AU  - Živković, M.
AU  - Lazarević Macanović, Mirjana
PY  - 2021
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/2218
AB  - The objective of this work was to assess absorbed doses in organs and tissues of a rabbit, following computed tomography (CT) examinations, using a dedicated 3D voxel model. Absorbed doses in relevant organs were calculated using the MCNP5 Monte Carlo software. Calculations were perfomed for two standard CT protocols, using tube voltages of 110 kVp and 130 kVp. Absorbed doses were calculated in 11 organs and tissues, i.e., skin, bones, brain, muscles, heart, lungs, liver, spleen, kidney, testicles, and fat tissue. The doses ranged from 15.3 to 28.3 mGy, and from 40.2 to 74.3 mGy, in the two investigated protocols. The organs that received the highest dose were bones and kidneys. In contrast, brain and spleen were organs that received the smallest doses. Doses in organs which are stretched along the body did not change significantly with distance. On the other hand, doses in organs which are localized in the body showed maximums and minimums. Using the voxel model, it is possible to calculate the dose distribution in the rabbit’s body after CT scans, and study the potential biological effects of CT doses in certain organs. The voxel model presented in this work can be used to calculated doses in all radiation experiments in which rabbits are used as experimental animals.
PB  - Springer
T2  - Radiation and Environmental Biophysics
T1  - Voxel model of a rabbit: assessment of absorbed doses in organs after CT examination performed by two different protocols
DO  - 10.1007/s00411-021-00941-7
ER  - 

@article{
author = "Mitrović, Marko Jumake and Ciraj-Bjelac, O. and Jovanović, Z. and Krstić, Nikola and Nikezic, D. and Krstić, D. and Živković, M. and Lazarević Macanović, Mirjana",
year = "2021",
abstract = "The objective of this work was to assess absorbed doses in organs and tissues of a rabbit, following computed tomography (CT) examinations, using a dedicated 3D voxel model. Absorbed doses in relevant organs were calculated using the MCNP5 Monte Carlo software. Calculations were perfomed for two standard CT protocols, using tube voltages of 110 kVp and 130 kVp. Absorbed doses were calculated in 11 organs and tissues, i.e., skin, bones, brain, muscles, heart, lungs, liver, spleen, kidney, testicles, and fat tissue. The doses ranged from 15.3 to 28.3 mGy, and from 40.2 to 74.3 mGy, in the two investigated protocols. The organs that received the highest dose were bones and kidneys. In contrast, brain and spleen were organs that received the smallest doses. Doses in organs which are stretched along the body did not change significantly with distance. On the other hand, doses in organs which are localized in the body showed maximums and minimums. Using the voxel model, it is possible to calculate the dose distribution in the rabbit’s body after CT scans, and study the potential biological effects of CT doses in certain organs. The voxel model presented in this work can be used to calculated doses in all radiation experiments in which rabbits are used as experimental animals.",
publisher = "Springer",
journal = "Radiation and Environmental Biophysics",
title = "Voxel model of a rabbit: assessment of absorbed doses in organs after CT examination performed by two different protocols",
doi = "10.1007/s00411-021-00941-7"
}

Mitrović, M. J., Ciraj-Bjelac, O., Jovanović, Z., Krstić, N., Nikezic, D., Krstić, D., Živković, M.,& Lazarević Macanović, M.. (2021). Voxel model of a rabbit: assessment of absorbed doses in organs after CT examination performed by two different protocols. in Radiation and Environmental Biophysics
Springer..
https://doi.org/10.1007/s00411-021-00941-7

Mitrović MJ, Ciraj-Bjelac O, Jovanović Z, Krstić N, Nikezic D, Krstić D, Živković M, Lazarević Macanović M. Voxel model of a rabbit: assessment of absorbed doses in organs after CT examination performed by two different protocols. in Radiation and Environmental Biophysics. 2021;.
doi:10.1007/s00411-021-00941-7 .

Mitrović, Marko Jumake, Ciraj-Bjelac, O., Jovanović, Z., Krstić, Nikola, Nikezic, D., Krstić, D., Živković, M., Lazarević Macanović, Mirjana, "Voxel model of a rabbit: assessment of absorbed doses in organs after CT examination performed by two different protocols" in Radiation and Environmental Biophysics (2021),
https://doi.org/10.1007/s00411-021-00941-7 . .

TY  - CONF
AU  - Todorović, Anastasija
AU  - Dingemanse, Walter
AU  - Lazarević Macanović, Mirjana
AU  - Müller-Gerbl, Magdalena
AU  - Mitrović, Marko Jumake
AU  - Jonkers, Ilse
AU  - Vander Sloten, Jos
AU  - van, Bree Henri
AU  - Gielen, Ingrid
PY  - 2021
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/2266
AB  - Introduction / Purpose:
The subchondral bone plate plays an important role in the load transfer across joints. The
subchondral bone density distribution is a reflection of the loading history of the joint,
and the heterogeneous density distribution expected to be reflected in the subchondral
bone material properties. The goal of this study was to evaluate the strength of the
subchondral bone plate of the canine talus and to correlate it to the subchondral bone
density.
Methods:
On twenty, paired, cadaver tali of different large breed dogs, test points were defined on
the subchondral bone plate. At these points the mechanical strength was determined by
indentation testing, registering the maximum penetration force, and the density was
measured by means of computer tomographic osteoabsorptiometry (CTOAM).
Results:
Neither the density nor the strength were distributed homogeneously over the surface of
the subchondral bone plate. In all specimens, a high correlation was found between the
subchondral bone density and the mechanical strength. The coefficient of determination
(r
2
) ranged from 0.78 to 0.96 with a mean of 0.89 and was statistically significant (p <
0.01). The location of the density maxima matched the location of maximal mechanical
strength. There was no significant difference in the location of the density maxima and
the strength maxima (p-value = 0.512).
Discussion / Conclusion:
CTOAM provides a non-invasive opportunity to not only assess and visualize the density
of the subchondral bone plate on densitograms but also the mechanical strength, and to
perform longitudinal studies on subchondral bone density and strength in dogs.
C3  - EVDI Online Congress
T1  - Density and strength distribution of the subchondral bone plate of the canine talus
SP  - 70
EP  - 70
UR  - https://hdl.handle.net/21.15107/rcub_veterinar_2266
ER  - 

@conference{
author = "Todorović, Anastasija and Dingemanse, Walter and Lazarević Macanović, Mirjana and Müller-Gerbl, Magdalena and Mitrović, Marko Jumake and Jonkers, Ilse and Vander Sloten, Jos and van, Bree Henri and Gielen, Ingrid",
year = "2021",
abstract = "Introduction / Purpose:
The subchondral bone plate plays an important role in the load transfer across joints. The
subchondral bone density distribution is a reflection of the loading history of the joint,
and the heterogeneous density distribution expected to be reflected in the subchondral
bone material properties. The goal of this study was to evaluate the strength of the
subchondral bone plate of the canine talus and to correlate it to the subchondral bone
density.
Methods:
On twenty, paired, cadaver tali of different large breed dogs, test points were defined on
the subchondral bone plate. At these points the mechanical strength was determined by
indentation testing, registering the maximum penetration force, and the density was
measured by means of computer tomographic osteoabsorptiometry (CTOAM).
Results:
Neither the density nor the strength were distributed homogeneously over the surface of
the subchondral bone plate. In all specimens, a high correlation was found between the
subchondral bone density and the mechanical strength. The coefficient of determination
(r
2
) ranged from 0.78 to 0.96 with a mean of 0.89 and was statistically significant (p <
0.01). The location of the density maxima matched the location of maximal mechanical
strength. There was no significant difference in the location of the density maxima and
the strength maxima (p-value = 0.512).
Discussion / Conclusion:
CTOAM provides a non-invasive opportunity to not only assess and visualize the density
of the subchondral bone plate on densitograms but also the mechanical strength, and to
perform longitudinal studies on subchondral bone density and strength in dogs.",
journal = "EVDI Online Congress",
title = "Density and strength distribution of the subchondral bone plate of the canine talus",
pages = "70-70",
url = "https://hdl.handle.net/21.15107/rcub_veterinar_2266"
}

Todorović, A., Dingemanse, W., Lazarević Macanović, M., Müller-Gerbl, M., Mitrović, M. J., Jonkers, I., Vander Sloten, J., van, B. H.,& Gielen, I.. (2021). Density and strength distribution of the subchondral bone plate of the canine talus. in EVDI Online Congress, 70-70.
https://hdl.handle.net/21.15107/rcub_veterinar_2266

Todorović A, Dingemanse W, Lazarević Macanović M, Müller-Gerbl M, Mitrović MJ, Jonkers I, Vander Sloten J, van BH, Gielen I. Density and strength distribution of the subchondral bone plate of the canine talus. in EVDI Online Congress. 2021;:70-70.
https://hdl.handle.net/21.15107/rcub_veterinar_2266 .

Todorović, Anastasija, Dingemanse, Walter, Lazarević Macanović, Mirjana, Müller-Gerbl, Magdalena, Mitrović, Marko Jumake, Jonkers, Ilse, Vander Sloten, Jos, van, Bree Henri, Gielen, Ingrid, "Density and strength distribution of the subchondral bone plate of the canine talus" in EVDI Online Congress (2021):70-70,
https://hdl.handle.net/21.15107/rcub_veterinar_2266 .

TY  - CONF
AU  - Marković, Lazar
AU  - Lazarević Macanović, Mirjana
AU  - Lužajić Božinovski, Tijana
AU  - Milovanović, Petar
AU  - Mitrović, Marko Jumake
AU  - Gajdov, Vladimir
AU  - Radovanović, Anita
AU  - Kovačević Filipović, Milica
AU  - Milošević, Ivan
PY  - 2020
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/2606
AB  - Radni konji se u Srbiji koriste kao tovarne životinje koje nose/vuku tovar, često teži od njihove telesne mase. Postavili smo hipotezu da opterećenje koje trpe utiče na pojavu lezija na koštano-zglobnom sistemu. Cilj ovog rada je bio da se uporedno prikaže prisustvo i stepen oštećenja zglobne hrskavice (ZH) i subhondralne kosti (SHK), distalnih kondilusa treće metatarzalne kosti kod starijeg radnog konja pomoću makroskopskog pregleda hrskavice, radioloških i histoloških metoda. Na lokalnoj klanici uzorkovani su kičični zglobovi ekstremiteta radnog pastuva, starog 10 godina. Uz pomoć kompjuterizovane tomografije (CT) utvrđene su promene samo na zglobu prednje leve noge. Nakon disekcije označenog zgloba, izvršena je biopsija ZH i SHK metakarpalne kosti u predelu oštećenja, a bioptati su snimljeni mikro CT-om nakon čega su deklacifikovani i ukalupljeni u parafin, i analizirani su preseci. Makroskopski je bilo vidljivo da je lokalizacija oštećenja ZH bila simetrična na medijalnim i lateralnim epikondilusima matakarpalnih i metatarzalnih kostiju svih ekstremiteta. Linije habanja i palmarne artroze bile su slabo do umereno izražene. Na nativnim rendgenogramima zglobova nisu uočene patološke promene. Analizom snimaka načinjenih CT-om uočena je promena u subhondralnoj zoni distalne epifize treće metakarpalne kosti u vidu pukotine, a oko nje je primetna zona skleroze SHK. Na mikro CT snimku uzorka koštanog tkiva uzetog u predelu lateralnog epikondilusa metakarpane kosti, takođe je uočljiva zona subhondralne skleroze. Najmarkatnije histološke promene na ZH su bile: na površini ZH undulacije i fisure, koje se pružaju i do duboke zone, mnogobrojne izogene grupe sa većim brojem hondrocita u lakuni, fokalni gubitak ćelija i mestimičnio prisustvo hipertrofičnih hondrocita. U SHK su primećene: neznatne lezije koštanog matriksa u vidu svetlijeg prebojavanja, blago remodeliranje kosti koje se karakteriše njenim napredovanjem ka kalcifikovanoj hrskavici. Dugotrajno opterećenje utiče na pojavu oštećenja SHK koje se može uočiti uz pomoć CT-a i histološkom analizom, dok se stepen oštećenja ZH može evaluirati makroskopski i histološki.
C3  - 25. godišnje savjetovanje doktora veterinarske medicine Republike Srpske (Bosna i Hercegovina), Teslić
T1  - Analiza promena na hrskavici i subhondralnoj kosti kiĉiĉnog zgloba radnog konja - radiološki i histološki pristup
SP  - 138
EP  - 141
UR  - https://hdl.handle.net/21.15107/rcub_veterinar_2606
ER  - 

@conference{
author = "Marković, Lazar and Lazarević Macanović, Mirjana and Lužajić Božinovski, Tijana and Milovanović, Petar and Mitrović, Marko Jumake and Gajdov, Vladimir and Radovanović, Anita and Kovačević Filipović, Milica and Milošević, Ivan",
year = "2020",
abstract = "Radni konji se u Srbiji koriste kao tovarne životinje koje nose/vuku tovar, često teži od njihove telesne mase. Postavili smo hipotezu da opterećenje koje trpe utiče na pojavu lezija na koštano-zglobnom sistemu. Cilj ovog rada je bio da se uporedno prikaže prisustvo i stepen oštećenja zglobne hrskavice (ZH) i subhondralne kosti (SHK), distalnih kondilusa treće metatarzalne kosti kod starijeg radnog konja pomoću makroskopskog pregleda hrskavice, radioloških i histoloških metoda. Na lokalnoj klanici uzorkovani su kičični zglobovi ekstremiteta radnog pastuva, starog 10 godina. Uz pomoć kompjuterizovane tomografije (CT) utvrđene su promene samo na zglobu prednje leve noge. Nakon disekcije označenog zgloba, izvršena je biopsija ZH i SHK metakarpalne kosti u predelu oštećenja, a bioptati su snimljeni mikro CT-om nakon čega su deklacifikovani i ukalupljeni u parafin, i analizirani su preseci. Makroskopski je bilo vidljivo da je lokalizacija oštećenja ZH bila simetrična na medijalnim i lateralnim epikondilusima matakarpalnih i metatarzalnih kostiju svih ekstremiteta. Linije habanja i palmarne artroze bile su slabo do umereno izražene. Na nativnim rendgenogramima zglobova nisu uočene patološke promene. Analizom snimaka načinjenih CT-om uočena je promena u subhondralnoj zoni distalne epifize treće metakarpalne kosti u vidu pukotine, a oko nje je primetna zona skleroze SHK. Na mikro CT snimku uzorka koštanog tkiva uzetog u predelu lateralnog epikondilusa metakarpane kosti, takođe je uočljiva zona subhondralne skleroze. Najmarkatnije histološke promene na ZH su bile: na površini ZH undulacije i fisure, koje se pružaju i do duboke zone, mnogobrojne izogene grupe sa većim brojem hondrocita u lakuni, fokalni gubitak ćelija i mestimičnio prisustvo hipertrofičnih hondrocita. U SHK su primećene: neznatne lezije koštanog matriksa u vidu svetlijeg prebojavanja, blago remodeliranje kosti koje se karakteriše njenim napredovanjem ka kalcifikovanoj hrskavici. Dugotrajno opterećenje utiče na pojavu oštećenja SHK koje se može uočiti uz pomoć CT-a i histološkom analizom, dok se stepen oštećenja ZH može evaluirati makroskopski i histološki.",
journal = "25. godišnje savjetovanje doktora veterinarske medicine Republike Srpske (Bosna i Hercegovina), Teslić",
title = "Analiza promena na hrskavici i subhondralnoj kosti kiĉiĉnog zgloba radnog konja - radiološki i histološki pristup",
pages = "138-141",
url = "https://hdl.handle.net/21.15107/rcub_veterinar_2606"
}

Marković, L., Lazarević Macanović, M., Lužajić Božinovski, T., Milovanović, P., Mitrović, M. J., Gajdov, V., Radovanović, A., Kovačević Filipović, M.,& Milošević, I.. (2020). Analiza promena na hrskavici i subhondralnoj kosti kiĉiĉnog zgloba radnog konja - radiološki i histološki pristup. in 25. godišnje savjetovanje doktora veterinarske medicine Republike Srpske (Bosna i Hercegovina), Teslić, 138-141.
https://hdl.handle.net/21.15107/rcub_veterinar_2606

Marković L, Lazarević Macanović M, Lužajić Božinovski T, Milovanović P, Mitrović MJ, Gajdov V, Radovanović A, Kovačević Filipović M, Milošević I. Analiza promena na hrskavici i subhondralnoj kosti kiĉiĉnog zgloba radnog konja - radiološki i histološki pristup. in 25. godišnje savjetovanje doktora veterinarske medicine Republike Srpske (Bosna i Hercegovina), Teslić. 2020;:138-141.
https://hdl.handle.net/21.15107/rcub_veterinar_2606 .

Marković, Lazar, Lazarević Macanović, Mirjana, Lužajić Božinovski, Tijana, Milovanović, Petar, Mitrović, Marko Jumake, Gajdov, Vladimir, Radovanović, Anita, Kovačević Filipović, Milica, Milošević, Ivan, "Analiza promena na hrskavici i subhondralnoj kosti kiĉiĉnog zgloba radnog konja - radiološki i histološki pristup" in 25. godišnje savjetovanje doktora veterinarske medicine Republike Srpske (Bosna i Hercegovina), Teslić (2020):138-141,
https://hdl.handle.net/21.15107/rcub_veterinar_2606 .

TY  - JOUR
AU  - Marinković, Darko
AU  - Lazarević Macanović, Mirjana
AU  - Krstić, Nikola
AU  - Ćirović, D.
AU  - Gielen, I.
PY  - 2019
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/1719
AB  - Craniomandibular osteopathy is a rare disorder in dogs, characterised by subperiosteal and extraperiosteal new bone proliferations on the skull, on the mandibles in particular and occasionally on long bones. Data about craniomandibular osteopathy in the golden jackal (Canis aureus) are lacking. This paper describes craniomandibular osteopathy in a seven-month-old animal. The mandibular region and the distal section of the hindlimb were examined radiologically and by CT. Both imaging modalities showed ossifying periosteal deposits localised on the left side of the mandible and irregular periosteal ossifying deposits covering the surface of the crural bones. Histopathology revealed new bone formation in the endosteum, periosteum and trabecular bone of the mandible and in the distal section of the hindlimb, but no inflammatory cells were found. Craniomandibular osteopathy in free-living canids has not yet been reported. However, the macroscopic imaging and histopathological features in this pup were consistent with the disease.
PB  - BMJ Publishing Group, London
T2  - Veterinary Record Case Reports
T1  - Craniomandibular osteopathy in a golden jackal (C anis aureus)
VL  - 7
IS  - 2
SP  - e000728
DO  - 10.1136/vetreccr-2018-000728
ER  - 

@article{
author = "Marinković, Darko and Lazarević Macanović, Mirjana and Krstić, Nikola and Ćirović, D. and Gielen, I.",
year = "2019",
abstract = "Craniomandibular osteopathy is a rare disorder in dogs, characterised by subperiosteal and extraperiosteal new bone proliferations on the skull, on the mandibles in particular and occasionally on long bones. Data about craniomandibular osteopathy in the golden jackal (Canis aureus) are lacking. This paper describes craniomandibular osteopathy in a seven-month-old animal. The mandibular region and the distal section of the hindlimb were examined radiologically and by CT. Both imaging modalities showed ossifying periosteal deposits localised on the left side of the mandible and irregular periosteal ossifying deposits covering the surface of the crural bones. Histopathology revealed new bone formation in the endosteum, periosteum and trabecular bone of the mandible and in the distal section of the hindlimb, but no inflammatory cells were found. Craniomandibular osteopathy in free-living canids has not yet been reported. However, the macroscopic imaging and histopathological features in this pup were consistent with the disease.",
publisher = "BMJ Publishing Group, London",
journal = "Veterinary Record Case Reports",
title = "Craniomandibular osteopathy in a golden jackal (C anis aureus)",
volume = "7",
number = "2",
pages = "e000728",
doi = "10.1136/vetreccr-2018-000728"
}

Marinković, D., Lazarević Macanović, M., Krstić, N., Ćirović, D.,& Gielen, I.. (2019). Craniomandibular osteopathy in a golden jackal (C anis aureus). in Veterinary Record Case Reports
BMJ Publishing Group, London., 7(2), e000728.
https://doi.org/10.1136/vetreccr-2018-000728

Marinković D, Lazarević Macanović M, Krstić N, Ćirović D, Gielen I. Craniomandibular osteopathy in a golden jackal (C anis aureus). in Veterinary Record Case Reports. 2019;7(2):e000728.
doi:10.1136/vetreccr-2018-000728 .

Marinković, Darko, Lazarević Macanović, Mirjana, Krstić, Nikola, Ćirović, D., Gielen, I., "Craniomandibular osteopathy in a golden jackal (C anis aureus)" in Veterinary Record Case Reports, 7, no. 2 (2019):e000728,
https://doi.org/10.1136/vetreccr-2018-000728 . .

TY  - JOUR
AU  - Dingemanse, Walter B.
AU  - Gielen, Ingrid
AU  - van Bree, Henri J. J.
AU  - Mueller-Gerbl, Magdalena
AU  - Krstić, Nikola
AU  - Mitrović, Marko Jumake
AU  - Ćirović, Duško
AU  - Lazarević Macanović, Mirjana
PY  - 2019
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/1744
AB  - Objective Subchondral bone density distribution can be used to study joint biomechanics non-invasively. Differences in joint loading between related species can aid in the understanding of joint loading and the development of certain types of orthopaedic pathology. This study was conducted to evaluate density distribution in the subchondral bone of the talus of different Canidae species, as a parameter reflecting the long-term joint loading in the tarsocrural joint. Materials and Methods The tarsal joints of cadaveric dogs of different breeds were included, that is, German Shepherd (n = 5), Bouvier des Flandres (n = 3) and Labrador Retriever (n = 6). Additionally, golden jackals (n = 5) (Canis aureus) and wolves (n = 5) (Canis lupus) were included. Consecutive computed tomography slices were made and the subchondral bone density distribution was evaluated using computer tomographic osteoabsorptiometry. Different breeds and species were visually compared. Results Differences were found in the subchondral bone density distribution of the talus between breeds and between species (Canis familiaris, Canis lupus and Canis aureus). Discussion and Conclusion Based on the density distribution, there are differences in loading conditions of the tarsocrural joint in different species of Canidae. The joint loading distribution is very similar between dogs of the same breed and within the same species. Although between-breed differences can be explained by conformational differences, the between-species differences remain subject to further research.
PB  - Georg Thieme Verlag Kg, Stuttgart
T2  - Veterinary and Comparative Orthopaedics and Traumatology
T1  - Spatial Subchondral Bone Density Reflecting Joint Loading of the Talus in Different Canidae
VL  - 32
IS  - 3
SP  - 207
EP  - 214
DO  - 10.1055/s-0039-1685511
ER  - 

@article{
author = "Dingemanse, Walter B. and Gielen, Ingrid and van Bree, Henri J. J. and Mueller-Gerbl, Magdalena and Krstić, Nikola and Mitrović, Marko Jumake and Ćirović, Duško and Lazarević Macanović, Mirjana",
year = "2019",
abstract = "Objective Subchondral bone density distribution can be used to study joint biomechanics non-invasively. Differences in joint loading between related species can aid in the understanding of joint loading and the development of certain types of orthopaedic pathology. This study was conducted to evaluate density distribution in the subchondral bone of the talus of different Canidae species, as a parameter reflecting the long-term joint loading in the tarsocrural joint. Materials and Methods The tarsal joints of cadaveric dogs of different breeds were included, that is, German Shepherd (n = 5), Bouvier des Flandres (n = 3) and Labrador Retriever (n = 6). Additionally, golden jackals (n = 5) (Canis aureus) and wolves (n = 5) (Canis lupus) were included. Consecutive computed tomography slices were made and the subchondral bone density distribution was evaluated using computer tomographic osteoabsorptiometry. Different breeds and species were visually compared. Results Differences were found in the subchondral bone density distribution of the talus between breeds and between species (Canis familiaris, Canis lupus and Canis aureus). Discussion and Conclusion Based on the density distribution, there are differences in loading conditions of the tarsocrural joint in different species of Canidae. The joint loading distribution is very similar between dogs of the same breed and within the same species. Although between-breed differences can be explained by conformational differences, the between-species differences remain subject to further research.",
publisher = "Georg Thieme Verlag Kg, Stuttgart",
journal = "Veterinary and Comparative Orthopaedics and Traumatology",
title = "Spatial Subchondral Bone Density Reflecting Joint Loading of the Talus in Different Canidae",
volume = "32",
number = "3",
pages = "207-214",
doi = "10.1055/s-0039-1685511"
}

Dingemanse, W. B., Gielen, I., van Bree, H. J. J., Mueller-Gerbl, M., Krstić, N., Mitrović, M. J., Ćirović, D.,& Lazarević Macanović, M.. (2019). Spatial Subchondral Bone Density Reflecting Joint Loading of the Talus in Different Canidae. in Veterinary and Comparative Orthopaedics and Traumatology
Georg Thieme Verlag Kg, Stuttgart., 32(3), 207-214.
https://doi.org/10.1055/s-0039-1685511

Dingemanse WB, Gielen I, van Bree HJJ, Mueller-Gerbl M, Krstić N, Mitrović MJ, Ćirović D, Lazarević Macanović M. Spatial Subchondral Bone Density Reflecting Joint Loading of the Talus in Different Canidae. in Veterinary and Comparative Orthopaedics and Traumatology. 2019;32(3):207-214.
doi:10.1055/s-0039-1685511 .

Dingemanse, Walter B., Gielen, Ingrid, van Bree, Henri J. J., Mueller-Gerbl, Magdalena, Krstić, Nikola, Mitrović, Marko Jumake, Ćirović, Duško, Lazarević Macanović, Mirjana, "Spatial Subchondral Bone Density Reflecting Joint Loading of the Talus in Different Canidae" in Veterinary and Comparative Orthopaedics and Traumatology, 32, no. 3 (2019):207-214,
https://doi.org/10.1055/s-0039-1685511 . .

TY  - JOUR
AU  - Mitrović, Marko Jumake
AU  - Tatalović, Nikola R.
AU  - Nikolic-Kokić, Aleksandra L.
AU  - Ciraj-Bjelac, Olivera F.
AU  - Krstić, Nikola
AU  - Orescanin-Dusić, Zorana S.
AU  - Krstić, Dragana Z.
AU  - Jovanović, Zoran M.
AU  - Blagojević, Duško P.
AU  - Lazarević Macanović, Mirjana
PY  - 2018
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/1574
AB  - In recent years, computed tomography (CT) has become very common in veterinary medicine. It is well known that testicles are organs with high radiosensitivity and their function can be impaired even after exposure to low radiation doses. In this work, we calculated the absorbed radiation doses after CT was performed with different voltage/current levels and correlated it with the activity of antioxidant enzymes in rabbit testicles. Two hours after CT, the activities of catalase (CAT) and glutathione peroxidase (GSH-Px) were increased in the testicles of animals that received an absorbed dose of 29.2 mGy. The same changes, along with elevated glutathione reductase (GR) activity, were observed after 7 days in animals that received the highest absorbed dose (46.3 mGy). It would appear that absorbed doses above 27.8 mGy provoked the antioxidant reaction but the time scale of the reaction was dose-dependent. Examination of the obtained results revealed that the main denominator of CT influence was a higher current. Our results suggest that CT influences the antioxidant status in rabbit testicles. The changes in antioxidant enzyme activities were dose- and time-dependent and influenced by the applied current.
PB  - Srpsko biološko društvo, Beograd
T2  - Archives of Biological Sciences
T1  - Influence of absorbed radiation dose following computed tomography on the antioxidative status in rabbit testicles
VL  - 70
IS  - 4
SP  - 675
EP  - 680
DO  - 10.2298/ABS180413029M
ER  - 

@article{
author = "Mitrović, Marko Jumake and Tatalović, Nikola R. and Nikolic-Kokić, Aleksandra L. and Ciraj-Bjelac, Olivera F. and Krstić, Nikola and Orescanin-Dusić, Zorana S. and Krstić, Dragana Z. and Jovanović, Zoran M. and Blagojević, Duško P. and Lazarević Macanović, Mirjana",
year = "2018",
abstract = "In recent years, computed tomography (CT) has become very common in veterinary medicine. It is well known that testicles are organs with high radiosensitivity and their function can be impaired even after exposure to low radiation doses. In this work, we calculated the absorbed radiation doses after CT was performed with different voltage/current levels and correlated it with the activity of antioxidant enzymes in rabbit testicles. Two hours after CT, the activities of catalase (CAT) and glutathione peroxidase (GSH-Px) were increased in the testicles of animals that received an absorbed dose of 29.2 mGy. The same changes, along with elevated glutathione reductase (GR) activity, were observed after 7 days in animals that received the highest absorbed dose (46.3 mGy). It would appear that absorbed doses above 27.8 mGy provoked the antioxidant reaction but the time scale of the reaction was dose-dependent. Examination of the obtained results revealed that the main denominator of CT influence was a higher current. Our results suggest that CT influences the antioxidant status in rabbit testicles. The changes in antioxidant enzyme activities were dose- and time-dependent and influenced by the applied current.",
publisher = "Srpsko biološko društvo, Beograd",
journal = "Archives of Biological Sciences",
title = "Influence of absorbed radiation dose following computed tomography on the antioxidative status in rabbit testicles",
volume = "70",
number = "4",
pages = "675-680",
doi = "10.2298/ABS180413029M"
}

Mitrović, M. J., Tatalović, N. R., Nikolic-Kokić, A. L., Ciraj-Bjelac, O. F., Krstić, N., Orescanin-Dusić, Z. S., Krstić, D. Z., Jovanović, Z. M., Blagojević, D. P.,& Lazarević Macanović, M.. (2018). Influence of absorbed radiation dose following computed tomography on the antioxidative status in rabbit testicles. in Archives of Biological Sciences
Srpsko biološko društvo, Beograd., 70(4), 675-680.
https://doi.org/10.2298/ABS180413029M

Mitrović MJ, Tatalović NR, Nikolic-Kokić AL, Ciraj-Bjelac OF, Krstić N, Orescanin-Dusić ZS, Krstić DZ, Jovanović ZM, Blagojević DP, Lazarević Macanović M. Influence of absorbed radiation dose following computed tomography on the antioxidative status in rabbit testicles. in Archives of Biological Sciences. 2018;70(4):675-680.
doi:10.2298/ABS180413029M .

Mitrović, Marko Jumake, Tatalović, Nikola R., Nikolic-Kokić, Aleksandra L., Ciraj-Bjelac, Olivera F., Krstić, Nikola, Orescanin-Dusić, Zorana S., Krstić, Dragana Z., Jovanović, Zoran M., Blagojević, Duško P., Lazarević Macanović, Mirjana, "Influence of absorbed radiation dose following computed tomography on the antioxidative status in rabbit testicles" in Archives of Biological Sciences, 70, no. 4 (2018):675-680,
https://doi.org/10.2298/ABS180413029M . .

TY  - JOUR
AU  - Dimitrijević, Mirjana
AU  - Arsenovic-Ranin, Nevena
AU  - Bufan, Biljana
AU  - Nacka-Aleksić, Mirjana
AU  - Lazarević Macanović, Mirjana
AU  - Milovanović, Petar
AU  - Durić, Marija
AU  - Sopta, Jelena
AU  - Leposavić, Gordana
PY  - 2018
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/1665
AB  - Collagen-induced arthritis (CIA) is a frequently used animal model of rheumatoid arthritis, human autoimmune disease that exhibits clear sex bias in incidence and clinical course. Female Dark Agouti rats immunized for CIA showed also greater incidence and higher arthritic score than their male counterparts. The study investigated sex differences in mechanisms controlling the primary immune responses in draining lymph nodes (dLNs), as a factor contributing to this dimorphism. The higher frequencies of CD4 + CD25 + Foxp3- cells, presumably activated effector T (Teff) cells, and IL-17+, IFN-gamma + and IL-17 + IFN-gamma + T cells were found in female compared with male rat dLNs. However, the frequency of CD4 + CD25 + Foxp3 + T regulatory cells (Treg) did not differ between sexes. Thus, CD4 + Teff cells/Treg ratio, and IL-17 + T cells/Treg and IFN-gamma + T cells/Treg ratios were higher in female than in male rats, and among them was found lower frequency of PD-1+ cells. This suggested less efficient control of (auto)immune Th1/Th17 cell responses in female rat dLNs. On the contrary, the frequency of IL-4 + T cells was lower in female than in male rat dLNs. Consistently, the ratio of serum levels of collagen-specific IgG2a (IFN-gamma-dependent, with an important pathogenic role in CIA) and IgG1 (IL-4-dependent) was shifted towards IgG2a in female compared with male rats. As a whole, the study suggests that sexual dimorphism in the control of T cell activation/polarization could contribute to sex bias in the susceptibility to CIA. Moreover, the study advises the use of animals of both sexes in the preclinical testing of new drugs for rheumatoid arthritis.
PB  - Academic Press Inc Elsevier Science, San Diego
T2  - Experimental and Molecular Pathology
T1  - Collagen-induced arthritis in Dark Agouti rats as a model for study of immunological sexual dimorphisms in the human disease
VL  - 105
IS  - 1
SP  - 10
EP  - 22
DO  - 10.1016/j.yexmp.2018.05.007
ER  - 

@article{
author = "Dimitrijević, Mirjana and Arsenovic-Ranin, Nevena and Bufan, Biljana and Nacka-Aleksić, Mirjana and Lazarević Macanović, Mirjana and Milovanović, Petar and Durić, Marija and Sopta, Jelena and Leposavić, Gordana",
year = "2018",
abstract = "Collagen-induced arthritis (CIA) is a frequently used animal model of rheumatoid arthritis, human autoimmune disease that exhibits clear sex bias in incidence and clinical course. Female Dark Agouti rats immunized for CIA showed also greater incidence and higher arthritic score than their male counterparts. The study investigated sex differences in mechanisms controlling the primary immune responses in draining lymph nodes (dLNs), as a factor contributing to this dimorphism. The higher frequencies of CD4 + CD25 + Foxp3- cells, presumably activated effector T (Teff) cells, and IL-17+, IFN-gamma + and IL-17 + IFN-gamma + T cells were found in female compared with male rat dLNs. However, the frequency of CD4 + CD25 + Foxp3 + T regulatory cells (Treg) did not differ between sexes. Thus, CD4 + Teff cells/Treg ratio, and IL-17 + T cells/Treg and IFN-gamma + T cells/Treg ratios were higher in female than in male rats, and among them was found lower frequency of PD-1+ cells. This suggested less efficient control of (auto)immune Th1/Th17 cell responses in female rat dLNs. On the contrary, the frequency of IL-4 + T cells was lower in female than in male rat dLNs. Consistently, the ratio of serum levels of collagen-specific IgG2a (IFN-gamma-dependent, with an important pathogenic role in CIA) and IgG1 (IL-4-dependent) was shifted towards IgG2a in female compared with male rats. As a whole, the study suggests that sexual dimorphism in the control of T cell activation/polarization could contribute to sex bias in the susceptibility to CIA. Moreover, the study advises the use of animals of both sexes in the preclinical testing of new drugs for rheumatoid arthritis.",
publisher = "Academic Press Inc Elsevier Science, San Diego",
journal = "Experimental and Molecular Pathology",
title = "Collagen-induced arthritis in Dark Agouti rats as a model for study of immunological sexual dimorphisms in the human disease",
volume = "105",
number = "1",
pages = "10-22",
doi = "10.1016/j.yexmp.2018.05.007"
}

Dimitrijević, M., Arsenovic-Ranin, N., Bufan, B., Nacka-Aleksić, M., Lazarević Macanović, M., Milovanović, P., Durić, M., Sopta, J.,& Leposavić, G.. (2018). Collagen-induced arthritis in Dark Agouti rats as a model for study of immunological sexual dimorphisms in the human disease. in Experimental and Molecular Pathology
Academic Press Inc Elsevier Science, San Diego., 105(1), 10-22.
https://doi.org/10.1016/j.yexmp.2018.05.007

Dimitrijević M, Arsenovic-Ranin N, Bufan B, Nacka-Aleksić M, Lazarević Macanović M, Milovanović P, Durić M, Sopta J, Leposavić G. Collagen-induced arthritis in Dark Agouti rats as a model for study of immunological sexual dimorphisms in the human disease. in Experimental and Molecular Pathology. 2018;105(1):10-22.
doi:10.1016/j.yexmp.2018.05.007 .

Dimitrijević, Mirjana, Arsenovic-Ranin, Nevena, Bufan, Biljana, Nacka-Aleksić, Mirjana, Lazarević Macanović, Mirjana, Milovanović, Petar, Durić, Marija, Sopta, Jelena, Leposavić, Gordana, "Collagen-induced arthritis in Dark Agouti rats as a model for study of immunological sexual dimorphisms in the human disease" in Experimental and Molecular Pathology, 105, no. 1 (2018):10-22,
https://doi.org/10.1016/j.yexmp.2018.05.007 . .

TY  - JOUR
AU  - Mitrović, Marko Jumake
AU  - Ciraj-Bjelac, Olivera F.
AU  - Orescanin-Dusić, Zorana S.
AU  - Blagojević, Duško P.
AU  - Nikolic-Kokić, Aleksandra L.
AU  - Tatalović, Nikola R.
AU  - Krstić, Nikola
AU  - Lazarević Macanović, Mirjana
PY  - 2017
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/1447
AB  - The objective of this study was to assess the radiation dose in computed tomography examinations of rabbits using different examination protocols and to correlate these values with the activity of antioxidant enzymes in their red blood cells following irradiation. The presented results revealed that a single, routine computed tomography scan exposure led to a different response of the activity of antioxidant enzymes in red blood cells regarding both dose and time. The results indicate that there is a dose threshold that is about 25 mGy. Doses below that level do not produce any significant changes in the level of antioxidant enzymes activity. On the other hand, the level just above that threshold had a significant impact on the antioxidant defence, but in a relatively short time period (2 hours after exposure), compared to the higher dose that requires a longer adaptive period.
PB  - Univerzitet u Beogradu - Institut za nuklearne nauke Vinča, Beograd
T2  - Nuclear Technology and Radiation Protection
T1  - Influence of radiation dose in computed tomography on antioxidant enzyme activity in rabbit erythrocytes
VL  - 32
IS  - 4
SP  - 342
EP  - 349
DO  - 10.2298/NTRP1704342M
ER  - 

@article{
author = "Mitrović, Marko Jumake and Ciraj-Bjelac, Olivera F. and Orescanin-Dusić, Zorana S. and Blagojević, Duško P. and Nikolic-Kokić, Aleksandra L. and Tatalović, Nikola R. and Krstić, Nikola and Lazarević Macanović, Mirjana",
year = "2017",
abstract = "The objective of this study was to assess the radiation dose in computed tomography examinations of rabbits using different examination protocols and to correlate these values with the activity of antioxidant enzymes in their red blood cells following irradiation. The presented results revealed that a single, routine computed tomography scan exposure led to a different response of the activity of antioxidant enzymes in red blood cells regarding both dose and time. The results indicate that there is a dose threshold that is about 25 mGy. Doses below that level do not produce any significant changes in the level of antioxidant enzymes activity. On the other hand, the level just above that threshold had a significant impact on the antioxidant defence, but in a relatively short time period (2 hours after exposure), compared to the higher dose that requires a longer adaptive period.",
publisher = "Univerzitet u Beogradu - Institut za nuklearne nauke Vinča, Beograd",
journal = "Nuclear Technology and Radiation Protection",
title = "Influence of radiation dose in computed tomography on antioxidant enzyme activity in rabbit erythrocytes",
volume = "32",
number = "4",
pages = "342-349",
doi = "10.2298/NTRP1704342M"
}

Mitrović, M. J., Ciraj-Bjelac, O. F., Orescanin-Dusić, Z. S., Blagojević, D. P., Nikolic-Kokić, A. L., Tatalović, N. R., Krstić, N.,& Lazarević Macanović, M.. (2017). Influence of radiation dose in computed tomography on antioxidant enzyme activity in rabbit erythrocytes. in Nuclear Technology and Radiation Protection
Univerzitet u Beogradu - Institut za nuklearne nauke Vinča, Beograd., 32(4), 342-349.
https://doi.org/10.2298/NTRP1704342M

Mitrović MJ, Ciraj-Bjelac OF, Orescanin-Dusić ZS, Blagojević DP, Nikolic-Kokić AL, Tatalović NR, Krstić N, Lazarević Macanović M. Influence of radiation dose in computed tomography on antioxidant enzyme activity in rabbit erythrocytes. in Nuclear Technology and Radiation Protection. 2017;32(4):342-349.
doi:10.2298/NTRP1704342M .

Mitrović, Marko Jumake, Ciraj-Bjelac, Olivera F., Orescanin-Dusić, Zorana S., Blagojević, Duško P., Nikolic-Kokić, Aleksandra L., Tatalović, Nikola R., Krstić, Nikola, Lazarević Macanović, Mirjana, "Influence of radiation dose in computed tomography on antioxidant enzyme activity in rabbit erythrocytes" in Nuclear Technology and Radiation Protection, 32, no. 4 (2017):342-349,
https://doi.org/10.2298/NTRP1704342M . .

TY  - JOUR
AU  - Lazarević Macanović, Mirjana
AU  - Radaković, N.
AU  - Mitrović, Marko Jumake
PY  - 2017
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/1440
AB  - Myelography is the radiological method of examination of the spinal column, and involves the application of contrast media into the subarachnoidal space in order to diagnose different pathological conditions. The formerly used application of oil-based contrast media did not yield consistent, satisfactory results and also carried certain risks. Due to the poor mixing of oil-based contrast agents with cerebrospinal fluid, distribution along the spinal canal was uneven, excretion from the body very slow, and their application often caused chronic inflammation. For these reasons, oilbased contrast media have since been replaced with low osmolality, water soluble, non-ionic contrasts. In contemporary radiology, the commonly used contrast media for myelography are metrizamide, iopamidol and iohexol. Metrizamide is often used as an isotonic solution containing 170 mg I/mL, while iopamidol and iohexol are slightly hypertonic, containing approximately 300 mg I/mL. The application of these contrast agents can also produce a wide range of complications in clinical practice, such as neurological exacerbation, hyperaesthesia, vomiting and apnea. These symptoms are usually a consequence of metrizamide, but may also occur following the administration of iopamidol and iohexsol. In that case, complications are mostly transient. Regarding the facts presented, a large number of literature data are outlined in this paper. Moreover, different author reports are described regarding the selection of contrast agents, their method of application, and the possible complications that can occur as a result of their usage.
PB  - Croatian Veterinary Institute
T2  - Veterinarska Stanica
T1  - Contrast media for myelography and possible complications following their application
T1  - Kontrastna sredstva za mijelografiju i moguće komplikacije nakon njihove primjene
VL  - 48
IS  - 5
SP  - 365
EP  - 378
UR  - https://hdl.handle.net/21.15107/rcub_veterinar_1440
ER  - 

@article{
author = "Lazarević Macanović, Mirjana and Radaković, N. and Mitrović, Marko Jumake",
year = "2017",
abstract = "Myelography is the radiological method of examination of the spinal column, and involves the application of contrast media into the subarachnoidal space in order to diagnose different pathological conditions. The formerly used application of oil-based contrast media did not yield consistent, satisfactory results and also carried certain risks. Due to the poor mixing of oil-based contrast agents with cerebrospinal fluid, distribution along the spinal canal was uneven, excretion from the body very slow, and their application often caused chronic inflammation. For these reasons, oilbased contrast media have since been replaced with low osmolality, water soluble, non-ionic contrasts. In contemporary radiology, the commonly used contrast media for myelography are metrizamide, iopamidol and iohexol. Metrizamide is often used as an isotonic solution containing 170 mg I/mL, while iopamidol and iohexol are slightly hypertonic, containing approximately 300 mg I/mL. The application of these contrast agents can also produce a wide range of complications in clinical practice, such as neurological exacerbation, hyperaesthesia, vomiting and apnea. These symptoms are usually a consequence of metrizamide, but may also occur following the administration of iopamidol and iohexsol. In that case, complications are mostly transient. Regarding the facts presented, a large number of literature data are outlined in this paper. Moreover, different author reports are described regarding the selection of contrast agents, their method of application, and the possible complications that can occur as a result of their usage.",
publisher = "Croatian Veterinary Institute",
journal = "Veterinarska Stanica",
title = "Contrast media for myelography and possible complications following their application, Kontrastna sredstva za mijelografiju i moguće komplikacije nakon njihove primjene",
volume = "48",
number = "5",
pages = "365-378",
url = "https://hdl.handle.net/21.15107/rcub_veterinar_1440"
}

Lazarević Macanović, M., Radaković, N.,& Mitrović, M. J.. (2017). Contrast media for myelography and possible complications following their application. in Veterinarska Stanica
Croatian Veterinary Institute., 48(5), 365-378.
https://hdl.handle.net/21.15107/rcub_veterinar_1440

Lazarević Macanović M, Radaković N, Mitrović MJ. Contrast media for myelography and possible complications following their application. in Veterinarska Stanica. 2017;48(5):365-378.
https://hdl.handle.net/21.15107/rcub_veterinar_1440 .

Lazarević Macanović, Mirjana, Radaković, N., Mitrović, Marko Jumake, "Contrast media for myelography and possible complications following their application" in Veterinarska Stanica, 48, no. 5 (2017):365-378,
https://hdl.handle.net/21.15107/rcub_veterinar_1440 .

TY  - JOUR
AU  - Mitrović, Marko Jumake
AU  - Samoy, Yves
AU  - Lazarević Macanović, Mirjana
AU  - van, Bree Henri
AU  - Gielen, Ingrid
PY  - 2017
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/1459
AB  - An unusual case of forelimb lameness in a three-year-old German Shepherd has been described. An incomplete ossification of the humeral condyle (IOHC) in both elbows has been diagnosed, which is a rare condition in this breed. The original radiographs and clinical examination were inconclusive. The diagnosis was established after scintigraphy proving elbow involvement and followed by a CT examination of both elbows. An arthroscopic examination showed a cleft in the articular cartilage between both humeral condyles. Because of the absence of lameness at the moment of admittance, initially conservative treatment was performed, which consisted of rest and avoiding trauma. The dog remained lameness-free during one year, where after he showed severe lameness in the left front leg. Although a second CT examination showed some progress of the lesions, it was decided to treat the left elbow with forage and physiotherapy consisting of laser treatment and therapeutic ultrasound. The dog responded favorably to the therapy and remains free of lameness to date. The optimal treatment of this disease remains debatable but the results of the treatment of this patient suggest that forage combined with physiotherapy could offer a justifiable option.
AB  - U ovom radu je prikazan slučaj nepotpune osifikacije kondilusa ramene kosti kod nemačkog ovčara starog tri godine. Ovo patološko stanje se retko javlja kod pomenute rase pasa, a klinički se ispoljava hromošću prednjih ekstremiteta. Na osnovu kliničkog pregleda i analize rendgenskih snimaka, kod obolele životinje nije bilo moguće postaviti dijagnozu. Oboljenje je, međutim, uspešno dijagnostikovano metodom scintigrafije i kompjuterizovane tomografije, dok su artroskopskim pregledom verifikovana oštećenja na zglobnim hrskavicama u interkondilarnom delu ramene kosti. S obzirom na to da u trenutku prijema pacijenta intermitentna hromost nije bila uočljiva, preporučeno je samo smanjenje fizičke aktivnosti životinje. Iako klinički znaci bolesti nisu bili prisutni tokom godinu dana, hromost prednjeg levog ekstremiteta se nakon tog perioda ponovo javila. Pri kontrolnom pregledu metodom kompjuterizovane tomografije uočeno je progrediranje oštećenja. Pored korekcije ishrane, uključena je i fizikalna terapija koja je podrazumevala primenu lasera i ultrazvučnih talasa. Na upotrebu ove vrste terapije je pas povoljno reagovao i do sada se hromost nije ponovo javila. S obzirom na postignute rezultate kod ovog pacijenta, kao i to da ne postoji specifičan tretman nepotpune osifikacije kondilusa ramene kosti, korekcija ishrane i fizikalna terapija bi mogle predstavljati dobru opciju u tretiranju ovog oboljenja.
PB  - Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd
T2  - Veterinarski Glasnik
T1  - Incomplete ossification of the humeral condyle (IOHC) in a three-year-old German Shepherd
T1  - Nepotpuna osifikacija kondilusa ramene kosti dijagnostikovana kod nemačkog ovčara starog tri godine
VL  - 71
IS  - 2
SP  - 123
EP  - 133
DO  - 10.2298/VETGL1702123M
ER  - 

@article{
author = "Mitrović, Marko Jumake and Samoy, Yves and Lazarević Macanović, Mirjana and van, Bree Henri and Gielen, Ingrid",
year = "2017",
abstract = "An unusual case of forelimb lameness in a three-year-old German Shepherd has been described. An incomplete ossification of the humeral condyle (IOHC) in both elbows has been diagnosed, which is a rare condition in this breed. The original radiographs and clinical examination were inconclusive. The diagnosis was established after scintigraphy proving elbow involvement and followed by a CT examination of both elbows. An arthroscopic examination showed a cleft in the articular cartilage between both humeral condyles. Because of the absence of lameness at the moment of admittance, initially conservative treatment was performed, which consisted of rest and avoiding trauma. The dog remained lameness-free during one year, where after he showed severe lameness in the left front leg. Although a second CT examination showed some progress of the lesions, it was decided to treat the left elbow with forage and physiotherapy consisting of laser treatment and therapeutic ultrasound. The dog responded favorably to the therapy and remains free of lameness to date. The optimal treatment of this disease remains debatable but the results of the treatment of this patient suggest that forage combined with physiotherapy could offer a justifiable option., U ovom radu je prikazan slučaj nepotpune osifikacije kondilusa ramene kosti kod nemačkog ovčara starog tri godine. Ovo patološko stanje se retko javlja kod pomenute rase pasa, a klinički se ispoljava hromošću prednjih ekstremiteta. Na osnovu kliničkog pregleda i analize rendgenskih snimaka, kod obolele životinje nije bilo moguće postaviti dijagnozu. Oboljenje je, međutim, uspešno dijagnostikovano metodom scintigrafije i kompjuterizovane tomografije, dok su artroskopskim pregledom verifikovana oštećenja na zglobnim hrskavicama u interkondilarnom delu ramene kosti. S obzirom na to da u trenutku prijema pacijenta intermitentna hromost nije bila uočljiva, preporučeno je samo smanjenje fizičke aktivnosti životinje. Iako klinički znaci bolesti nisu bili prisutni tokom godinu dana, hromost prednjeg levog ekstremiteta se nakon tog perioda ponovo javila. Pri kontrolnom pregledu metodom kompjuterizovane tomografije uočeno je progrediranje oštećenja. Pored korekcije ishrane, uključena je i fizikalna terapija koja je podrazumevala primenu lasera i ultrazvučnih talasa. Na upotrebu ove vrste terapije je pas povoljno reagovao i do sada se hromost nije ponovo javila. S obzirom na postignute rezultate kod ovog pacijenta, kao i to da ne postoji specifičan tretman nepotpune osifikacije kondilusa ramene kosti, korekcija ishrane i fizikalna terapija bi mogle predstavljati dobru opciju u tretiranju ovog oboljenja.",
publisher = "Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd",
journal = "Veterinarski Glasnik",
title = "Incomplete ossification of the humeral condyle (IOHC) in a three-year-old German Shepherd, Nepotpuna osifikacija kondilusa ramene kosti dijagnostikovana kod nemačkog ovčara starog tri godine",
volume = "71",
number = "2",
pages = "123-133",
doi = "10.2298/VETGL1702123M"
}

Mitrović, M. J., Samoy, Y., Lazarević Macanović, M., van, B. H.,& Gielen, I.. (2017). Incomplete ossification of the humeral condyle (IOHC) in a three-year-old German Shepherd. in Veterinarski Glasnik
Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd., 71(2), 123-133.
https://doi.org/10.2298/VETGL1702123M

Mitrović MJ, Samoy Y, Lazarević Macanović M, van BH, Gielen I. Incomplete ossification of the humeral condyle (IOHC) in a three-year-old German Shepherd. in Veterinarski Glasnik. 2017;71(2):123-133.
doi:10.2298/VETGL1702123M .

Mitrović, Marko Jumake, Samoy, Yves, Lazarević Macanović, Mirjana, van, Bree Henri, Gielen, Ingrid, "Incomplete ossification of the humeral condyle (IOHC) in a three-year-old German Shepherd" in Veterinarski Glasnik, 71, no. 2 (2017):123-133,
https://doi.org/10.2298/VETGL1702123M . .

TY  - JOUR
AU  - Mitrović, Branislava
AU  - Jovanović, Milijan
AU  - Lazarević Macanović, Mirjana
AU  - Janacković, Đorđe
AU  - Krstić, Nikola
AU  - Stojanović, Mirjana
AU  - Mirilović, Milorad
PY  - 2015
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/1195
AB  - The use of phosphate mineral products in animal nutrition, as a major source of phosphor and calcium, can lead to uranium entering the food chain. The aim of the present study was to determine the protective effect of natural sepiolite and sepiolite treated with acid for broilers after oral intake of uranium. The broilers were contaminated for 7 days with 25 mg/uranyl nitrate per day. Two different adsorbents (natural sepiolite and sepiolite treated with acid) were given via gastric tube immediately after the oral administration of uranium. Natural sepiolite reduced uranium distribution by 57 % in kidney, 80 % in liver, 42 % in brain, and 56 % in muscle. A lower protective effect was observed after the administration of sepiolite treated with acid, resulting in significant damage of intestinal villi in the form of shortening, fragmentation, and necrosis, and histopathological lesions on kidney in the form of edema and abruption of epithelial cells in tubules. When broilers received only sepiolite treated with acid (no uranyl nitrate), shortening of intestinal villi occurred. Kidney injuries were evident when uranium concentrations in kidney were 0.88 and 1.25 A mu g/g dry weight. It is concluded that adding of natural sepiolite to the diets of broilers can reduce uranium distribution in organs by significant amount without adverse side effects.
PB  - Springer, New York
T2  - Radiation and Environmental Biophysics
T1  - Efficiency of sepiolite in broilers diet as uranium adsorbent
VL  - 54
IS  - 2
SP  - 217
EP  - 224
DO  - 10.1007/s00411-015-0589-2
ER  - 

@article{
author = "Mitrović, Branislava and Jovanović, Milijan and Lazarević Macanović, Mirjana and Janacković, Đorđe and Krstić, Nikola and Stojanović, Mirjana and Mirilović, Milorad",
year = "2015",
abstract = "The use of phosphate mineral products in animal nutrition, as a major source of phosphor and calcium, can lead to uranium entering the food chain. The aim of the present study was to determine the protective effect of natural sepiolite and sepiolite treated with acid for broilers after oral intake of uranium. The broilers were contaminated for 7 days with 25 mg/uranyl nitrate per day. Two different adsorbents (natural sepiolite and sepiolite treated with acid) were given via gastric tube immediately after the oral administration of uranium. Natural sepiolite reduced uranium distribution by 57 % in kidney, 80 % in liver, 42 % in brain, and 56 % in muscle. A lower protective effect was observed after the administration of sepiolite treated with acid, resulting in significant damage of intestinal villi in the form of shortening, fragmentation, and necrosis, and histopathological lesions on kidney in the form of edema and abruption of epithelial cells in tubules. When broilers received only sepiolite treated with acid (no uranyl nitrate), shortening of intestinal villi occurred. Kidney injuries were evident when uranium concentrations in kidney were 0.88 and 1.25 A mu g/g dry weight. It is concluded that adding of natural sepiolite to the diets of broilers can reduce uranium distribution in organs by significant amount without adverse side effects.",
publisher = "Springer, New York",
journal = "Radiation and Environmental Biophysics",
title = "Efficiency of sepiolite in broilers diet as uranium adsorbent",
volume = "54",
number = "2",
pages = "217-224",
doi = "10.1007/s00411-015-0589-2"
}

Mitrović, B., Jovanović, M., Lazarević Macanović, M., Janacković, Đ., Krstić, N., Stojanović, M.,& Mirilović, M.. (2015). Efficiency of sepiolite in broilers diet as uranium adsorbent. in Radiation and Environmental Biophysics
Springer, New York., 54(2), 217-224.
https://doi.org/10.1007/s00411-015-0589-2

Mitrović B, Jovanović M, Lazarević Macanović M, Janacković Đ, Krstić N, Stojanović M, Mirilović M. Efficiency of sepiolite in broilers diet as uranium adsorbent. in Radiation and Environmental Biophysics. 2015;54(2):217-224.
doi:10.1007/s00411-015-0589-2 .

Mitrović, Branislava, Jovanović, Milijan, Lazarević Macanović, Mirjana, Janacković, Đorđe, Krstić, Nikola, Stojanović, Mirjana, Mirilović, Milorad, "Efficiency of sepiolite in broilers diet as uranium adsorbent" in Radiation and Environmental Biophysics, 54, no. 2 (2015):217-224,
https://doi.org/10.1007/s00411-015-0589-2 . .

TY  - JOUR
AU  - Krstić, Nikola
AU  - Lazarević Macanović, Mirjana
AU  - Mitrović, Branislava
AU  - Mitrović, Marko Jumake
PY  - 2015
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/1204
AB  - Dental diseases in dogs and cats are of increasing importance in veterinary practice. If not diagnosed and treated on time, they can significantly affect the quality of life and pet health as well. Roentgenography of orofacial system, as a part of veterinary dentistry, is an important diagnostic tool that provides insight into diseases and irregularities of the teeth, shows macrostructure of bone parts, and also may indicate the etiology and genesis of various pathological conditions of the teeth. The objective of this paper is to point out to most common pathologies which small animal veterinary dentistry daily meets, as well as to foster the systematic development in this area in order to find more quality to both diagnostic and therapeutic procedures.
AB  - Proučavanje dentalnih oboljenja pasa i mačaka ima sve veći značaj u veterinarskoj praksi. Ukoliko se ne dijagnostikuju i ne leče na vreme, mogu značajno da utiču na kvalitet života i zdravlje kućnih ljubimaca. Rendgenografija orofacijalnog sistema, kao deo veterinarske stomatologije, je važan dijagnostički metod koji pruža uvid u oboljenja i nepravilnosti zuba, omogućava prikaz makrostrukture koštanih delova, a može ukazati i na etiologiju i genezu različitih patoloških stanja zubala. Svrha ovog rada je da ukaže na najčešće patološke pojave sa kojima se veterinarska stomatologija malih životinja svakodnevno suočava, kao i da podstakne sistematski razvoj ove oblasti u cilju nalaženja što kvalitetnijih kako dijagnostičkih tako i terapijskih postupaka.
PB  - Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd
T2  - Veterinarski Glasnik
T1  - X-ray diagnostics of most common periodontal diseases in dogs and cats
T1  - Rendgenska dijagnostika najčešćih oboljenja periodoncijuma pasa i mačaka
VL  - 69
IS  - 1-2
SP  - 101
EP  - 110
DO  - 10.2298/VETGL1502101K
ER  - 

@article{
author = "Krstić, Nikola and Lazarević Macanović, Mirjana and Mitrović, Branislava and Mitrović, Marko Jumake",
year = "2015",
abstract = "Dental diseases in dogs and cats are of increasing importance in veterinary practice. If not diagnosed and treated on time, they can significantly affect the quality of life and pet health as well. Roentgenography of orofacial system, as a part of veterinary dentistry, is an important diagnostic tool that provides insight into diseases and irregularities of the teeth, shows macrostructure of bone parts, and also may indicate the etiology and genesis of various pathological conditions of the teeth. The objective of this paper is to point out to most common pathologies which small animal veterinary dentistry daily meets, as well as to foster the systematic development in this area in order to find more quality to both diagnostic and therapeutic procedures., Proučavanje dentalnih oboljenja pasa i mačaka ima sve veći značaj u veterinarskoj praksi. Ukoliko se ne dijagnostikuju i ne leče na vreme, mogu značajno da utiču na kvalitet života i zdravlje kućnih ljubimaca. Rendgenografija orofacijalnog sistema, kao deo veterinarske stomatologije, je važan dijagnostički metod koji pruža uvid u oboljenja i nepravilnosti zuba, omogućava prikaz makrostrukture koštanih delova, a može ukazati i na etiologiju i genezu različitih patoloških stanja zubala. Svrha ovog rada je da ukaže na najčešće patološke pojave sa kojima se veterinarska stomatologija malih životinja svakodnevno suočava, kao i da podstakne sistematski razvoj ove oblasti u cilju nalaženja što kvalitetnijih kako dijagnostičkih tako i terapijskih postupaka.",
publisher = "Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd",
journal = "Veterinarski Glasnik",
title = "X-ray diagnostics of most common periodontal diseases in dogs and cats, Rendgenska dijagnostika najčešćih oboljenja periodoncijuma pasa i mačaka",
volume = "69",
number = "1-2",
pages = "101-110",
doi = "10.2298/VETGL1502101K"
}

Krstić, N., Lazarević Macanović, M., Mitrović, B.,& Mitrović, M. J.. (2015). X-ray diagnostics of most common periodontal diseases in dogs and cats. in Veterinarski Glasnik
Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd., 69(1-2), 101-110.
https://doi.org/10.2298/VETGL1502101K

Krstić N, Lazarević Macanović M, Mitrović B, Mitrović MJ. X-ray diagnostics of most common periodontal diseases in dogs and cats. in Veterinarski Glasnik. 2015;69(1-2):101-110.
doi:10.2298/VETGL1502101K .

Krstić, Nikola, Lazarević Macanović, Mirjana, Mitrović, Branislava, Mitrović, Marko Jumake, "X-ray diagnostics of most common periodontal diseases in dogs and cats" in Veterinarski Glasnik, 69, no. 1-2 (2015):101-110,
https://doi.org/10.2298/VETGL1502101K . .

TY  - JOUR
AU  - Francuski, Jelena
AU  - Radovanović, Anita
AU  - Andrić, Nenad
AU  - Krstić, Vanja
AU  - Bogdanović, Dragan
AU  - Hadzić, V.
AU  - Todorović, V.
AU  - Lazarević Macanović, Mirjana
AU  - Petit, S. Sourice
AU  - Beck-Cormier, Sarah
AU  - Guicheux, J.
AU  - Gauthier, O.
AU  - Kovačević-Filipović, Milica
PY  - 2014
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/1093
AB  - The aims of this study were to define age-related histological changes in the articular cartilage of the stifle joint in non-chondrodystrophic dogs and to determine whether physical activity has a positive impact on preservation of cartilage structure during ageing. Twenty-eight German shepherd dogs were included in the study. These dogs had no evidence of joint inflammation as defined by clinical assessment, radiology and synovial fluid analysis (specifically absence of synovial fluid serum amyloid A). The dogs were grouped as young working (n = 4), young non-working (n = 5), aged working (n = 13) and aged non-working (n = 6) animals. Gross changes in the stifle joints were recorded and biopsy samples of femoral and tibial articular cartilage were evaluated for thickness; chondrocyte number, density, surface area and morphology; isogenous group morphology; tidemark integrity; subchondral bone structure; presence of proteoglycans/glycosaminoglycans; and expression of type I, II and X collagens. The major age-related changes, not related to type of physical activity, included elevated chondrocyte density and thinning of tibial cartilage and increased chondrocyte surface area in the superficial and intermediate zone of the femoral cartilage. There was also expression of type X collagen in the femoral and tibial calcified and non-calcified cartilage; however, type X collagen was not detected in the superficial zone of old working dogs. Therefore, ageing, with or without physical activity, leads to slight cartilage degeneration, while physical activity modulates the synthesis of type X collagen in the superficial cartilage zone, partially preserving the structure of hyaline cartilage.
PB  - Elsevier Sci Ltd, Oxford
T2  - Journal of Comparative Pathology
T1  - Age-related Changes in the Articular Cartilage of the Stifle Joint in Non-working and Working German Shepherd Dogs
VL  - 151
IS  - 4
SP  - 363
EP  - 374
DO  - 10.1016/j.jcpa.2014.09.002
ER  - 

@article{
author = "Francuski, Jelena and Radovanović, Anita and Andrić, Nenad and Krstić, Vanja and Bogdanović, Dragan and Hadzić, V. and Todorović, V. and Lazarević Macanović, Mirjana and Petit, S. Sourice and Beck-Cormier, Sarah and Guicheux, J. and Gauthier, O. and Kovačević-Filipović, Milica",
year = "2014",
abstract = "The aims of this study were to define age-related histological changes in the articular cartilage of the stifle joint in non-chondrodystrophic dogs and to determine whether physical activity has a positive impact on preservation of cartilage structure during ageing. Twenty-eight German shepherd dogs were included in the study. These dogs had no evidence of joint inflammation as defined by clinical assessment, radiology and synovial fluid analysis (specifically absence of synovial fluid serum amyloid A). The dogs were grouped as young working (n = 4), young non-working (n = 5), aged working (n = 13) and aged non-working (n = 6) animals. Gross changes in the stifle joints were recorded and biopsy samples of femoral and tibial articular cartilage were evaluated for thickness; chondrocyte number, density, surface area and morphology; isogenous group morphology; tidemark integrity; subchondral bone structure; presence of proteoglycans/glycosaminoglycans; and expression of type I, II and X collagens. The major age-related changes, not related to type of physical activity, included elevated chondrocyte density and thinning of tibial cartilage and increased chondrocyte surface area in the superficial and intermediate zone of the femoral cartilage. There was also expression of type X collagen in the femoral and tibial calcified and non-calcified cartilage; however, type X collagen was not detected in the superficial zone of old working dogs. Therefore, ageing, with or without physical activity, leads to slight cartilage degeneration, while physical activity modulates the synthesis of type X collagen in the superficial cartilage zone, partially preserving the structure of hyaline cartilage.",
publisher = "Elsevier Sci Ltd, Oxford",
journal = "Journal of Comparative Pathology",
title = "Age-related Changes in the Articular Cartilage of the Stifle Joint in Non-working and Working German Shepherd Dogs",
volume = "151",
number = "4",
pages = "363-374",
doi = "10.1016/j.jcpa.2014.09.002"
}

Francuski, J., Radovanović, A., Andrić, N., Krstić, V., Bogdanović, D., Hadzić, V., Todorović, V., Lazarević Macanović, M., Petit, S. S., Beck-Cormier, S., Guicheux, J., Gauthier, O.,& Kovačević-Filipović, M.. (2014). Age-related Changes in the Articular Cartilage of the Stifle Joint in Non-working and Working German Shepherd Dogs. in Journal of Comparative Pathology
Elsevier Sci Ltd, Oxford., 151(4), 363-374.
https://doi.org/10.1016/j.jcpa.2014.09.002

Francuski J, Radovanović A, Andrić N, Krstić V, Bogdanović D, Hadzić V, Todorović V, Lazarević Macanović M, Petit SS, Beck-Cormier S, Guicheux J, Gauthier O, Kovačević-Filipović M. Age-related Changes in the Articular Cartilage of the Stifle Joint in Non-working and Working German Shepherd Dogs. in Journal of Comparative Pathology. 2014;151(4):363-374.
doi:10.1016/j.jcpa.2014.09.002 .

Francuski, Jelena, Radovanović, Anita, Andrić, Nenad, Krstić, Vanja, Bogdanović, Dragan, Hadzić, V., Todorović, V., Lazarević Macanović, Mirjana, Petit, S. Sourice, Beck-Cormier, Sarah, Guicheux, J., Gauthier, O., Kovačević-Filipović, Milica, "Age-related Changes in the Articular Cartilage of the Stifle Joint in Non-working and Working German Shepherd Dogs" in Journal of Comparative Pathology, 151, no. 4 (2014):363-374,
https://doi.org/10.1016/j.jcpa.2014.09.002 . .

TY  - JOUR
AU  - Lazarević Macanović, Mirjana
AU  - Mitrović, Marko Jumake
AU  - Krstić, Nikola
AU  - Vasić, Jugoslav
AU  - Francuski, Jelena
AU  - Mitrović, Branislava
PY  - 2014
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/1136
AB  - Changes caused by joint diseases that are manifested in X-ray are very diverse. Some of them are present in all arthroparthies while some are specific to certain diseases. For all the arthropathies it is specific that the duration of a disease significantly influences the presence and intensity of radiological changes. In this paper there analyzed in detail some basic radiological joint diseases manifestations such as: distension of the joint capsule, change of size (width) of the joint space, change of position of corresponding bones within the joint, change in quality of subchondral bone, the appearance of intra-articular mineralization and calcified structures, as well as the presence of perichondral and periarticular bone proliferations. Beside that, there are described in detail arthropathies of different etiology.
AB  - Promene kojim se oboljenja zglobova manifestuju u rendgenskoj slici su veoma raznovrsne. Neke od njih postoje kod svih artropatija dok su druge specificne samo za pojedina oboljenja. Za sve artropatije je karakteristično da dužina trajanja bolesti značajno utiče na zastupljenost i intenzitet radioloških promena. U radu su detaljno analizirane osnovne radiološke manifestacije oboljenja zglobova kao što su: distenzija zglobne kapsule, promena veličine (širine) zglobnog prostora, promena položaja korespondirajućih kostiju u okviru zgloba, promena kvaliteta subhobdralne kosti, pojava intraartikularnih mineralizacija i kalcifikovanih struktura, kao i prisustvo perihondralnih i periartikularnih koštanih proliferacija. Pored toga, detaljno su opisane i artropatije različite etiologije.
PB  - Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd
T2  - Veterinarski Glasnik
T1  - Manifestations of joint disease of domestic carnivores in X-ray view
T1  - Manifestacija boleznej sustavov domašnih plotojadnyh na rentgenovskih snimkah
T1  - Manifestacije oboljenja zglobova domaćih mesojeda u rendgenskoj slici
VL  - 68
IS  - 5-6
SP  - 349
EP  - 362
DO  - 10.2298/VETGL1406349L
ER  - 

@article{
author = "Lazarević Macanović, Mirjana and Mitrović, Marko Jumake and Krstić, Nikola and Vasić, Jugoslav and Francuski, Jelena and Mitrović, Branislava",
year = "2014",
abstract = "Changes caused by joint diseases that are manifested in X-ray are very diverse. Some of them are present in all arthroparthies while some are specific to certain diseases. For all the arthropathies it is specific that the duration of a disease significantly influences the presence and intensity of radiological changes. In this paper there analyzed in detail some basic radiological joint diseases manifestations such as: distension of the joint capsule, change of size (width) of the joint space, change of position of corresponding bones within the joint, change in quality of subchondral bone, the appearance of intra-articular mineralization and calcified structures, as well as the presence of perichondral and periarticular bone proliferations. Beside that, there are described in detail arthropathies of different etiology., Promene kojim se oboljenja zglobova manifestuju u rendgenskoj slici su veoma raznovrsne. Neke od njih postoje kod svih artropatija dok su druge specificne samo za pojedina oboljenja. Za sve artropatije je karakteristično da dužina trajanja bolesti značajno utiče na zastupljenost i intenzitet radioloških promena. U radu su detaljno analizirane osnovne radiološke manifestacije oboljenja zglobova kao što su: distenzija zglobne kapsule, promena veličine (širine) zglobnog prostora, promena položaja korespondirajućih kostiju u okviru zgloba, promena kvaliteta subhobdralne kosti, pojava intraartikularnih mineralizacija i kalcifikovanih struktura, kao i prisustvo perihondralnih i periartikularnih koštanih proliferacija. Pored toga, detaljno su opisane i artropatije različite etiologije.",
publisher = "Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd",
journal = "Veterinarski Glasnik",
title = "Manifestations of joint disease of domestic carnivores in X-ray view, Manifestacija boleznej sustavov domašnih plotojadnyh na rentgenovskih snimkah, Manifestacije oboljenja zglobova domaćih mesojeda u rendgenskoj slici",
volume = "68",
number = "5-6",
pages = "349-362",
doi = "10.2298/VETGL1406349L"
}

Lazarević Macanović, M., Mitrović, M. J., Krstić, N., Vasić, J., Francuski, J.,& Mitrović, B.. (2014). Manifestations of joint disease of domestic carnivores in X-ray view. in Veterinarski Glasnik
Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd., 68(5-6), 349-362.
https://doi.org/10.2298/VETGL1406349L

Lazarević Macanović M, Mitrović MJ, Krstić N, Vasić J, Francuski J, Mitrović B. Manifestations of joint disease of domestic carnivores in X-ray view. in Veterinarski Glasnik. 2014;68(5-6):349-362.
doi:10.2298/VETGL1406349L .

Lazarević Macanović, Mirjana, Mitrović, Marko Jumake, Krstić, Nikola, Vasić, Jugoslav, Francuski, Jelena, Mitrović, Branislava, "Manifestations of joint disease of domestic carnivores in X-ray view" in Veterinarski Glasnik, 68, no. 5-6 (2014):349-362,
https://doi.org/10.2298/VETGL1406349L . .

TY  - JOUR
AU  - Mitrović, Branislava
AU  - Vitorović, Gordana
AU  - Jovanović, Milijan
AU  - Lazarević Macanović, Mirjana
AU  - Andrić, Velibor
AU  - Stojanović, Mirjana
AU  - Daković, Aleksandra
AU  - Vitorović, Duško
PY  - 2014
UR  - https://vet-erinar.vet.bg.ac.rs/handle/123456789/1103
AB  - The aim of the present study was to investigate the distribution of uranium (uranyl nitrate hexahydrate, UN) in muscle and organs (kidney, liver, and brain) of broilers, after a 7-day contamination with UN and administration of two different adsorbents (organobentonite and organozeolite). The birds were contaminated during 7 days with 25 mg/UN per day. Adsorbents were given via gastric tube, immediately after contamination with UN. In group 1 that did not receive any adsorbents, histopathological changes in the contaminated broilers were observed in small intestine, liver, and kidney in the form of necrosis of intestinal villi, oedema and cytoplasmic vacuolation of hepatocytes, and dystrophic changes in the kidney tubules epithelium. Organobentonite administered via gastric tube (group 2) reduced uranium distribution by 66 % in kidney, 81 % in liver, and 34 % in brain. In group 3, administration of organozeolite reduced uranium distribution by 67 % in kidney, 68 % in liver, and 49 % in brain. In groups 2 and 3, where the broilers received adsorbents immediately after the UN contamination, no histopathological lesions were observed.
PB  - Springer, New York
T2  - Radiation and Environmental Biophysics
T1  - Uranium distribution in broiler organs and possibilities for protection
VL  - 53
IS  - 1
SP  - 151
EP  - 157
DO  - 10.1007/s00411-013-0496-3
ER  - 

@article{
author = "Mitrović, Branislava and Vitorović, Gordana and Jovanović, Milijan and Lazarević Macanović, Mirjana and Andrić, Velibor and Stojanović, Mirjana and Daković, Aleksandra and Vitorović, Duško",
year = "2014",
abstract = "The aim of the present study was to investigate the distribution of uranium (uranyl nitrate hexahydrate, UN) in muscle and organs (kidney, liver, and brain) of broilers, after a 7-day contamination with UN and administration of two different adsorbents (organobentonite and organozeolite). The birds were contaminated during 7 days with 25 mg/UN per day. Adsorbents were given via gastric tube, immediately after contamination with UN. In group 1 that did not receive any adsorbents, histopathological changes in the contaminated broilers were observed in small intestine, liver, and kidney in the form of necrosis of intestinal villi, oedema and cytoplasmic vacuolation of hepatocytes, and dystrophic changes in the kidney tubules epithelium. Organobentonite administered via gastric tube (group 2) reduced uranium distribution by 66 % in kidney, 81 % in liver, and 34 % in brain. In group 3, administration of organozeolite reduced uranium distribution by 67 % in kidney, 68 % in liver, and 49 % in brain. In groups 2 and 3, where the broilers received adsorbents immediately after the UN contamination, no histopathological lesions were observed.",
publisher = "Springer, New York",
journal = "Radiation and Environmental Biophysics",
title = "Uranium distribution in broiler organs and possibilities for protection",
volume = "53",
number = "1",
pages = "151-157",
doi = "10.1007/s00411-013-0496-3"
}

Mitrović, B., Vitorović, G., Jovanović, M., Lazarević Macanović, M., Andrić, V., Stojanović, M., Daković, A.,& Vitorović, D.. (2014). Uranium distribution in broiler organs and possibilities for protection. in Radiation and Environmental Biophysics
Springer, New York., 53(1), 151-157.
https://doi.org/10.1007/s00411-013-0496-3

Mitrović B, Vitorović G, Jovanović M, Lazarević Macanović M, Andrić V, Stojanović M, Daković A, Vitorović D. Uranium distribution in broiler organs and possibilities for protection. in Radiation and Environmental Biophysics. 2014;53(1):151-157.
doi:10.1007/s00411-013-0496-3 .

Mitrović, Branislava, Vitorović, Gordana, Jovanović, Milijan, Lazarević Macanović, Mirjana, Andrić, Velibor, Stojanović, Mirjana, Daković, Aleksandra, Vitorović, Duško, "Uranium distribution in broiler organs and possibilities for protection" in Radiation and Environmental Biophysics, 53, no. 1 (2014):151-157,
https://doi.org/10.1007/s00411-013-0496-3 . .